Chile implemented bans on the advertising of ultra-processed food during child-focused TV and digital media, at cinemas and in locations that attract a high proportion of children.

Ultra-processed products are usurping healthier, minimally processed foods in much of the world. Breakfasts are too often pre-packaged and sugar-laden, while lunches are loaded with sodium and wrapped in plastic – products that have been transformed using industrial processes and filled with additives to make them highly palatable.

The widespread consumption of these foods and drinks, high in salt, sugar and saturated fat, is responsible for an estimated 11 million preventable deaths each year.

Intense, pervasive marketing by food and beverage companies is central to profit-driven strategies to increase the intake of ultra-processed foods, and children are the most vulnerable targets. While multiple countries have implemented strategies to thwart the food industry, including marketing restrictions, warning labels and taxes, Chile’s comprehensive approach to food policy stands out.

 Chile passed legislation in 2016 that went a step beyond the incremental, single-issue food policies seen globally, such as front-of-package labeling or sugary drink taxes. Chile’s law combines these approaches with exacting restrictions on marketing unhealthy foods and beverages to children and banning the sales of these products in schools. 

Chile’s comprehensive law covers not only what children are eating and drinking, but how they are exposed to ultra-processed products through all forms of media.

These policies have clearly moved the needle in the fight against the harms inflicted by ultra-processed foods and drinks on children in Chile. The world would be wise to learn from Chile’s example.

 Sweeping food policy reforms

In 2016, close to half of all children in Chile were overweight or obese. That same year, Chile passed food policy reforms under one sweeping new law.

 The Law of Food Labeling and Advertising addresses unhealthy diets in three ways. First, it mandates black, octagonal warning labels on products high in sugar, calories, sodium and/ or saturated fat.

Secondly, it bans the advertising of these products during child-focused TV and digital media, at cinemas and in locations that attract a high proportion of children. Sponsorships are also banned.

Thirdly, food and beverage companies are prohibited from intentionally using child-directed advertising methods, such as cartoon characters or mascots (for example, Tony the Tiger is no longer a visible Frosted Flakes mascot).

In 2018, a total TV advertising blackout on unhealthy products between 6 am and 10 pm was put in place. Finally, the government banned the sale or free distribution of ultra-processed products at schools and nurseries.

Chile’s front-of-package warning labels alert consumers to high levels of sugar, salt and saturated fat, as well as calories, following the implementation of the Law of Food Labeling and Advertising.

 Crucially, the bill required the Ministry of Health to implement the new regulations within a year and created strict penalties for violators. The stringent nutrient thresholds were phased in over a three-year period as a minor concession to food companies

 Seven years after Chile’s policies were first adopted, there is a growing body of evidence that they have worked as intended. The law provides proof-of-concept for comprehensive global healthy food policies and offers a path forward for public health advocates grappling with the increase in ultra-processed food consumption and associated health harms.

The numbers don’t lie

 To date, only a handful of prospective studies have examined the association between comprehensive food policies and a lessened burden of obesity and disease, especially in children. While it takes time to see changes in obesity rates, very few existing policies have been associated with significant impacts on diets or industry behavior due to either falling short of Chile’s wide-ranging approach or weak enforcement mechanisms.

 But when a law is as airtight as Chile’s and rigorously upheld, it’s possible to assess the short-term results of implementation. This allows researchers and advocates to reasonably extrapolate how this suite of policies will save lives and prove cost-effective.

New research published in the International Journal of Behavioral Nutrition and Physical Activity by researchers from the University of North Carolina, the University of Chile and Diego Portales University found that the Chilean law has significantly reduced children’s exposure to unhealthy food marketing.

Since the law went into effect in 2016, there has been a 73% drop in Chilean children’s exposure to TV ads for regulated foods and drinks. In addition, TV advertising for unhealthy foods and drinks had dropped 64% by 2019, and the number of TV ads for unhealthy foods and drinks that used prohibited child-directed content (such as cartoon characters) dropped 67% in the same period.

 

Chile’s marketing restrictions mandated the removal of cartoon characters on food and beverages aimed at children. 

These findings add to a growing evidence base demonstrating a steep overall decline in Chileans’ purchases of foods containing “nutrients of concern” in response to the 2016 law, according to a 2021 study in The Lancet.

The considerable decline seen after 2016 was greater than those following earlier laws in Chile solely focused on sugary drink consumption. Across the country, overall calories purchased declined by 3.5%, purchased sugar declined by 10.2%, saturated fat declined by 3.9% and the sodium content of overall purchases declined by 4.7%.

Crucially, the decline in unhealthy food purchases was even more pronounced for the unhealthiest products highest in nutrients of concern. Additional research also observed important decreases in the nutrients themselves (i.e., sugar and sodium) in packaged foods as the industry began to reformulate products to comply with the new policies in Chile.

The challenge of changing media landscape

While the effectiveness of marketing restrictions has been demonstrated in Chile, especially when implemented in tandem with clear front-of-package warning labels and sugary drinks taxes, it is early days and there are still challenges to overcome.

 Time-phased restrictions on TV and traditional direct-to-consumer advertising have been successful at reducing children’s exposure, but these policies must be able to reach all forms of media that children encounter – a challenging proposition in our quickly transforming media landscape.

Regulations need to consider how often children watch television outside of “child-directed” programming. The recent WHO guideline on policies to protect children from the harmful impact of food marketing notes the importance of moving beyond limiting marketing on the very narrow subset of television directed at children to all channels that children may view.

While it may seem like a small language change, moving beyond only regulating marketing on shows for children would be a meaningful, more comprehensive next step for these policies.

Advocates and many policymakers also understand the need to address the huge growth in food marketing across digital and social media platforms. Industry won’t go away quietly, particularly as visible consequences for violating government policies are handed down. 

Child-directed ads have already adapted and migrated to video games and platforms like TikTok, YouTube and Twitter. Although Chile’s regulation policies cover digital media, the term “child-directed” only covers a small portion of what children see online, particularly when it comes to social media.

 Future marketing restrictions may benefit from scrutinizing existing legislation restricting other industries from influencing young people, such as tobacco. The industry playbook is recycled, repackaged and rarely changes. Public health experts and policymakers can avoid being overrun by the same schemes by being proactive and learning from efforts in other industries.

Public health policymaking should be led by public health experts and governments, not muddied by commercial interests. Where we’ve seen similar policies in other countries that allow industry to dictate and enforce their own marketing regulations, the result has been weakened policy and inferior evidence of efficacy.

Following in Chile’s footsteps, other governments need to continue this momentum and implement effective policies based on evidence-informed regulations with clear penalties to confront the challenges ahead.

Francesca R Dillman Carpentier, PhD, is the W. Horace Carter Distinguished Professor at the Hussman School of Journalism and Media at the University of North Carolina, Chapel Hill, US. She conducts research on mass media effects, the psychology of media audiences, and the analysis of media content.

Lindsey Smith Taillie, PhD, is an associate professor in the Department of Nutrition at the Gillings School of Global Public Health at the University of North Carolina, Chapel Hill. She is a nutrition epidemiologist focused on designing and evaluating healthy food policies.

Teresa Correa, PhD, is a full professor in the School of Communication at Diego Portales University, Chile, director of the Research Center in Communication, Literature and Social Observation (CICLOS) and alternate director of the Millennium Nucleus on Digital Inequalities and Opportunities (NUDOS in Spanish). She conducts research on media and inequality, particularly in the digital sphere.

 

Image Credits: UNC Chapel Hill.

One sample of Cold Out cough syrup was found to have unacceptable amount of DEG, as per WHO alert.

Adding to the spate of contaminated medicines linked back to India, the World Health Organization (WHO) has flagged another cough syrup for the presence of contaminants. 

This is the fifth medical product alert for an Indian formulation issued by the WHO since October 2022. 

“A sample of the Cold Out Syrup was obtained from one location in Iraq and submitted for laboratory analysis. The sample was found to contain unacceptable amounts of diethylene glycol (0.25%) and ethylene glycol (2.1%) as contaminants,” the WHO medical product alert issued on 7 August said. The acceptable amounts of both substances in cough syrups is up to 0.10%. 

The syrup is generally used in Iraq to treat and relieve symptoms of common cold and allergy. The WHO tested a sample from a specific batch of the syrup after it received a report on 10 July about possible contamination. The cough syrup was manufactured by Fourrts  Laboratories (India), on behalf of another Indian company, Dabilife Pharma, the WHO added. 

Since October 2022, the WHO has issued four medical product alerts concerning at least eight liquid medical formulations manufactured in India. In October 2022, the WHO reported that at least 66 children in the Gambia died after consuming cough syrups manufactured in India. 

Most recently, WHO’s Africa region reported that cough syrup laced with high amounts of Diethylene glycol (DEG) – as much as 28.6% – were found in samples of NATURCOLD sold in Cameroon.

While the product alert stated that the agency is unclear about the real manufacturer of the product, Reimann Labs, an Indian pharmaceutical company that was allegedly the manufacturer of the tainted product found in Cameroon, was ordered to shut down production by the Indian drug regulators. 

When cough syrup is manufactured, it needs a solvent to dissolve all its active ingredients, add sweetness, and act as a lubricant. Either glycerine or propylene glycol are usually used, with Glycerine Indian Pharmacopoeia (IP) the grade used in drugs and medicines. 

The cheaper industrial glycerine, which can contain DEG and ethylene glycol, is supposed to be used only in chemicals and cosmetics, according to the good manufacturing practice framed by the WHO. 

While many generic medicines are made in India, the country generally lacks the capacity to conduct rigorous checking of much of the medicine that is produced.

Image Credits: WHO.

A woman prepares for an HIV test in Uganda.

Most of the $500 million in US support for Uganda’s HIV/AIDS epidemic, financed by the US President’s Emergency Plan for AIDS Relief (PEPFAR), is likely to go ahead next month despite the country’s draconian new Anti-Homosexuality Act, according to sources close to the process.

However, it is still possible that some parts of the PEPFAR grant being delivered by the Ugandan Health Ministry may be re-assigned to other implementing partners. 

Health and human rights activists have been pressurising PEPFAR to re-route four particular contracts designated for the Ministry of Health to groups that will uphold LGBTQ rights, describing Health Minister Dr Jane Aceng as  “a key proponent” of the AHA.

The future of Uganda’s PEPFAR grant has been in limbo since April when US officials called off a meeting to discuss the Country Operational Plan for 2023 (COP23) because of the draconian Act, which was passed in March . The AHA  includes the death penalty for “aggravated homosexuality”, prison sentences for gay minors and fines for people offering services to LGBTQ people, including landlords and lawyers.

Uganda’s Health Minister, Jane Ruth Aceng

US continues to ‘evaluate actions’ 

While neither confirming nor denying that the PEPFAR grant would go ahead, a spokesperson for the US National Security Council told Health Policy Watch that, “as directed by President Biden, the US government will continue to evaluate additional actions to promote accountability for Ugandan officials and other individuals responsible for, or complicit in, undermining the democratic process in Uganda, abusing human rights, including those of LGBTQI+ persons, or engaging in corrupt practices”. 

“As the President said in May, we will continue to reassess on an ongoing basis the impacts Uganda’s Anti-Homosexuality Act (AHA) may have on our ability to safely deliver services under PEPFAR and other forms of assistance and investments, which is meant to benefit all Ugandans,” according to the NSC spokesperson.

“HIV remains a serious threat to global health and economic development, and thus the focus of any support the United States provides through PEPFAR is intended to continue saving lives among all communities without discrimination, including in Uganda.” 

Visa travel sanctions have been imposed on some Ugandan politicians in the wake of the AHA.

Uganda’s PEPFAR dependence

Over 90% of Ugandans living with HIV are reliant on PEPFAR-sponsored antiretroviral treatment – 1.3 million of the 1.4 million on treatment, according to UNAIDS figures.

Treatment interruptions for them would have serious consequences for their health and for the country’s fight against HIV and AIDS.

But one of the cornerstones of PEPFAR’s approach to combatting HIV globally is targetting “key populations” who are most vulnerable to HIV – including men who have sex with men (referred to as such as many do not identify as gay, particularly in countries where they would face persecution if they did).

Shortly after the AHA was passed, PEPFAR head Ambassador John Nkengasong wrote to all parties involved in the Uganda COP process – government and civil society organisations – announcing the postponement of a meeting intended to authorise the plan.

“This postponement will allow us more time to collectively and effectively assess the legal and programmatic implications of the evolving legislation and broader environment in Uganda, which impacts PEPFAR-supported HIV/AIDS programs, and make relevant adjustments in order to resolve COP23 plans as appropriate,” Nkengasong explained.

In June, Dr Henry Mwebesa, Uganda’s Director General of Health, sent a letter to all health facilities urging them to deliver health services without discrimination, and to respect patients’ confidentiality and safety.

His letter was copied to all UN agencies, PEPFAR, the World Bank, the Global Fund and other agencies that provide aid to the country.

UN Human Rights office closed

However, despite the threat of international sanctions, Uganda further alienated itself from the human rights community by refusing to allow the UN  Human Rights Commission to continue to operate in the country.

Expressing “deep regret” at the closure of his offices over the past weekend after 18 years of operations, UN High Commissioner for Human Rights Volker Türk warned that “serious human rights challenges remain in the path to full enjoyment of human rights for all”.

 

Türk has been an outspoken critic of AHA, describing the Act as “probably among the worst of its kind in the world”.

In his statement last Friday, Türk expressed particular concern about the human rights situation in Uganda ahead of the 2026 elections, given the increasingly hostile environment in which human rights defenders, civil society actors and journalists are operating.

He noted that most of the 54 NGOs that were arbitrarily suspended in August 2021 remain closed and warned against retrogression from Uganda’s commitments under the international human rights treaties it has ratified, including in the passage of the “deeply discriminatory and harmful anti-homosexuality law, that is already having a negative impact on Ugandans”.

Unusual move by US Ambassador to Uganda

In an unusual move, Natalie Brown, the US Ambassador to Uganda, addressed the International AIDS Conference in Australia last month about the impact of the AHA.

Brown and Dr Vamsi Vasireddy of the US Department of Defense Walter Reed Army Institute of Research in Uganda presented a late-breaking abstract reporting that the “hostile environment created with the passing of AHA and the fear of law enforcement has led to reduced access to key population (KP)-friendly services”.PEPFAR supports over 50 drop-in-centers (DIC) that provide HIV prevention and treatment services focusing on KP clients.

“Punitive laws against KP have the potential to derail HIV epidemic control,” warned Brown and Vasireddy.

To mitigate against this, PEPFAR has started the home delivery of anti-retroviral therapy (ART), condoms and Pre-Exposure Prophylaxis (PrEP) and multi-month dispensing.

It has also employed paralegals to offer legal support for KP clients, and introduced greater security at drop-in centres, including biometric access and locked cabinets for client files.

Since the Act was introduced, there has been an increase in attacks on people perceived to be LGBTQ,

Image Credits: 2011, Sokomoto Photography for International AIDS Vaccine Initiative (IAVI).

Bloomberg
Kelly Henning speaks at the Seventy-sixth World Health Assembly Event in Geneva, Switzerland, on Saturday, May 20, 2023. (Photo by Stefan Wermuth)

Some 300 million people have been protected from becoming smokers in the 15 years since WHO launched the ‘MPOWER’ package of recommended policies for reducing smoking prevalence in countries worldwide, declared Kelly Henning, of Bloomberg Philanthropies, at a press conference in Geneva this week

She was speaking at a WHO briefing launching the 2023 WHO report on global tobacco control

Bloomberg, a funder of the original MPOWER policy package and its continuing implementation, has been WHO’s leading partner in the massive tobacco control initiative.  

And Henning, head of health at Bloomberg for just as long, has been the key figure in the journey, forging this and key collaborations with the global health agency on a range of preventative health initiatives – including for healthier cities and diets, road safety, and drowning prevention. 

A former director of epidemiology in New York City’s Department of Health, Henning was the first and, so far, only head of public health at the Philanthropies since the programme’s inception. 

As such, she has shaped the collaborations with WHO, with a practical and laser-focused vision on what gaps and needs the Philanthropies can realistically address. 

Prior to the new tobacco control report’s launch, Health Policy Watch Editor Elaine Ruth Fletcher, sat down with Henning, a medical doctor and epidemiologist, to hear more about the ongoing work, and future priorities. 

Elaine Fletcher: Refreshing briefly, the things that Bloomberg has been focusing on since the inception of the health programme in 2007, have been obesity, tobacco control, road safety, drowning prevention. Is there anything else? 

Kelly Henning: Cardiovascular health. And we also have a large, what we call, ‘Data for Health’ programme, which is really about strengthening birth and death registration, and also the use of data. And, we do that collaboratively with Ministries of Health. 

We also have Mike Bloomberg [founder of Bloomberg Philanthropies] as the global ambassador for NCDs and injuries in the WHO. So since that started, we started the Partnership for Healthy Cities. 

EF: Can you talk about the successes you’ve seen with your work until now? And how do you envision going forward?

KH: In our portfolio on non communicable diseases and injury prevention, we have a big focus on policy change. And one of the reasons that we do that is because we think of it as a sustainable set of interventions. 

Sure, we want to work on assisting governments. But first, you have to have those baseline policies that are ‘best practice’ in place. 

And this has been very true in our tobacco control programme, in our road safety programme, in our food policy programme, involving ‘smoke free air’ actions, bills that raise tobacco taxes, bills that raise sugary beverage taxes, bills that require helmets for motorcycle use. 

These things are durable so that once they’re in place, they sort of take on a life of their own,  and they can be built upon over time. I think that’s a sort of principle of how the public health team works. And we do think that our issue areas do overlap with many of the issues of our time. 

“For example, I think we now know very clearly that a healthy population is critical to addressing a new viral threat. And how do you assure a healthy environment? Well, you know, you want to reduce tobacco use, you want to make sure that cardiovascular risk factors are addressed, and healthy food is very important for overall health. So we touch upon those more contemporary issues through some of the work that we’ve already done, and some of the work that we’ll be continuing to do. Similarly, there was a very major gap in mortality data during the pandemic. And so we think that our “Data for Health” programme, which is really seeing some increasing momentum now, post pandemic, is likely to have a positive impact on that. 

EF: Do you envision continuing those strands pretty much as they are those themes or do you envision adding to them or changing them? 

KH: Each time that we have reinvested in one of the topic areas where we work, we evaluate what we’ve done thus far and look for critical gaps. So for example, in tobacco control, we now see that many countries have at least one best practice tobacco policy in place and an increasing number [of countries] have multiple best practices in place like marketing bans, on-pack warnings and taxes. 

So now we’re adding smoking cessation as a focus area in that programme. Because as those policies are in place, it pushes people to quit. And, so they are increasingly asking for help in quitting. That’s an example of how each time we evaluate where we are on the trajectory of the work and then we add things that might be relevant as we go along. 

Another thing that we’re doing is we’re thinking more and more about the workforce and trying to invoke young public health leaders because it’s very important that country-based experts be developed and be able to take on new work all the time. So in all of our various initiatives, we’re engaging with public health leaders, young public health leaders. 

EF: Let’s talk about tobacco control. What would you see as outstanding examples? And are higher income countries typically stronger with respect to tobacco control?  

KH: No, not always.

EF: Okay, So, please provide some good examples. 

KH: Every other year, WHO puts out the Global Tobacco Control Report. It looks, country by country, at how countries are doing, and policy by policy across the MPOWER package. Based on WHO’s latest expert review, there are now four countries in the world that have best-in-class policies around the key indicators for tobacco control: smoke free public places, marketing bands, pack warnings, mass media campaigns and [tobacco] taxes. And those are Brazil, Türkiye and now Mauritius and The Netherlands.

The  other encouraging key message here is that the number of countries with two or more MPOWER policies is going up every year. So we’re seeing more and more countries are progressing on tobacco control, which is great.

Proportion of world’s population covered by at least one fully-implemented MPOWER policy.

EF: In terms of obesity and healthy foods, the WHO recently updated it’s  ‘Best Buys’ to prevent diet-related NCDs, with a broader set of recommended policies on the taxation and regulation of  “unhealthy foods”. These relate not only to salt, but also to sugar, trans-fats and, as a result, to ultra-processed foods. Can you explain what this means?  

KH: We think that the WHO guidance documents and best buys are really important for our work, because countries obviously are paying very close attention to what WHO is putting out and they strengthen our ability to advocate for best practices and to push forward. 

In food policy, there’s still a lot of room to evaluate various strategies to see which ones are most impactful or what combination of strategies is most impactful? We have that evidence from tobacco control. In food policy, we’re still gaining evidence and so when WHO puts out expanded recommendations that help us engage with countries to do more, and then we also fund the evaluation pieces so that we can see what kind of impact these policies are having on diet, consumption, etc.

The Supplemental Nutrition Assistance Programme reaches 38 million people in the United States every year. It is the largest anti-hunger programme in the country.

EF: Along with limiting unhealthy foods, can you speak about good practice examples of national policies to encourage healthier foods, such as fresh fruits and vegetables?  

KH: Many countries are doing that. For example, a number of low- and middle-income countries are improving their school food and public food policies to encourage and include more fruits and vegetables. Discussions around taxing foods with low nutrient value, foods with high sugar etc., are also bringing on board the idea of incentives for [fresh] fruits and vegetables. There’s a long way to go in this space, but it’s certainly something that’s really bubbling up as an area of major interest.

E: Can you just talk about one or two lower middle income countries that have picked up on this?

KH: Brazil has phenomenally good school food policies and they have done a lot of work in the space and are really a model for some of the thinking around school and public foods. Higher income countries are looking at that even now. The US is starting to talk about how to handle the Supplemental Nutrition Assistance Programme (SNAP) for example, which is the supplemental food programme for lower income persons in the United States. So, I think higher income countries are learning from some of these low- and middle-income country examples as well. 

EF: The US SNAP programme, at the moment, it’s neutral about the nutrient quality of foods? 

KH: It has some restrictions, but they’re pretty minimal.

Road traffic fatalities by regional classifications of the World Bank, adjusted for underreporting, 1990–2020.

EF: When it comes to traffic injuries, it seems that the emphasis is still mainly on road safety, rather than transport management to support more sustainable public transport, walking and cycling. Has there been any thinking about urging WHO to look at how public transport modes perform, in different countries, in terms of traffic injury.   Typically in high income countries bus and rail modes are safer, but this may not be true at all in lower-income countries. However, none of these issues are picked up right now in the current data collection, which looks at injuries purely in terms of  road vehicles and vehicle types, not modes of travel. 

KH: So, as you know, WHO puts out a road traffic safety report periodically. They have one coming out again in November of this year. And it’s again a country by country assessment of deaths due to bus, due to cars, due to trucks, that’s in each country. Public versus private is not there as far as I’m aware. But I think the important point here is that the largest proportion of road crash deaths are pedestrians. Pedestrians and motorcyclists and bicyclists – vulnerable road users, are the largest proportion, and so that’s the group that I think needs focus.

EF: That’s exactly my point is that if you have an overcrowded road system, no matter how good it is, you’re always going to have pedestrians marginalized.  But you’re not going to get that story data wise [in the World Traffic Report].

KH: So we definitely advocate for public transport. There’s no question about that in the Road Safety Programme. And public transport, as you know, is not always safe. So for example, in Türkiye and Mexico City, we’ve had experiences where the passengers from the bus might get off the bus right into traffic. So, addressing those things are all part of what we have advocated for in the Bloomberg supported Road Safety Programme. WHO is a partner in that as well. 

I think there’s always going to be more than we can do. I think that report is our best global snapshot at the moment and didn’t exist previously. So it’s wonderful that it exists but improvements in those reports are a continuing process for sure.  

EF: In terms of the traffic injury, apart from that particular observation, what do you see as the biggest success stories? 

KH: The Bloomberg Initiative on Road Safety has a two-part approach. One is to improve national legislation for best practice laws to reduce road crash deaths. And the other is to prove that it’s possible to do those things at a local level, at the city level. In the 28 cities that participate in the initiative, a number of those cities have done very good work, and have shown declines in road crashes.

A traffic jam in Mumbai, India.

EF: Can you provide some good practice examples here, as well?  

KH: Mexico City has always been very engaged. Mumbai [India] is another location that has done a lot of local level work showing improvement. So some of that is infrastructure, things like speed bumps, or re-organizing intersections so that pedestrians have the opportunity and time to cross. 

EF: When you talk about pedestrian sidewalk continuity, or ease of crossing, you have to talk about infrastructure investment. How does Bloomberg encourage that kind of investment?

KH: That’s why we work at city level on those pieces so that we can work directly with the mayor’s office. Because it really does involve engagement with the city and the city government more broadly, with their Transportation Department, their Infrastructure Department. Those are the bodies that we work with, using primarily local funds, to get those things done. They can be quite inexpensive. So we provide technical assistance through our partners, which include the World Resources Institute (WRI) and  NACTO (National Association of City Transportation Officials) there. We have partners that work in that space that work with the cities directly.

EF: As a philanthropy, how do you move the needle? You mentioned your work with partners is key; can you tell us a little bit more about your partnerships strategy? 

KH: So all of our initiatives are really partnerships. We have a group of partners with competitive advantages in various aspects. For example, in tobacco control, WHO is a partner, Vital Strategies is an implementation partner, Campaign for Tobacco Free Kids is a partner that does advocacy work, US CDC works on data collection, as well. Those partners in turn re-grant or provide technical assistance at the country level. That allows us to have much larger reach. Almost all of our programmes have small grant projects, so countries, or groups and countries, can apply for resources to assist in projects that relate to those initiatives. Again, that allows us to have much greater reach than we would have otherwise. 

Map of cities around the world participating in the Partnership for Healthy Cities under the Bloomberg Philanthropies umbrell. Image: Bloomberg

EF: The Partnership for Healthy Cities has been another important foundation of your recent work – with both cities and WHO. But for some time, there seemed to be hesitation about including air quality interventions into that programme, which was more focused on traffic injury, healthy diets, and other classical areas of Bloomberg engagement in urban health. Has that changed at all?  

KH: Air pollution is on the list. But it’s really about data collection through air sensors and helping the city use low- cost air quality sensors to help guide their city policy. So that’s a new array and several cities have taken that up. Beyond that, we have a team that focuses just on the environment, and our environment team also works on air pollution. 

EF: In the wake of the pandemic, there has been much more talk about fostering more sustainable and healthy food systems – that curb ecosystem destruction and concurrent disease risks, associated with industrialized agriculture. Is this on your radar?  

KH: We don’t have much focus on agriculture right now. Although I think if we do have, the only way that we really bump up against agricultural practices is that the tobacco industry will often use tobacco growing as in certain countries as a key reason why tobacco control cannot be done and that is not correct. There’s a little piece of that. But not in terms of a larger agricultural policy right now.

EF: Any other under-represented topics you’d like to address? 

KH: I just want to say something about drowning prevention because it’s under-appreciated.

Even in the US, among children under five, after the neonatal period, drowning is the leading cause of death. So we’re very excited about our work in this space. We’ve been working in Bangladesh for a long time in those communities there. We’ve seen reductions of 85% of drowning deaths among children under five. 

EF: What is the major thrust of prevention here? 

KH: In Bangladesh it is very young children. So it’s about community daycare. During the hours of 9 a.m.-1 p.m., when the mothers are in the fields or otherwise occupied, there’s a mother who watches young children. It is about supervision. And it has had enormous impact. 

In Vietnam, the peak age [for drowning] was more school aged children. So there, we are partnering with the government to implement school based swimming lessons, survival swimming lessons. And now we’re looking at a couple of countries in Sub-Saharan Africa where there’s a lot of work to do in this space. We’re very excited about it.

EF: Looking forward, what would you like to see out of the rest of this year’s health calendar?

KH: I would love to see a continued emphasis on noncommunicable diseases. we can’t lose sight of the fact that we have to continue to work in this space. Premature death from non communicable diseases is important and it’s going to rise. We know that there’s the next high level meeting on non communicable diseases coming up at the UN General Assembly in 2025. So the more that we can do to mobilize heads of state and these ministers around this issue, the better.

Megha Kaveri contributed editing to this story. 

Image Credits: WHO, WHO , USDA.

Barely over a quarter of babies in North America are exclusively breastfed for the first six months of life – far lower than anywhere else in the world.

The US has yet to sign the International Code on Marketing Breast-Milk Substitutes, adopted by the World Health Organization (WHO) in 1981 to curb the aggressive marketing of formula milk, while its maternity leave benefits also lag behind many other countries.

The global rate for exclusive breastfeeding is now 48% – just 2% short of the 2025 target set by the World Health Assembly.

“South Asian countries have the highest exclusive breastfeeding rates at 61% followed by East and Southern Africa with the second highest birth rate at 55%,” UNICEF’s Fatmata Fatima Sesay told a media briefing on Thursday to mark Breastfeeding week.

“Almost one in three infants in the Middle East and North Africa are exclusively breastfed and only 26% in North America are exclusively breastfed, so we really need to close disparities and gaps,” added Sesay, who is the agency’s breastfeeding lead.

“We have seen that 21 countries have increased their exclusive breastfeeding by at least 10%. Countries as diverse as Cote d’Ivoire, Marshall Islands, the Philippines, Somalia and Vietnam have achieved large increases in breastfeeding rates, showing that progress is possible when breastfeeding is promoted, protected and supported.”

The WHO and UNICEF advocate for babies to be breastfed within an hour of birth, exclusive breastfeeding – nothing but breastmilk – for the first six months of their lives, with breastfeeding continuing until the age of two.

Restrictive working conditions

However, many women struggle to reach these targets because their working conditions do not allow this.

Dr Victor Aguayo, UNICEF’s global director of nutrition and child development, called on all stakeholders to provide three important measures to encourage breastfeeding, which is fa better for a baby’s health and development than formula milk. 

“The first one is to ensure a supportive breastfeeding environment for all working women. This includes access to lactation breaks and facilities that enable women to breastfeed their babies once they return to the workplace,” said Aguayo.

“The second one is to provide sufficient paid leave to all working parents to meet the feeding needs of their young children. This includes paid maternity leave for a minimum of 18 to 24 weeks or more after birth,” he added.

“And the third one is increased investments in breastfeeding support including national policies and programmes that regulate and promote public and private sector support to breastfeeding women in the workplace.”

The International Labour Organization’s (ILO) senior Gender Specialist, Emanuela Pozzan, noted that 649 million women lack adequate maternity protection.

“We see that paternity leave laws are on the rise,” she added. “We have 115 countries that provide paternity leave – 33 more countries compared to 2011. So the trend is positive, and yet 1.26 billion men live in countries that do not provide paternity leave.”

While 68 countries have parental leave, this was only paid in 46 countries.

‘The ILO’s Convention 183 on maternity protection says women workers should be provided with the right to one or more daily nursing breaks or a daily reduction of working hours, which should be counted as working time and remunerated accordingly,” she added. 

“In 138 countries there is the provision of statutory rights to time and income security for breastfeeding. Eighty  countries grant two daily nursing breaks, and 199 countries offer the right to daily nursing breaks for six months.”

Only one in 10 potential parents have access to free and affordable childcare services. And in fact, 21 out of 178 countries grant universal childcare services in the laws for children aged zero to two years.

Image Credits: WHO.

The presence of Hungary’s President, Katalin Novak (second from right) as a speaker at the Women Deliver conference, shocked many SRHR advocates.

The Women Deliver conference is one of the world’s largest gatherings on gender equity and sexual and reproductive health and rights (SRHR). This year, amidst a global backlash against the rights of women and people of diverse genders, the meeting was held for the first time in Africa in Rwanda from 17-20 July.  More than 6,300 women’s rights activists, feminists, and policymakers from 170 countries attended.

There were significant outcomes. Most notable was Canada’s commitment of more than $200 million in funding for new projects to support sexual health and reproductive areas, including family planning, comprehensive sexuality education, advocacy for SRHR, safe abortion and post-abortion care, and sexual and gender-based violence. There was also a timely boost for resourcing feminist movements and growing collective political influence from the local to multilateral spaces. 

Closing the gender nutrition gap

A monumental campaign, Closing the Gender Nutrition Gap: an Action Agenda for Women and Girls, was launched by over 40 organizations to close the gender nutrition gap. Women and girls worldwide are twice as likely to suffer from malnutrition as men and boys. 

This campaign is an excellent opportunity for feminist movements to highlight the stark – and growing – inequalities in nutrition. Cultural norms, social roles, economic disparities, and discriminatory practices create and sustain this overlooked crisis. 

‘Closing the Gender Nutrition Gap’ identifies four action areas.

The United Nations Population Fund (UNFPA) announced the Kigali Call to Action: United for Women and Girls’ Bodily Autonomy to accelerate investments and actions, with women-led organizations and the feminist movement at the center. UNFPA called for coordinated and collective action to achieve bodily autonomy, reproductive rights and gender equality for women and girls everywhere.

Increased attacks

The meeting came a year after the US Supreme Court struck down Roe v Wade, a key abortion rights law, which is still sending vibrations and bringing a lot of uncertainty about women’s reproductive rights beyond the US.  

In Africa, for the last few years, conservative leaders have been restricting space and policy around women’s bodily autonomy, donors have restricted funding, and there’s fear among civil society organizations advocating for reproductive justice, including abortion. 

There are intensified, well-organized attacks on the human rights of women and the LGBTQI+ community, especially in Africa. Women and LGBTQI+ people are becoming increasingly unprotected in many African countries as they are subjected to waves of well-funded efforts by anti-rights actors that endanger lives.

Family Watch International head Sharon Slater, a leading international opponent of sexual and reproductive health rights, on a visit to Uganda shortly before that country adopted its Anti-Homosexuality Act.

Well-organized anti-gender movements have been working to undermine women and LGBTQI+ communities rights for decades. This growing conservative, anti-gender narrative includes key influential policymakers, fundamentalist religious bodies, and even some “progressive” governments funding anti-LGBTQI+ backlash through bilateral relationships with religious civil society organizations, such as the Inter-Religious Council of Uganda. 

These groups have popularized support for discriminatory and retrogressive legislation in developing countries, such as the 2023 Anti-Homosexuality Act in Uganda, which made ‘aggravated homosexuality’ punishable by death. As a result, many Ugandans who identify as members of the LGBTQ+ community are now living in fear for their lives.

With the support of conservative civil society organizations that have access to major decision-making bodies, negotiations and forums, anti-rights entities from Africa and across the globe are co-opting human rights language and weakening or removing references to sexual and reproductive rights. 

Beyond financial backing, anti-rights and anti-gender actors have trained and helped representatives take over influential positions in governments, courts, and other institutions in many places to institutionalize anti-rights norms and practices in offices of influence.

Contradictions at Women Deliver

Many feminist activists had hoped this year’s meeting to be a crucial rallying point, but that high hope was very quickly shot down by the presence of key advocates against the very rights this conference is intended to promote. Specifically, the participation of Hungary’s rightwing president, Katalin Novak, who addressed the opening ceremony, shocked many feminists and advocates. 

As former Family Minister in the populist government of Viktor Orban, Novak has been a party to anti-LGBTQ laws and the tightening of abortion regulations in her country. Novak has also told women not to expect the same pay as men, while her government has outlawed adoption by unmarried couples and excluded LGBTQ couples from adopting children. Hungary has also refused to ratify the Istanbul Convention, designed to protect women from violence. 

Thousands protest against anti-LGBTQ laws in Budapest, Hungary, in 2021.

Much more to my discomfort was the number of people that applauded her speech in Kigali; whether it was about being in the presence of a  president or sharing the values communicated, they cared little for the symbolism that their applause meant for women and LGBTQI rights in Africa.

Her speech was dismissive of teenage pregnancies in many global south countries, which is an insult to a region grappling with rates as high as 25%, twice the global average at 92 births per 1000 women.  Her presence, and the opportunity given to her to speak, were not representative of the supposedly progressive audience gathered in support of all women in all their diversity and all their choices.

Novak also perpetuated harmful gender norms around women and their supposed reproductive responsibility to “choose motherhood”, while her appreciation for African women’s high birthing rates was concerning, especially with burdens associated with this, from high maternal deaths, high teenage pregnancy rates, high unmet need for contraceptives and gender-based violence in the form of forced unions, child marriages and restrictions on women’s bodily autonomy.

Reproductive autonomy includes the right to determine the number of children to have and the spacing of children, and that right can be to determine whether to have no children. The negative gender social norms we face in Africa and restrictive policies do not make this possible for many women.

Her remarks were racially degrading about African women’s “reproductive responsibility”. Several feminists, human rights activists and advocates have called out Women Deliver for giving an audience to Novak in a space that is supposed to be safe. 

Safe spaces and agency must be protected

We need to stay in control of our voice and demand accountability from entities that claim to be feminist at any point that they challenge the realization and enjoyment of our rights. Women Deliver, one of the largest gatherings on gender equality, should remain a place to challenge corrosive gender norms that sustain inequality and challenge restrictive, discriminatory, and oppressive norms.

Normalization is an instrument of power and plays a role in classification and hierarchization. In this case, platforms such as Women Deliver, normalizing anti-rights groups’ access to spaces of women and gender-diverse people to spread harmful rhetoric undermines their safety and their full humanity. Countering these anti-feminist, anti-democratic trends is everyone’s responsibility. 

Platforms such as Women Deliver should be safe spaces for women to dialogue and call to account, in all their diversity. There should be accountability for surrendering these spaces to anti-rights groups and advancing politics that endanger the progress and safety of gender-diverse people and women’s rights.

Yvonne Mpambara is a Ugandan feminist lawyer and Reproductive Justice Advocate. This article was first published by African Feminism.

Image Credits: Lydia Gall/ Human Rights Watch.

RSV
GSK has sued Pfizer for patent violations over its RSV vaccine

Merely months after securing US Food and Drug Administration (FDA) approval for its Respiratory Syncytial Virus (RSV) vaccine, British pharma giant GSK has taken Pfizer to court for patent violations. 

GSK filed the lawsuit in a US federal court in Delaware on Wednesday alleging that Pfizer’s RSV vaccine, Abrysvo, violates four patents surrounding the antigen that GSK uses in its own RSV vaccine, Arexvy, Reuters reported

The US FDA approved both vaccines in late May, to be administered to adults aged over 60 years. RSV is common during winter seasons and kills over 100,000 children aged under five every year. While its symptoms are considered non-threatening to adults, over 14,000 adults aged above 65 in the US die due to RSV every year. The virus is estimated to affect around 64 million people every year globally, with an annual death toll of 160,000. 

In response to the lawsuit, Pfizer asserted confidence in its intellectual property position and added that it will strongly defend its case. 

The market for RSV vaccine is estimated to reach $10 billion by 2030, according to analysts. Other contenders in this market are Sanofi and its partner AstraZeneca, that are working on a prophylactic monoclonal antibody for infants, and Bavarian Nordic, and Moderna that are currently in Phase 3 clinical trials for their vaccines. 

The race to make an RSV vaccine possible started several decades ago, in the late 1960s. Between 1966 and 1968, a promising clinical trial for an RSV vaccine had to be shut down after two young children that participated in the trial died and many more children ended up being hospitalized. 

It wasn’t until years later that scientists discovered that the virus that caused RSV shifted shapes, similar to SARS-CoV-2. Finally, in 2013, scientists from the National Institutes of Health (NIH) discovered a way to freeze the shape-shifting protein in one of its forms, thus making it possible to develop an antigen. 

Common during winter seasons, RSV garnered attention during the COVID-19 pandemic when it filled hospitals across the US with ailing children and older adults in 2021 and 2022. 

Image Credits: NIAID.

A dengue prevention worker sprays mosquito repellent in Bangkok, Thailand.

The number of dengue cases in the Americas has surpassed three million this year, as climate change makes people more vulnerable to the disease and the world more hospitable to the mosquitoes that carry it. 

Rising temperatures and shifting rainfall patterns are providing a boon to the Aedis aegypti mosquito, the main carrier of dengue. Warmer year-round temperatures are allowing the mosquitoes to thrive for longer periods of the year, and extending their mating season, allowing them to reproduce in greater numbers. 

Climate change is also extending the geographical range where the mosquito can survive, as warmer winters and milder autumns lead to fewer cold-weather deaths, meaning that more mosquitoes survive to adulthood.

“The mosquito in particular is a vector that has continually spread across the world,” Dr Raman Velayudhan, an expert at the WHO’s neglected tropical disease unit, told reporters on Wednesday. “It is a silent expansion … and right now a population of nearly 4 billion are at risk of this disease.”

The effects of global warming on the spread of Aedis mosquitoes are most visible in Brazil, which has already reported 2.4 million cases this year as mosquitoes invade its southern states, which are now hot enough to support them.

The incidence of dengue in Peru, Argentina and Bolivia has also risen sharply as a result of climate conditions. Peru has already recorded a caseload over four times higher than the average of the last five years – the country’s worst-ever outbreak of the disease. The outbreak in Argentina is also one of the largest in the country’s history. 

The World Health Organization (WHO) warned in July that the world is on track for over four million dengue cases in 2023, and that climate change is playing a significant role in its spread. The record for global dengue cases was set in 2019 when 5.3 million cases were reported. Global case numbers have risen eightfold since 2000, with 4.2 million reported in 2022.

Global dengue case numbers are vast underestimations, Velayudhan said, citing the 80% asymptomatic case rate and pandemic-disrupted reporting systems.

“We need to convey this message that dengue is a silent disease,” said Velayudhan. “We need to treat it as an endemic disease with epidemic potential.” 

Dengue can cause a range of symptoms, from mild fever to severe illness. There is no specific treatment for dengue, but early diagnosis and supportive care can help to reduce the risk of death. It is fatal in less than 1% of cases. 

A window into the future of dengue

mosquito
Aedes aegypti mosquito can spread Zika fever, dengue, and other diseases. Climate change is enabling their spread.

Computational epidemiologists at the University of Michigan have projected that Brazil’s epidemic potential for dengue could increase by 10-20% by 2040, as temperatures rise and rainy seasons get longer. This could lead to longer dengue seasons in Brazil, and could also be mirrored in other countries around the world.

The ongoing El Niño event, which is characterized by higher temperatures and extreme weather patterns, may provide a window into the future of dengue. Its effects on rainfall in the Americas and during monsoon season in Asia will likely play a large role in how close the world gets to the 5.3 million case record set in 2019.

In Bangladesh, monsoon rains have already led to a deadly dengue outbreak. Health experts in the country, including the Bangladesh Medical Association, have urged the government to declare a “public health emergency.” Some have compared the outbreak to the country’s 2019 dengue epidemic, which was so severe that many in Bangladesh refer to it as the “year of dengue.”

In July, meanwhile, changing climate patterns led the European Center for Disease Control to sound the alarm over the rising risk of mosquito-borne diseases across the continent, from which Europe has historically been protected.

“If this continues, we can expect to see more cases and possibly deaths from diseases such as dengue, chikungunya and West Nile fever,” Andrea Ammon, director of ECDC said at a press conference last month.

And the risks are not limited to dengue: Research shows the spread of over half of infectious diseases — including arboviruses like Zika, chikungunya and dengue — are aggravated by climate change.

Disease-carrying ticks, bacteria, algae and fungi and mosquitoes are all on the move. As the world warms, the diseases they carry will follow them as they expand their geographical reach to adapt to climate change.

Image Credits: Patrick de Noirmont/Sanofi Pasteur, Sanofi Pasteur/Flickr.

Bureau of Global Heath Security and Diplomacy
US Secretary of State Antony Blinken, Health Secretary Xavier Beccera, USAID head Samantha Power and new Bureau head John Nkengasong

The US has consolidated its efforts to address global health threats into a single structure, the Bureau of Global Heath Security and Diplomacy, which was launched on Monday.

Renowned Cameroonian health expert Dr John Nkengasong, appointed last year to lead the US President’s Emergency Plan for AIDS Relief (PEPFAR), leads the new structure and will report directly to US Secretary of State Antony Blinken. He also remains head of PEPFAR.

PEPFAR, the hugely successful HIV programme estimated to have saved 25 million lives over 20 years, will be incorporated into the new bureau alongside all other US efforts to address future pandemics and other health emergencies.

“We’re setting up a new bureau to focus fully on the need to drive both internal and international coordination and accelerate the State Department’s ongoing efforts to strengthen global health security so that the world can respond with immediacy and intention when the next health crisis emerges,” Blinken told the launch.

Blinked outlined three main functions for the Bureau, the first being to lead US diplomacy in  “strengthening the global health security architecture so that the world is better prepared to prevent, detect, control and respond to infectious diseases”. 

“That includes by working with partners to modernise existing organisations like the World Health Organization (WHO) so that they’re more fit for purpose and by shaping new structures like the Pandemic Fund,” said Blinken.

The second function is to “leverage US foreign assistance to strengthen public health systems, including laboratories and supply chains for vital medical counter-measures” to enable countries to be better prepared to address health threats.

The third is “to elevate health security as a core US foreign policy priority” through both international diplomatic engagement and health security policymaking across the US government.

Dr John Nkengasong leads the new structure.

Nkengasong said that some of the Bureau’s immediate priorities are to “strengthen the global health security architecture to ensure greater capacity, coordination and accountability”, including through the Pandemic Fund, amending the International Health Regulations and successfully negotiating a pandemic accord.

He also flagged the danger posed by antimicrobial resistance (AMR), which is projected to kill about 10 million people a year from 2050 if nothing is done to address it.

Describing PEPFAR as the US government’s most successful global health programme, Nkengasong said that the lessons learned from PEPFAR – particularly the importance of an “all of government response” – would be applied to the new Bureau. 

“We recognise that the frequency of the health threats has increased because of the greater connectivity, globalisation, climate change, population growth, food insecurity, and many others,” added Nkengasong, who headed the Africa Centre for Disease Control during the pandemic.

Samantha Power, Administrator of the US Agency for International Development, told the launch that the odds of living through another pandemic of similar severity as COVID-19 in our lifetimes was almost 40%.

“To give a sense of the need here, the WHO and the World Bank estimate that the annual funding gap in pandemic preparedness is $10 billion annually. This new bureau is going to play an absolutely vital role in coordinating with our partners to summon the global cooperation and the resource investments needed to keep us all safe,” said Power.

Rightwing threat to PEPFAR

Meanwhile, PEPFAR is facing a right-wing backlash based on misinformation, as reported recently by Health Policy Watch.

PEPFAR’s five-year budget is due for reauthorisation by the US Congress by 30 September, but there has been unprecedented right-wing mobilisation against it over the past few months by both US and African groups.

The US right-wing groups claimed in a recent letter sent to Senate and Congress leaders that PEPFAR grantees  “are using taxpayer funds to promote a radical sexual and reproductive health agenda”. Signatories include the Center for Family and Human Rights (C-FAM), Heritage Foundation and the Dr James Dobson Family Institute.

similar letter was sent on 6 June to the same US Senate and Congress leaders by some African politicians and religious leaders claiming that PEPFAR “is supporting so-called family planning and reproductive health principles and practices, including abortion, that violate our core beliefs concerning life, family, and religion”.

US Representative Chris Smith, who co-sponsored PEPFAR’s refinancing in 2018, has also joined its critics by recently claiming that the programme is being used to “promote abortion on demand”.

Illegal for PEPFAR to fund abortion

However, it is illegal for PEPFAR to fund or support abortion, and abortion is illegal in most of the  African countries where it operates.

“PEPFAR has never, will not ever, use that platform in supporting abortion,” said Nkengasong, as reported by Devex.

One of the PEPFAR grantees that have been singled out is DREAMS (Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe), which targets teenage girls in 16 African countries.

Girls and young women are up to five times more likely to contract HIV than boys and men their age, and DREAMS offered HIV prevention services to 2.9 million adolescent girls and young women in 2022.

“These people are all playing with fire, and they’re playing with people’s lives, and there can only be one reason: political motivation to kill PEPFAR,” Mark Dybul, former US global AIDS coordinator, told Devex.

Moderna
Moderna mRNA vaccine is found to be the safest for older adults. 

Older adults vaccinated with Moderna’s COVID-19 vaccine were 15% less likely to be infected with COVID-19 than those vaccinated with Pfizer-BioNTech’s, according to a peer-reviewed study, published in JAMA Network on Wednesday.

The study was based on observational data from 6.3 million adults, almost 60% women and 86.5% White, with an average age of 76 years old and were inoculated with either of the two mRNA vaccines against COVID-19. 

The results showed Moderna’s COVID-19 vaccine was also marginally safer with fewer post-vaccine adverse events like pulmonary embolism and thromboembolic events reported among the said group.

“The results of this study can help public health experts weigh which mRNA vaccine might be preferred for older adults and older subgroups, such as those with increased frailty,” Dr Daniel Harris, epidemiologist and the lead author of the study said. 

His team, at the Center for Gerontology and Healthcare Research at the Brown University School of Public Health, observed two groups of older adults, one with Pfizer-BioNTech’s mRNA vaccine and the other with Moderna’s mRNA vaccine for 28 days after receiving their first doses of the vaccines. 

Overall, only 1% of all the adults who participated in the study reported adverse events. Of these, those who received Moderna’s vaccine were associated with a 4% lower risk of pulmonary embolism (sudden blockage in blood vessels) and a 2% lower risk of thromboembolic events (several conditions related to blood clotting). 

Harris stressed that the risk of adverse events from contracting COVID-19 were substantially higher than the risk of adverse events from being vaccinated by either of the two mRNA vaccines.

“But in an ideal world where we can have a choice between which vaccine product is used, we wanted to see whether one vaccine was associated with better performance for older adults and those with increased frailty,” said Harris.

Long COVID clinical trials begin recruitment

Meanwhile, the US National Institute of Health (NIH), on Tuesday, launched the second phase of clinical trials to evaluate at least four potential treatments for long COVID. As part of the RECOVER Initiative, a range of  treatments will be evaluated through these trials including drugs, biologics, and medical devices.   

“The trials are designed to evaluate multiple treatments simultaneously to identify more swiftly those that are effective,” said the NIH in a press release

Created to study the long-term effects of long COVID, the RECOVER Initiative is currently conducting research on how COVID-19 affects the different tissues and organs in the human body, using data from over 24,000 participants, 60 million electronic health records, and over 40 pathobiological studies. 

The information gained from these studies has been used to design the second phase in which the safety and efficacy of long COVID treatments will be studied in groups of 300-400 people. 

“Hundreds of RECOVER investigators and research participants are working hard to uncover the biologic causes of long COVID. The condition affects nearly all body systems and presents with more than 200 symptoms,” Dr Walter J. Koroshetz, director of the NIH’s National Institute of Neurological Disorders and Stroke, and co-lead of the RECOVER Initiative, added. 

“Recognizing that more than one solution is likely needed, we’ve taken the lessons learned from RECOVER participants to design rigorous clinical trial platforms that will identify treatments for persons with different symptom clusters to improve their function and well-being.”

Image Credits: Gavi .