Vital Signs: Reading Critical Developments in Global Health
Recruitment process behind closed doors: the Global Health Campus is home to the world's leading global health organisations such as Unitaid and the Global Fund.
At Unitaid and Global Fund headquarters on the outskirts of Geneva, agency leaders are struggling to adapt their work to a global health landscape dominated by the largest funding crisis in decades.

Last week, one phrase — “self-reliance” — did more work in global health than any medicine, as global agencies continue operationalising donor retreats they can no longer disguise. The strategy’s real-world test is unfolding in eastern Congo, where the fastest-growing Ebola outbreak on record is outrunning a struggling response.

The institutions of global health spent the week managing their own diminishment, and the language they used to describe it deserves closer scrutiny.  

The Global Fund’s eighth replenishment secured $12.64 billion against its $18 billion target to fight AIDS, tuberculosis, and malaria.

The Global Fund’s Board meeting in July, unable to mobilise more money, approved the machinery of retreat dressed as reform. This includes a policy allowing countries to purchase through the Global Fund’s  platform – as a  bridge-financing facility for nations “moving toward self-reliance.”

There is also a schedule under which 61 programmes across 35 countries will lose Global Fund support in the current three-year cycle, against only 21 entering. 

The Board was disarmingly candid about the direction of travel—what is new, it said, is the scale and pace of transition it is now driving. The honesty is welcome. The euphemism is not. 

“Self-reliance” is the term of art for a donor withdrawal that recipient countries did not choose and, in many cases, cannot yet absorb.

A year of American-led demolition

The United States accounted for the largest drop in development assistance for healthv in 2025, but it was not alone in slashing funding.

The backdrop is a year of American-led demolition. The Fund’s 8th replenishment closed in February at US$12.64 billion, well short of the US$18 billion it had sought, as France cut its contribution and the European Union delayed its pledge.

WHO, whose US withdrawal took formal effect in January, still faces a  $420 million gap across its 2025–2027 base budget – even after already shedding nearly a quarter of its workforce—some 2,507 posts—as of March 2026.

That’s not including a $553 million deficit in the Emergencies budget, funded separately through donor appeals. The world’s normative health authority is hollowed out at precisely the moment its authority is most needed. None of this is incidental to the week’s events; it is the gravitational hole into which every global health decision is getting sucked. 

Level of projected financing for the WHO’s base programmes segment of the proposed programme budget 2026–2027, US$ million.

It would be too easy, though, to treat country ownership as merely a cover story. Dependence on a handful of Western capitals was always a fragility rather than a virtue, and a system in which a single election in Washington can imperil HIV treatment for millions was never sound.

The ambition to build financing on domestic revenue and boosting regional institutions—Africa CDC foremost among them—is the right one, and some of the Global Fund’s stated shifts, such as concentrating resources on the poorest, highest-burden countries, are genuinely progressive. The quarrel is not with the destination but with the sequencing and the candour. 

Transition dictated by the rhythm of donor budgets rather than the readiness of national systems is not empowerment; it is abandonment with better branding.

Retreat in real time visible in DRC

Frontline Ebola responders in Ituri walked off the job last week over unpaid wages. Surveillance teams, security staff, community mobilisers and burial teams are among those striking.

What that retreat looks like in real time was visible this week in eastern Democratic Republic of  Congo. The Bundibugyo Ebola outbreak reached 2073 confirmed cases and 796 deaths by 14 July, a case-fatality rate near 37% and the fastest-growing the continent has recorded. 

WHO conceded that roughly 80% of new cases fall outside its contact tracing lists, and its emergency operation offered no comfort: it was not catching up in the race. Among the causes are funding gaps and unpaid, striking health workers. 

In Sudan, meanwhile, cholera has returned to Darfur and Kordofan with 1,330 cases and a case-fatality rate of 13.7%—a figure that testifies to how little care is reaching the sick. These are not abstractions about budget lines. They are fires being fought with fewer hands, and the arithmetic of the ledger is being written in mortality.

Two competing models in global health diplomacy

Cheers erupt as the World Health Assembly adopts the Pandemic Agreement, 20 May 2025. Over a year later, the treaty has yet to come into force.

The same underlying contest runs through global health diplomacy. The seventh meeting of the Intergovernmental Working Group on the WHO Pandemic Agreement, held in July, again failed to resolve the Pathogen Access and Benefit-Sharing system—the treaty’s unfinished heart. 

Two competing models remain on the table, and the dispute is, at bottom, about power: whether countries that supply pathogen samples are guaranteed the vaccines and therapeutics those samples yield or, once again, they are asked to furnish the raw material of global security while queuing for the products. Covid answered that question in practice, and the answer was not an equitable one.

A year after the Pandemic Agreement was adopted with considerable self-congratulation in 2025, its central bargain remains unsettled. A treaty without PABS is an empty handshake, however brave the smile that accompanies it. 

Austerity and opacity are often travel companions  

From 2024 to 2025, development banks and the Gates Foundation maintained their funds for health development assistance, but agencies such as the World Health Organization experienced large losses, according to Think Global Health statistics data.

Beneath the headline crises, the global health machinery continues to reshuffle with little scrutiny.

Unitaid is conducting a closed leadership search amid budget cuts. The Global Fund’s own hunt for an executive director continues, accompanied by pointed but ultimately vain calls for Germany to fill the vacuum Washington has left.

WHO, even as it cuts, has not been able to respond convincingly to the criticism that it continues to rely heavily on an unreported shadow workforce of consultants, which is almost as large as the remaining hollowed-out workforce of staff.  

This is a reminder that austerity and opacity often travel together, and that those urging discipline on others owe the same transparency in return. In a leaner system, the questions of who governs, and how openly, will matter more than they did in a flush one. The next Director General of WHO, the election process for which is beginning to lumber forward, should note.  

Global Health Leaders Urge Fewer Agencies Amid Funding Crisis

There is a defensible take on this moment, and intellectual honesty requires stating it. Leaner institutions can be more focused; co-financing can deepen national commitment; even a brutal shock can force overdue reform that comfort would have deferred indefinitely. 

But reform under fiscal duress has a habit of protecting the powerful and exposing the vulnerable, and the test of this transition will not be the elegance of the strategy documents. It will be whether a child in Ituri, or a cholera patient in Kordofan, is more or less likely to be reached next year than last.

The throughline of the week is a system negotiating its own contraction while insisting the contraction is a strategy. Some of it may yet prove to be. But the honest verdict on “self-reliance” will not be found in a board communiqué or a replenishment total. It will be found in the outbreak data—and this week, in eastern Congo and Sudan, those data were not reassuring.

About the Author

Mukesh Kapila is professor emeritus of global health and humanitarian affairs at the University of Manchester, and a board member of Health Policy Watch.  The opinions expressed are solely those of the author. 

Image Credits: Alexis Huguet/MSF, Guilhem Vellut via flickr, DRC Department of Health.

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