In Kenya, toxicologists and epidemiologists face a difficult choice: to pursue better-paid work to support their families, or volunteer as reviewers for vaccine clinical trials, often without the compensation needed to cover even their children’s school fees. Their dilemma underscores a broader challenge in Africa’s clinical research ecosystem. Slow, duplicative approval processes and limited regulatory […] Continue reading ->
Global malaria programmes have helped to save an estimated 14 million lives between 2000 and 2024, but growing drug resistance is threatening to undermine years of hard-won gains, a new World Health Organization (WHO) report has shown. Last year, the world recorded 282 million malaria cases and more than 600,000 deaths, with Africa accounting for […] Continue reading ->
Artificial intelligence could compress years of drug discovery into months – helping to overcome growing drug resistance to existing treatments for malaria and other vector-borne diseases. But scientists in low-income countries are often left behind. Jeremy Burrows, Medicines for Malaria Venture (MMV) vice president, head of drug discovery, explains how a new open-access, AI-powered drug discovery […] Continue reading ->
This week, the world marks World Antimicrobial Awareness Week and malaria parasites, though often forgotten, are part of the range of microbes preventing us from achieving the Sustainable Development Goal of Good Health and Well-being. Malaria remains an immense public health burden, especially in Africa. It mainly affects the poor, and remains an immense health […] Continue reading ->
The 97% cure rate for the novel compound, ganaplacide/lumefantrine in a recent Phase 3 trial offers hope for continued progress rolling back malaria even as resistance to artemisinin combination therapies (ACT) escalates.  A next-generation antimalarial drug GanLum (ganaplacide/lumefantrine, KLU156) slightly outperformed a standard of care Artemisinin Combination Therapy (ACT) in a recent Phase 3 trial […] Continue reading ->
There is an urgent need for a more comprehensive pandemic risk monitoring system that tracks threats and preparedness in real time, according to the WHO-hosted Global Preparedness Monitoring Board, in a report launched at the World Health Summit. This followed the release of a new World Health Organization data documenting the sharp global rise in […] Continue reading ->