Dr Mike Ryan helps attend to a health worker wounded in an attack in January 2019 against the Ebola vaccination team in the Democratic Republic of the Congo. The group, including Dr Tedros, were being evacuated by helicopter at the time.

The new Deputy Director General of the World Health Organization (WHO) is Dr Mike Ryan, who will assume the position alongside his current post as the executive director of Health Emergencies, Preparedness and Response.

Ryan, who succeeds Zsuzsanna Jakab, who retired in February, assumed the position on 1 April according to an internal staff communique send out last Thursday.

WHO Director General Dr Tedros Adhanom Ghebreyusus announced the appointment publicly on Monday at an event at the WHO headquarters, describing Ryan as “the general” and a “soldier”, and thanking him “for all his sacrifices”.

In 1990, Ryan, an Irish epidemiologist who trained as a trauma surgeon, went to work in a hospital Iraq that was being supported by the College of Surgeons in Ireland, supposedly for three months while he waited for his surgical residency to begin in Australia.

However, during that time, “Kuwait was invaded by Iraq, and we all became hostages in Baghdad”, said Ryan an interview with ‘Awake at Night’, a UN podcast series. Tragically, during this time he was injured in an accident involving a military convoy and stuck in Iraq with minimal treatment. This ended his career as a surgeon, resulting in him switching to infectious diseases.

“It was very clear to me that you were either a surgeon or a good infectious disease doctor because these seemed to be the two things [where] a doctor could make a difference in many developing country environments. So I went into infectious diseases and then ended up coming to WHO In 1996, to join David Heymann, who was setting up a new emerging disease programme in WHO,” Ryan explains. 

During this time, he worked on responses to a number of outbreaks including measles, Ebola (while based in Uganda), and other infectious diseases. Between 2011 and 2017, he worked on the Global Polio Eradication Initiative (GPEI) in Pakistan, Afghanistan, and the Middle East.

From 2017 to 2019, Ryan served as Assistant Director-General for Emergency Preparedness and Response in WHO’s Health Emergencies Programme.

In 2019, Ryan became Executive Director of Health Emergencies Programme, and one of the WHO’s public faces during the COVID-19 pandemic.

Image Credits: Lindsay Mackenzie/ WHO.

Baltazar Lucas, living with hepatitis B and a survivor of liver cancer who went through a liver transplant, goes for regular check-ups in Ortigas, Philippines.

There has been an increase in deaths from hepatitis B and C, the infectious viral liver diseases that kill as many people each year as tuberculosis – yet few people know that they are infected and get the treatment they need.

This is according to the World Health Organization (WHO) 2024 Global Hepatitis Report – the first to document epidemiology, service and product access – which was released on Tuesday at the start of the World Hepatitis Summit in Portugal.

New data from 187 countries show that the estimated number of deaths rose from 1.1 million in 2019 to 1.3 million in 2022.  Hepatitis B and C cause around 3,500 deaths every day.  

Around 83% the deaths were caused by hepatitis B, most commonly spread by mother-to-child transmission,  and 17% by hepatitis C, usually spread through contact with infected blood. While sexual transmission is also a route for hepatitis B transmission, this typically results in acute infections, which are, in fact, less life-threatening than the chronic infections that may be acquired in infancy and may lead to early mortality.

“Sexual transmission of hepatitis B usually results in an acute infection which is not life threatening.  This report is about chronic infections which often lead to early mortality from liver disease and cancer,” explained Cary James, CEO of the World Hepatitis Alliance.

“This is an important point as the misconception that chronic HBV is associated with sexual activity can be a major contributor to stigma within families, societies and health systems.”

WHO’s Dr Meg Doherty and report author Dr Francoise Renaud

“Hepatitis infection is a silent killer,” said Dr Meg Doherty, WHO’s Director of HIV, Hepatitis. “Awareness is very low worldwide. Most symptoms appear only once the disease has advanced, resulting in a huge volume of undiagnosed people living with hepatitis. Even when hepatitis is diagnosed, the number of people who go on to receive treatment remains low.”

According to the report, by the end of 2022 only around 13% of people living with chronic hepatitis B infection had been diagnosed and approximately 3% (seven million) had received antiviral therapy, while about 36% of those with hepatitis C, 36% had been diagnosed and 20% (12.5 million) had received curative treatment.

Almost two-thirds of global cases are concentrated in 10 countries –  Bangladesh, China, Ethiopia, India, Indonesia, Nigeria, Pakistan, the Philippines, the Russian Federation and Viet Nam.

Meanwhile, the WHO African region accounts for 63% of new hepatitis B infections, and yet only 18% of newborns receive the hepatitis B birth-dose vaccination. 

“Achieving universal access to prevention, diagnosis and treatment in these 10 countries by 2025, alongside intensified efforts in the African region, will be essential to get our response back on track,” stressed Doherty.

On the other end of the spectrum, Egypt has made huge strides to eliminate hepatitis C in particular.

“There are five main strains of hepatitis virus referred to as types A, B, C, D, and E. And in particular types B and C lead to chronic disease and together are the most common causes of liver cirrhosis, liver cancer and viral hepatitis related deaths,” she explained. 

Updated WHO estimates indicate that 254 million people live with hepatitis B and 50 million with hepatitis C in 2022.  Half the burden of chronic hepatitis B and C infections is among people 30–54 years old, with 12% among children under 18 years of age. Men account for 58% of all cases.

Treatment costs

Pricing disparities persist both across and within WHO regions, with many countries paying above global benchmarks, even for off-patent drugs or when included in voluntary licensing agreements.

“Despite the availability of affordable generic hepatitis medicines, many countries fail to procure them at these low prices,” said report author Dr Francoise Renaud. “Pricing disparities persist both across and within the WHO regions with many countries paying above global benchmarks, even for off patent medicines or when there are voluntary licencing agreements, which allow countries to produce or import generic formulations.”

For example, although tenofovir for treatment of hepatitis B is off patent and available at a global benchmark price of $2.4 per month, only seven of the 26 reporting countries paid prices at or below the benchmark. The lowest reported monthly treatment prices reported by countries ranged from $1.22 for 30 tablets in China and India to $34.20 in Russia.

Similarly, a 12-week course of pangenotypic sofosbuvir/daclatasvir to treat hepatitis C is available at a global benchmark price of $60, yet only four of 24 reporting countries paid prices at or below the benchmark.

The lowest reported price for a 12-week course of this treatment was from Pakistan at about $33 for a generic course of treatment, while the highest reported price was from China, at about $ 10,000.

About 75% of the reporting WHO focus countries rely primarily on government funding or out-of-pocket expenditure for
viral hepatitis diagnostics

Only 60% of reporting countries offer viral hepatitis testing and treatment services free of charge, either entirely or partially, in the public sector. Financial protection is low in the African region, where only about one third of reporting countries provide these services free of charge.

Correction (15 April, 2024). The original version of the story stated that hepatitis B infections are most commonly spread by sexual contact, when in fact the most common transmission route is mother to child transmission, according to WHO. 

Image Credits: Yoshi Shimizu/ WHO.

An artist's depiction of artificial intelligence.
An artist’s depiction of artificial intelligence.

Artificial Intelligence (AI) can save lives – but “we need to get the regulations right,” according to Dr Ricardo Baptista Leite, CEO of HealthAI, the agency responsible for artificial intelligence in health.

To address the urgent need for the robust regulation of AI in the healthcare sector, HealthAI has initiated a worldwide community of practice (CoP), the organisation said last week. This initiative aims to strengthen each nation’s capacity to create well-informed regulations that promote AI’s ethical and fair utilisation in healthcare.

“Our global community of practice is a critical platform for addressing the urgent need for regulation, bringing together global leaders from all sectors to ensure AI’s impact on health is positive, responsible and inclusive,” Leite said.

The CoP will be a platform for discussing AI in healthcare and sharing experiences with responsible AI use in this field. It will bring together organisations, policymakers, technology experts, and leaders in health AI, fostering potential collaborations.

“Since equity is core to our mission, we wanted to ensure a bottom-up approach be made to ensure the voices of all stakeholders from around the world would be heard as part of the development of these AI regulatory standards and in the implementation of these standards,” Leite told Health Policy Watch.

He said the CoP would be open to all institutions – public, private, academic, patient and community-based organisations, civil society movements and technologists – by application.

“We want to give a voice to those not heard as part of international processes and for us to be an important sounding board as we move forward and contribute to building this global ecosystem,” Leite added.

HealthAI has a three-year strategy implementation plan that focusses on identifying at least 10 pioneer countries that it can help support and provide technical assistance. Leite said one of the challenges in many countries is the “absolute absence” of any form of expertise at the regulatory level. “To be able to address this matter seriously in the future, countries will need to invest in developing that capacity.”

Leite noted that although organisations such as the World Health Organization (WHO), UNESCO, and the OECD are tasked with setting global standards, the countries must implement and apply these standards in practical situations.

The future of AI in healthcare (illustrative)
The future of AI in healthcare (illustrative)

Regulatory confidence in technology

There is a debate about whether regulations could hinder technology adoption in healthcare. However, Leite said HealthAI’s analysis is that many companies are hesitant to use technology due to concerns about legal liability in case of issues. His team believes establishing a regulatory framework will give companies the confidence to implement technology solutions.

HealthAI, including through its CoP, aims to create an online global repository of validated AI solutions. This platform will be open source and showcase approved technologies, their functions, and their compliance with ethical AI standards.

“This is especially important for startups in low- and middle-income countries,” Leite said. “Let’s say their national regulator just approved their technology. Now, suddenly, you can see their technology shown on this platform so that their innovations can be used in the Global North, meaning the tools developed in lower-resource settings could be a source of inspiration in high-income countries and not always the other way around.”

At the same time, Leite said, another global network goal would be establishing an early warning system. This system would detect unintended negative impacts of AI technologies worldwide, triggering a red flag for all agencies to take immediate action.

“This is important to ensure that governments can act in a timely manner and avoid harming citizens,” Leite said.

WHO Announces S.A.R.A.H.

HealthAI’s announcement about the CoP followed WHO’s announcement of S.A.R.A.H., a digital health promoter prototype with enhanced empathetic response powered by generative AI.

S.A.R.A.H stands for “Smart AI Resource Assistant for Health.”

“For too long health has often been viewed as a passive beneficiary of innovation rather than a driver of it,” wrote Hans Henri P. Kluge, WHO Regional Director for Europe in an article for Health Policy Watch. “It’s time to change this mentality and harness the power of innovation.”

S.A.R.A.H is an advanced AI resource assistant designed for healthcare. WHO said the tool incorporates the latest language models and cutting-edge technology to engage users round the clock in eight languages, covering a wide range of health topics across various devices. It will provide information on a number of health topics, including healthy habits and mental health, cancer, heart and lung disease, and diabetes.

“S.A.R.A.H gives us a glimpse of how artificial intelligence could be used in future to improve access to health information in a more interactive way,” said WHO Director-General Dr Tedros Adhanom Ghebreyesus.

Image Credits: Quick Creator, Pexels.

Sudanese women are being targeted by soldiers using rape as a weapon of war.

The “weaponization of sexual violence” during conflicts is a major challenge facing the health sector, and it needs the serious attention of the international community, said World Health Organization (WHO) Director General Dr Tedros Adhanom Ghebreysus.

Tedros broke down  while recounting that his own cousins had been raped and his uncle had been killed during recent violence in Tigray in Ethiopia as gender-based violence has become an instrument of war.

“Tens of thousands of women have been raped during that conflict, and there is no capacity in the region or within WHO to handle it. But you see it not only in Ethiopia, but you see it in DRC, you see it in Haiti, you see it in Sudan. You see it everywhere,” said Tedros during a  high-level dialogue with UN High Commissioner for Human Rights Volker Türk in Geneva on Monday – a day after International Health Day and the WHO’s 76th anniversary.

Tedros admitted that addressing gender-based violence was “beyond the capacity” of the WHO.

“I say beyond our capacity, or beyond the capacities of any player I know in conflict,” said Tedros.  “Many thousands of women haven’t received any services whatsoever – nothing, zero – and it’s the same in many countries where there is active conflict,” said Tedros.

“The magnitude is so high, and the international community should take it seriously,” he stressed, adding that women didn’t just need medical services, but psychosocial support.

Strategic dialogue with OHCHR

UN High Commissioner for Human Rights Volker Türk recalled that a number of countries, including Sudan, denied that their soldiers were involved in rape “but it happens in every army”.

Türk proposed a strategic dialogue between his Office – known as OHCHR – and the WHO to address human rights in the health sector and how to secure the right to health.

The two organisations have a framework of cooperation, said Türk, but they hadn’t been able to “bring it to the next level” during the pandemic.

“I think it would be good to take stock, and look strategically at how both worlds can be much closer together on a number of fronts,” he proposed – with Tedros immediately agreeing to a meeting during the course of the year.

 

The two leaders also raised the deliberate targeting of health facilities during conflict and the impact of this on health workers, and the high fatality rates of civilians in current conflicts. The WHO has documented the destruction of 300 health facilities and the deaths of 742 health works in this year alone.

Türk said that after “two massive world wars, after atrocity crimes, horrible war crimes, the Holocaust, and the Great Depression, there was a real recognition that, when it comes to health in conflict, hospitals and medical personnel are sacrosanct”.

But this has been replaced by a “flagrant blatant disregard for the laws of the war when it comes to hospitals and medical personnel”, he added.

In Syria, Ukraine and Gaza, there had been an almost deliberate targeting of hospitals and of health personnel, said Türk, who described what is happening in Gaza as “an unmitigated disaster” with “hardly any health facilities working”.

“We need to regain the space of the normative values that go back to the origins of why it is important to protect healthcare personnel, and health infrastructure in all situations around the world. I mean, we are talking about 55 active conflict situations,” he added.

‘Target fossil fuel’

The two leaders also raised the impact of changing climate on health, with Tedros supporting the focus on phasing out the use of fossil fuels, which is responsible for “70% of greenhouse gases.

“Because of climate change, asthma is on the increase. Cardiovascular diseases are on the increase. Vector borne diseases like malaria, dengue are actually invading places they have never been known before,” said Tedros.  

Dr Tedros Adhanom Ghebreyesus

“Universal health coverage is a question of rights, and it has to influence the budgetary decisions that states make, and which brings us to the issue of the human rights economy,” said Türk. 

“If there was any lesson to be learnt from a COVID pandemic, it is precisely that it is that you need to have universal health coverage in order to be able to deal with the big challenges or the stress factors that a pandemic can unleash,” he added.

“We want to be sure that we’re prepared for whatever comes next, and universal health coverage is absolutely critical, both in terms of rights, but also in terms of sustainable development for any country in the world.”

Image Credits: CC.

WHO and UN agency officials survey the ruins of Al-Shifa’s Emergency Department during a visit Friday, April 5.

Speaking out on World Health Day, WHO Director General Dr Tedros Adhanom Ghebreyesus decried the destruction of Gaza’s Al-Shifa hospital and blamed Israel for the devastation, saying that the “atrocity” of the Hamas attacks on Israeli communities 7 October, did not justify “the horrific ongoing bombardment, seige and health system demolition by Israel in Gaza.”

He made his remarks Sunday, two days after the first WHO visit to Shifa Hospital following the 1 April withdrawal of Israeli forces from the hospital compound after a fierce two-week battle with Hamas forces in and around it.

“It has been six months since the brutal attacks in #Israel by Hamas and other groups, in which 1,200 people were killed, many more injured and hundreds abducted,” Tedros said in a post on X, of the 7 October events that triggered the war. 

@WHO once again condemns this barbaric act of violence and demands the release of remaining hostages. However, this atrocity does not justify the horrific ongoing bombardment, siege and health system demolition by Israel in #Gaza, killing, injuring and starving hundreds of thousands of civilians, including aid workers.

“The deaths and grievous injuries of thousands of children in Gaza will remain a stain on all of humanity…. The denial of basic needs – food, fuel, sanitation, shelter, security and healthcare – is inhumane and intolerable,” said the director general. 

Images of the hospital taken during the UN inter-agency visit, which included WHO, OCHA and other relief organisations, highlighted the degree of damage done, with the hospital’s emergency surgical and maternity departments, in particular,  reduced to unrecognisable shells.

“As WHO marks World Health Day … under the theme ‘My health, my right,’ this basic right is utterly out of reach for the civilians of Gaza,” said a WHO statement shortly after the mission took place, noting that prior to the beginning of the war, Shifa had been the largest and most important referral hospital in Gaza.

“Of the 36 main hospitals that used to serve over 2 million Gazans, only 10 remain somewhat functional, with severe limitations on the types of services they can deliver,” said the WHO statement, noting that “access to health care in Gaza has become totally inadequate, and the ability of WHO and partners to help is constantly disrupted and impeded.

“The proposed military incursion into Rafah can only result in further diminution of access to health care and would have unimaginable health consequences.  The systematic dismantling of health care must end.”

The WHO comments on Shifa triggered a sharp reaction from Israel’s ambassador in Geneva, Meirav Eilon Shahar, who accused WHO of “complicity” in its silence over Hamas militarisation of the hospital that Israel says triggered the two-week invasion in which several hundred Hamas gunmen, including a number of senior Hamas leaders, were reportedly killed.

“It’s not just the 133 men, women and children which are held hostage by Hamas, it’s the entire Palestinian civilian population and their infrastructure including hospitals and schools,” said Shahar in an X post.

Hundreds of terrorists in Shifa. Silence. Hostages taken to hospitals on October 7. Silence. Weapons found in incubators. Silence. Rockets founds in wards. Silence. The last 6 months. Silence from @WHO on Hamas, and its abhorrent strategy. Silence is complicity.”

World Health Day, celebrated every year on 7 April, marks the anniversary of the founding of the World Health Organization in 1948.

Image Credits: OCHA .

Ukrainian family flees over the border on foot in March 2022, following Russia’s invasion of the country.

Victims of conflict face a double or triple whammy when trying to cope with mental health challenges. Even the most resilient may begin to experience symptoms of anxiety, anger and sleeplessness during wartime that last decades. And those with pre-existing conditions are forced to cope with the acute trauma provoked by experiences of death, destruction and displacement at the same time as any chronic condition, for which they may be unable to get medications or support. 

The issue was the focus of a recent online eventNo Peace of Mind” organised by the Global Health Centre of Geneva’s Graduate Institute and the UK-based charity Beyond Conflict, in which experts with experience dealing with ongoing conflicts in Ukraine, Kashmir and the Palestinian West Bank and Gaza spoke about the myriad of challenges they faced. 

Mental health alongside physical care in emergency settings

Mariana Duarte, Médecins Sans Frontières (MSF)

Panellists emphasised the need for health and humanitarian relief organisations to recognise the need to provide mental health support to conflict-affected populations, along with other emergency health services. 

In prolonged conflict settings, long-term investments in culturally sensitive and accessible care are important, they stressed. Building awareness about self-care as well as more training for family practitioners in the identification and treatment of mental health conditions can help overcome the dearth of resources, as well as building more resilient community services that also counter-balance the historical focus on hospital-based care.  

“We cannot allow a lack of resources to be an excuse for neglecting the basic needs of people who are suffering,” said Mariana Duarte, a mental health advisor to Médecins Sans Frontières (MSF). 

“Integrating mental health into emergency response requires collaboration amongst various sectors including health, social services, education and community organisations,” she stressed. 

At the same time, she added, the responsibility of health actors does not end with the provision of services.

“We must also address the underlying cause of armed conflicts and work tirelessly to promote peace, justice, and reconciliation.” Duarte said. “Only by addressing the roots of conflict, can we hope to create a world where mental health is protected and valued.”

Addressing mental health after the conflict ends  

Edna Fernandes, co-founder Beyond Conflict

If war- related traumas are not resolved, then they continue to create illness long after the hostilities have ended, noted Edna Fernandes, the co-founder of the charity Beyond Conflict and moderator of the session. 

She helped found the organisation after  life-changing interactions with two refugees from Iraq who fled Islamic State in 2016.  One was a young woman that she met at an IDP conference in the United Kingdom who had escaped sex trafficking but remained “full of rage.” 

“When I asked her privately what was the one thing that would make a real difference, she surprised me because she said ‘we simply need more psychiatry.’”  

The second was an 10 year-old boy who had escaped ISIS and after three months in an IDP camp, barricaded himself into a room with two small children ages 2 and 3, which he then hanged.  

“So the 10-year-old was repeating the cycle of terror and violence that he had learnt from ISIS,” she said. “Through these two refugees, we first learnt about the lack of mental health support for victims of war and conflicts around the world.”  

Since being founded in 2018, the charity has worked with Rohingya refugees from Myanmar living in Bangladesh;  Ukrainian refugees, and since January, a project for Palestinians in the West Bank and for Israeli young people who were traumatised by the 7 October Hamas attack on the Nova Music Festival.  

“In all cases, we support expert partner organisations on the ground who know the cultural landscape inside out”,” she said. “Yet despite growing awareness and an understanding of the long term cost of failure to address more related trauma, the huge demand for mental health support remains largely unmet.”  

Psychiatric conditions exacerbated during acute crises  

Displaced Palestinians walk from the north of Gaza towards the south in January 2024 after Israel ordered their evacuation during its war on Hamas.

Expert panellists from Ukraine; Jammu and Kashmir, and the Palestinian West Bank, provided their insights into mental health trauma in three conflict-ridden parts  of the world.  

“Presently, the only psychiatric hospital in Gaza has been ravaged by war,” said Mohammad Marie, an assistant president at An-Najah’s College of Medicine in the West Bank city of Nablus. He described the urgent challenges faced in an active conflict setting, where life-threatening threats to physical health create new mental health scars that add to those previously experienced.  

“Psychiatric patients in Gaza are living without medication,” he declared. “But in addition, children’s [limbs] are being amputated without anaesthesia; women are undergoing caesarean sections. 

“This catastrophic situation leads to death, or people live with mental health scars for the rest of their life,” he said. “There is no mental health care in Gaza. There is no medication, especially psychiatric medication. In Gaza. In addition to that, there is no food, no clean water.” 

And even amongst Palestinians in the West Bank, where Marie lives, the war has changed their lives, as the Israeli military occupation around them tightens its grip. 

“I live in Nablus, for example, and personally I have been unable to move outside of my city for the past six months. I feel suffocated, unable to travel,” he said.  

In both the West Bank and Gaza, decades-long waves of conflict, along with the accompanying feelings of helplessness and hopelessness,  have left people in an unending cycle of intergenerational trauma, he added. 

“And each trauma is more difficult or more severe than in the past.” 

When the bombs stop falling the real struggle of people starts 

Saiba Varma, bottom left, describes particularly vulnerable population in the Jammu Kashmir context.

Sometimes it can feel very difficult to talk about mental health in the context of conflicts, added Saiba Varma, an associate professor of psychological and medical Anthropology at the University of California, San Diego.  

“It makes you sometimes question why is this important given what people are going through?  But I have to always remind myself that it’s what happens after the bombs stop falling,” Varma said. “That’s when, in many ways, the real struggle of people starts. And as an anthropologist, when I’m thinking about the relationship between mental health and war and occupation.” 

In complex and ongoing long-term conflicts, the “war on the psyche” persists even if bombs are not falling every day, she explained. 

“It is a war that targets people’s perceptual reasoning, decision making and behavioural capacities. It is very explicitly a war that does not only target soldiers and combatants, but ordinary citizens,” Varma continued. “For example, in the region of Jammu and Kashmir, the Indian government does not see it as an ongoing occupation. It does not see it even as a war. It sees it as a place of terrorism, whereas when you talk to people from Jammu and Kashmir they will name this as a war, as an occupation.

“So even the ways in which we name these conflicts are imbued with ambiguity. That, I think, is a sort of psychic assault on people’s ability to reason and make sense of their world. That’s where it really begins, in terms of the mental health challenges that are particular to Kashmir but certainly not unique.”

Varma noted that a lot of research on trauma and PTSD is based on people who have fled places of violence. However, in places like Kashmir, the population continues to live in the traumatic environments.

“Amongst the vulnerable populations in Kashmir, as in other conflicts, we’re seeing very high rates of substance use in children and youth,” Varma said. “In women, we’re seeing increased rates of self harm.  And  particularly what we’re seeing more recently are the ways in which political activists, journalists, medical professionals and others are being criminalised for speaking out and they’re actually called narrative terrorists by the Indian government. So that has a unique kind of set of mental health challenges as well.”

And care is either deliberately targeted or eroded over time due to the effects of militarisation, she added.

“In terms of, you know, who can access a hospital, what kinds of medications are available? Is there a curfew, is there a strike?”

Challenges faced by humanitarians 

WHO officials in northern Gaza mission in early March – attending to the physical needs of people trapped in conflict tends to overshadow mental health.

The complex of issues leaves humanitarian organisations with huge challenges in terms of how critical they choose to be about the underlying political or conflict dynamics while also trying to gain access to conflict settings where help is most needed. 

And even when services might be available, relief organisations must address stigma around getting care for mental health issues, Varma added.  

“There’s a lot of apprehension people have towards particularly biomedical Western medical psychiatric care that has to do with histories of abuse in psychiatric institutions.  It was only in 2001 that the Indian Supreme Court banned the use of restraints in psychiatric hospitals. So that’s very recent, and people remember those histories and that contributes a lot to their apprehension and seeking care.”

Finally, she said, humanitarian mental health care is inevitably limited in scope. 

“It’s not always able to provide health and mental health in the way in which local populations understand it. And in the case of Kashmir as with many other places in the world, people define health much more broadly than just being about the absence of symptoms. For them health has a social dimension, moral, spiritual, psychological and political. 

“I think the thing that I heard most often from people while I was doing my research was this idea that we will not be healthy until the conflict leaves us.”

At the same time, intervention strategies need to include more focus on the cultivation of positive survival skills, she said. 

“I think we need a lot more focus on the positive aspects of how people living in these contexts survive. So some of the things that I heard from people in Kashmir were for example, patience, cultivating patience, forbearance, hospitality, these are kind of critical coping skills that I think need a lot more attention…  So, all of those dimensions will also require attention from humanitarian organisation.” 

Countering stigma in Ukraine

Ukrainian child with his dog, displaced by war, in a refugee camp on the Moldova-Ukrainian border.

Ukraine, as well, also faces historical and cultural barriers to mental health care, with stigma persisting amidst a historical lack of resources, observed Dmytro Martsenkovsky, assistant professor at the  Department of Psychiatry of Bohomolets National Medical University, Kyiv. 

“Ukraine has inherited a Soviet-based type of mental health care, and it was very institutionalised,” he said. 

So basically, if people needed mental health services, hospitals were almost the only place people could access support, he said. 

But with civilians under heavy bombardment and confined to shelters, accessing hospitals became logistically more difficult, even as mental anxiety and related disorders grew exponentially. Moreover, more than 10 million people were displaced, saw family members killed, or experienced torture and imprisonment under various waves of Russian occupation.    

In addition, there is a lack of “mental health literacy” in Ukrainian society, with considerable stigma, he said.   

“It has some historical roots, but also a lot of people are afraid because, for them, seeking mental health services is showing that you’re weak, that you’re not able to cope with your conditions on your own,” Martsenkovsky said. 

Countering that, Ukraine’s First Lady, Olena Zelenska, has championed a more open approach to mental health treatment, supported by a broad-based mass media campaign. 

An online “How are You” platform has been developed that provides basic information on mental health and self-care techniques. 

“And this can help people who are feeling anxious or fear to seek professional care, to receive at least basic interventions to try to cope with their conditions,” he said. 

Martsenkovsky is also working with the Ministry of Health to provide more education to family doctors on basic mental health interventions. 

“And this is one of the core priorities because we had a lack of human resources even before the war,” but with the invasion most of the specialists, especially those who were women, were either displaced or left the country with their own children seeking safety and shelter.”

Recovery may take decades

Whether it’s Gaza, Ukraine or elsewhere, panellists all agreed that it typically takes “decades” for people to recover from the psychological trauma of war, particularly when the conflict also persists with no end in sight.  

“We are talking about … creating the possibility to enjoy life again, to have proper sleep, to not wake up from nightmares, to work for the prosperity of families and communities and to have a stable belief in a safe future,” Martsenkovsky said. “Because the longer the conflicts go on, fewer and fewer people are able to see a future for themselves and their children. It becomes more difficult for them to cope with everyday challenges.

“I’m not talking about the challenges of war, but about conflicts in families, financial difficulties that all of us face at points in time. And this will affect those who are traumatised by war for many decades … sometimes for generations.” 

Image Credits: © UNRWA/Ashraf Amra, People in Need, WHO , UNICEF/UN0599222/Moldovan.

Microplastics have been found in the arteries .

Doctors and scientists are concerned about the impact of plastics, not only on the environment but on human health – and new research has found a potential link between microplastics and heart attacks and strokes. 

When plastics enter the environment, humans may inhale or ingest them. Moreover, just as plastics can take centuries to break down on earth, plastics do not easily break down within our bodies, potentially leading to accumulation over time.

Multiple studies have already detected microplastics in various organs, from the lungs to the placenta.

The newest study, published in the New England Journal of Medicine last month, involved more than 250 people who had carotid artery disease and were having surgery to remove the build-up of plaque from their carotid arteries, the main arteries that supply the brain with blood, located in the neck. 

More than half (58%) of these patients had microplastics or even smaller nanoplastics in a main artery, and those who did were 4.5 times more likely to experience a heart attack, a stroke or death in the approximately 34 months after the surgery than were those whose arteries were plastic-free.

The researchers collected plaque samples from 257 patients during their surgeries and performed a chemical analysis on them. They found that 150 had microplastics and nanoplastics in their arterial plaque, mainly polyethylene (in all 150 people) and polyvinyl chloride (in 31). 

These are two of the most commonly used plastics in the world; the researchers looked for 11 plastics.  

Polyethylene is usually used for packaging, such as plastic bags or containers. Polyvinyl chloride is a more versatile plastic used for anything from medical devices to window frames and flooring.

In addition to the increased risk of heart attack or stroke, the researchers also found that those with microplastics in their plaque samples had higher levels of biomarkers for inflammation.

However, the researchers pointed out that individuals with microplastics in their plaque also exhibited other risk factors such as smoking, high cholesterol, diabetes, and heart and circulatory diseases, all of which elevate the risk of heart attack and stroke to begin with. 

Moreover, since all of the study participants were already undergoing carotid artery surgery and were known to have carotid artery disease, it is too early to tell whether the results of this study can be generalized to a broader population. 

In addition, the researchers stressed that the study does not prove that microplastics cause heart attack or stroke, only that there is a potential relationship. 

Dr Steve Nissen, a heart expert at the Cleveland Clinic, told The Independent that while “the study is intriguing,” it has “substantial limitations.” 

He said, “It’s a wake-up call that perhaps we need to take the problem of microplastics more seriously. As a cause for heart disease? Not proven. As a potential cause? Yes, maybe.”

Cardiac function 

This is not the first study to examine the link between plastics and human health. A similar, separate study published earlier this year in Environment International also examined the effect of microplastics and nanoplastics on the cardiovascular system, finding that these plastics “affected cardiac functions and caused toxicity on (micro)vascular sites.”

Effects included abnormal heart rate, cardiac function impairment, pericardial edema, and myocardial fibrosis, as well as hemolysis, thrombosis, blood coagulation, and vascular endothelial damage. 

This latest study comes as global representatives, led by the United Nations Environment Programme (UNEP), are working to finalize a plastics treaty to help eliminate plastic pollution by the end of the year.

The fourth session of the Intergovernmental Negotiating Committee to develop an international legally binding instrument on plastic pollution, including in the marine environment (INC-4), is scheduled to take place from 23- 29 April in Ottawa, Canada

Image Credits: University of Oregon.

The Lady Health Worker programme in Pakistan have helped to double the child vaccination rate.

Each woman in the health workforce is powerful, capable of transforming individual lives, communities, and nations when supported in her role. Women health workers deliver care to approximately five billion people, mostly as nurses, midwives, and community health workers. They contribute $3 trillion to global health annually, half in unpaid work. 

Despite constituting 70% of the global health workforce, they often serve in low-status jobs, with little or no pay. Men hold 75% of health leadership roles and, on average, earn 28% more than women. Investing in these women is a smart move, offering an estimated 9:1 return on investment and contributing to women’s economic empowerment.

This World Health Worker Week (1-7 April), and ahead of the Africa Health Workforce Investment Forum in May, we call on governments and the global health sector to recognize the transformative contributions of women in the health workforce by developing and implementing policies to ensure their protection, pay, and promotions.

Immense potential of women in health

Women health workers play a dual role, improving health outcomes while advancing gender equality by serving as role models in societies where women’s participation is limited.

 Studies indicate that promoting gender equality within communities not only fosters economic growth but also enhances access to contraception and reduces child mortality. Moreover, these workers significantly contribute to economic prosperity by serving as frontline caregivers in rural areas with inadequate health infrastructure, promoting sexual and reproductive health and rights, and investing in the health and education of their families.

The World Economic Forum predicts that by 2050, the climate crisis will result in 14.5 million more deaths and $12.5 trillion in economic losses, with an additional $1.1 trillion in costs to health systems.  

Women and children will bear the biggest burden, highlighting the urgent need for women health workers to play a crucial part as part of a broader multidisciplinary effort in educating communities, supporting the delivery of healthcare in challenging conditions, and advocating for policies that mitigate the health impacts of climate change. As most of the health workforce, they can respond to climate-induced health emergencies like the rise in infectious diseases, the effects of extreme heat on pregnant women, and the rise in waterborne disease. 

Saving lives in Pakistan and Nigeria

Women health workers can help achieve universal health coverage, and foster stable, prosperous societies through global health security. This potential holds true everywhere.

For example, Pakistan and Nigeria – despite their unique cultures, politics, and economies – face similar challenges such as rapid urbanization, weak rural health care, high maternal and child mortality, extreme vulnerability to climate change, and gender inequalities. Ensuring we protect, support, and invest in women health workers is a high-impact solution.

Lady Health Workers (LHW) and community midwives in Pakistan, through initiatives like the Pathfinder ‘building healthy families’ program, provided critical support during the 2022 floods when a third of the country was under water. 

LHW canvassed districts in Sindh Province, reaching communities with 20,000 dignity kits for safe pregnancies, and information on nutrition, hygiene, and health, easing the floods’ toll. 

Midwives delivered babies at birthing stations that replaced flooded health clinics.  LHWs also played a crucial role during the COVID-19 pandemic, providing vital information on infection prevention and supporting isolated women at risk with information on gender-based violence services. 

Since 1994, when the LHW program began, these workers have contributed to the number of fully vaccinated children nearly doubling. They have helped to cut maternal and newborn deaths and increase family planning access.

A Nigerian mother and her baby who benefited from the Saving Mothers Giving Life programme

Similarly, Community Health Extension Workers (CHEWs), nurses, and midwives in Nigeria—mostly women—have saved numerous lives, through programs like Saving Mothers Giving Life. 

In Cross River State, CHEWs provided emergency obstetric and newborn care services in rural communities and referred complicated cases to higher-level health facilities leading to a 66% decrease in maternal mortality in supported health facilities over three years. 

In Akwa Ibom state, CHEWs learned how to offer clinical contraceptive methods—injectables and implants—at local health facilities, and within two years of the training, uptake of modern contraceptives doubled while the number of women with contraceptive implants tripled.

What we need to do now

Investing in women in the health workforce fosters health, development, and prosperity. To maximize this investment, we must protect, pay, and promote women, formalizing their roles within health system strategies, plans and budgets, and providing adequate training and mentorship from higher level providers. 

We must elevate women into leadership positions, ensuring they are involved in budget planning and on emergency response committees, and support them with woman-friendly policies like maternity leave, childcare support, and protection against workplace harassment and discrimination. We must ensure they receive a fair wage. Without these investments, the power of women in the health workforce will be a missed opportunity.

Dr. Tabinda Sarosh is Pathfinder’s President in South Asia, Middle East, and North Africa. She is accountable for the impact and performance of Pathfinder’s programs in Bangladesh, India, Egypt, Jordan, and Pakistan. 

Dr. Amina Aminu Dorayi is Pathfinder’s Country Director in Nigeria. She has extensive experience designing and managing health system and sustainable development programs seeking to improve the health of women, girls, and communities.

 

Image Credits: Women Deliver, Pathfinder.

Afghan opium poppy cultivation sustains many rual communities – and keeps many in the adiction vicious cycle

The ‘forgotten crisis’ of Afghanistan has exposed more and more young Afghans to mental health problems and drug abuse amid dwindling donor support and crumbling healthcare under the Taliban regime, said experts at a high-level side event at the recent meeting of the Commission on Narcotic Drugs in Vienna Austria.

Since the Taliban imposed a drug ban in April 2022, opium poppy cultivation in the war-ravaged country has dropped by around 95%, according to the United Nations Office on Drugs and Crime (UNODC)

But experts claim that drug abuse, particularly among the youth, is getting worse – and is being compounded by a lack of treatment.

The WHO estimates that around 2.9 million people abuse drugs in the country, while nine million have mental health issues in a population of around 38,3 million.

Holistic approach

At the side-event on “Mental health and substance use disorders in Afghanistan”, hosted by the World Health Organization (WHO), UNODC, the European Union (EU) and the Japanese government, stakeholders said the rapidly deteriorating socio-political environment in the country poses new challenges that require a more holistic approach and engagement with the Taliban authorities to save millions of lives. 

Jean-Luc Lemahieu, UNODC’s director of policy analysis and public affairs, said that many youngsters trying to escape the Taliban’s oppressive system of governance are vulnerable to drug abuse and exploitation, including radicalization.

To confront those threats, a system of community-based programmes anchored around existing primary health care services, should be developed, he and other experts speaking at the session emphasized. Those need to address both drug addiction and offer “active livelihood support and vocational skill training.”

Opium poppy farming in Afghanistan dramatically decreased after a 2022 drug ban.

UN officials noted that the “near-total contraction of the opiate economy is expected to have far-reaching consequences” for rural communities who relied on income from cultivating opium.

“Farmers’ income from selling the 2023 opium harvest to traders fell by more than 92 per cent from an estimated $1,360 million for the 2022 harvest to $110 million in 2023,” according to UNODC.

The WHO estimates that 23.7 million Afghan people will need humanitarian assistance this year as economic conditions in the country deteriorate. In addition, 9.5 million people have no or very limited access to healthcare.

Experts at the event warned that mental health and drug addiction can have far reaching public health consequences, including higher mortality rates, infectious diseases like HIV, hepatitis as well as diminished productivity.

Social tensions

Raffaella Iodice, Chargée d’Affaires and deputy head of the EU Delegation to Afghanistan, told the conference that mental health issues and drug addiction can trigger social tensions and negatively influence stability in communities. 

“Investing in drug demand reduction and mental health, quality, evidence-based and comprehensive treatment and prevention can pave the way for more sustainable and resilient communities that are critical for advancing the overall economic situation,” she said.

The EU is supporting a 100-bed Female and Children Drug Addiction Treatment Centre (DATC) in Kabul, which was established in December 2023.

It assists mothers and children up to the age of 17, offering “child counselling sessions that surpass conventional education, acting as a crucial pillar of support for young minds navigating the complexities of addiction”, according to a report from the WHO EMRO region

Expanding outpatient services at primary health care level

Abdul Hakim, who was enrolled in a drug addiction treatment centre in Kabul eight months ago after 20 years of drug addiction,  told Health Policy Watch that the easy availability of drugs was one of main reasons why many return to addiction after treatment and recovery.  

“If the authorities collect the drugs and dealers from the market, we will recover and stop using drugs,” he said.

Kabul city resident Gholam Ali, whose son became addicted to drugs eight years ago, told Health Policy Watch that his son has been treated several times, but easy access to drugs has made him addicted to it again. 

“There was no clinic left that I did not take my son to. He is treated for one or two months in each clinic, but when he leaves the clinic, there are drug addicts and drugs available outside, and he turns to drugs again,” said Ali.

Anja Busse, a UNODC programme officer working on prevention, treatment and rehabilitation,  said that the treatment model that exists in Afghanistan right now, based around clinics in large cities, is unable to meet the needs in the sprawling country, where rural needs are neglected. 

“The outpatient services in the community would need to be widely expanded and to be integrated in the community based health care approaches to have a continuum of care,” said Busse.

“ The reduced availability of previously widely used opioids at local markets has potentially increased risks for people with drug dependence due to increased levels of police interactions.”

Afghanistan’s health system system has been struggling to meet mounting demands amid dwindling aid and restrictions. Stigma is also a problem.

“Whether we are facing a mental health patient or substance use disorder client, we are facing a major stigma issue and most of the communities,” said Dr Vail Al-Raas, the mental health and psychosocial support coordinator at the International Medical Corps in Afghanistan.

She suggested the mental health treatment programs should be integrated into existing public health primary care programmes to use existing infrastructure and resources. 

“This can give [these programmes] a good chance to expand and be implemented on the ground, and interest has recently been shown by some donors.”

Image Credits: Resolute Support Media, UNODC.

The new generation of obesity drugs have reached sky-high popularity – and command high prices.

Demand for diabetes drugs such as Wegovy, Ozempic, Rybelsis and Trulicity has soared since they have been clinically proven to help weight loss – but they are massively overpriced in the US and unavailable in most low- and middle-income countries (LMIC), according to Médecins Sans Frontières (MSF).

The mark-up for these drugs – called glucagon-like peptide 1 agonists (GLP-1) – in the US is almost 40,000%, according to a paper published in JAMA last week authored by Yale University’s Dr Melissa Barber and MSF’s Dr Dzintars Gotham, Dr Helen Bygrave and Christa Cepuch.

The authors modelled the manufacturing costs of a variety of diabetes medications and added a modest profit margin.

“MSF’s study estimates that GLP-1s for diabetes could be sold at a profit for just $0.89 per month, compared to the price of $95 per month charged in Brazil, $115 per month charged in South Africa, $230 charged in Latvia and at least $353 charged in the US [based on Medicare price], which is a 39,562% markup over what the estimated generic price could be,” according to MSF’s press release. In fact, the US drug costs are usually much higher, reaching as much as about $1000 monthly.

Novo Nordisk makes both Ozempic and Wegovy (which contains a higher dose of the active ingredient, semaglutide, than Ozempic), while Eli Lilly makes Trulicity. Some are oral pills and others are injections.

US Senator Bernie Sanders has called on Novo Nordisk to lower the price of Ozempic Wegovy in the US to no more than what they charge for this drug in Canada.

“The American people are sick and tired of paying, by far, the highest prices in the world for prescription drugs while the pharmaceutical industry enjoys huge profits,” said Sanders in a statement.

“As a result of a major grassroots movement, Novo Nordisk did the right thing by recently reducing the price of its insulin products by some 75% in America. Novo Nordisk, a company that made nearly $15 billion in profits last year, must now do the right thing with respect to Ozempic and Wegovy,” added Sanders, who chairs the US Senate Health, Education, Labor, and Pensions Committee.

FDA approval for weight management

While GLP-1 drugs were made to treat diabetes, in 2021 the US Food and Drug Administration (FDA) approved Wegovy for weight management in people with a body-mass index (BMI) of over 30, or a BMI of over 27 with underlying conditions such as high blood pressure.

“Novo Nordisk and Eli Lilly are the only producers of these GLP-1s today, and their intellectual property barriers on the drugs and injection devices block any generic manufacturing that could help drive prices down,” MSF notes.

“The corporations have not even announced a price for low- and middle-income countries, nor have they licensed these drugs so that generic manufacturers could make them, which would help to meet global demand and drive prices down,” MSF says, noting that because they are now being used for weight loss in high-income countries, the companies are “unable to meet the massive demand”.

Co-author Christa Cepuch, pharmacist coordinator at MSF’s Access Campaign, describes the new drugs as “an absolute game changer for people living with diabetes”, but cannot be accessed by people in LMICs.

“Eli Lilly and Novo Nordisk can in no way supply the world with the amount of these medicines needed to meet global demand, so they must immediately relinquish their stranglehold and allow them to be produced by more manufacturers around the world,” said Cepuch.

The steep price of the drugs is hampering access even in the US, although the country’s federal health insurance programme, Medicare, recently struck a deal with Novo Nordisk, to cover the cost of Wegovy – but strictly for preventing heart attacks and strokes not for weight loss, Reuters reported

“The American people are sick and tired of paying, by far, the highest prices in the world for prescription drugs while the pharmaceutical industry enjoys huge profits,” said sen. Bernie Sanders, Chairman of the Senate Committee on Health, Education, Labor, and Pensions on the US cost of GLP-1s.

“Ozempic has the potential to be a game changer in the diabetes and obesity epidemics in America. But, if we do not substantially reduce the price of this drug, millions who need it will be unable to afford it,” he continued.

Obesity’s heavy burden

The GLP-1 drugs stimulate insulin production and feeling of satiety (fullness), promote weight loss, lower blood pressure and cholesterol, improve blood flow in the heart and uptake of glucose in the muscles, according to the US National Institute of Health.

Side effects can include commonly nausea, diarrhea, vomiting, constipation, stomach pain, headache or stomach flu, and less often, depression with suicidal thoughts or kidney failure.

Doctors warn that they need to be taken alongside a healthy diet and exercise.

The US accounts for almost three-quarters of the sale of Novo-Nordisk’s Ozempic, Wegovy and Rybelsus, according to Pew Research Center. The country has an adult obesity rate of 42%, according to the American CDC, one of the highest in the world.

Despite steep prices and side-effects, GLP-1s have become wildly popular in the last few years, especially in the US. 

Obesity is a growing problem worldwide, affecting 890 million adults – 16% of the global population – in 2022, according to the World Health Organization (WHO). The prevalence of this condition more than doubled between 1990 and 2022.

Global costs of obesity and overweight are predicted to reach $3 trillion per year by 2030 and more than $18 trillion by 2060 at the current rate.

In relation to obesity, World Health Organization (WHO) Director General Dr Tedros Adhanom Ghebreyesus recently stressed that the private sector “must be held accountable for the health impacts of their products” as Health Policy Watch reported – a reference to the impact of products such as ultra-processed food and sugary drinks on obesity.

Being overweight and obese increases people’s risk for type 2 diabetes, heart disease and cancer, WHO highlights, also affecting bone health and reproduction and increase the risk of certain cancers.

Both conditions can be affected by gene composition, but are mostly a result of an imbalance of energy intake (diet) and energy expenditure (physical activity). As such, are largely dependent on the options the environment offers. 

“Obesity is a societal rather than an individual responsibility, with the solutions to be found through the creation of supportive environments and communities,” WHO says.

The analytics platform, Airfinity, argues that it would be beneficial for public health to administer Wegovy to not only to diabetics type 2 patients, as the current Medicare deal allows, but to all people in the US with a BMI over 40. 

If 60% of people living with obesity and 40% of those of a BMI above 35 received the drugs, this could prevent as many as 300 000 heart failures in the US by 2030, according to Airfinity

World distribution of obesity. Safe the extreme numbers for small populations (on the right), some Middle Eastern countries and the US show highest percentages.

The demand for the Novo Nordisk drugs has more than quadrupled between 2019 and 2021, reaching 8.2 million prescriptions.

In fact, the demand was so high that it caused many months of shortages in the US, making it difficult for many to obtain their doses, Reuters reports.

Even those who do not have any medical reason to take GLP-1s often ask their doctors for a prescription. The drugs, seen as a miraculous way to achieveachieve wards a perfect body shape, feed hope that impossible beauty standards can be attained with a weekly injection.

Despite the surge in demand for these drugs, it’s important to recognize that they alone cannot address the societal challenges associated with obesity. 

According to the WHO website, “Stopping the rise in obesity demands multisectoral actions such as food manufacturing, marketing and pricing and others that seek to address the wider determinants of health (such as poverty reduction and urban planning).”

“While we are unaware of the analysis used in the [MSF] study, we have always recognized the need for continuous evaluation of innovation and affordability levers to support greater access of our products,” said Novo Nordisk in a statement. “We continue to support greater health equity to those in need of diabetes treatment and care.”

Image Credits: Chemist4u, Pew Research Center.