Charles Akim, a refugee from Sudan living in nothern Kenya, gets high blood pressure medication at Kenya’s Natukobenyo Health Center, as a result of a partnership between UNHCR, the Kenya government, Novo Nordisk Foundation, and others.

COPENHAGEN –  In Lebanon, international donors are supporting a network of public primary health care centers to test for diabetes and other noncommunicable diseases (NCDs), offering treatment equally to Lebanese nationals and Syrian refugees who are unlikely to return anytime soon to their war-torn homeland. 

In Kenya, a new national insurance law aims to make health insurance mandatory and accessible both to unemployed Kenyans as well as to the estimated 625,000 refugees that have been living in the country for 30 years or more. And a much-touted “Shirika” initiative aims to integrate refugee communities into the health workforce, as well as the broader economy. 

In both Moldova and Jordan, refugees fleeing war-torn Ukraine and Syria were immediately brought into the national health systems of their respective host countries at the height of the crisis.  That allowed international aid to be targeted to supporting refugee’s direct medical costs and even expanding national health system capacity, rather than building up a parallel system for the refugee communities.   

As humanitarian crises become more complex and more protracted, extending not years but decades, host governments, as well as United Nations aid agencies and major donor groups, are shifting tactics in an effort to extend to refugees a more holistic range of health services. The effort is particularly relevant when it comes to NCDs, which are often more expensive to diagnose and treat. And such services are not always widely available yet in many low- and middle-income countries that also host tens of millions of the world’s refugees. 

As such, policies and funding plans that simultaneously bolster NCD services for refugees as well as in national health services available to all citizens, may be particularly effective in closing multiple gaps simultaneously. 

The issue of integration was a key theme on the closing day of a three day meeting in Copenhagen on Noncommunicable diseases in Humanitarian Settings; Building Resilient Health Systems, co-organized by the World Health Organization (WHO) and UNHCR, the UN refugee agency.

‘Converging efforts’ is key, says WHO’s Santino Severoni (centre); on left Allen Maina (UNHCR) and on right, Waheed Arian, British radiologist and Afghan refugee.

“It’s paramount when you start a humanitarian response to look at the end system setting for the long term answers,” said WHO’s Director of Health and Migration, Dr. Santino Severoni, speaking Thursday in the closing hours of the event. 

“We see that all in those countries where there is a political commitment, where the political sensitivities about refugees have been diffused and the country is moving on with a rational approach, what is important is to provide support in order to converge efforts, expanding domestic capacity to finance access.  

“Every time we keep the situation in a protracted emergency. Every time we keep funding operations, not directly funding the country’s financial capacity, we are actually postponing the capacity of the country to be more effective.”

Extending Kenya’s social health insurance system to refugees means better NCD coverage

Elizabeth Onyango, Kenya Ministry of Health: Shirika means refugee inclusion, it is also a Swahili word that means coming together.

In Kenya, such an approach has led the government to extend the benefits of a new social health insurance fund intended to cover jobless Kenyan citizens to the country’s 625,000 refugees, who hail mainly from Somalia and Uganda, as well as South Sudan.

After overcoming several court challenges, this year’s plan rollout will extend coverage to tens of thousands of refugees living for decades in the Dadaab and Kakuma camps in the country’s remote northern and northwest regions. It also coincides with the government’s launch of the Shirika Plan, which calls for transitioning the sprawling camps into more open settlements.

“Shirika is an acronym which means social, economic hubs for integrated refugee inclusion,” said Elizabeth Onyango, who heads NCD Prevention and Control at the Kenyan Ministry of Health. “It also is a Swahili word that means coming together.

“So what does the government of Kenya envision? It envisions a situation where the refugee and host communities get together; they can work, play, and even love together. It is multi-agency and multi-sector” – including the health sector as part of the coordinating secretariat.

“For health, the Shirika plan wants to focus on enhancing access to comprehensive health services, including services for NCDs. Secondly, we also want to focus on building or improving the capacity or human resources to deliver the services, including the refugee and the host population, into the country’s social health insurance funding structure,” she said. “And lastly, we focus on preventing people from promoting health, preventing disease and disease surveillance in these regions.”

Integration of refugees will be enabled by the extension of the new Kenyan Social Health Insurance programme to all of the country’s residents.

The new initiative will ensure that primary health care is “free to anyone in Kenya, including refugees,” said Onyango. At secondary and tertiary levels, refugees will be able to obtain a social insurance card for a nominal payment on the same basis as Kenyan citizens, granting them free access to services.

In terms of health facility infrastructure in and around refugee communities, the emerging model is a hybrid with UNHCR, Kenyan county governments and NGOs working in partnership to ensure that health facilities in refugee communities can “provide a wide range of services from preventive promotive of primary health care all the way to tertiary and tertiary care,” Onyango said.

Refugees as part of the health workforce solution 

Charles, a Congolese refugee living in Nyankanda refugee camp in Burundi. He was diagnosed wih high blood pressure in 2017, and now works as a community health worker for the newly established NCD clinic.

Experts have applauded another critical element of the Kenyan plan: capacity-building in the refugee communities – to train a new generation of health workers.

This shifts refugees from being victims and recipients of aid from their host country to being an integral part of the solution. And it addresses the common problem of health worker migration from rural areas, where the most prominent camps are located, to the cities.

“We want to support [refugee] students with scholarships so they can get into medical training colleges,” said Onyango.

“Because one of the things we suffer is the retention of health worker staff; most staff are from other regions. Conversely, if more refugees from the far-flung camps are educated as health workers, she said it’s more likely they’d be willing to return to work in their home communities. She added that bolstering local capacity can help ensure that a full spectrum of NCD services are available in the communities.

“We want to ensure that we have the specialists who can go and mentor the healthcare workers, and at the same time, support groups established by people with lived experience, who can empower people to take charge of their health and ensure better management of their conditions,” she said.

Jordan – health enabling policies and programmes for everyone   

Dr Anas Almohtaseb director of the NCD Directorate in Jordan’s Ministry of Health (left) with Elizabeth Onyango, Kenyan Ministry of Health.

Jordan, host to one of the largest refugee populations in the world, is another country that has prioritised the integration of refugee health into the mainstream health services of the country.  

The country of 11 million people hosts nearly 760,000 refugees and asylum seekers registered with UNHCR. These are mostly Syrians who fled the country since the beginning of the civil war in 2011, but also Iraqi, Yemeni and Sudanese.  And that is not including some 2.3 million Palestinian refugees from the 1948 and 1967 Arab-Israeli wars, who hold Jordanian citizenship but are also registered with the UN refugee agency for Palestinians, UNRWA.  

While there are some health clinics run by UNHCR, UNRWA or affiliated charities, most are served in Jordan’s national system “available to all registered refugees from all nationalities at the non-insured Jordanian rate at public health centres and governmental hospitals”, according to UNHCR. 

“When the Syrian refugee crisis came, and they are our neighbors by the way, the services were provided free of charge for several years,” said Dr Anas Almohtaseb director of the NCD Directorate in Jordan’s Ministry of Health, speaking at the conference, which was co-sponsored by the Hasemite Kingdom, as well as Kenya and Denmark. 

Particularly in terms of NCD-related policies, many government initiatives “related to strengthening the healthcare system, will also strengthen the services provided for refugees,” Almohtaseb stressed, and vice versa. 

As an example, he cited tobacco cessation clinics – which are free and available to everyone, regardless of nationality.  Similarly, in terms of nutrition, Jordanian government plans to supplement basic goods like flour with critical vitamins would benefit the micronutrient status of everyone.   

Jordan also is in the process of updating its guidelines on cardiovascular disease prevention, diagnosis and care to align with the WHO HEARTS protocol, released in 2020. 

“Once we have these unified guidelines, this will help improve the services for every patient, whatever his nationality, said Almohtaseb. “And also we have the implementation of community engagement programmes, such as mental health care clinics, which will be inclusive for the whole population,” he said. 

Finally, digitisation of healthcare services, including better tracking of patients’ diagnoses and treatment, can help improve NCD coverage for refugees, who may be more mobile as they seek work and better living conditions, he pointed out. 

“Ultimately, the refugees affect the whole healthcare system. And for this reason, while NGOs are very important, we have to also be dependent on the public health system – that is crucial to the sustainability of the healthcare system in Jordan.”

New direction for the international health and development community 

Bent Lautrup-Nielsen, head of global advocacy for the World Diabetes Foundation (WDF).
Bent Lautrup-Nielsen, head of global advocacy for the World Diabetes Foundation (WDF).

Strategies that advance the integration of refugee health services with national health systems of host governments represent a “significant improvement” to the traditional approach to health emergencies, said Bent Lautrup-Nielsen, head of global advocacy for the World Diabetes Foundation (WDF).

“This is relatively new to the international health and development community,” Lautrup-Nielsen observed, noting that historically, institutional and funding drivers tended to foster more siloed approaches.

“For many years, the international system of humanitarian response has had its own mechanisms of funding – for example, through appeals by UNHCR, the Red Cross and many others,” and that led to focused emergency health efforts, more siloed approaches, he observes.

Over a decade ago, however, some organisations, including the World Diabetes Foundation, began to see that refugee health issues, with all of the urgency those often implied, could also be an essential entry point for boosting capacity for sorely needed NCD services in affected host countries.

“What we’re saying is that if you’ve got a refugee situation, then the donors should target the whole NCD population – not only refugees but also the host communities. If you start distinguishing between the refugee population and the local population, you risk creating uneven health access and inequities.”

In Lebanon – the refugee crisis led to new primary healthcare investments

Lautrup-Nielsen cites the Foundation’s experience supporting refugees in Lebanon, who fled to the country in the first phases of the Syrian civil war, as one example.

Public health clinics have traditionally played a relatively minor role in Lebanon’s largely privatised health services. However, these clinics became more critical due to the domestic economic crisis and the refugee inflow.

The new healthcare demands stimulated by the refugee crisis ultimately prompted a group of donor organisations, including WDF, the Danish Red Cross and Novo Nordisk Foundation, to support the expansion of NCD services in over 200 public primary health clinics nationwide, serving refugee and host populations. They are rolling out services for cardiovascular disease, diabetes and other conditions, including mental health.

“Building that as an integrated, basic package that wasn’t there before was a benefit to both Lebanese and refugees living in Lebanon,” Lautrup-Nielsen said.

But he notes that integration cannot be a one-size-fits-all approach. “Of course, there are acute emergencies at times that demand a dedicated humanitarian approach. We have a lot of that right now.

“But that cannot be separated from a long-term perspective,” he added. “And the COVID-19 pandemic crisis, which was considered a health emergency, showed that those who suffer the most are people living with NCDs.

“What came out of COVID was that realisation that you have to build resilient health systems that are meaningful in any context and serve everybody.”

Convergence instead of silos 

“Many [high-income] governments and private sector donors and foundations have willingly supported dedicated health services in response to humanitarian crises and emergencies – and for good reason. But this can also create imbalances or a lack of equity in a protracted situation.”

The inequities may also go both ways. In some low-income host countries, UNHCR-provided health services in refugee camps might even be regarded as “better” than what might be available in the local communities, Lautrup-Nielsen pointed out.

“But governments also wish to build equitable health systems, whether for refugees or local communities.

“Amongst the more than 150 countries represented at the conference, many are hosting refugees, and they are also appealing for a balanced international system, combining humanitarian response support in acute emergencies with protracted, long-term national health system strengthening.

“At the same time, most premature deaths from NCDs, before the age of 70, now occur in low- and middle-income countries of Asia, the Americas, the Middle East and Africa – and the disease burden is huge and growing fast.

“Five or ten years ago, this conference probably would not have been possible. But the thinking has matured a lot due to COVID and other things, not the least, because of the NCD agenda,” said Lautrup-Nielsen.

“To put things in a positive light, we are seeing a convergence within the health and development space and with other spaces like humanitarian response.”

Image Credits: UNHCR/Sala Lewis, UNHCR/Mia Bulow-Olsen , E. Fletcher/Health Policy Watch , E Fletcher/Health Policy Watch , UNHCR , Jesper Westley.

The sixth UN Environment Assembly was held in Nairobi

The sixth United Nations Environment Assembly (UNAE-6) ended last Friday in Nairobi, Kenya with the adoption of a Ministerial Declaration affirming member states’ commitment to slowing climate change, protecting biodiversity, and creating a pollution-free world.

The assembly, which attracted over 5,600 delegates from 190 countries, also adopted 15 resolutions covering a range of issues including chemicals, waste, metals and minerals and protecting the environment during and after conflicts.

“As governments, we need to push for more and reinvent partnerships with key stakeholders to implement these mandates. We need to continue to partner with civil society, continue to guide and empower our creative youth, and also with the private sector and philanthropies,” said Leila Benali, UNEA-6 President and the Minister of Energy Transition and Sustainable Development of Morocco. 

Benali noted that the resolutions called for enlightened leadership and urged scaling up means of implementation, enhancing national capacity to implement action plans and policies, and strengthening the science-policy interface.

Evidence of the extent of environmental degradation and its impact on individuals keeps rising. Along with updated estimates of air pollution-related deaths at 8.3 million annually, a host of recent studies have also linked excessive levels of air pollution with health issues ranging from increased neo-natal mortality to Alzheimer’s.  Most recently, one Nature study linked spikes in air pollution with increased risk of deaths by suicide. 

Leila Benali, UNEA-6 President and the Minister of Energy Transition and Sustainable Development of Morocco.

A slew of UN reports released during the assembly last week also presented a grim picture of the immediate future. Data from the 2024 Global Resource Outlook warned that without urgent action to reduce global consumption and production, extraction of natural resources could rise by 60 % from 2020 levels. This would worsen climate and pollution impacts, with consequently greater  risks to biodiversity and human health, the report said. 

It also blamed the high levels of material consumption in upper-middle and high-income countries for the problem. The report said that the rich countries use six times more resources and generate 10 times  climate impacts than low-income ones. 

The Global Waste Management Outlook 2024 showed that without a seismic shift away from ‘take-make-dispose’ societies towards circular economy and zero-waste approaches, the world’s waste pile could grow by two-thirds by 2050, and its cost to health, economies and the environment could double.  It reiterated that only a drastic reduction in waste generation will secure a liveable and affordable future, and ways to convert waste into a reusable resource would have to be employed.

Another UNEP report on Used Heavy Duty Vehicles and the Environment launched during a Climate and Clean Air Conference held ahead of UNEA, sounded the alarm on the rise of emissions from these heavy polluters, and their negative climate and health impacts.

Resolutions on improving response

The assembly also held its first Multilateral Environmental Agreements (MEA) Day that was dedicated to the international agreements addressing the most pressing environmental issues. UNEA-6 welcomed youth to host their own environmental summit, which called for greater inter-generational equity.

“The President has gavelled resolutions that address desertification, land restoration and more. We also have a ministerial declaration that affirms the international community’s strong intent to slow climate change, restore nature and land, and create a pollution-free world,” Inger Andersen, UN Evironmental Programme Executive Director, said.

“UNEP will now take forward the responsibilities you have entrusted to us in these new resolutions. In addition to keeping the environment under review. In addition to fulfilling our obligation to serve as an authoritative advocate for action across the triple planetary crisis,” Andersen added.

“In our quest to confront the monumental environmental challenges of our time—climate change, biodiversity loss, and pollution—there is but one path forward: teamwork. We share one Earth, bask under the same sun, and we must recognize that there is no backup plan. There’s no other planet waiting for us to escape to,” said Abdullah Bin Ali Amri, Oman’s chair of the Environment Authority and president-elect of the next UNEA, which will be held in December 2025 in Nairobi.

INB co-chair Precious Matsoso (right) injects some humour into proceedings after two long weeks of negotiations while co-chair Roland Driece looks on.

Text-based negotiations on a pandemic agreement will finally start at the next meeting of the intergovernmental negotiating body (INB) on 18 March, with the draft negotiating text due to be circulated to  World Health Organization (WHO) member states by this Friday, 8 March.

This follows an intense two weeks of the eighth round of INB negotiations, which ended on Friday (1 March) with member states expressing their confidence in the co-chairs and their deputies, who have been marshalling the informal talks so crucial to this process.

The INB has held 385 hours of formal meetings and over 80 hours of informal meetings over the past two years, and member states need to ensure this time was not wasted, co-chair Precious Matsoso told INB members at the close of the body’s eighth meeting last week.

South Africa’s Matsoso, injecting her characteristic good humour into the dry negotiations, closed the meeting with a quote from singer Sister Sledge, reminding member states that “we are family”.

However, like in most families, the INB has plenty of squabbles to iron out ahead of adopting any meaningful agreement.

Conditions for equity

Pakistan representing the Group for Equity at the pandemic agreement negotiations.

Pakistan, on behalf of the Group for Equity, delineated the most important areas for its largely developing country members at the closing session of INB8. These are also the issues over which there is no agreement.

Importantly, they want pathogen access and benefit sharing (PABS) system to “guarantee equitable benefit sharing on an equal footing, prohibiting anonymity to ensure transparency and accountability”.

PABS is one of the biggest sticking points in the negotiations, as previously reported by Health Policy Watch.

They want the agreement to contain “normative” technology transfer provisions in which countries have the right to “request and demand” tech transfer and licensing.

The group also wants country obligations, particularly related to surveillance and prevention, to be “proportionate to the respective capabilities and context”, build capacity in weaker countries and be in line with “the principle of common but differentiated responsibilities (CBDR)”. 

CBDR is commonly used in environmental law and means that countries’ obligations depend on their socio-economic status and historical contribution to environmental problems. 

The Group on Equity also wants “a predictable and sustainable financial mechanism” for pandemic prevention, preparedness and response that is part of the UN and “will ensure that resources are available in a timely and efficient manner, facilitating swift and effective responses to current and future health emergencies. 

Finally, the group wants governance over the agreement to be “designed to maximise participation and ensure accountability to the parties” and for a legally binding agreement that is “applicable and operable for all parties without any barriers”.

The Group for Equity comprises 29 countries representing an interesting alliance of largely African, Latin American and South and South East Asian countries, namely: Argentina, Bangladesh, Botswana, Brazil, China, Colombia, Dominican Republic, Egypt, El Salvador, Eswatini, Ethiopia, Fiji, Guatemala, India, Indonesia, Iran, Kenya, Malaysia, Mexico, Namibia, Pakistan, Palestine, Paraguay, Peru, Philippines,. South Africa, Tanzania, Thailand and Uruguay. 

Ethiopia representing the position of the Africa group during pandemic agreement negotiations.

Ethiopia, on behalf of the 47 African member states plus Egypt, wants a “multilateral pathogen access and benefit-sharing system with clear data governance and accountability for sharing pathogens” and a “dedicated financing mechanism with inclusive governance”.

Wishing for more progress

The European Union, on behalf of its 27 member states, urged negotiators to look at areas of agreement rather than divergence, which “are not insignificant” and provide “room there for a solid basis for continued good work that can get us to a successful outcome already by May”.

However, Germany “had somewhat wished to make more progress” during INB8  in “finding convergence”.  

“Time to come to convergence is extremely short. The text that will be presented next week is going to be crucial for all of us. It has to facilitate a meaningful outcome along the full PPR cycle,” said Germany.

“We also need to continue our discussions on an effective system for pathogen access and benefit sharing (PABS). PABS needs to be implementable. It must not hinder research and access and it needs to ensure reliable benefit-sharing with the necessary broad participation of the private sector.” 

The European Union at INB 8

Stakeholders: In or out?

A bone of contention during the negotiations is how little space civil society organisations (CSO), academics, the private sector and other stakeholders have had to express their views.

The Pandemic Action Network (PAN) organised two civil society sessions during the past INB meeting with the participation of around 100 organisations, many of which appealed for better access to the negotiations.

Last week, STOPAIDS, PAN and a number of other groups wrote a letter to the INB Bureau asking for the “official involvement of CSOs in all remaining negotiations in the INB process for a new pandemic agreement”.

“We demand the same rights accorded to civil society including as allowed during negotiations on (for example) the UNFCCC [UN Framework Convention on Climate Change], and the Convention on Biological Diversity,” they state.

“Not only will access for CSOs be crucial for reasons of transparency and legitimacy, but also because CSOs provide technical expertise and community testimony through briefings for negotiators during the official sessions. A broad range of member states has welcomed contributions from civil society during INB 8 but these have predominantly been made inside events in the margins of the negotiations. It is vital we form part of the process.”

The INB Bureau, in consultation with the WHO Secretariat, will propose a couple of options for the inclusion of stakeholders at the next meeting but Matsoso said that member states had agreed that stakeholders would not be in the room during negotiations. However, there could be regular reportbacks or a session where stakeholders briefed member states about the draft, she added.

Germany stressed that “strengthening our engagement with civil society, stakeholders and experts from all relevant areas is crucial. We look forward to their structured and meaningful inclusion during INB 9”.

A patient with age-related hearing loss (Presbycusis), receiving free treatment from the NGO, All Ears Cambodia.

Over 400 million people with hearing loss could benefit from hearing devices. However, less than 20% of those people actually get hearing aids. 

That’s one of the findings cited in new World Health Organisation guidelines on improving access to hearing care, published Friday, just ahead of World Hearing Day

“Unaddressed hearing loss is a global public health challenge and incurs an estimated cost of over US$ 1 trillion annually. Given the global shortage of ear and hearing care specialists, we have to rethink how we traditionally deliver services,” said Dr Bente Mikkelsen, director of the WHO’s Department for Noncommunicable Diseases.

By 2050, nearly 2.5 billion people are projected to experience a degree of hearing loss, as populations around the world age. More than 700 million will likely require hearing rehabilitation, estimates the WHO.

But nearly 80% of people with disabling hearing loss live in low-income countries – which historically have lacked capacity for providing assistive devices like hearing aids. 

Fighting misconceptions and lack of resources

But addressing hearing loss is not necessarily expensive. An investment of $1.4 per person annually would be sufficient to scale up ear and hearing care services worldwide, WHO said.

To overcome current limitations of capacity, the guidelines encourage more service delivery by non-specialists, based in primary health care settings. 

Debunking misconceptions and stigma around hearing loss is another key aim of the guidelines, created with the support of ATscale Global Partnership for Assistive Technology. 

“Common myths about hearing loss often prevent people from seeking the services they require, even where these services are available,” said Dr Shelly Chadha, technical lead for ear and hearing care at WHO. 

“Any effort to improve hearing care provision through health system strengthening must be accompanied by work to raise awareness within societies and address stigma related to ear and hearing care.”

Image Credits: WHO/Miguel Jeronimo.

WASHINGTON, DC – When US Senator Amy Klobuchar’s father, the late Jim Klobuchar, was diagnosed with Alzheimer’s disease, the noted Minnesota newspaper columnist gradually stopped recognizing her – although he retained “a kind of savoir faire” to the very end with words, jokes and storytelling based on the decades of “lines enmeshed in his memory,” she recalled.  

Senator Amy Klobuchar at an Alzheimer's disease event
Senator Amy Klobuchar (D-MN)

In the United States, one in every three seniors will be diagnosed with Alzheimer’s. The disease affects roughly 55 million people globally and is the seventh leading cause of death. 

“But it’s not just the numbers. It’s the fathers and mothers, it’s the brothers and sisters,” remarked Klobuchar, (D-MN), who recounted the story of her father’s illness at a high-level event here this week, organized by the Davos Alzheimer’s Collaborative (DAC) together with Scientific American. 

The meeting of the collaborative, a Swiss and US-based foundation launched at the World Economic Forum in 2021, brought together some 100 Alzheimer researchers and front-line clinicians as well as policymakers and industry and civil society advocates, to share progress on new innovations in diagnosing and treating the disease – as well as challenges faced in getting those same innovations into healthcare systems globally. 

But the event, co-hosted by Scientific American, also was marked by moments of personal reflections, both comic and tragic. Not only Klochubar, but other speakers in the room referred to their own experiences in dealing with family members with Alzheimer’s disease – what Senator Susan Collins (R-ME) termed “the defining disease” of her generation. 

Joining together across borders and cultures  

Older couple with Alzheimer's disease on a bench
Alzheimer’s is a growing issue worldwide as populations age

And while much of the attention around Alzheimer’s so far has been in the United States and other countries of the global north, the disease is a growing problem worldwide, as populations age and people live longer, but not always healthier lives. 

Researchers predict that lower and middle income countries will soon bear the brunt of Alzheimer’s disease – much as they already do with regards to other noncommunicable diseases. 

Worldwide projections of Alzheimer's prevalence
Alzheimer’s disease is projected to affect more than 100 million people globally 2050

And as in all disease research, a global approach can help identify new therapies more effectively and cost-efficiently.

“Rather than succumb to despair, what we’re doing is joining together across borders, cultures, and languages to chart a future for the world of prevention, effective treatment, and one day, a cure,” said Collins, who lost a brother to Alzheimer’s. Along with being vice-chair of the powerful Senate Appropriations Committee, Collins is also founder and co-chair of a Congressional Task Force on Alzheimer’s disease. 

George Vrandenburg davos alzheimer's collaborative
George Vradenburg, founding chairman of the Davos Alzheimer’s Collaborative

I want to speak on behalf of families…50 million families worldwide are struggling with this disease.” said DAC chairman George Vradenburg, who first launched the initiative in response to a challenge by WEF founder and executive director Klaus Schwab.  He said that DAC was committed to “including researchers, clinicians and families in this fight globally, ensuring that no corner of the world is left untouched by our efforts.” 

Added Collins, “We need a global approach modeled on what we’ve done with AIDS, tuberculosis, and malaria. And we know that that kind of global collaborative approach to bring the research directly to a broader spectrum of countries and communities will remove long standing barriers to care and help us eliminate disparities.” 

“A transformative moment”: Novel diagnostic tests, gene sequencing, and precision medicine

Panelists discuss Alzheimer's disease research
Moderator Jeremy Abbate, VP and publisher of Scientific American with former NIH Director Dr. Elias Zerhouni, University of Washington’s Dr. Suzanne Schindler and Dr. Jeffrey Burns, University of Kansas Medical Center

Early Alzheimer’s disease research was rather akin to “staring up a cliff,” said former US National Institutes of Health (NIH) director Elias Zerhouni, one of the other speakers at the event. Now, however, the world has reached a turning point where, “we can truly have a global approach.”  

Improved genetic sequencing, the advent of digital and biological markers, novel drugs, and a more open mindset to alternative hypotheses have seen Alzheimer’s disease research leap into a new era. 

“We have an explosion of ways to test for Alzheimer’s disease,” remarked Suzanne Schindler, Associate Professor of Neurology at Washington University School of Medicine. Among them are blood tests that can measure up to 5,000 various proteins- a method faster and less invasive than dreaded spinal taps. 

Other panelists shared this optimism, citing the use of amyloid pet-scans and other diagnostics to more accurately assess Alzheimer’s progression in patients.  Genetic sequencing too is cheaper, a marked change since the early days when researchers remained in the dark about the potential genetic drivers of the disease.  

‘More than buildup of amyloid plaques’ 

Alzheimer's disease and tau proteins
One of the causes of Alzheimer’s appears to be the abnormal accumulation of tau proteins in the brain, eventually forming tangles inside neurons, seen here

With these tools comes an understanding that “the disease is more than just about build up [of amyloid plaques],” commented Jeffrey Burns, Professor of Neurology at University of Kansas Medical Center. 

New research into disease risk factors is moving beyond conventional descriptions of amyloid plaques and tau protein pathways to include research into inflammation and lifestyle factors. 

The future of prevention, he speculated, will increasingly lie in more holistic lifestyle approaches undertaken in tandem with medications. “We don’t just give patients with heart disease medication, we tell them to modify their diet, their lifestyle.

“I believe we will prevent the disease,” Burns added. 

Early Alzheimer’s detection remains a missing link

Panelists discuss aging and Alzheimer's disease at an event in DC
Phyllis Ferrell (center left,) Arindam Nandi, and Terry Fulmer discuss the implications of an aging society with Jeremy Abbate.

One major challenge is the need to move new knowledge into hospitals and health clinics; currently it can take as long 17-20 years for innovations to get into clinical practice due to outdated models of care. 

“We are building bullet trains, but running them on the same wooden tracks,” said Dr Phyllis Ferrell, DAC advisor on healthcare systems preparedness. 

Too often, practitioners still take a “wait and see” approach, while symptoms of cognitive impairment go unrecognized or undiagnosed until much later in the disease course. She urged a shift to a more preventative approach with screenings and help manage cognitive symptoms early.

“Why did it take four separate visits to get my dad an inconclusive diagnosis?” Ferrell asked.

“Early detection gives people the time to focus on what matters most to them,” she added. “It provides an opportunity to implement positive lifestyle changes and address risk factors, pursue treatment options and/or enroll in a clinical trial.”

Getting new innovations into practice 

Ferrell also bemoaned the frustration families feel over the lack of access to new diagnostics and therapeutics – in the wake of progress made in research. 

In 2010 the NIH funded Alzheimer’s disease research to the tune of $400 million annually. Fourteen years later, the annual investment is now close to $4 billion, she noted. 

Yet, despite this influx of funding for research, there’s a huge gap emerging in affordable and available drugs. 

“We have innovations that are ready, but are not being used,” she said, adding “Yes, to research, but we need to do things today. Let’s go after clinically ready innovations.”

Staying the course on research 

Senator Susan Collins (R-ME)- a leading champion in Congress for Alzheimer’s disease research.

At the same time, more research into the disease remains critical to find even more effective preventive strategies as well as possible cures.  This means building specimen repositories across the country, performing skin tests for early detection of Alzheimer-related protein abnormalities traditionally only detectable from brain biopsies, and other research. 

Zerhouni called it breaking the “taboo of the brain” – an area of human physiology where research was historically inadequate. “This is a frontier that has to be broken.”

For many years, such research was impeded by social taboos around Alzheimer’s disease. “People used to just call it senility,” said Collins, who has been the leading champion of Alzheimer’s research and action on Capitol Hill for over a decade. 

Collins last year initiated bipartisan legislation in the US Congress to help maintain the funding for Alzheimer’s research, as well as supporting initiatives to bring down the cost of new drugs in the US for Alzheimer patients. At $345 million billion a year, the disease is currently the most costly disease in the nation to treat, she says. 

A global economic burden 

Globally, Alzheimer’s disease also presents an enormous economic burden – costing the world’s economies some $1.3 trillion, in terms of medications as well as care – much of it unpaid, noted Population Council economist Arindam Nandi.  

In the past, economic data came mostly from high income countries, Now, data is available from lower and middle-income countries like India and China. 

“These data depict a worrying trend; the percentage of unpaid care is higher in these countries, meaning that caregivers are not able to get other jobs, decreasing economic output,’ he said. 

 

Nandi also mentioned that predictive models forecast the shifting burden of disease from high income countries to middle and low income countries. “We don’t know how these populations will fare.” Investments in these countries are needed to strengthen their overall public health measures. 

Meanwhile, the US and high income countries can learn from the experiences of low and middle income countries, which often are first to devise lower-costs methods for detecting and treating diseases.

DAC, for instance, funded an Early Detection Flagship program involving six countries, including the US, Scotland, Jamaica, Japan, Mexico and Brazil. They participated in a pilot designed to increase access to early detection and diagnosis of the disease through the use of innovative new screening tools. 

“One of the things I loved [about the Early Detection program]  was watching the US and high resource countries learn from LMICs,” Ferrell observed. “As the founder of the Brain and Mind Institute of Aga Khan University once said, ‘when it comes to Alzheimer’s disease we are all developing nations.’ “

Image Credits: Getty Images, Pixelmestudio/DAC, National Institutes on Aging , UCLA , S. Samantaroy/HPW.

Member states have been slow to implement WHO policies to address obesity, including taxes on sugary drinks and restrictions on marketing junk food to kids

The private sector “must be held accountable for the health impacts of their products”, warned the head of the World Health Organization (WHO) amid news that obesity has quadrupled in children and more than doubled in adults since 1990.

Dr Tedros Adhanom Ghebreyesus was speaking ahead of the release of a huge global obesity study involving over 220 million people from more than 190 countries published in The Lancet on Friday. 

“Getting back on track to meet the global targets for curbing obesity will take the work of governments and communities, supported by evidence-based policies from WHO and national public health agencies,” added Tedros.

Countries with highest obesity rates 2022

Tonga, American Samoa and Nauru have the world’s highest obesity rates, affecting some 60% of their adult populations. 

“The largest increases are in some countries in the Pacific, the Caribbean, the Middle East and North Africa, and some of the newly high income countries like Chile,” said senior author Professor Majid Ezzati, of Imperial College in London, at a media briefing on Thursday.

The US is the only high-income country that features in the ten worst affected countries – with the 10th highest obesity rate in men. Some 43.8% of US women and 41.6% of men were living with obesity in 2022.

Meanwhile, obesity is slowing in a handful of west European countries – notably Spain and France. However, countries with the lowest obesity rates are generally low-income countries with high rates of under-nutrition, with a few exceptions such as Japan and Viet Nam.

Countries with lowest obesity rates 2022

Huge rise in child obesity

In 1990, around 31 million children (2,1% of boys and 1.7% of girls) were obese. But 32 years later, there had been a fourfold increase in both boys (to 9,3%) and girls (6.9%) affecting almost 160 million children.

“It is very concerning that the epidemic of obesity that was evident amongst adults in much of the world in 1990 is now mirrored in school-aged children and adolescents,” said Ezzati.

Professor Majid Ezzati, of Imperial College in London

While boys are more likely to be obese than girls globally, this trend is reversed in adulthood with many more women than men living with obesity. 

But men seem to be catching up. Obesity in men has nearly tripled over the past 32 years, while it has doubled in women. 

“Different forms of malnutrition still coexist in many countries,” said Dr Francesco Branca, WHO Director of Nutrition and Food Safety and one of the co-authors of the study. 

“The child who was undernourished in the first years of life can later become overweight or obese as an adolescent or an adult. Undernutrition and obesity are two faces of the same problem, which is the lack of access to healthy diets.”

Greater risk of NCDs

Undernourished people are more susceptible to infectious diseases, while obesity can lead to Type 2 diabetes, heart disease, certain cancers and affect bone health and reproduction, added Branca, who was also addressing the briefing.

“The increase in the double burden of malnutrition is a result of a transition in food system and lifestyle that has not been governed by public health policies,” he added.

However, despite WHO guidelines on what countries can do to address the massive rise in consumption of energy-dense ultra-processed food, adoption by member states has been slow.

At the World Health Assembly in 2022, member states adopted the WHO Acceleration plan to stop obesity. Core interventions include promoting breastfeeding,  regulating marketing of ultra-processed food and drinks to kids, taxation and warning labels on foods high in fats, salt and sugar.

Dr Francesco Branca, WHO Director of Nutrition and Food Safety

“The reason why the epidemic has progressed so quickly is because the policy action has not been incisive enough,” said Branca, adding that countries had focused on behaviour change rather than “structural elements, which is the policies around food environment”. 

However, he added that more countries were taxing sugary drinks, although “not many countries have done it for sufficiently long time and in ways that are demonstrated to be most effective”. 

“Very few countries put a restriction on marketing food to children. We know that some South American countries are taking that action much more effectively, and we look forward seeing the impact of those policies,[as well as] having warning signs on the processed food which would really discourage people from f buying products which are high in salt, sugar and fat”.

If these policies were implemented, this would likely lead to food and beverage companies reformulating their products to reduce harmful ingredients, he added.

Role of new weight-loss pills?

Branca said that the WHO was currently looking at the efficacy of the new drugs called glucagon-like peptide 1 (GLP-1) agonists – such as Wegovy, Ozempic – which have been approved as weight-loss medication in some countries.

“The solution is still is a transformation of the food system and in the environment such obesity can be prevented,” Branca stressed.

However, the GLP-1 drugs could provide a tool to help those that already live with obesity, as long as they were integrated into a primary healthcare package to manage obesity that included guidance on exercise and diet.

The new study was conducted by the NCD Risk Factor Collaboration (NCD-RisC), in collaboration with the World Health Organization (WHO), and involved over 1,500 researchers. They based their analysis on body mass index (BMI). Adults with BMI 30kg/m2 and over were classified as obese and underweight if their BMI was below 18.5kg/m2. For children, BMI was adjusted according to age. .

Image Credits: World Obesity Federation.

Covid-19 pandemic
Thousands of small white flags representing Americans who have died from COVID-19, outside the DC Armory in Washington DC.

The overall benefits of COVID-19 vaccines far outweigh potential risks, according to a recent study of 99 million vaccinated people – despite a number of misleading and sensational reports about the study. 

The study, published in the journal Vaccine in mid-February, aimed to get more precise estimates of the risk of adverse events following vaccination.

Researchers used data collected from over 99 million vaccinated individuals, who took a total of 183 million Pfizer doses, 36 million Moderna doses and 23 million AstraZeneca doses. 

The study specifically noted a slightly elevated risk of myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the lining around the heart) following Pfizer and Moderna mRNA vaccines, and Guillain-Barré syndrome and cerebral venous sinus thrombosis (blood clot in the brain) after taking the AstraZeneca shot. 

“The risk of side effects like myocarditis from the vaccine is extremely low; the risk of developing it from COVID can be many times higher. The study is just reinforcing what we already learnt from previous studies,” stressed Professor Nadav Davidovitch, an epidemiologist, public health physician and head of Ben-Gurion University of the Negev’s School of Public Health. 

Rare adverse events

“Anytime a medicine or a vaccine is approved and introduced into wider use, rare adverse events are found in the population that would be impossible to find in clinical trials,” Prof Katrine Wallace, an epidemiologist at the School of Public Health at the University of Illinois at Chicago, told  Health Policy Watch.

COVID-19 vaccines were globally introduced in 2020, just a year after the virus emerged. The swift rollout prompted intense monitoring, surpassing most other vaccines or drugs. 

“The study methodology examined the observed versus expected ratios: observed post-vaccination rates from a pre-specified list of adverse events to the expected rates, or the historical, background rate of the same events calculated from the same populations during 2015-2019, before the vaccines were available,” Wallace explained in a recent op-ed on MedPage Today

This observational study looked at 13 adverse events of particular interest across neurological, haematological and cardiac outcomes and found four statistically relevant ones. 

Guillain-Barré syndrome occurred after the first dose of AstraZeneca’s viral vector vaccine. The observed to expected (OE) ratio was 2.49.

Cerebral venous sinus thrombosis, also known as TTS blood clots, happened after the first AstraZeneca dose, with an OE ratio of 3.23.

Acute disseminated encephalomyelitis occurred after the first dose of Moderna’s mRNA vaccine (OE 3.78). However, this wasn’t found in a more thorough follow-up study by the same group.

Myocarditis and pericarditis happened after Pfizer and Moderna’s mRNA vaccines, as well as AstraZeneca’s viral vector vaccine. (OE of slightly over 1.5).

The data was taken from 10 sites across eight countries and processed by researchers from the Global Vaccine Data Network, and the US Centers for Disease Control and Prevention (CDC) funded the study. 

Wallace told Health Policy Watch that myocarditis and pericarditis were more common in young males aged 15 to 24 after the second vaccine dose. However, any myocarditis or pericarditis that did happen was typically mild and resolved independently without requiring extensive treatment like that needed for COVID-induced cases, she added.

One-in-a-million

Cerebral venous sinus thrombosis was linked to the viral vector vaccines AstraZeneca in this study and Johnson & Johnson in various other studies. Wallace noted that in the United States, approximately six cases were attributed to the J&J vaccine early on. When these cases, mainly affecting older women, were identified, the vaccine was deprioritized, indicating the effectiveness of the monitoring system.

“Many people who don’t understand vaccine safety surveillance think this information was hidden or the trials were not long enough,” Wallace said. “If something is one-in-a-million, you would need a million people in a clinical trial to find one case. We only find rare events after rollout.”

There is no vaccine or medical treatment with no risk, explained both Wallace and Davidovitch.

“The bottom line is that no medication or vaccine is 100% effective or 100% safe,” Wallace said. “Everything has risks and benefits. However, any risks from medications and vaccines must be balanced against the dangers of the disease you are trying to prevent.”

She added that “COVID-19 has killed over a million people in the US and has led to permanent disability in many others. The vaccines are very safe overall, and the benefit of the vaccine still definitely outweighs the risks.”

Booster Vaccines for Seniors

On Wednesday, the CDC recommended that adults over 65 receive an updated COVID-19 vaccine shot after previously recommending boosters for people who are immunocompromised. 

The CDC statement highlighted that individuals aged 65 and older are particularly affected by COVID-19. It reported that over half of the COVID-19 hospitalizations from October 2023 to December 2023 involved people in this age bracket.

The CDC “recommendation allows older adults to receive an additional dose of this season’s COVID-19 vaccine to provide added protection,” said CDC Director Mandy Cohen. “Most COVID-19 deaths and hospitalizations last year were among people 65 years and older. An additional vaccine dose can provide added protection that may have decreased over time for those at highest risk.”

“We are now dealing with the JN.1 COVID strain, which is very infectious,” Davidovitch said. “We still need to be cautious.”

Image Credits: Ron Cogswell.

Ghana’s parliament passes a draconian anti-LGBTIQ Bill.

Ghana’s Parliament unanimously passed one of the world’s most draconian anti-LGBTIQ Bills on Wednesday, including a mandatory three-year prison sentence for a person who simply “identifies” as lesbian, gay, bisexual, transgender, intersex or queer.

Anyone funding an LGBTIQ organisation also faces five years in prison, while LGBTIQ “advocacy” involving children will result in a 10-year prison sentence – a clause that is so wide it could be applied to sex education in schools.

Any media that reports or broadcasts anything related to LGBTQ+ people or activities also face fines and possible prison sentences.

People who allow same-sex “activity” on properties they “own, occupy or manage”  face six years in prison.

Ghana’s Human Sexual Rights and Family Values Act also prohibits LGBTIQ+ groups, criminalises anyone advocating for these groups and obliges citizens to report “perceived homosexuals or homosexual activity” to the police or community leaders. It also outlaws sex toys

In many ways a copycat of Uganda’s Anti-Homosexuality Act, the MPs behind laws in both countries have been fêted at meetings organised by US far-right Christians, particularly Family Watch International (FWI).

Mostly recently, the MPs met at a meeting in Entebbe in last April at the African Inter-Parliamentary Conference on Family Values and Sovereignty, where they discussed laws to “protect family values”.

Ghana’s Bill, which was championed by MP Sam George as a Private Member’s Bill, will become law only once it has been signed by Ghanaian President Nana Akufo-Addo.

Earlier in the week, a group of Ghanaian lawyers known as the “Big 18” and Human Rights Coalition wrote to the president urging him not to sign the Bill into law as it “violates key fundamental human rights provisions in Ghana’s 1992 Constitution” by infringing on “rights to dignity, freedom of speech, freedom of association, participation in processions, academic freedom, equality, and non-discrimination”.

“Rights are the pillars upon which democracy rests to prevent the tyranny of the majority,” they added.

Noting that Ghana is a secular democratic country, they state that any attempt to criminalise what some regard as a sin through the instrumentality of the state violates the long-standing principle of separation between church and state.

Meanwhile, UNAIDS executive director Winnie Byanyima warned that if the Bill becomes a law “it will exacerbate fear and hatred, could incite violence against fellow Ghanaian citizens, and will negatively impact on free speech, freedom of movement and freedom of association”.

Byanyima added that it “will obstruct access to life-saving services, undercut social protection, and jeopardize Ghana’s development success.Evidence shows that punitive laws like this Bill are a barrier to ending AIDS, and ultimately undermine everyone’s health.”

MPs claim that they introduced the Bill after an LGBTQ office was opened in Accra in January 2021, and have dared developed nations to impose sanctions. 

After Uganda passed its Anti-Homosexuality Act last year, the World Bank suspended new loans and the US halted some HIV-related aid to the government.

This boy  gets vaccinated against measles during a WHO vaccination drive.

Outbreaks of measles have affected parts of the United States, coinciding with the lowest child immunisation rates the country has seen in 10 years, according to a report from the Centers for Disease Control and Prevention (CDC).

By 22 February, 35 measles cases had been reported by 15 states, namely Arizona, California, Florida, Georgia, Indiana, Louisiana, Maryland, Minnesota, Missouri, New Jersey, New York City, Ohio, Pennsylvania, Virginia, and Washington, according to the CDC.

However, unlike other parts of the world where measles is rife because immunisation programmes have been disrupted by conflict or weak health systems, the drop in child immunisation in the US is parent-driven. 

In 2023, the highest number of parents filed for their children to be exempted from school vaccination requirements. Immunisation with the measles, mumps, and rubella vaccine (MMR) dropped in 29 states in 2023, while exemptions increased in 40 states and DC, with 10 states reporting an exemption from at least one vaccine for more than 5% of kindergartners, according to the CDC.

The CDC reported that its childhood immunisation rate for all three required childhood vaccines – MMR, polio and diphtheria, tetanus, and acellular pertussis vaccine (DTaP) – is 93%, whereas the threshold for herd immunity is generally regarded as 95%. 

“National MMR coverage among kindergarten students remained below the Healthy People 2030 target of 95% for the third consecutive year,” according to the CDC. Idaho reported the lowest rate (81.3%) and Mississippi, the highest (98%).

“National MMR coverage of 93.1% during the 2022–23 school year translates to approximately 250,000 kindergartners who are at risk for measles infection.”

Most contagious disease

Measles is one of the world’s most contagious diseases, spread by droplets from infected people coughing or sneezing.

“The virus remains active and contagious in the air or on infected surfaces for up to two hours. For this reason, it is very infectious, and one person infected by measles can infect nine out of 10 of their unvaccinated close contacts,” according to the World Health Organization (WHO).

Most deaths from measles are from complications related to the disease, including encephalitis, severe diarrhoea and pneumonia.

It also has a long incubation period, which is why there has been controversy over Florida’s Surgeon General Dr Joseph Ladapo’s decision to allow the parents of unvaccinated children to ignore the CDC’s advice that they should quarantine for 21 days.

Europe has also seen an increase in cases: “Last year, more than 58 000 people in 41 of the 53 member states in the region – straddling Europe and central Asia – were infected with measles, resulting in thousands of hospitalisations and 10 measles-related deaths,” according to WHO Europe.

“The high proportion (nearly half) of cases among children below five years of age reflects, once again, the enormous impact of the COVID-19 pandemic on health systems, including routine immunisation services. This has resulted in a significant accumulation of susceptible children who have missed their routine vaccinations against measles and other vaccine-preventable diseases.”

“Vaccination is the only way to protect children from this potentially dangerous disease. Urgent vaccination efforts are needed to halt transmission and prevent further spread,” explained Dr Hans Henri P.Kluge, WHO Regional Director for Europe.

Image Credits: WHO.

Several hundred representatives of WHO member states, UN agencies and civil society meet in Copenhagen on the intersection of humanitarian crises and non-communicable diseases

COPENHAGEN –  While conflict and natural disasters are usually played out in the media against dramatic scenes of mass casualty response and rescue teams, there’s an iceberg of chronic health conditions that can be even more life threatening and these need far greater attention in emergency response. 

That is the theme of a global high level meeting here this week – which aims to raise the profile of non-communicable diseases (NCDs) in humanitarian settings.

The health officials from most of WHO’s 194 member states, as well as UN non-governmental organizations and relief agencies, convenes as the world faces more humanitarian crises as a result of conflict, climate change and natural disasters, than almost anytime in the last half century. 

The past 10 years has seen a three-fold increase in displaced people – some 117 million people in total as compared to about 40 million only ten years ago, said Sajjad Malik, of the UN High Commission on Refugees (UNHCR) which co-organized the meeting along with WHO. 

More emergencies and displaced people than ever before

In 2023, WHO responded to 63 health emergencies worldwide, up from an average of 40 a year a decade earlier. This includes both acute as well as protracted crises in settings ranging from the massive earthquake that hit Türkiye and Syria in early 2023, to grinding wars in Ukraine, Sudan, and most recently, Gaza.  

At the same time, some 70% of premature deaths [before age 70] are attributable to chronic diseases including diabetes, cardiovascular and lung diseases and cancer, and most of these deaths occur in low- and middle-income countries. 

 “We are facing a tsunami of NCDs,”  declared Dr Faras Hawari, Minister of Health of Jordan, which is co-hosting the meeting together with Denmark. 

People living with NCDs are among the first victims of all disasters

WHO Health Emergencies Executive Director Mike Ryan (left); Dr Bente Mikkelsen, WHO Director of NCDs (seated).

“We are living in a perma-crisis of emergencies and tensions. They also blur  the artificial distinctions that we tend to make between communicable diseases and non communicable disease, between one country and another,” said WHO’s European Regional Director, Hans Kluge, also speaking Tuesday. 

What few may realize, however, is that people living with NCDs are typically “among the first victims of all disasters,” Kluge added later at a press briefing. “They are at increased risk during emergencies. For example, the incidence of stroke and heart attack are up to three times the normal levels.” 

Traditionally, health sector response to humanitarian emergencies was designed to deliver  “surgical teams and mass casualty management, epidemic prevention, response and immunization campaigns,” remarked WHO’s Executive Director of Health Emergencies, Mike Ryan.

“But what we don’t see is the iceberg of mortality that occurs because people lose access to those long term services that keep people alive and well,” Ryan said. 

Recalling scenes from the early days of Russia’s invasion of Ukraine, Kluge described meeting with “elderly women with heart problems, diabetes, typically which can be managed. But all of a sudden these management conditions become life threatening.”

Calls for Gaza cease/fire continued UNRWA funding 

Dr Feras Hawari, Jordan’s Minister of Health.

The conference takes place as conflicts in Sudan, Gaza and elsewhere continue to create acute disruptions to health services and systems, upon which chronic care, as well as acute disease and injury management, depend. 

“There are about 13,000 cancer patients in Gaza and only about 2000 have been able to get therapy or treatment.  At this point it’s very complex, and difficult to manage these patients,” said Hanan Balkhi, director of WHO’s Eastern Mediterranean region, which covers an arc of  North African and Middle Eastern countries from Libya to Afghanistan, including Israeli-occupied Palestinian territories. 

“We continue to witness in real time one of the most devastating humanitarian crises of the century,” said Hawari, of the Gaza crisis. 

He and Ryan repeated previous calls for an urgent ceasefire, as well as for continued funding for the UN Refugee Works Agency (UNRWA), which they described as a critical backbone of Gaza’s health system.  

“We need to support an immediate end of this bloodshed and allow the entry of humanitarian and medical teams,” Hawari said of the Gaza situation.  

Al-Aqsa Hospital in central Gaza in January.

“Over half of all public health care in Gaza is delivered directly by UNRWA,” asserted Ryan. “Over 1.3 primary health consultations have been delivered by UNRWA since October 7. And they are intimately involved in the delivery of non-communicable disease care, all across Gaza and beyond.”  

UNRWA has faced a crisis of confidence amongst key donors in the wake of Israeli allegations that some employees joined the Hamas forces that led the 7 October invasion of some two dozen Israeli civilian communities, killing over 1200 people. Days afterward, Israel invaded the tiny enclave in a bitter war with Hamas that has now led to the deaths of nearly 30,000 Palestinians. 

Ryan added: “Since the beginning of the conflict and October 7th, and despite the horror of what has befallen the Israeli people in the barbaric attacks on civilians, the reality is that the catastrophe that has unfolded in Gaza must stop,” he concluded, to a round of applause. 

Eastern Mediterranean region is hotbed of crises 

Hanan Balkhy, Director of WHO’s Eastern Mediterranean Region (left) and Jérome Salomon, WHO Assistant Director General NCDs.

“The conflict in Gaza stands as one of the most challenging crises in modern history,” added Balkhy, who took up her post as EMRO regional director a few weeks ago.   

“The conflict has depleted an already under resourced health systems. Thousands were killed or injured and over 1.6 million displaced, including 350,000 people living with chronic conditions.”

But Gaza is not alone. Throughout the eastern Mediterranean region, conflict-related crises abound, and so do NCDs.

“The Eastern Mediterranean region is home to 745 million people. Of those, 140 million require humanitarian assistance. That is almost one in every five people. The region is the source of 58% of the world’s refugees, and 33.7 million people have been forcibly displaced among its 22 countries and territories – 13 are directly or indirectly affected by conflict; nine are classified by the World Bank as fragile state state situations,” Balkhy said.  

“Regionally, two-thirds of annual deaths are attributable to NCDs. The likelihood of premature deaths due to NCDs range from 17.8% in non-fragile or complex affected settings to 25% in fragile and conflict-affected contexts.  Cases of heart attack or stroke, asthma might double or even triple in frequency immediately after a disaster.

Identifying technical bottlenecks to ensure access is important, but only one dimension of a multi-pronged challenge. For instance, the region’s political and economic fragility makes it much more difficult to develop and maintain a robust health workforce, she observed, saying: “Health worker retention is extremely complex. It’s like a sieve with big holes.”

Sudan – from reform to collapse

Dispersion of Sudanese refugees around Africa

“Before the war, Sudan was undergoing robust health system reform,” Balkhy added, citing the other great regional hotspot. “However, after 10 months of conflict, the health system is reaching collapse. Over 7 million people remain displaced, while  1.7 million people are seeking refuge in neighboring countries. 

“The conflict has led to over 13,000 deaths and 26,000 injuries. Around 9,000 haemodialysis patients including 240 children, face severe risks due to service disruptions and 4,500 kidney transplant patients require uninterrupted treatment.  Since April 15 WHO has verified 60 attacks on health care leading to 34 deaths and 38 injuries among the health workforce. 

“Attacks on health care include attacks on health facilities, transport personnel, patients, supplies, and warehouses. Refugees and migrants face barriers to accessing health care especially for the management of NCDs during protracted crises.”

 NCD kits and local solutions  

Display of NCD Kits at along with a listing of essential medicines and equipment that they contain.

Despite growing awareness of the need for addressing NCDs in the health emergencies context, ”there remains a considerable journey head to fully integrate NCDs into the [WHO] Health Emergency and Response agenda,” Balkhy said.  

One successful approach has involved the development of NCD kits containing a pre-packaged set of basic healthcare supplies for treating diabetes, cardiovascular issues and strokes. So far these have been distributed in humanitarian settings in 28 countries around the world, Ryan noted. 

But standardized solutions also fall short, stressed Kluge, “We need local solutions for local challenges. In Ukraine, we started dispensers for medicines where health facilities were destroyed. In Turkiye, it was mobile health teams. 

“Each context is unique,” added Ryan. “If you go to a village in the Ukraine, it will be a very different age and disease profile than a refugee camp in Uganda.”

Additionally,  finding  “sustainable resources” to add NCD solutions to packages of humanitarian health care remains the other big  challenge, particularly in light of the burgeoning number of such crises.  While some donor countries, such as Denmark,  continue to make very significant contributions to crisis response, available funds falls far short of the swelling needs, Ryan said. 

Health worker retention and attack  

A severely injured patient is evacuated from Gaza’s Nasser Hospital – healthworkers continue to perform at risk to their lives.

And kits of equipment and medicine are not enough on their own, Ryan stressed, 

Taking diabetes as one example, Ryan explained that preserving the cold chain so as to get  insulin to a crisis zone is only the first step in a much more complex process.  

“It’s not just the insulin,” he said. “It’s the care package that goes around the insulin. It’s the knowledge of the health worker for dosing, it’s the self-testing of the sugar levels. 

“We are doing that right now in Gaza, the advantage that we have despite the huge degradation of the system, we still have health workers who go to work every day. 

However, health workers in some parts of the world, including Gaza, Ukraine and Sudan also face daily threats, just as a result of showing up to work.    

“We don’t have the protection for the health workforce in the field,” said Ryan. “Health is under attack in a way that it has never been before. Our health system has become a target and we have to  stop it.” 

In terms of NCDs, as such, this week’s meeting aims to muster a “coalition of the willing”, in the words of Ryan, as part of the lead up to the fourth high-level UN General Assembly meeting on NCDs, set for 2025. 

“We affirm our commitment to reducing the burden of NCDs in humanitarian settings and strengthening our emergency response at all levels, do joint efforts and leveraging our collective expertise,” Balkhy concluded.

“But at  times the solutions have less to do with medicine.. It has to do with diplomacy,” she added. “Once again, we do need peace.” 

Image Credits: Abdulsalam Jarroud/TNH, E. Fletcher/Health Policy Watch , Democracynow.org, UNHCR, WHO EMRO.