North Darfur capital of El-Fasher from above.

Mass atrocities, rape, famine, sexual and ethnically targeted violence have plagued Sudan’s civil war since it erupted two years ago. With peace nowhere in sight, a new report released by Médecins Sans Frontières (MSF) recounts in devastating detail: nothing has changed. 

Based on interviews with over 80 civilians, MSF data and direct observations from its medical teams, the report documents the violence and humanitarian catastrophe unfolding in El Fasher, the capital of North Darfur, where the Rapid Support Forces (RSF) have encircled hundreds of thousands of people while laying the city under siege.

Mass killings and starvation are underway, MSF found. Food, water, and humanitarian aid are blockaded. Food shops and markets, water towers and pumps, hospitals and healthcare facilities are under constant attack.

The Sudan Doctors Network reports 239 children have died from malnutrition in El Fasher since January as nearly half of Sudan’s remaining population facing acute food insecurity turn to boiling weeds and wild plants to survive.

Gunfire, airstrikes and artillery are already raining down on the city as the warring factions compete for control. But MSF warned further escalation is still possible: an all-out RSF assault on the capital.

“In light of the ethnically motivated mass atrocities committed on the Masalit in West Darfur back in June 2023, and of the massacres perpetrated in Zamzam camp in North Darfur, we fear such a scenario will be repeated in El Fasher,” said Mathilde Simon, MSF’s humanitarian affairs advisor. “This onslaught of violence must stop.”

‘Clean El Fasher’ 

An MSF nurse attends to a patient amid the violence in North Darfur, April 2025. / MSF

Ethnically targeted attacks by the RSF on non-Arab communities, particularly the Zaghawa, are “protracting the ethnic violence that has ravaged Darfur for over twenty years,” MSF said.

“RSF and their affiliates repeatedly shelled neighbourhoods and gathering places of civilians known to be from non-Arab communities, ground attacks were systematically carried out, involving the looting of belongings, killing of civilians and razing of houses and infrastructure,” the report found. “Sexual violence was widely perpetrated, and numerous abductions were reported.”

The RSF is a descendant of the Janjaweed militia that led the Darfur genocide, targeting non-Arabs across the region and killing an estimated 300,000 people from 2003 to 2005. 

Mohamed Hamdan Dagalo, the general known as Hemedti who heads the RSF, led Janjaweed paramilitaries that burned villages, killed civilians and raped ethnic Africans across his native Darfur during the genocide. These crimes led to the indictment of his then-commander and deposed Sudanese president, Omar al-Bashir, by the International Criminal Court for war crimes and genocide.

With the shadow of a repeat of history looming over the province, MSF reported several witnesses testified they overheard RSF soldiers airing plans to “clean El Fasher,” raising the spectre of a second genocide – or that it is already underway.

“Only God knows what will happen in El Fasher,” one man, 41, told doctors. “But if the RSF take El Fasher, they will carry out ethnic cleansing and genocide, like what happened in El Geneina.”

El Geneina, the capital of West Darfur, was systematically cleared of its Massalit population by RSF and allied militias through killing and forced displacement in 2023. The total number dead in the violence is unknown. A UN expert panel estimated between 10,000 and 15,000 people were killed, while Sudanese Red Crescent staff identified 2,000 bodies on the capital’s streets before they stopped counting.

As MSF urges the warring parties to spare civilians and grant access for humanitarian organisations to provide critical aid to people in need, RSF forces took control of the tri-border area with Libya and Egypt in June, gaining control over critical supply routes and threatening to open new fronts in the civil war. 

“As patients and communities tell their stories to our teams and asked us to speak out, while their suffering is hardly on the international agenda, we felt compelled to document these patterns of relentless violence that have been crushing countless lives in general indifference and inaction over the past year,” Simon said.

Despite a UN arms embargo, weapons continue flowing to both sides through neighbouring countries, several of which, including Libya, Chad and the Central African Republic, are major arms trafficking hubs, UN experts say

While Egypt and Saudi Arabia back government forces, the UAE, Libya and Russian-linked Wagner Group support the RSF. The UAE has invested over $6 billion in Sudan since 2018, viewing the resource-rich nation as key to expanding its regional influence.

Around 40,000 people have been killed and 13 million displaced since the civil war began in April 2023, according to the latest UN estimates.

Peace, at this juncture, is nowhere in sight.

Nowhere to hide

Over 400,000 people were forced to flee to El Fasher from the Zamzam refugee camp, the largest displacement encampment in Sudan just south of the city, after an RSF ground assault in April that killed more than 500 civilians.

Those who made it to the city “remained trapped, out of reach of humanitarian aid and exposed to attacks and further mass violence,” MSF said – and there is no way out.

“Survivors who managed to flee have undergone further violence along the road, with men being specifically targeted, women and girls being raped and civilian convoys attacked,” the report found. 

“The harrowing level of violence on the roads out of El Fasher and Zamzam means that many people are trapped or take life-threatening risks when fleeing. Men and boys are at high risk of killing and abduction, while women and girls are subjected to widespread sexual violence.”

The millions who successfully flee Sudan find crisis there too.The World Food Programme warned Wednesday that life-saving assistance may soon shut down in the Central African Republic, Chad, Egypt, Ethiopia, Libya, South Sudan and Uganda – all grappling with their own domestic food insecurity needs – as funding cuts and new arrivals overwhelm support systems.

“This is a full-blown regional crisis that’s playing out in countries that already have extreme levels of food insecurity and high levels of conflict,” said Shaun Hughes, WFP’s Emergency Coordinator for the Sudan Regional Crisis. “Refugees from Sudan are fleeing for their lives and yet are being met with more hunger, despair, and limited resources on the other side of the border.”

Rape as a weapon of war

Violence and attacks on healthcare forced MSF to shut down operations in El Fasher and Zamzam camp.

Sexual violence has been a central feature of the violence in Sudan throughout the war. While both the Sudanese Armed Forces and the RSF have been found to commit sexual war crimes, the overwhelming majority are attributed to the RSF and its allies.

The UN Independent fact-finding mission on Sudan and Amnesty International separately found the militia had engaged in widespread sexual and gender-based violence, rape, sexual slavery, and abduction, among other crimes against humanity. RSF forces are further accused of using mass rape as a weapon of war and to assist ethnic cleansing efforts, using rape as a tool to drive fear and force women to flee.

“I have a certificate for first aid nursing. [When they stopped us], the RSF asked me to give them my bag. When they saw the certificate inside, they told me, ‘You want to heal the Sudanese army, you want to cure the enemy!,'” one woman, 27, told MSF. “Then they burnt my certificate and they took me away to rape me.”

No comprehensive statistics on sexual violence in Sudan exist. The latest number on confirmed cases, compiled by the advocacy group Together Against Rape and Sexual Violence and published on 4 June, documented 377 cases of rape since the war began.

Data on rape and sexual assault in war zones are notoriously inexact. In Sudan, survivors face an array of barriers from social stigma, to lack of adequate medical support, and a dysfunctional judicial system with no means to protect or prosecute if they speak out. The Sudanese government’s Unit for Combating Violence Against Women previously warned verified rape cases may represent as little as 2% of the total.

Since the start of the war, the number of people at risk of gender-based violence has more than tripled to 12.1 million people – 25% of the country’s population. The number of gender-based violence survivors seeking services increased 288% in 2024, according to UN Women.

The most harrowing finding came from Unicef in May: 221 rape cases against children were recorded by since the beginning of 2024. The youngest reported survivors were four one-year-olds. Sixteen child rape survivors, including the infants, were under 5 years of age. 

“Children as young as one being raped by armed men should shock anyone to their core and compel immediate action,” said Unicef executive director Catherine Russell.

Unicef found an additional 77 instances of sexual assaults against children, mostly attempted rape cases. Two-thirds of recorded cases were girls, but 33% were boys, which the agency noted requires “specific attention as they may face stigma and unique challenges in reporting, seeking help, and accessing services.”

“Millions of children in Sudan are at risk of rape and other forms of sexual violence, which is being used as a tactic of war. This is an abhorrent violation of international law and could constitute a war crime. It must stop.”

Southern spiral

The violence consuming Sudan threatens to spill across its southern border, where South Sudan, the world’s youngest nation, stands on the brink of a new civil war of its own.

South Sudan won independence from Sudan in 2011, ending the longest civil war in the history of the African continent. Twenty-two years of violence, disease and famine killed 2 million people, the highest civilian death toll since World War II.

Independence was quickly followed by civil war. In 2013, a break-down of the power-sharing agreement negotiated two years earlier resulted in five years of war, killing 400,000 and displacing 4 million before a new power-sharing agreement brokered in 2018 brought fragile peace to the fledgling state.

That agreement collapsed once again in March when President Salva Kiir’s forces arrested his former deputy Riek Machar, mirroring Sudan’s trajectory when two rival generals, charged with overseeing the country’s transition to democracy, instead dragged the country and its 50 million people into all-out war.

Since March, violence against civilians in South Sudan has since reached its highest level since 2020, the UN reported Wednesday, with 1,607 attacks in the first quarter of this year. Those include 739 civilians killed, 679 injured, 149 abducted, and 40 subjected to conflict-related sexual violence between January and March.

The escalating violence is already pushing South Sudanese civilians towards famine. Over 22,000 people are likely already starving, while nearly 60% of the population faces life-threatening food insecurity as a result of the escalating violence, the IPC warned in June.

Armed groups move freely across the porous border drawn only in 2011, with overlapping ethnic militias and historic alliances threatening to erase the fragile line between two conflicts – trapping 61 million people, once again, in a renewed cycle of violence.

“Given this grim situation, we are left with no other conclusion, but to assess that South Sudan is teetering on the edge of a relapse into civil war,” Nicolas Haysom, the UN’s top official in South Sudan, warned when the peace deal collapsed. “It would devastate not only South Sudan but the entire region, which simply cannot afford another war.”

Image Credits: MSF, UN Sudan Envoy.

Nigerian veterinary para-professionals on an animal health training course supported by the UN Food and Agriculture Organization (FAO).

As the world observes World Zoonoses Day, it’s important to remember that human health is intimately tied to the health of animals, wild and domesticated. 

Five years after COVID-19, the world remains alert to health threats that can cross over from animals to people. 

Alongside growing concerns over high-profile spillovers like avian influenza, the silent threat of everyday zoonoses – from salmonella in poultry to leptospirosis in livestock – continues to affect hundreds of millions each year. These infections may not all make front-page news, but their impact on human health is significant and largely preventable. 

Furthermore, these zoonotic diseases are on the rise. Virus jumps from animals to humans are increasing around 5% annually, meaning these pathogens are forecasted to cause four times the number of spillover events in 2050 than in 2020.

Clear trend of rising zoonotic disease spillovers to humans – with fatal consequences.

Given the interconnectedness of human and animal health, the best way to prevent zoonotic disease in people is to stop it from spreading in animals. However, we are currently falling short in this task as the threat of zoonoses appears to be increasing. 

Despite the recent adoption of the world’s first pandemic agreement at the May World Health Assembly, which explicitly recognized the need for integrated approaches known as “One Health”, gaps remain in veterinary infrastructure worldwide. This leaves the door open to another devastating cross-species outbreak. 

To address this, the world must strengthen the veterinary sector, from improved use of animal vaccines and other medicines to increased training and services. Importantly, recruiting and empowering veterinarians on the frontline is a practical and cost-effective way to reduce these risks and protect public health. 

Overall, zoonotic disease incidence represents 60 % of infectious diseases in humans. Common zoonotic diseases, such as salmonella, can originate in unprotected animals. Thankfully, these types of risks can be controlled through veterinary tools, but only if they are available.

Meanwhile, just 13 zoonoses are responsible for 2.4 billion cases of human illness and 2.2 million deaths per year. For example, more than a million people globally are affected each year by leptospirosis, a dangerous and sometimes deadly disease caused by bacteria that transfers from animals to humans.

Emerging zoonotic disease events 1940-2012. The United States and Europe are also hotspots.

According to a new report from the World Organisation for Animal Health (WOAH), cases of avian flu in mammals doubled last year compared to 2023, for instance. In the EU, zoonotic diseases have been found to be on the rise

No animal health references in WHO pandemic agreement

Sampling dead animals in the Congo basin for zoonotic diseases that could spark an outbreak – or a pandemic.  The WHO pandemic agreement ignores animal health.

Despite opportunities to agree on and implement preventative measures, they have not been sufficient to address the risk at hand. The World Health Assembly recently adopted the first pandemic agreement, yet the agreement is missing any mention of veterinary medicine and animal health. Without this inclusion, the agreement can never fully fulfil its aim to prevent pandemics.

Disruptions from zoonotic disease outbreaks carry a significant cost to the global economy. The estimated direct cost of the loss of life due to zoonotic diseases is $212 billion annually, not including the costs associated with long-term treatment or ulterior damages. 

Conversely, the estimated cost of preventative measures, including monitoring and surveillance of risks as well as landscape management, is around $20 billion. In other words, preventing these diseases is more than ten times cheaper than dealing with the consequences.

Protecting food security and farmers’ livelihoods, especially in developing countries, is another reason to take a proactive approach to preventing zoonoses. When livestock contract a disease, farmers often must cull their flock or herd to prevent further spread of the illness. This impacts food availability and prices and creates massive losses for farmers.

While difficult to calculate, the estimated loss of animals due to disease varies from 20% globally to 50% in developing countries. Furthermore, the burden of zoonotic disease falls heavily on low- to middle-income countries, where health infrastructure is limited and communities rely heavily on livestock.

Countries must invest in veterinarians and proactive disease control

Kenya
A Kenyan herder, Kibet Ngetich Stephen, is visited by a community health volunteer who checks on the vaccination status of his herds, which can be exposed to anthrax and other deadly diseases due to their mingling with wild animals while out at pasture.

To build more resilience to zoonotic disease outbreaks, there are fundamental actions that must be undertaken. First, countries must invest in their veterinary workforces, training, and infrastructure. Investing in this field allows for well-resourced, trained, and capable veterinary services that can effectively address threats and protect animal health before an outbreak occurs.

In the UK, for instance, a new initiative offers farmers subsidised veterinary visits for multiple herds or flocks to help prevent disease.

Countries must also adopt proactive, rather than reactive, disease control strategies. Improving proactive strategies such as monitoring, detection, and vaccination can prevent or at least minimize the impacts of an outbreak. 

Furthermore, we must enhance public-private partnerships. Taking advantage of the speed at which the private sector can develop urgently needed technologies, such as vaccines, diagnostics and treatments, alongside the expertise of veterinarians and reach of public institutions, can ensure more effective measures against zoonoses.

With diseases like avian flu on the rise and everyday threats like salmonella continuing to impact public health, the world must adopt a coordinated approach to avoid zoonotic outbreaks. The losses caused by animal disease outbreaks are compounded by an order of magnitude when they spread to people. Improving animal health is the best way to protect the health of all.

Carel du Marchie Sarvaas is the executive director of HealthforAnimals, the global animal health association representing manufacturers of veterinary pharmaceuticals, vaccines and other animal health products.  He is a Dutch national and holds degrees from the University of Leiden and Johns Hopkins University.

John de Jong is the president of the World Veterinary Association, and a small animal practitioner in Boston, MA. He is also a former board member of the American Veterinary Medical Association serving as Chair (2015-2016) and as President (2018-2019).

Image Credits: FAO, BMJ, November 2023, ILRI/FLICKR, Sebastien Assoignons/ Wildlife Conservation Society, International Federation of Red Cross and Red Crescent Societies / The Kenya Red Cross Society.

The world faces a global health funding crisis, but John-Arne Røttingen believes the solution goes beyond money. It lies in stronger partnerships between governments, researchers, and citizens.

“Science is not enough to change the world,” said Røttingen, the newly appointed CEO of Wellcome, one of the world’s largest global health foundations. “It must be allied with collaboration and action across society.”

In a wide-ranging conversation on Trailblazers with Garry Aslanyan, Røttingen spoke about his leadership values, his vision for Wellcome, and the pressing need to rethink how global health is funded and delivered. A former head of CEPI and Norway’s global health ambassador, Røttingen said foundations like Wellcome must act as catalysts—not substitutes—for government and private-sector leadership.

“We need to engage governments more directly,” he said. “Ultimately, it is governments that are responsible for the health of their populations.”

Røttingen emphasized the importance of equity in science, calling for more research led by local experts in the Global South. He described visits to research centres in Malawi, Kenya, and Vietnam, where Wellcome supports programs that combine population health with advanced laboratory science.

But trust is also key.

“We need to double down on trust in science,” he said, citing public skepticism during the COVID-19 pandemic. That includes involving communities more directly in setting research priorities.

“We have to tackle problems that are important to people,” Røttingen added.

Røttingen urged the global health community to act fast as external funding shrinks and global crises multiply.

“We have some good indications of where we should go. We just need to act on them—and bring them to life,” he said.

 

Listen to previous episodes of the Global Health Matters podcast with Dr Gary Aslanyan on Health Policy Watch.

Image Credits: Global Health Matters Podcast.

Artificial intelligence can transform global health—but only if developed and deployed with equity in mind.

That was the message from two global health experts featured on the latest Global Health Matters podcast episode, “AI for Equity: Bridging Global Health Gaps.”

“In the future, a physician working in a remote area will have the best cardiologist in the world, the best pneumologist in the world, right next to them—ready to answer any questions,” said Alexandre Chiavegatto Filho, professor of machine learning in health at the University of São Paulo.

His team is developing mobile apps that allow frontline doctors to access AI tools through smartphones, even in areas without electronic medical records.

Jiho Cha, a South Korean parliamentarian and physician, has a similar vision. He believes AI can scale up health services in fragile settings, where doctors are scarce and health systems are overwhelmed.

“AI-powered information systems combined with fintech or blockchain technologies can improve health financing and delivery,” Cha said.

He described how AI can support nurses and community health workers by enhancing diagnostic and decision-making abilities.

However, both experts warned that the same technology could widen gaps if not handled carefully.

“If you leave AI by itself, it’s probably going to increase inequality,” Filho cautioned, noting that algorithms trained on wealthier populations tend to perform worse for low-income groups.

They said the challenge is to ensure AI is trained on diverse, locally relevant data and made accessible in low-resource settings. Otherwise, the digital divide will deepen.

“We have a huge opportunity in our hands,” Filho said. “But we need to make sure AI works where it’s needed most.”

Listen to previous episodes of the Global Health Matters podcast with Dr Gary Aslanyan on Health Policy Watch.

Image Credits: Global Health Matters Podcast.

 

In the most connected era in history, social isolation and loneliness present a growing public health crisis claiming hundreds of thousands of lives a year.

A three-year investigation by the World Health Organization found that loneliness and social isolation contribute to 871,000 deaths worldwide every year, a death toll researchers said places social health in a tier “as damaging as other public health risks” such as air pollution, tobacco and alcohol. 

The landmark report by the WHO Commission on Social Connection, published this week, found that one in six people globally are affected by social disconnection and loneliness, resulting in around 100 deaths per hour. 

“The sheer extent and scale of impact on our health – specifically loneliness – being linked to 870,000 deaths annually was really striking to me,” said Dr Vivek Murthy, co-chair of the commission and longtime champion of the harms of the social isolation “epidemic” in two terms as US Surgeon General.

“I think many people think of loneliness as just a bad feeling,” Murthy said. “But when you see numbers like that, it makes clear that it is massively consequential for our health and well-being.”

The commission found that loneliness and social isolation carry health risks similar to obesity and physical inactivity, increasing the risk of stroke by 32%, heart disease by 29%, and dementia by 50%. The conditions also contribute to diabetes, cognitive decline, and mental health problems including depression, anxiety, self-harm and suicide.

“The impact of loneliness is profound. It is often overlooked, despite being just as damaging as other known public health risks,” the commission wrote. “Make no mistake – connection is not just a nice idea. It is fundamental. Our ability to thrive, both as individuals and as nations, depends on our ability to connect with others.”

WHO Director-General Dr Tedros Adhanom Ghebreyesus noted that “social well-being” has been part of the WHO’s Constitution since the organization’s founding in 1948, “yet the social dimension of health is often overlooked,” a neglect that has persisted for over 75 years despite being fundamental to the WHO’s mission of health for all.

“In this age when the possibilities to connect are endless, more and more people are finding themselves isolated and lonely,” Tedros said. “Apart from the toll it takes on individuals, families and communities, left unaddressed, loneliness and social isolation will continue to cost society billions in terms of health care, education, and employment.”

As an increasing body of scientific evidence surveyed in the WHO report shows the extent of public health harms of social isolation and loneliness, which the Commission determined should be a “third pillar of health” alongside mental and physical health. But stigma stands in the way of main streaming awareness, funding and policy action.

Stigma around social disconnection and loneliness particularly affects people with disabilities, refugees, migrants, LGBTQ+ individuals, and indigenous and ethnic minority groups who may face additional barriers to social connection, the Commission said. 

“We may not always see it because of the shame and stigma, but it is there, taking a profound toll on our health,” Murthy said. In his role as Surgeon General, Murthy issued a warning in 2023 on the US “Epidemic of Loneliness and Isolation,” in which he compared the health risks to smoking 15 cigarettes a day.

“For too long, we have not recognized the importance of social health. We haven’t seen it for what it is – an essential pillar of our health and well-being,” Murthy said. “That must change.”

Who is hit hardest? 

Global prevalence of loneliness by sex and age group, 2014-2023.

The causes of social isolation and loneliness found in the report are in many ways features of modern life. They include digital technologies, low income and education, chronic health problems, living alone, lacking community and friendship networks. 

While loneliness affects all countries, demographics and income groups, the report found young people and those in low-income countries are the hardest hit. Contrary to common assumptions about loneliness primarily affecting older adults in the later stages of life, teenagers aged 13-17 reported the highest levels at 21%. 

For young people, the report’s findings reveal a paradox: despite living in the most connected era in history, technology has become a double-edged sword. The Commission warned of the negative health effects of excessive time spent on social media and screens for the mental health of young people – but they aren’t the first. 

During his second term as Surgeon General, Murthy issued a watershed advisory on the same subject, determining that there are “ample indicators that social media can also have a profound risk of harm to the mental health and well-being of children and adolescents.”

“At this time, we do not yet have enough evidence to determine if social media is sufficiently safe for children and adolescents,” the advisory said. The warning was necessary, Murthy said, because up to 95% of youth ages 13–17 report using a social media platform, with more than a third saying they use social media “almost constantly.”

“Even in a digitally connected world, many young people feel alone,” said Chido Mpemba, the African Union Youth Envoy who co-chaired the commission. “As technology reshapes our lives, we must ensure it strengthens—not weakens—human connection.”

Global prevalence of loneliness by WHO region, 2014-2023.

The findings also revealed significant regional disparities, with African countries reporting the highest levels of loneliness at 24% – more than double the European rate of 11% – surprising researchers. 

“We didn’t anticipate that rates of loneliness were going to be higher in low-income countries,” said one researcher involved in the study. The commission found that poverty may account for this trend, as limited economic opportunities can lead to social exclusion and encourage migration that breaks existing social networks.

While loneliness rates were similar between males and females overall, significant gaps emerged among specific age groups. Female adolescents showed the highest rates at 24.3%, while older men reported the lowest levels at just under 10%, challenging the dominant political discussion around male loneliness in the era of the manosphere. 

Global momentum builds 

Map of nations with national health policies addressing social isolation and loneliness.

The WHO report follows historic action by the World Health Assembly, which in May 2025 adopted its first-ever resolution specifically targeting social connection as a public health crisis. The landmark decision, co-sponsored by Spain and Chile, aimed to establish social connection as a standalone global health priority rather than a footnote in mental health policy.

“Today marks the first time social connection has been formally considered at the WHA,” Ailan Li, Assistant Director-General for Universal Health Coverage at WHO, told the Assembly following the vote. “This marks a crucial step in reframing how we understand mental and social wellbeing as central to health systems.”

The WHA resolution requests that WHO member states integrate strategies fostering meaningful social connections into national health policies through strengthened data collection systems, public awareness campaigns, and targeted support for vulnerable populations including people with disabilities, refugees, LGBTQ+ individuals, and single-parent households.

Currently, only eight WHO member states have adopted comprehensive national social connection policies: Denmark, Finland, Germany, Japan, Netherlands, Sweden, United Kingdom, and United States.

WHO Member States Recognize Social Connection as a Global Health Priority

Billions in economic costs

Jakob Forssmed, Minister for Social Affairs and Public Health in Sweden, told reporters the benefits his country’s policies have brought, arguing the public policy approach should recognize the economic costs – and benefits of action.

“When it comes to government [approaches], is critical to realize that this affects the economy, has a severe impact on economic life, because if you build trust between people, this will help the economy to grow,” Forssmed said. 

“If you don’t do these things, if you don’t do the work on social connection, you will find the economy go badly, and you will also have increased health costs. You will have more costs for elderly care. You will have more people, more kids in school, failing and things like that,” he added. “It is an investment, also in hard data. This is not just a soft issue. It’s an issue about societal growth, prosperity and well-functioning societies.”

The commission found that the economic costs of loneliness result from a waterfall effect. At a community level, loneliness undermines social cohesion and costs billions in lost productivity and healthcare spending, while teenagers experiencing loneliness were 22% more likely to achieve lower grades or qualifications, and adults struggling with social isolation face employment challenges and reduced lifetime earnings.

A growing body of research backs up the commission and Swedish minister and WHO commission’s view on the economics.

US employers alone lose $154 billion annually due to loneliness-related absenteeism, productivity losses, and turnover, or $1,685 per employee per year, while Medicare spends an extra $6.7 billion annually. In Spain, the estimated cost of loneliness through health-care expenditure and productivity loss in 2021 was 14 billion euros – 1.17% of Spain’s GDP that year.

“We now see that when children are struggling with loneliness and isolation, it negatively affects their educational outcomes,” Murthy explained. “When people are struggling with loneliness and isolation, it impacts how they perform in the workplace. It has a negative impact on engagement, which can have downstream effects on productivity, and a number of other outcomes that ultimately impact our economy.”

When he first became Surgeon General in 2014, Murthy has stated he “didn’t view loneliness as a public health concern.” Now, with the WHO commission report released, he and his colleagues hope to change that view worldwide.

“We now know that loneliness is a common feeling that many people experience. It’s like hunger or thirst. It’s a feeling the body sends us when something we need for survival is missing,” Murthy wrote in his 2023 Surgon General report.

“Given the profound consequences of loneliness and isolation, we have an opportunity, and an obligation, to make the same investments in addressing social connection that we have made in addressing tobacco use, obesity, and the addiction crisis.”

South Africans campaign in favour of a tax on sugary drinks in 2017.

Low-income countries could confront the massive health finance crisis they are facing after the withdrawal of most US-based aid through a 50% increase in the price of tobacco, alcohol and sugary drinks – saving 50 million lives and raising some $1 trillion dollars in vital revenue for strapped health systems, says WHO.

The ambitious WHO initiative “3×35 initiative” to increase by at least 50% the price of all three health-harmful products by 2035 was launched at the Fourth International Financing for Development Conference in Seville, Spain, which ends today.

“Health taxes are one of the most efficient tools we have,” said Dr Jeremy Farrar, WHO Assistant Director-General, Health Promotion and Disease Prevention and Control. “They cut the consumption of harmful products and create revenue governments can reinvest in health care, education, and social protection. It’s time to act.”

Noncommunicable Diseases (NCDs), including heart disease, cancer, and diabetes, account for over 75% of all deaths worldwide, with tobacco, sugary drinks and excessive alcohol consumption amongst the key causes.  A recent WHO assessment of experiences so far suggest that a one-time 50% price increase on all three products could prevent 50 million premature deaths by 2050 – as well as raising $1 trillion by 2035, WHO said.

The assessment is based on two decades of experiences with increased tobacco taxation, and more recently, country experiences with alcohol and sugary drinks taxes, WHO said.

Six out of ten smokers want to quit tobacco – WHO says taxes can help them do so.

Between 2012 and 2022, nearly 140 countries raised tobacco taxes, which resulted in increase of real prices by over 50% on average, showing that large-scale change is possible, said WHO, who launched the initiative along with the World Bank, the Organization for Economic Co-operation and Development (OECD) and about a dozen other civil society partners, including Bloomberg Philanthropies, the NCD Alliance, Vital Strategies and Movendi International, which works to reduce alcohol abuse.

While higher “sin” taxes have been a key component of WHO’s advocacy around NCDs for years, such calls have gained new urgency in the wake of the massive US cuts in global health funding – which have crippled vital health services related to HIV, nutrition, maternal and child health, and reproductive health in many African, Asian and Latin American countries.  See related story here:

USAID Formally Shut Down – Days After Scientists Warn Closure Will Kill 2.4 Million People Every Year

Meanwhile,  75 % of all lower-income countries are spending more on foreign debt payments than on health and education, as countries face even more pressure from forces like the International Monetary Fund (IMF) to make further austerity cuts.

Revenue raising successes in LMICs

Tobacco, alcohol and sugary drinks – evidence suggests it’s among the most effective tools for raising revenues and reducing health costs.

The 3×35 Initiative also marks the first time that the global health agency and its partners have rallied around a concrete target for dramatically raising alcohol, tobacco and sugary drink taxes. Not coincidentally, the initiative also coincides with the lead-up to the Fourth UN High Level Meeting on Noncommunicable Diseases, planned for September 2025, when countries will be asked to support a draft declaration that refers to such taxes as a key lever for reducing NCDs.

WHO’s claim that the tax initiative could raise $1 trillion for countries by 2035 is a projection. But by some measures, it is a conservative one, a WHO spokesperson said.  A 2024 Task Force on Fiscal Policy for Health, led by Michael Bloomberg, founder of Bloomberg Philanthropies, found that an excise tax increase sufficient to rise prices by 20% on all three products would mobilize some $2.2 trillion over five years, of which $1.3 trillion would be mobilised in low and middle income countries. Raising health taxes enough to generate a 50% price rise, moreover, would generate some $3.7 trillion, of which $2.1 trillion would be raised in LMICS.

Assessment by a Bloomberg-sponsored task force found even bigger potential revenues from the tax increases.

Along with the long experience in tobacco taxation, the projection is based on revenue-raising experiences with other health taxes in countries such as Colombia, Mexico, South Africa and Sri Lanka.

In Sri Lanka, the government exceeded its tax revenue target for the first quarter of 2024 in part thanks to two alcohol tax increases of 20% implemented in 2023, said Movendi. Another Movendi review of experiences in low- and middle-income countries including: Botswana, Estonia, Lithuania, Russia, South Africa, Thailand, and the Philippines, also found positive impacts on health, as well as economic benefits, of the tax increases.

As for the new 3×35 initiative, backing from Bloomberg Philanthropies, the World Bank and the Organization for Economic Co-operation and Development (OECD) also involves support for countries who want to take action.

Debunking industry claims

Mexican media campaign warning consumers of the health risks of sugary drinks.

Industry voices can be expected to push back hard against the initiative, with beverage industry voices, for instance, claiming that sugary drink taxes don’t reduce consumption.

“It’s deeply concerning that the World Health Organization (WHO) continues to disregard over a decade of clear evidence showing that taxing sugar-sweetened beverages has never improved health outcomes or reduced obesity in any country,” said Kate Loatman, executive director of the International Council of Beverages Associations, told Reuters.

However, a growing body of evidence in the United States, Latin America, and beyond and globally suggests otherwise.

When sugary drink taxes, for instance, were adopted, there were generally corresponding reductions in consumption, according to the Obesity Evidence Hub.

Two year’s after Mexico’s first sugary sweetened beverage (SSB) tax was first adopted, for instance, there had been a 37% reduction in total volumes of drinks purchased, one study found.  Reductions in purchases were greatest amongst poorer households and households that were formerly high consumers of SSBs. Based on those findings, the tax would prevent 239,900 cases of obesity over a decade, 39% in children, another 2019 study projected, with health-care cost savings four times greater than the costs of implementing the new regulation.

After South Africa introduced a 10% tax on sugary drinks, excluding fruit juices, there was a 57% drop in grams of sugar consumption from purchases of taxed drinks amongst people in lower socio-economic groups.  Manufacturers, meanwhile, reformulated their drinks with lower sugar levels to avoid the tax and respond to new consumer demands.

Image Credits: Kerry Cullinan, Sarah Johnson, Leo Zhuang/ Unsplash, Task Force on Fiscal Policies for Health 2024, Bloomberg Philanthropies, Bloomberg Philanthropies.

Air pollution is barely acknowledged in the draft political declaration for the upcoming fourth UN High-Level Meeting on Non-communicable Diseases (NCDs) and Mental Health. The omission of the world’s leading contributor to disease threatens global progress in tackling heart disease, respiratory diseases, stroke, cancer, and other chronic illnesses.

Since the last UN General Assembly High-Level Meeting on non-communicable diseases (NCDs) in 2018, air pollution has leapfrogged tobacco as a cause of disease and premature death worldwide.

Government representatives negotiating ahead of September’s meeting in New York City must commit to addressing this global health emergency of air pollution as the leading contributor to the global disease burden, causing more than one in ten deaths globally. 

Without clean air action, leaders will miss a golden opportunity to reduce the pressure on healthcare, improve the lives of billions of people living with NCDs, and prevent millions of cases of cardiovascular and respiratory disease, lung cancer, diabetes, mental health and neurological conditions including dementia.

In 2019, 99% of the world’s population was breathing air polluted beyond safe levels, according to WHO’s global air quality guidelines. The 2024 State of Global Air report by the Health Effects Institute shows that outdoor air pollution—driven largely by fossil fuels, transport, waste burning, and agriculture—causes 4.7 million deaths each year, while  household air pollution from cooking and heating with polluting fuels adds another 3.1 million deaths. 

That’s eight million preventable deaths every year—a staggering, unacceptable toll representing real people losing their lives to the very air they breathe.

The declaration of leaders meeting at UNGA must reflect the urgency of the issue, the life-saving potential of clean air, the cost-savings this offers to health services, and clearly call for integrated action on air pollution.

The unquestioned science

Almost everyone on earth breathes polluted air, with an impact far beyond the lungs. Fine particulate matter (PM2.5) enters the airways and is tiny enough to pass into the circulatory system and can reach nearly every organ, where it contributes to heart attacks, strokes, kidney disease, depression, anxiety, and impaired brain development in children. It also increases risks during pregnancy, including of miscarriage, stillbirth and low birth weight.

People living with NCDs are hit hardest. Air pollution causes more than a quarter of all deaths from ischaemic heart disease and stroke, almost half of all deaths from chronic obstructive pulmonary disease (COPD), and nearly a third of deaths from lung cancer, while worsening patients’ quality of life, prognosis and healthcare access. 

Countries are already off track to achieve SDG target 3.4—reducing premature NCD mortality by one-third by 2030. Most will find it impossible to meet this target without real action to reduce air pollution.

The good news is that proven, cost-effective solutions to allow us all breathe easier exist. Ministers of Health unanimously approved an updated WHO global roadmap on air pollution and health at last month’s World Health Assembly, including a target to halve mortality from anthropogenic air pollution by 2040. 

Progress towards the WHO Air Quality Guideline levels for healthy air is already underway in some regions. The European Union recently updated its Ambient Air Quality Directive, while China cut PM air pollution by more than half over the last decade, proving that clean air is compatible with rapid economic development. City mayors from every continent are showing leadership too, with 50 cities committing to stepping up clean air action earlier this year. 

Where the burden hits hardest 

Global map of national population-weighted annual average PM2.5 concentrations in 2020.

Like tobacco, alcohol and other major risk NCD factors, air pollution imposes an acutely unfair burden of disease on the lowest-income countries, and most marginalised communities. Ninety-five per cent of deaths linked to air pollution are of people in low- and middle-income countries, due to toxic pollution and under-resourced health systems. 

Despite the scale of this crisis, air pollution remains drastically underfunded. According to the State of Global Air Quality Funding 2024 report, clean air initiatives received less than 1% of international development funding between 2018 and 2022. This chronic neglect is not just a public health failure—it’s an economic catastrophe, with a toll counted in lost lives and livelihoods worldwide. 

The World Bank estimates that the cost of air pollution at US$6 trillion annually—equivalent to 5% of global GDP—from lost labour income due to illness and premature death, reduced productivity, and increased healthcare expenditures. In some of the hardest-hit countries, especially in South and South-East Asia and sub-Saharan Africa, air pollution costs exceed 10% of national GDP. 

These economic wounds stall development, entrench poverty, overwhelm fragile health systems and reveal a stark disconnect: the world is losing trillions to an entirely preventable crisis while making virtually no investment to stop it.

Fossil fuels: the overlooked driver 

An oil rig operates off the coast of Denmark.

NCD Alliance (NCDA) has voiced strong concerns over the draft political declaration, particularly the absence of any mention of fossil fuels—by far the leading driver of air pollution. Reducing fossil fuel extraction and use, phasing out subsidies, and ensuring just transition to clean energy must be central to NCD prevention efforts, but such commitments are currently absent.

NCD Alliance recommends clearly acknowledging the public health emergency posed by air pollution calls on governments to include an additional tracer target: “at least 80% of countries have adopted air quality standards to align with WHO air quality guideline level by 2030.” 

Air pollution was recognized as a major NCD risk factor by leaders at the last High-Level Meeting on NCDs in 2018, together with mental health and neurological conditions as one of the major NCD groups, creating a “5×5” framework for the NCD response. Since then, the evidence has only grown stronger on health impacts of air pollution, climate change and environmental degradation.

NCDA therefore calls for the stronger inclusion of air pollution, food systems and climate change in the text, and urges leaders to address this important nexus. Failure to do so would ignore emerging risks and lead to missed opportunities for more integrated, efficient, and forward-looking action.

Political momentum building

WHO’s Maria Neira, centre, receiving a health sector call for clean air action, presented by respiratory disease patients and paediatricians, at the WHO Air Pollution and Health Conference, March 2025.

At the 2nd WHO Global Conference on Air Pollution and Health in March 2025, governments and stakeholders endorsed a bold goal: halving the health impacts of air pollution by 2040. That target was formally approved by the 78th World Health Assembly. Achieving it would prevent three-to-four million premature deaths annually—most of them from NCDs. 

This aligns with the Sustainable Development Goals, including SDG 3.4 (reduce premature NCD mortality), SDG 3.9 (substantially reduce the number of deaths and illnesses from hazardous chemicals and air, water and soil pollution), SDG 7.1 (ensure universal access to affordable, reliable and modern energy services) and SDG 11.6 (improve air quality in cities).

Leading health organizations have joined the call to action, singling out air pollution as a deadly yet underfunded and solvable crisis. The Union for International Cancer Control (UICC) has identified air pollution as a missed opportunity to improve cancer survival, noting significant differences in prognosis in more polluted countries and cities.

The World Heart Federation (WHF) has also sounded the alarm on air pollution as an under-addressed driver of cardiovascular disease, with over half of the nearly eight million annual air pollution-related deaths are due to cardiovascular conditions, according to its 2024 World Heart Report. 

WHF urges governments to adopt the 2021 WHO air quality guidelines as legally binding standards and to align clean air targets with climate and urban planning policies. Their message is clear: protecting heart health means tackling pollution at its source—especially fossil fuels—and integrating environmental, health, and economic agendas.

A test of global leadership

The General Assembly hall in the United Nations’ New York City Headquarters.

Omitting air pollution from the NCD agenda is not just an oversight—it’s a dangerous misstep. The upcoming High-Level Meeting is a unique opportunity to correct course. World leaders must explicitly commit to act on air pollution as a major NCD risk factor in their political declaration. 

This should include developing national air quality standards that align with WHO guidelines, curbing emissions from key sources, and evaluating the cost savings from cleaner air to inform health system planning and budgets. Governments and donors must step up with stronger investments in clean air, especially for the most affected communities.

Clean air is not a luxury—it is a human right, especially for people living with NCDs. 

Leaders have the power to reverse this public health failure and economic disaster while delivering clear public health policy success: hospital admissions falling within days and weeks, healthier babies born in the ensuing months, and NCD trends continuing to improve over decades.

The science is beyond doubt, the solutions are proven, and Ministers of Health and Environment have committed on the international stage. The world now needs leaders to recognize the urgency of this crisis and seize this opportunity to save both lives and money. Including air pollution in the NCD agenda is not optional—it is vital.

About the authors

Alison Cox is the Policy, Advocacy and Accountability Director of the NCD Alliance, a global network of civil society organisations dedicated to transforming the fight against noncommunicable diseases.

Nina Renshaw is a career-long advocate for clean air, joining Clean Air Fund as Head of Health in 2022. She has twenty years of experience of international policy and advocacy in diverse fields, including health, environment, economy, transport and international development.

Image Credits: Giorgia Galletoni , CC, Patrick Gruban.

USAID closes days after leading medical journal warned of millions of deaths per year from a halt to operations.

US Secretary of State Marco Rubio announced the official end of USAID, eliminating the world’s largest humanitarian aid agency just days after a landmark study warned the closure would cause 2.4 million preventable deaths every year.

The study published 30 June in The Lancet found USAID-supported programs saved 92 million lives in low- and middle-income countries over the past two decades, including 30.4 million children under the age of five. Without this support, researchers project 14 million additional premature deaths by 2030 – as a result of the closure of the agency founded in 1961.

“Unless the abrupt funding cuts announced and implemented in the first half of 2025 are reversed, a staggering number of avoidable deaths could occur by 2030,” warned the 15 authors of the study, led by  researchers at Barcelona’s ISGlobal and five other Spanish institutes, the Institute of Collective Health in Brazil, the Centro de Investigação em Saúde de Manhiça, Mozambique, and the University of California, Los Angeles.

Rubio has ignored such warnings.

In a State Department memo titled “Make Foreign Aid Great Again” announcing the shutdown, Rubio laid into USAID, stating its “charity-based” model was against American interests and that it spawned “a globe-spanning NGO industrial complex at taxpayer expense.” He also attacked recipient countries and regions – notably Sub-Saharan Africa – for not repaying the US with UN votes despite billions in aid.

The move marks the final chapter in the rapid dismantling of the agency since January, upon which millions of the world’s most vulnerable people relied upon for vital health, nutrition and other development assistance. That saga began in January, when Elon Musk, the world’s richest man, famously tweeted he had skipped “some great parties” to put USAID “into the wood chipper,” telling the agency: “Time to die.”

The Trump administration had previously cancelled 83% of its aid operations earlier this year, throwing the international aid world into chaos. What remains of old US AID programmes will be “targeted and limited,” and be folded into the State Department, the memo said.

“USAID viewed its constituency as the United Nations, multinational NGOs, and the broader global community—not the U.S. taxpayers who funded its budget or the President they elected to represent their interests on the world stage,” Rubio wrote, adding that the agency “has little to show since the end of the Cold War.”

‘No one has died’

US Secretary of State Marco Rubio told Congress no one is dying from tens of billions in cuts to foreign aid.

Rubio’s State Department letter makes no mention of humanitarian concerns, instead reflecting the transactional view that has underpinned the Trump administration’s trade policy and America First foreign policy approach.

As for the estimates mortality projections tabled by scientists,  the architects of USAID’s dismantling tell a different story: no one is, has or will die.

“No one has died because of USAID [cuts,]” Rubio told Congress in late May, months after the majority of its operations were already terminated. “No children are dying on my watch.”

Musk echoed the same sentiment in March: “No one has died as a result of a brief pause to do a sanity check on foreign aid funding. No one.”

Fact Check

The stories at country level say something very different.

In Sudan, a mother described watching her toddler die from a treatable chest infection after the termination of antibiotic supplies to local clinics following the USAID cuts.  Others watched their babies starve while older children died begging for food, after soup kitchens were closed, according to one field report  by the Washington Post. And the absence of US-funded disease response teams has made it harder to contain deadly cholera outbreaks, doctors reported.

In East Africa countries like Zimbabwe, where USAID has long provided HIV medication, the sudden cuts left thousands without access to life-saving antiretroviral drugs, according to another report, by Health Policy Watch.  See related story.

Bribes and Rationing of AIDS Medicine in Zimbabwe as Trump’s Aid Cuts Bite

Thousands of organizations running health clinics, vaccination centres, food distribution sites, water purification drives, and other life-saving activities will be forced to curtail activities or shut down altogether, cutting off basic services.

In 2023 alone, USAID provided essential healthcare to 92 million women and children, as well as services to 20 million people infected with HIV. Many of those services now gone or in suspension until Congress decides if it will extend the lifespan of the President’s Emergency Program on AIDS Relief (PEPFAR), whose latest one-year authorization expired in March.

International aid organizations, including UN agencies and major charities, are struggling to cope with the loss of more than $60 billion in US funding. Facing steep staff cuts and slashed budgets, none are positioned to quickly replace USAID’s operations or maintain the same reach to vulnerable populations.

USAID’s Health Legacy

Elon Musk, who was named a “special government employee” by the Trump administration, secured the president’s backing to eliminate USAID, the country’s foreign aid agency, sending shockwaves through global humanitarian efforts.

That “sanity check” on foreign aid has since morphed into a total halt. This is particularly dramatic in the health sector, where the US has been the backbone of aid – totalling nearly a third of all health aid globally – for decades as the Lancet illuminates what will be lost.

The Lancet analysis found that higher levels of USAID funding—primarily directed toward low and middle-income countries, particularly in Africa—were associated with a 15% reduction in all-cause mortality and a 32% reduction in deaths of children under five.

The agency’s programs achieved remarkable reductions across multiple disease categories: a 65% reduction in HIV/AIDS deaths (saving 25.5 million lives), 51% reduction in malaria deaths (8 million lives), and 50% reduction in deaths from neglected tropical diseases (8.9 million lives).

Among the programs affected by the cuts is the President’s Emergency Plan for AIDS Relief (PEPFAR), which has saved an estimated 26 million lives through HIV treatment and prevention. Its collapse would have immediate, devastating consequences: in just three months, nearly 136,000 babies – about 1,500 each day – would be born with HIV as pregnant women lose access to transmission-prevention medication.

Significant decreases were also observed in mortality from tuberculosis, nutritional deficiencies, diarrheal diseases, lower respiratory infections, and maternal and perinatal conditions.

“Is [USAID] a good use of resources? We found that the average taxpayer has contributed about 18 cents per day to USAID,” James Macinko, a health policy researcher at UCLA and study co-author told NPR. “For that small amount, we’ve been able to translate that into saving up to 90 million deaths around the world.”

Charity is bad

Low-income countries on average depend on foreign aid for one-third of their national health spending. Eight of the world’s poorest countries—South Sudan, Somalia, Democratic Republic of Congo, Liberia, Afghanistan, Sudan, Uganda and Ethiopia—rely on USAID for over 20% of their total foreign assistance.

Facing their highest debt burdens in decades, many of the world’s poorest nations are unlikely to be able to compensate for the budget hole blown open by USAID’s withdrawal.

Former President Barack Obama called the decision to dismantle USAID a “colossal mistake,” saying the agency’s efforts to prevent disease, fight drought and build schools made it synonymous with America itself. “To many people around the world, USAID is the United States,” Obama said.

Citing two anecdotes – a Zambian man who told American diplomats teaching his countrymen to “learn to fish” instead of receiving US aid, and an Ethiopian woman praising two-way investment schemes – Rubio said the new model will provide “targeted and limited” aid, while favoring nations who demonstrate an “ability and willingness to help themselves” and welcome US investment.

“The charity-based model failed because the leadership of these developing nations developed an addiction,” Rubio said. “That ends today, and where there was once a rainbow of unidentifiable logos on life-saving aid, there will now be one recognizable symbol: the American flag.”

The United States flag has for decades been on the center of all aid packages distributed by the agency.

Image Credits: White House .

The World Health Organization flag flies above its headquarters in Geneva.

World Health Organization Director General Dr Tedros Adhanom Ghebreyesus announced his new team of 36 directors at headquarters on Tuesday, according to an internal message to WHO staff, seen by Health Policy Watch.

Nine of the appointments, including key positions heading the Departments of Noncommunicable Diseases and Mental Health, and the newly-combined Department of Environment, Urban Health, Climate, Migration, and One Health, are “acting” with permanent appointees to be named at some point in the future, according to the message. 

The appointment of the directors completes the latest phase of WHO’s reorganisation following budget crisis triggered by the withdrawal of the United States, WHO’s biggest donor, in January 2025, and its abrogation of dues payments, even for the 2024 year. 

In the wake of the US exit, WHO member states slashed WHO’s projected 2026-27 base budget by over 20%, yet it remains about $1.65 billion underfunded. In May, World Health Assembly members also agreed to a 20% increase in assessed fees for member states, handing a lifeline to WHO’s operations. Still, WHO is faced with a need to reduce overall staff costs by 20-25%

In May, Tedros slashed the number of major WHO programme divisions from 10 to just four, announcing a pared-down senior leadership team of six Assistant Director Generals, as compared to 11 previously.  Tedros also promised to reduce the number of costly D1 and D2 directors in WHO’s headquarters from over 76 to just 34, as the next step in the massive restructuring.

In fact 36 directors were named today, and the fate of other directors not named for positions at headquarters remains to be seen. As most directors hold long-term contracts, it’s likely the organisation will try to match them to positions elsewhere in regions, as contract termination costs would also represent a heavy expense.

The sweeping leadership cuts at WHO follow months of upheaval across UN agencies as organizations from UNHCR to OCHA that cut similar shares of staff to adapt to the first US withdrawal from their operations since the UN’s founding in 1945 – a loss of billions of critical dollars across Geneva.

New WHO organizational plan, announced on 22 April, reduces 10 divisions at headquarters to just four.

Health Promotion, Disease Prevention and Control

Top amongst the familiar names in the big new division of Health Promotion, Disease Prevention and Control, headed by Jeremy Farrar, are: Katherine O’Brien, as director of Immunization, Vaccines and Biologicals;  Luz Maria De Regil, as director of Nutrition and Food Safety previously the unit chief for Multisectoral Action in Food Systems; and Etienne Krug, longtime director of the Department of Health Promotion, Social Determinants and a politically powerful WHO actor with strong connections to donors.

Tereza Kasaeva, former head of WHO’s TB department, has been named director of the newly combined WHO Department of HIV, Tuberculosis, Hepatitis, and Sexually Transmitted Infections. 

Meg Doherty, who formerly headed the HIV Department, has meanwhile, been named as director of the department of Science, Research, Evidence and Quality for Health, under the new Chief Scientist, Dr Sylvie Briand. 

Tereza Kaseva in her previous role as TB department chief.

The twin appointments of Kasaeva, a Russian national,  to the new HIV/TB Department and Doherty, an American, to the department under the Chief Scientist’s office represent a kind of Solomonic choice for Tedros, observers said.  Despite the US abrogation of its engagement with WHO, Tedros has been careful about ruffling geopolitical feathers on either side of the Atlantic.   

Meanwhile, Pascale Allotey has been named director of two major departments that remain distinct in name, at least for now. Those include the new WHO Department of Maternal, Newborn, Adolescent and Child Health; Healthy Ageing, and Sexual and Reproductive Health, a merger of three former teams. Allotey is also slated to lead the Human Reproduction Programme, a WHO-hosted joint initiative with the UN Development Programme (UNDP), the UN Population Fund (UNFPA) and UNICEF, the UN Children’s Fund.

WHO Organization, as of January 2025, boasted 10 divisions and nearly 60 departments.

Health Systems

Dr Yukiko Nakatani (middle), heads Health Systems, one of three major programme divisions in the new WHO reorganization.

In terms of the second of three big new programme divisions, Health Systems, headed by Yukiko Nakatani, Rogerio Gaspar, a well-respected Portuguese researcher, has remained as director, Prequalification and Regulation of Medicines and Health Products – a critical WHO department that evaluates new medicines, vaccines, and medical devices. 

WHO’s “prequalification” seal of approval is regarded as a greenlight for bulk procurement by UNICEF, the Global Fund, and Gavi, The Vaccine Alliance, as well as for national ministries of health that lack capacity to do independent evaluations themselves.   

Similarly, Deusdedit Mubangizi is remaining as director, Policy and Standards for Medicines and Health Products, which works hand in hand to develop WHO’s Essential Medicines List decision. Notably a new EML on weight loss drugs and drugs for rare diseases is supposed to be forthcoming soon. 

In other key appointments to that division: Alain Bernard Labrique, a former professor at Johns Hopkins and WHO Director of Digital Health, is now the director of Data and Analytics, Digital Health, and Delivery for Impact; Dr Yvan Hutin is now director of  Antimicrobial Resistance; while Kalypso Chalkidou, who has led WHO’s Department of Health Financing and Economics since last year, was named as director of the newly-combined WHO Department of Governance, Financing, Economics, Primary Healthcare, Universal Health Coverage.  

Health Emergencies Preparedness and Response 

In the third new programme division of Health Emergencies Preparedness and Response, where Chikwe Ihekweazu has replaced the retiring Executive Director Mike Ryan is being replaced by, five department directors have been named.

Those named include: Altaf Sadrudin Musani, as director of Humanitarian and Disaster Management; Nedret Emiroglu, a long-time WHO European office figure as director of Pandemic and Epidemic Management; Stella Chungong, former director of Health Security Preparedness, now morphed into the Department of Health Emergency Preparedness. 

WHO ADG of Health Emergencies, Chikwe Ihekweazu (far right).

In terms of their public-facing profiles, they are largely unknown quantities, observers say. 

Other appointments include Oliver Morgan as director of WHO’s Health Emergency Intelligence and Surveillance, replacing Ihekweazu at the helm of the Berlin-based hub; and Abdirahman Sheikh Mahamud as head of the department of  Health Emergency Alert and Response Operations.

Notably, Maria Van Kerkhove, who was one of the most familiar faces of WHO during the COVID pandemic, and has remained the go-to expert on the virus in recent press briefings at WHO headquarters, was not named to a position in the Emergencies Division.

Director General’s Office 

In the Director General’s Office, Dr Jamal Abdirahman Ahmed is continuing as director of Polio Eradication following his appointment to the role in March.  

Derek Walton will remain in his role as chief legal counsel for the agency. Gaudenz Silberschmidt remains director, Partnerships, Resource Mobilization, Envoy for Multilateral Affairs. And Alia El-Yassir continues as director of Gender Equality, Human Rights, Health Equity, and Prevention of and Response to Sexual Exploitation and Abuse.

The WHO’s organizational restructuring accompanies a growing financial crisis at the agency, which faces a $1.65 billion budget shortfall for 2026-27 despite extensive fundraising efforts.

Unfilled and acting posts 

The nine key positions which remain officially vacant, and for which only acting directors have been named, include key strategic departments such as Noncommunicable Diseases and Mental Health (Devora Kestel) and the Department of Environment, Urban Health, Climate, Migration, and One Health, where Rüdiger Krech is taking over from WHO’s Maria Neira, the iconic face of WHO’s climate and environment work, who is retiring.  As per Tedros’ announcement, the old department of Health and Migration also appears to have also been grafted into that new mega-Department since the initial WHO organigram was published in May.

In the key post of WHO Director of Communications, Gaya Gamhewage, previously director of the Prevention & Response to Sexual Misconduct, will serve as acting director, taking over from Gabriella Stern, who is also retiring. 

Within the Division of Health Systems, the Director’s post for the Global Centre for Traditional Medicine will remain vacant, with Shyama Kuruvilla acting.

As for the new department of the WHO Academy, Health Workforce and Nursing – a merger of three former entities – the acting director is David Atchoarena, who was appointed in 2023 to head the WHO Academy, a flagship project of Tedros, following a long career at the UN Educational, Scientific and Cultural Organization, UNESCO. 

Dr. Gaya Gamhewage, Director, Prevention & Response to Sexual Exploitation, Abuse and Harassment, World Health Organization, speaks on 29 November, 2022 at the United Nations in Geneva.

The directorship of Malaria and Neglected Tropical Diseases also remains vacant, with Daniel Ngamije Madandi as acting.

In addition, the directorship of TDR, the Special Programme for Research and Training in Tropical Diseases, also remains vacant following the retirement just last month of John Reeder, an Australian national.  

With respect to TDR, another WHO-hosted programme, there has also been talk of appointing a director of a related WHO department as dual director for TDR – rather than making another distinct and costly appointment. 

Continuity or complicity? A leadership dilemma

Dr Mike Ryan, director of the World Health Organization’s emergency response division, held his final press conference Friday in Geneva after eight years leading the UN health agency’s response to global health crises.

While the new appointments mark an important step in WHO’s structural reform, they also underscore a deeper tension: how much continuity is too much?

Many of the individuals retained or reappointed to leadership positions are well-tested and respected professionals in their fields. Others, while familiar, are also emblematic of an entrenched culture that critics argue is ill-equipped for WHO’s current crisis.

But others arrived at WHO, not as a result of truly open global searches, but rather via internal handpicking — a trend that has accelerated under the current Director-General, eroding transparency and weakening trust in WHO’s merit-based system.

Some, like Dr Tereza Kasaeva, reportedly arrived with overt political backing (in her case, Russian authorities at the time of Dr Tedros’s first election), raising longstanding concerns about geopolitics shaping technical leadership.

Invisible retention and the illusion of reform

WHO Director-General Dr Tedros Adhanom Ghebreyesus and Raul Thomas, the Assistant Director-General for Business Operations at WHO address the committee following the successful vote on the agency’s new budget.

Despite the rhetoric of bold reform and downsizing, critics fear that many senior staff not formally reappointed may still be quietly retained within WHO’s financial system — undermining the promise of a leaner, more accountable leadership.

According to reports from staff with access to WHO’s Global Management System (GSM), the Canadian physician Bruce Aylward, formerly Assistant Director General for Universal Health Coverage and Life Course, so far remains listed on the WHO payroll records as a D2-level official until his retirement in 2027 –  even after being left out of the new six-member WHO senior leadership team, announced by Tedros in May.

Similarly, Santino Severoni, former director of Health and Migration, reportedly continues to be listed in WHO’s GSM records as a D1 director until 2029, despite the fact that he has not been named to any department so far.

These arrangements raise difficult questions about whether WHO is truly cutting fat or simply relocating it.

Meanwhile, others like Krech, who previously directed WHO’s Department of Health Promotion, was made the acting director of the newly merged Department of Environment, Urban Health, Climate, Migration, and One Health, despite a lack of intimate familiarity with that arena. 

“We hope there will be an open advertisement,” commented one source. 

Financial governance itself is now overseen in part by Sushil Rathi (acting director of finance), a figure whose own entry into WHO came via a process tied to the now-defunct Indian firm Satyam — the same company that originally built WHO’s Global Management System (GSM).

The hidden costs of keeping the old guard

WHO's New Leadership Team
World Health Organization headquarters in Geneva.

Financially, retaining internal appointees is the easier path. It avoids large indemnity payouts for terminated contracts and offers a surface-level appearance of continuity. But the cost of clinging to underperforming or politically tainted leaders may be far greater in the long run — eroding staff morale, weakening donor trust, and compromising the boldness needed for WHO to truly reinvent itself.

“We are caught in a trap. Either we recycle leaders who helped create this mess, or we bring in outsiders with no real grasp of WHO’s dysfunction,” said one senior staffer privately.

Without a robust, meritocratic and depoliticized process to identify the next generation of WHO leadership, the reforms risk being cosmetic — changing the structure while leaving the culture untouched.

Image Credits: US Mission in Geneva / Eric Bridiers via Flickr, WHO, WHO, 2025, Japan MoH, Edith Magak, Israel in Geneva/ Nathan Chicheportiche, Guilhem Vellut.

US Health Secretary Robert F. Kennedy Jr’s policy decisions run counter to the stated goals of his administration’s health agenda.

Since Robert F. Kennedy Jr suspended an independent presidential run to back Donald Trump’s bid for the White House, his laser-focus has been on one mission: “Make America Healthy Again” by attacking the threat of chronic disease.

Now sitting atop the United States health system, the anti-vaccine scion of the Kennedy dynasty released a major policy paper to advance that agenda last month, known as the “MAHA commission” report. Its centrepiece: the childhood chronic disease epidemic.

The 73-page document, pledging a return to “gold-standard” science and reversal of the childhood chronic disease crisis by “confronting its root causes—not just its symptoms,” was quickly found to be riddled with factual inaccuracies, mischaracterisation of research presented as evidence, and citations of at least seven studies that did not exist at all.

The report’s technical errors, bad science and blatant use of artificial intelligence dominated media coverage following its release.

Lost in the controversy over its scientific flaws was what the report left out: several of the deadliest causes of chronic disease in the United States – the very “epidemic” Kennedy’s MAHA manifesto claims to tackle.

Tobacco, the largest preventable cause of chronic disease in the US, causing lung cancer, heart disease and stroke, claims around 450,000 lives annually per CDC figures. It is never mentioned, despite most smokers starting as children.

Alcohol deaths, which rose 29% from 2016 to 2021, and drug overdoses claiming over 80,000 lives yearly – both risks that often begin in adolescence – are entirely absent, despite fentanyl being central to Trump’s ‘war on cartels’ and the deportation raids that sparked the largest protests in US history last week.

Air pollution, responsible for 50,000 to 200,000 preventable deaths in the US every year from chronic diseases such as heart disease, stroke, lung cancer and respiratory illness, is omitted entirely from the report.

“Pollution” writ-large – from vehicles, industrial emissions and other sources that cause chronic disease – is mentioned five times: four times in footnotes, with its sole appearance in the main text a reference to “light pollution” from smartphones, tablets and laptops disrupting sleep patterns.

Trump administration policies have banned the terms ‘pollution’ and ‘air pollution’ from federal documents, according to leaked memos and free speech groups.

Taken together, the report ignores the first, fifth, sixth and seventh leading causes of preventable death in the United States from chronic diseases – which the report, and Kennedy’s HHS, claim as their north star.

The chronic disease risk factors left out of the report are responsible for an estimated 2.2 million deaths annually – roughly 30% of all deaths in America and 70% from the top eight preventable causes each year as identified by the CDC.

“Those are big causes of death,” said Michael Brauer, an expert in chronic disease at the University of British Columbia and lead author on the global burden of disease report, a landmark international study compiling the causes of death around the world. “These are huge omissions.”

The MAHA commission’s four silos – children’s exposure to technology, ultra-processed foods, chemicals and overmedicalisation – fail to understand how chronic diseases work, Brauer added. Chronic diseases result from multiple risk factors – including but not limited to diet, sleep habits, smoking, environmental exposures, age and preexisting conditions – that pile up together, not single identifiable causes, he explained.

“It’s trying to pinpoint ‘this is the cause of this, this is the cause of that,” Brauer said. “For chronic diseases, that’s just not the way things work.”

Global food policy experts have also expressed doubts about Kennedy’s approach to ultra-processed foods – one of the four pillars he does address. They question whether he will follow necessary science and use proven interventions to tackle this threat.

A Secretary Undermining His Own Mission

Kennedy’s actions since taking office contradict his stated mission of making chronic disease his department’s top priority.

Despite insisting throughout confirmation hearings in Congress he would not stand in the way of access to vaccines, the HHS secretary – who rose to political prominence as the leader of the world’s largest anti-vaccine group during the pandemic – moved last month to remove the COVID-19 vaccine from the CDC immunisation schedule.

This would eliminate federal funding for COVID vaccines for uninsured children and pregnant women, effectively ending access for millions of Americans.

This comes as new estimates from the American Academy of Paediatrics find long COVID, a chronic neuroimmune disorder affecting the brain, spinal cord and nervous system with no known cure, may have overtaken asthma as the most prevalent chronic condition in US children.

Kennedy’s HHS argues children rarely die from COVID-19 – ignoring that long COVID has become a leading chronic condition among children, potentially placing millions at risk of an as-yet incurable disease.

Kennedy’s policy decisions also run counter to the emphasis placed on chemicals and environmental exposures for children in the MAHA report. While the policy paper dedicates one of its four chapters to this threat, he axed the division at the Center for Disease Control and Prevention (CDC) that investigates environmental hazards like heavy metals and air pollution – the very data required to craft policy protecting children from dangers highlighted by his own commission.

With the CDC’s environmental health division eliminated, protecting Americans from toxic exposures would fall even more heavily on the Environmental Protection Agency. Yet that agency faces a proposed 55% budget cut – from $9 billion to $4 billion – in the White House’s 2025 budget, the largest reduction in EPA history.

Administrative Assault

HHS is not alone in undermining the MAHA agenda – the Trump administration strikes new blows against the health objectives it claims to champion seemingly every week.

A wave of policies has targeted the agencies, programs, scientific research and laws that protect children and the wider public from chronic disease risk factors since the new administration took office – and members of the MAHA commission are leading the charge.

Commission members include Lee Zeldin, the EPA chief, and Russell Vought, the architect of Project 2025 and head of the Office of Management and Budget, who has spearheaded mass firings across the federal government’s scientific and health agencies.

Kennedy touts the firing of a quarter of the federal health workforce overseen by Vought — 10,000 total staff across the CDC, National Institutes of Health, and Food and Drug Administration — as necessary to rein in the “pandemonium” of “sprawling bureaucracy” and reverse the “chronic disease epidemic.”

Meanwhile, Zeldin’s EPA issued a legal filing on Tuesday “reconsidering” a ban on chrysotile asbestos, known as “white asbestos,” the last type of the deadly carcinogen still in use in the US. Asbestos exposure causes mesothelioma, lung cancer, and other fatal diseases that kill 40,000 Americans annually.

That filing included a statement of support from EPA administrator Lynn Ann Dekleva, who joined the agency from her post as a lobbyist for the American Chemistry Council – the petrochemical industry’s largest trade group representing Chevron, ExxonMobil, Shell, and other major corporations – which brought the lawsuit to reverse the ban the EPA now supports.

Labeling efforts to fight climate change a “cult” at a press conference in Washington last week, Zeldin announced his agency would remove greenhouse gas emissions limits from power plants.

The EPA stated in a press release that pollution from coal, gas and oil plants were “not significant contributors to dangerous air pollution,” deciding the agency should review pollutants individually before reconsidering emissions limits.

Asked if there is any uncertainty on the science of fossil fuel pollution’s health effects, Brauer was short: “No.”

“Anything burning is going to create air pollution and air pollution is harmful,” Brauer said. “That’s not something we need to reinvestigate or do more science on – it’s very clear.”

The same regulatory rollback removes limits on dangerous chemical discharges of mercury, arsenic and lead from power plants – chemicals that cause cancer, brain damage and developmental disabilities even at low exposure levels.

In an apparent contradiction, the EPA described the rule it is repealing – known as MATS – as “highly effective in protecting public health and the environment.”

The agency’s own press release cited the rule’s success: a 90% drop in mercury emissions from coal plants, 96% reduction in acid gas emissions, and 81% cuts in nickel, arsenic and lead discharges since 2012. The self-defeating argument suggests possible AI authorship of the release.

The EPA has already eliminated requirements for most power plants and heavy industry to monitor greenhouse gas emissions, citing financial burden to industry. It also pushed back a tax on methane emissions – the potent greenhouse gas up to 80 times more powerful than CO2 over 20 years – by a decade to 2035.

Beyond air emissions, the EPA postponed requirements for chemical manufacturers to disclose internal safety studies on 16 toxic substances – including known carcinogens like benzene and chemicals linked to developmental harm such as BPA – extending the deadline by more than a year to May 2026.

The delay keeps critical health data hidden from communities facing exposure to chemicals that cause cancer, brain damage in children, and reproductive disorders through everyday products like plastics, gasoline, and rubber tires – the very exposures the MAHA commission claims to prevent.

“We know industries will pollute to the levels they are allowed to,” Brauer said. “If we’re blind they’ll pollute more. That’s why we monitor – so we can enforce the laws that we have.”

Chemical Counter Currents

The MAHA report makes special mention of the threats of “Superfund sites,” described in the commission paper as “areas contaminated with industrial toxic waste which, depending on their level of contamination and cleanup status, could further compound their risk for chemical exposure and associated adverse outcomes.”

Nearly 25% of US children live in close proximity to one of the 1,341 Superfund sites nationwide, according to the report. These sites include abandoned chemical plants, former mining operations, ecological disasters, closed military bases with toxic waste, and industrial dumps where hazardous materials like lead, asbestos, and radioactive waste have contaminated soil and groundwater.

Yet the administration is systematically dismantling the agencies that protect communities from these very chemical hazards.

The Chemical Safety Board (CSB), an independent federal oversight committee that analyzes industrial chemical accidents and develops safety recommendations, is slated for elimination in Trump’s budget proposal. White House pressure led the CSB — a strictly advisory body with no power to legislate, fine or pursue legal action — to submit a budget request of zero dollars for the first time in its history.

The Clean Air Scientific Advisory Committee (CASAC) – an independent body of scientists created by Congress to ensure air quality policies protect public health from toxic pollutants including lead, mercury, and fine particulate matter – was similarly dismantled in January. Federal filings show the board remains empty at the time of writing.

Bodies like the CSB and CASAC serve as critical watchdogs for communities exposed to chemical risks and environmental pollution, investigating everything from refinery explosions and pipeline ruptures to toxic releases at Superfund sites, chemical plant fires, and industrial accidents that threaten nearby schools and neighborhoods.

Without these oversight bodies, residents near industrial facilities and contaminated sites lose their primary source of independent accident investigation, safety recommendations, and public health data. Communities would have no federal entity to determine why a chemical plant exploded, what toxins were released, or how to prevent future disasters.

The disconnect between the MAHA report’s concern for Superfund sites and the administration’s actions grows starker. The Trump administration has sued New York and Vermont to block laws requiring oil companies to pay for cleanup costs at the very Superfund sites the MAHA commission identifies as threats to children’s health.

The Department of Justice called these state efforts to hold polluters accountable “climate extremism” and “unconstitutional overreach,” despite the laws targeting the same contaminated sites Kennedy’s report warns endanger millions of American children.

“The last Administration wasted billions on ‘research’ and fake science in Green New Scam and culturally Marxist programs,” Rachel Cauley, a spokesperson for OMB, told E&E news of the administration’s rollbacks. “Under President Trump, our science agencies are actually doing science again.”

The Cost in Lives

As the administration dismisses climate science as “fake,” researchers at the University of Maryland published a first-of-its-kind analysis last week calculating the real-world costs of these rollbacks in lives and dollars.

Under what researchers describe as a “full rollback scenario” – reversing major legislation including the Inflation Reduction Act, infrastructure bills, and Clean Air Act protections totaling over $1 trillion, plus major EPA policy reversals – an estimated 22,800 Americans would die from increased air pollution over the next decade, with a $1.1 trillion loss to US GDP by 2035.

Fine particulate matter, known as PM2.5 – microscopic particles that penetrate deep into lungs and bloodstream, causing heart disease, stroke, and lung cancer – would increase by 10% under the rollbacks, killing approximately 3,100 additional Americans annually.

States with weaker air quality regulations would bear the heaviest burden in the absence of federal standards, with West Virginia, North Dakota, and Texas among the hardest hit, the report found.

The researchers note that 77% of IRA funding has flowed to Republican-majority districts – suggesting these lawmakers may face pressure from constituents benefiting from clean energy jobs and investments to preserve the programs, despite party opposition to the legislation.

“Basically this can be thought of as an underestimate,” said Alicia Zhao, the study’s lead author. “Like a lower bound of what repealing these clean energy policies could result in.”

The analysis excludes other toxic pollutants and climate impacts like intensifying wildfires – a growing threat as smoke laden with toxic particles increasingly blankets American cities, triggering asthma, heart attacks, early onset dementia, and premature death.

The administration’s proposed cuts would eliminate NASA and NOAA satellites that track this smoke, leaving communities without critical air quality warnings.

“Wildfire smoke is not something we’re going to be able to control,” Brauer said. “We can’t put a law and say: forests, stop burning! That’s exactly why we need to maintain progress on controllable pollution sources – not take our foot off the gas.”

Taking Aim at Air Pollution

These projected deaths would only increase under the administration’s legislative agenda. Buried within the 1,116 pages of Trump’s “Big Beautiful Bill” – the behemoth budget reconciliation measure currently before the Senate – lies a direct assault on America’s air pollution infrastructure.

An analysis by Health Policy Watch of the budget measure found nearly $37 billion in federal funding cuts to air quality and pollution programs running between 2021 and 2031 – the largest cut to air pollution funding in US history.

The eliminated programs, spread across the Inflation Reduction Act and Clean Air Act, include laws addressing air pollution at ports, schools, and cities; tailpipe emission restrictions for standard and diesel vehicles; air quality monitoring stations in low-income communities; reduction, reporting and enforcement of greenhouse gas limits nationwide; and EPA funding for timely scientific reviews.

While it remains unclear at the time of writing how much funding has been distributed from programs slated for termination, the Greenhouse Gas Reduction Fund – the largest single item at $27 billion – saw $20 billion frozen by the EPA in March.

If funds were distributed evenly over program lifespans, an estimated $5.88 billion would remain unspent through January 2025, or $25.88 billion including the frozen GGRF funds.

“This marks a stark turn from the waste and self-dealing of the Biden-Harris Administration intentionally tossing ‘gold bars off the Titanic,'” Zeldin said of freezing the GGRF funds, which he alleges were distributed through “crony capitalism” to partisan organizations.

Air pollution policies enacted by the EPA undergo rigorous cost-benefit analysis before approval. Despite their price tags, these regulations consistently deliver some of the highest returns on investment in government, ranging from 3-to-1 to 30-to-1 per dollar invested.

“We want to provide the public with the best information, full stop,” Brauer said. “We’re not doing this for any other reason. It’s to provide policymakers the information they need to prioritize how federal dollars are spent.”

“This is information that actually helps the government spend money more effectively,” Brauer concluded. “As a citizen, if the government is not doing that, then I don’t think the government’s doing its work well.”