Regulators are pivoting from monitoring toward establishing AI-principles in drug development.
Regulators are pivoting from monitoring toward establishing AI principles in drug development.

The European Medicines Agency (EMA) and the US Food and Drug Administration (FDA) have jointly established new AI principles in drug development to reduce regulatory divergence between the major markets of the European Union and the United States.

Industry associations have applauded the landmark accord, as it strengthens harmonisation across the regions – but emphasise that more concrete steps are needed.

With AI technologies becoming increasingly embedded in evidence generation or analysis in drug development, regulators are pivoting from monitoring to establishing principles-based guardrails to improve the accountability, integrity, and performance of the new technology.

The accord is likely to have a significant effect on global AI use in drug development, as the regulatory weight of the EMA and the FDA decisions sets global standards.

AI principles are ‘first step in renewed cooperation’

Olivér Várhelyi, European Commissioner for Health and Animal Welfare, hailed the new guidelines as an important step.
Olivér Várhelyi, European Commissioner for Health and Animal Welfare, hailed the EMA/FDA guidelines as a first step in a renewed EU-US cooperation.

The AI principles, published on Wednesday, (14 January), mark the culmination of a process that began two years ago to address the regulatory divergence between the major markets EU and the US. This was proving to be a significant barrier to digital innovation in pharma.

“The guiding principles of good AI practice in drug development are a first step of a renewed EU-US cooperation in the field of novel medical technologies,” said Olivér Várhelyi, European Commissioner for Health and Animal Welfare,

The goal is to preserve a “leading role in the global innovation race, while ensuring the highest level of patient safety,” he emphasised.

Industry associations welcome the accord

“We view the joint work of the EMA and FDA on developing these principles as a positive and important step toward global regulatory convergence,” the European Federation of Pharmaceutical Industries and Associations (EFPIA) told Health Policy Watch.

With memberships of 36 national associations and 40 pharmaceutical companies, EFPIA represents the business interests of the biopharmaceutical industry operating in Europe.

A press query with the Pharmaceutical Research and Manufacturers of America remained unanswered.

The ten guiding principles published in a joint decision by EMA and FDA.
EMA and FDA published AI principles in January to establish guardrails for drug development.

The AI principles aim to govern the use of the new technology across its entire lifecycle in drug development – from early-stage drug discovery and clinical trials to manufacturing and post-market safety monitoring.

This is to ensure that patient safety and ethical integrity remain paramount, emphasising a human-centric approach and oversight, as the US and EU regulatory bodies state.

With the new principles, the EMA and the FDA aim to dismantle the “AI black box”, as industry experts call it, with users and patients often failing to understand the process behind the generation of results.

According to the authorities, AI must be applied in well-defined contexts and be understandable: pharmaceutical or biotechnology companies are expected to use plain language to explain AI limitations and underlying data, while adhering to the protection of privacy and sensitive information.

AI principles to enhance accountability

The AI-principles address “shadow use” of AI in the industry.
The joint document addresses “shadow use” of AI in the industry.

Crucially, the joint document addresses a major issue in pharmaceutical operations known by industry experts as “shadow use”, namely that analysts are already working with large language models (LLMs) for daily tasks while leadership regularly looks the other way. This is to be countered by better oversight.

The provisions also aim to ensure clinical teams understand the technical tools being used by analysts by mandating that data scientists are integrated with clinical leads throughout the lifecycle of drug development.

Moreover, instead of single validation, continuous monitoring for “data drift” is required – a phenomenon where an AI’s performance degrades over time as the underlying data environment changes.

High-level declaration needs further steps

On 16 January 2026, EMA and FDA released Guiding principles of good AI practice in drug development.
On 16 January 2026, EMA and FDA released Guiding principles of good AI practice in drug development.

As the new AI principles are strategically designed to align with existing regulations, the guiding principles do not fundamentally change how AI is already being used by European industry, EFPIA explains.

However, they create the basis for a unified language in medical technology development, possibly with wide-ranging implications for global AI regulation in drug development.

“They help create a more coherent environment for scaling AI tools globally and for engaging with regulators in a consistent manner,” said the EFPIA.

While the guidelines mark a good foundation for the industry to lower the risk of duplicative or divergent requirements across regions, the AI principles remain high-level. Further steps toward concrete shared terminology, definitions, and concepts across regions are needed. Some of which are to be expected this year.

Image Credits: European Union/Christophe Licoppe, European Union/Frédéric Garrido-Ramirez, Felix Sassmannshausen, European Union/Barcelona Supercomputing Center , EMA.

The Africa CDC’s Professor Yap Boum told the media this week that the controversial trial has been cancelled.

A controversial clinical trial on the effects of the hepatitis B vaccine on babies in Guinea-Bissau has been “cancelled”, according to Dr Yap Boum of Africa Centres for Disease Control and Prevention (CDC).

However, this has been contested by the US Department of Health and Human Services (HHS), which is funding a Danish group to conduct the study, according to CIDRAP.

An HHS official told CIDRAP that researchers are still working on the study protocol, the official said, adding, “we are proceeding as planned.”

But Boum told a media briefing on Thursday that there were “ethical challenges” with the trial design, and Africa CDC had engaged with the health ministry of Guinea-Bissau about it.

“Our information is that the study has been cancelled,” said Boum, who added that while the continent needs research about vaccines, including hepatitis B, “this has to be done within the norms, so we are glad that at this point, the study has been cancelled”.

Boum, Africa CDC’s deputy incident manager for mpox who often stands in for the Africa CDC Director-General at media briefings, added that there would be “more engagement” with Guinea-Bissau.

The US Centers for Disease Control and Prevention (CDC) awarded Bandim Health Project at the University of Southern Denmark a $1,6 million five-year grant to study the “optimal timing and delivery of monovalent hepatitis B vaccinations on newborns in Guinea-Bissau”, according to the US HHS federal register.

The trial aimed to enrol 14,000 newborns in a “randomized controlled trial to assess the effects of neonatal Hepatitis B vaccination on early-life mortality, morbidity, and long-term developmental outcomes”, according to HHS register.

Half the babies would be vaccinated at birth, while the other half would get vaccinated six weeks later – which has raised ethical questions from researchers across the globe.

However, the World Health Organisation (WHO) has recommended universal birth hepatitis B vaccinations since 2009. Hepatitis B vaccination usually involves a series of three or four injections, and clinical trials have already established the best intervals for the vaccinations.

‘Non-specific effects’ of vaccines

One of the leaders of the Bandim Health Project at the University of Southern Denmark, Dr Christine Stabell Benn, is an adviser to the US Advisory Committee on Immunization Practices (ACIP), which recently resolved to stop recommending hepatitis B vaccines to US newborns. 

Stabell Benn’s research has focused on the “non-specific effects” (NSE) of vaccines. They have conducted trials involving thousands of children in Guinea-Bissau and Denmark, and assert that all vaccines should also be tested for NSEs.

The journal Vaccine recently published a scathing comprehensive review of 13 trials conducted by Bandim, which showed that their trials have been unable to show non-specific effects for measles, tuberculosis, diphtheria, tetanus, and whooping cough vaccines.

“We were surprised to find several instances of questionable research practices, such as unpublished primary outcomes, outcome switching, reinterpretation of trials based on statistically fragile subgroup analyses, and frequent promotion of cherry-picked secondary findings as causal, even when primary outcomes yielded null results,” according to the review, which was headed by Dr Henrik Støvring of the Department of Biomedicine, at Aarhus University in Denmark.

Study ‘manipulation’

Meanwhile, several high-profile health experts condemned the trial.

“[Robert F Kennedy Jr], the Secretary of Health and Human Services, will soon conduct his own Tuskegee experiment,” US paediatrician Dr Paul Offit, co-inventor of a rotavirus vaccine, wrote on his Substack platform.

“He has chosen the resource-poor nation of Guinea-Bissau, West Africa, to do it. Guinea-Bissau is currently overwhelmed by hepatitis B virus. About 18% of the population is infected,” added Offit, director of the Vaccine Education Center and an attending physician at Children’s Hospital of Philadelphia and a professor of both Paediatrics and Vaccinology at the University of Pennsylvania.

“RFK Jr. has manipulated the study to support his unsupportable, science-resistant beliefs about harms caused by the hepatitis B vaccine,” added Offit, who noted that as the study is single-blinded, researchers will know which children received a birth dose of the vaccine.

“This allows for investigator bias, where the investigator might find vague neurodevelopmental problems in the birth-dose group but not the six-week group,” he added.

Professor Gavin Yamey, director of the Center for Policy Impact in Global Health at Duke University, argues that “it is unethical to do a randomized controlled trial in which you withhold a proven, life-saving vaccine from newborn babies”.

Currently, babies in Guinea-Bissau only receive the hepatitis B vaccination from six weeks’ old. But some 11% of children in the country are already infected with hepatitis B by the age of 18 months, so the government has resolved to introduce vaccination at birth from 2027, as recommended by the WHO.

Bandim says its trial will stop enrolling participants when the government rollout of the hepatitis B vaccine to newborns starts. They will follow their cohort for five years, primarily to compare “overall mortality and hospitalisations,” and “secondary outcomes”, looking at “atopic dermatitis and neurodevelopment”, according to a Bandim media release.

Life-saving vaccines, maternal and child health, and programs fighting TB, malaria, and HIV/AIDS are included in the proposed bill.

The $9.4 billion package agreed to by the US Senate and House Appropriations Committees, is more than double the $3.7 billion requested by the Trump Administration, and signals bipartisan support for maintaining significant global health aid – although the package still must be approved by both Senate and House, and could also be vetoed by president following passage. 

The $9.4 billion package agreed to by Congressional leaders in the US House and Senate is less than the $12.4 billion allocation in 2024 and 2025. But it’s still $5.7 billion more than called for last September by US President Donald Trump in his America First Global Health Strategy

The House and Senate have yet to vote on the spending bill, and face a 30 January deadline to pass the federal funding. The legislation would then have to clear the President’s desk before becoming law.

The global health allocations are part of a larger $50 billion foreign aid spending package for the 2026 fiscal year. That foreign aid bill, while a 16% cut from 2024, is nearly $20 billion more than what the Trump Administration initially requested.

The broader bill also includes $5.4 billion in funding for humanitarian assistance. Some of the funds from that pot will also be dedicated to health – in areas such as food security and nutrition, shelter protection, and  water, sanitation and hygiene (WASH). And it also includes a nod to the Trump administration’s plan to offer low- and middle-income countries some $11 billion in direct bilateral assistance  – some of which will also be channeled into health. The bilateral deals replace some of the assistance provided previously under USAID, which boasted a budget of around $44 billion in 2023, shortly before Trump abruptly dismantled it last year, making the US the world’s largest overseas donor. 

Funding for HIV/AIDS, malaria, family planning

US global health funds 2026
Of the $9.4 billion, some $5.88 billion is dedicated to fighting HIV/AIDS – with about $4.5 billion allocated to PEPFAR (not named here), and the rest to Global Fund, UNAIDS, and related activities.

Of the $9.4 billion earmarked in the bill specifically for global health programs, some $5.9 billion would be allocated to HIV/AIDS – with $1.25 billion channelled through the Global Fund to Fight TB, AIDS and Malaria, $45 million to UNAIDS, and $4.5 billion through the President’s Emergency Plan for AIDS Relief (PEPFAR), the flagship US program founded in 2003. 

While that is still less than the $7.1 billion level of support to the three agencies under the 2024 Biden administration, it’s a major increase from the $2.9 billion for HIV/AIDS requested by Trump. At the same time, the bill also calls for PEPFAR, founded by former US President George Bush, to transition to a largely self-reliant program of national governments over the coming years. 

In terms of other global health priorities: $795 million is dedicated to malaria, and $379 million for tuberculosis; $85 million is earmarked for polio.

Strikingly, some $524 million for family planning and reproductive health services are also included in the funding package – despite the historic reticence of conservatives to fund such programs. 

And although the administration has ordered a US withdrawal from the UN Population Fund (UNFPA), Congress allocated $32.5 million for the organization, as part of the family planning funds. The bill does stipulate that the agency cannot spend these monies on China – and that if the Trump administration makes good on its plan to withdraw from UNFPA, the money should then be transferred to other global health programs. 

Allocations are earmarked for “Global Health Security,” $615.6 million for organizations like Pandemic Fund and the Coalition for Epidemic Preparedness Innovations (CEPI). These funds could also be used in the event of a public health emergency.

Funds will also go to neglected tropical diseases (NTDs) and nutrition.

New ‘National Security Fund’ also includes health components

In another twist, support for family planning, reproductive health and countering child marriage is also supported through a new “National Security Fund” of $6.77 billion that Congress aims to create – to “combat China’s influence” among other things.

The fund, which also includes monies for clean cook stoves, a Young African Leaders Initiative, peace process monitoring, trade capacity building, and assorted other priorities, specifies that at least 15% of the fund should go to the African continent. 

Bipartisan support, but with different takes 

Remarkably, both sides of the aisle – and congressional chambers – came together for the bill in a show of bipartisanship, and an exertion of Congress’s power of the purse. 

House and Senate Republicans are positioning the agreement as a win for reducing overall foreign aid spending – in this case by about 16% – while also countering growing Chinese influence and advancing President Trump’s foreign policy vision.

The bill is an “unprecedented reduction of spending” while still aligning with the “America First agenda,” said House Appropriations Chair, Representative Tom Cole (R-OK). 

Cole lauded the foreign aid bill’s larger design, saying it “eliminates wasteful spending on DEI or woke programming, climate change mandates, and divisive gender ideologies at the State Department,” and “holds the United Nations accountable.” The Republican Chair also noted that the bill “confronts human trafficking; provides support, funds, or assistance for Israel, Egypt, Jordan, and Taiwan; and denies China access to U.S.-backed resources.”

But for those across the aisle, the very act of funding global health programs resists the Trump administration’s fiery aid trajectory. 

The “[b]ill rejects Trump’s decimation of the U.S. foreign assistance enterprise— renewing bipartisan investments in American leadership and reasserting congressional control; Supports key global health, humanitarian, and development investments and rejects extreme House Republican riders,” reads a summary by Senator Patty Murray (D-WA), Vice-Chair of the Senate Appropriation Committee.

“While including some programmatic funding cuts, the bill rejects the Trump administration’s evisceration of U.S. foreign assistance programs and reaffirms bipartisan support for the full range of international initiatives long promoted by Congress to advance U.S. interests.”

WHO is not funded at all

Notably absent in the bill is any mention of funding for the World Health Organization, from which the Trump administration is in the process of withdrawing. Nor, is there provision in the bill for paying the $260.6 million in unpaid dues to the organization – for which the US is in arrears – before the pullout date later this month. See related story here. 

Member States to Discuss US Withdrawal from WHO as Failure to Pay Fees Violates Agreement

 

This story was updated 16 January to include stipulations on UNPFA funding.

Image Credits: WHO, Senate Appropriations.

2025 was among the top three warmest years on record, according to the World Meteorological Organization (WMO).

The year 2025 was among the top three warmest years on record, according to the latest update from the World Meteorological Organization (WMO).

Depending on the data set being used, the year was either the second or third warmest year on record.

The UN agency for monitoring the atmosphere also confirmed that the past 11 years have been the 11 warmest on record, and ocean heating continues unabated.

The global average surface temperature in 2025 was 1.44°C (with a margin of uncertainty of ± 0.13°C) above the 1850-1900 average that is used as a pre-industrial era baseline, WMO reported.

“The year 2025 started and ended with a cooling La Niña and yet it was still one of the warmest years on record globally because of the accumulation of heat-trapping greenhouse gases in our atmosphere. High land and ocean temperatures helped fuel extreme weather – heatwaves, heavy rainfall and intense tropical cyclones, underlining the vital need for early warning systems,” said WMO Secretary-General Celeste Saulo.

This update from the WMO comes less than two months after global leaders met in Brazil’s Belém for the annual UN climate conference, COP30. It confirms that the climate action so far is proving to be woefully inadequate as the streak of extraordinary global temperatures continues unabated.

A robust data set

Annual global mean temperature anomalies relative to the 1850-1900 average shown from 1850 to 2025 for eight datasets as shown in the legend.

What makes this data robust is that it is a consolidated analysis of eight different global datasets. Two of these datasets ranked 2025 as the second warmest year in the 176-year record, and the other six ranked it as the third warmest year.

The past three years, 2023-2025, are the three warmest years in all eight datasets. The consolidated three-year average 2023-2025 temperature is 1.48 °C (with a margin of uncertainty of ± 0.13 °C) above the pre-industrial era. The past 11 years, 2015-2025, are the 11 warmest years in all eight datasets.

“WMO’s state of the climate monitoring, based on collaborative and scientifically rigorous global data collection, is more important than ever before because we need to ensure that Earth information is authoritative, accessible and actionable for all,” said Saulo.

The update was timed to coincide with the release of global temperature announcements from the respective dataset providers.

One of the eight datasets is one from the National Oceanic and Atmospheric Administration (NOAA), the US agency that has had its funding cut by the Trump administration. Other data sets are from the European Union, Japan, China and the UK.

Six of the eight datasets are based on measurements made at the weather stations, and by ships and buoys using statistical methods to fill gaps in the data. Two of the datasets combine past observations, including satellite data, with models to generate a consistent time series of multiple climate variables, including temperature.

The actual global temperature in 2025 was estimated to be 15.08°C, but there is a much larger margin of uncertainty on the actual temperature at around 0.5°C than on the temperature anomaly for 2025, WMO said.

Oceans continue to heat

Ocean heat content continued to rise in 2025.

Roughly 90% of excess heat in the atmosphere is absorbed by the world’s oceans, warming them in the process. This makes ocean heat a critical indicator of climate change.

separate study published in Advances in Atmospheric Sciences reports that ocean temperatures were also among the highest on record in 2025, reflecting the long-term accumulation of heat within the climate system. And while warming temperatures affect life on Earth, the warming oceans pose a threat to the coral reefs and life in the water.

From 2024-2025, the global upper 2000m ocean heat content (OHC) increased by ∼23 ± 8 Zettajoules relative to 2024, according to the study led by Lijing Cheng with the Institute of Atmospheric Physics at the Chinese Academy of Sciences. That is around 200 times the world’s total electricity generation in 2024.

Regionally, about 33% of the global ocean area ranked among its historical (1958–2025) top three warmest conditions. Another 57% fell within the top five, including the tropical and South Atlantic Ocean, Mediterranean Sea, North Indian Ocean, and Southern Oceans, underscoring the broad ocean warming across basins.

While the global annual mean sea surface temperature (SST) in 2025 was 0.12 ± 0.03°C lower than in 2024, it was 0.49°C above the 1981–2010 baseline, showing long-term warming trends.

State of the Global Climate 2025 report

A climate change protest

While the current update was meant to give an indication of the global temperature trend, WMO’s State of the Global Climate 2025 report to be issued in March will go further.

WMO will provide a detailed breakdown of key climate change indicators, including greenhouse gases, surface temperatures, ocean heat, sea level rise, glacier retreat and sea ice extent.

The datasets being relied by the WMO provide a near-complete global picture of near-surface measurements using statistical methods to fill gaps in data-sparse areas such as the polar regions.

Image Credits: WMO, WMO, WMO, Markus Spiske/ Unsplash.

Vaccine hesitancy gave way to more acceptance once jabs and public information on safety was available.
A health worker getting vaccinated against COVID-19 in Bulgaria in 2021.

Fears over the side effects of COVID-19 jabs, which led to initial vaccine hesitancy, mostly gave way to acceptance in the course of the pandemic, with only a small minority remaining unvaccinated due to deep-seated mistrust, a new major study published in The Lancet finds.

For the first time, the study “Profiling vaccine attitudes and subsequent uptake in 1.1 million people in England” compared attitudes towards vaccinations with actual vaccination behaviour on a large scale. Based on the findings, health policy experts call for evidence-based, group-specific and long-term communicative approaches to counter vaccine hesitancy.

Many of the initially hesitant individuals chose a wait-and-see approach. They were driven by concerns over side effects and efficacy, but eventually opted for the jab as real-world evidence of safety and efficacy grew.

The benefit of vaccination was recognised by the majority of those initially hesitant, mainly due to public health communication, community outreach and vaccine rollout itself.

“Our findings suggest that most COVID-19 vaccine hesitancy was rooted in concrete concerns that can be addressed and successfully overcome with time and increasing availability of information,” according to the principal authors, Paul Elliott, who is Chair in Epidemiology and Public Health Medicine at the Imperial College in London, and Marc Chadeau-Hyam, Professor of Computational Epidemiology and Biostatistics.

Vaccine hesitancy plummeted once information was available

Vaccine hesitancy plummeted with rollout and information available
Vaccine hesitancy plummeted with the vaccine rollout and information.

According to the data, vaccine hesitancy decreased for the vast majority of initially hesitant individuals in the course of the COVID-19 pandemic.

Over time, 3.3% of all participants were categorised as hesitant towards the COVID-19 vaccine. Individuals were classified as “vaccine-hesitant” if they stated they would refuse the vaccine, had already refused it, or had not yet decided.

Their number fluctuated, plummeting from 8% in January 2021 to 1.1% at the start of 2022, before rising again to 2.2% in February 2022. This slight rise might be the result of “pandemic fatigue” or a shift in “personal risk perception” in the course of the Omicron wave.

The study data is based on the Real-time Assessment of Community Transmission (REACT) studies, which monitored the prevalence of SARS-CoV-2 in England during the COVID-19 pandemic from 1 May 1, 2020, to 31 March, 2022, in random samples of the population.

The researchers linked consecutive survey data from 1.1 million adults in England to official National Health Service (NHS) health records. The participant questionnaires included queries about vaccination status and attitudes toward vaccines, significantly enabling a comparison. However, the results may under-represent the most radical critics, who often avoid scientific surveys.

Concrete health concerns caused vaccine hesitancy

Vaccine hesitancy was mainly driven by concerns over side effects and efficacy.
Vaccine hesitancy was mainly driven by concerns over health concerns, side effects and efficacy.

Vaccine hesitancy was mainly grounded in concrete concerns about effectiveness and side effects, perception of low risk from COVID-19, mistrust of vaccine developers, and fear of vaccines – sometimes as a result of misinformation, the researchers found.

The most prevalent categories of hesitancy, related to effectiveness and health concerns, declined substantially over time as  65% of hesitant participants received one or more vaccinations by May 2024.

The reasons for initial vaccine hesitancy varied by demographic. Men were more likely to perceive themselves as not being at risk (17.9% versus 10.2% of women), while women more frequently cited concerns regarding fertility (21.2% versus 8.4% of men). Younger participants more frequently cited a fear of needles.

Socio-economic deprivation and institutional mistrust are primary drivers of the reluctance to get a jab. Notably, Black participants were three times more likely to express hesitation than White participants.

Experts interpreting the study also suggest this mistrust is frequently rooted in negative healthcare experiences or historically unequal treatment. Significantly, non-White participants were ultimately no less likely to be vaccinated at a later date.

Communicative approaches key to successful campaigns

Vaccine hesitancy is best countered by transparent, long-term, and evidence-based information provision, public health expert Sarah Eitze emphasises.
Vaccine hesitancy is best countered by transparent, long-term, and evidence-based information provision, according to public health expert Sarah Eitze, researcher at the Institute for Planetary Health Behaviour (IPB) at the University of Erfurt in Germany.

Although the researchers did not test the success of specific communication efforts or interventions to shift attitudes toward vaccinations, the findings can be used in public health policy and future vaccination campaigns, according to Sarah Eitze, deputy director of the WHO Collaborating Centre for Behavioural Research in Global Health.

Transparent, continuous, and evidence-based information provision has proven to be effective, explained Eitze, who is a researcher at the Institute for Planetary Health Behaviour (IPB) at the University of Erfurt (Germany).

“Optimal communication about vaccination is most successful when we take a more evidence-based, target group-specific and long-term approach,” said Eitze.

“The study shows that not every form of vaccine scepticism works in the same way. While uncertainty about information can often be addressed effectively, deeply rooted attitudes of rejection based on mistrust of institutions or science are much more difficult to overcome.”

Image Credits: European Union/Martin Matev, Felix Sassmannshausen, European Union/Martin Matev, Lisa Wollenschläger/University of Erfurt.

Steven Solomon, WHO’s legal officer.

When and how the United States withdraws from the World Health Organization (WHO) is an “open question” for member states to discuss, according to Steven Solomon, the body’s legal officer.

This is because the US has failed to pay its WHO membership dues of $260.6 million for the past two years (2024-2025) in violation of a 1948 agreement with the body.

According to the terms of this agreement, the US needs to give the WHO a year’s notice and pay its membership fees in full for that year before withdrawing.

Next Tuesday – 20 January – will be the first anniversary of US President Donald Trump’s announcement that the US would be leaving the WHO. 

But while the one-year notice period is up, member states need to discuss how to deal with the US failure to pay its membership fees. This discussion will take place at next month’s executive meeting and at the World Health Assembly in May, Solomon told a media briefing on Tuesday.

The US is the only country to have negotiated exit terms from the WHO, as the WHO Constitution makes no provision for member states to withdraw, he added.

“In 1946, the drafters [of the treaty that established the WHO] understood the historic struggles against the international spread of disease, and they saw how a truly universal organisation would make the world safer, so they did not include a withdrawals clause,” said Solomon.

“Instead, they provided flexibilities within the treaty so it could accommodate all countries,” said Solomon, who added that the United Nations (UN) Charter also does not include a withdrawal clause as it is “based on the principle of the importance of universality for that instrument”.

Meanwhile, WHO Director-General Dr Tedros Adhanom Ghebreyesus appealed to the US to stay in the WHO, saying that it was not safe for the US or for the world that it was outside the fold.

“It is not really the right decision. I want to say it bluntly, because I believe there are many things that are done through WHO that benefit the US. The US cannot be safe without working with WHO,” Tedros told a media briefing on Tuesday.

“It’s not about money. I’m not saying money doesn’t matter, but what matters most is solidarity, cooperation and for the whole world to prepare itself for any eventualities to a common enemy, like a virus like COVID-19. We need cooperation and solidarity for that.”

In 2022/ 23, the US contributed $1.284 billion to the WHO, with voluntary contributions to a range of programmes including pandemic preparedness.  In 2024-2025 the total sum was supposed to be $750.9 million, including the $260.6 million in assessed fees, as well as another 490.3 million in voluntary donations, committed during the previous administration of former President Joe Biden.  WHO has confirmed that the assessed contributions remain unpaid, in violation of legal agreements.  Asked by Health Policy Watch for further clarifications on the status of the other $490.3 million, a WHO spokesperson did not comment.

US 2024-25 commitments to WHO

With the loss of its largest donor, WHO had to implement drastic financial reforms to stay afloat, cutting posts by around 22%.

“The senior management is reduced by half, the middle management department reduced by half, and then that goes all down to the expert level, and we have made all the adjustments based on the prioritisation process we have set for ourselves,” said Tedros.

The body has raised three-quarters of its budget for 2026/27, said Tedros claiming that the financial turbulence has “stabilised” – even though a $1.05 billion funding gap remains.

He added that countries’ membership fees, “assessed contributions”, would make up 50% of the WHO’s budget by 2031, as agreed by the World Health Assembly in 2022 and this would also assist with financial stability.

-Updated 15.1.2026 with further WHO financial details.

Image Credits: WHO.

The new US EPA ruling on power plant emissions noted the health benefits of stricter regulations, but failed to assign monetary value for those benefits.

While the US Environmental Protection Agency (EPA) will still consider the health benefits of emissions regulations, it will no longer publish estimates of the economic costs of deaths, illness and disability from unsafe air pollution levels.

The US EPA, whose path-finding work on air pollution’s health impacts helped set standards internationally, will no longer put dollar amounts to the human health toll of the most hazardous air pollutants, PM 2.5 and ozone, in the course of setting new regulations or assessing the health harms of potentially polluting energy projects, the agency signalled on Monday. 

The sea change in four decades of policy was included in a new economic assessment of new emissions standards for gas turbines, which fine-tunes and strengthens slightly regulations on nitrogen oxide (NOx) emissions, but avoids setting explicit limits for emissions of fine particles, PM2.5, widely considered the most health-hazardous air pollutant.  

The costs to industry of the updated rule will amount to roughly $22.6 million annually, the assessment states. But it refrains from making any monetary estimate of health costs and benefits, stating:  

 “The EPA is no longer monetizing benefits from PM2.5 and ozone but will continue to quantify the emissions until the Agency is confident enough in the modeling to properly monetize those impacts.” 

A break from quantifying health benefits

Dr Maria Neira, former WHO director for Public Health, Environment and Social Determinants of Health highlights the $8.1 trillion is the current cost of air pollution to global GDP at a 2025 conference.

Since the 1990s, the EPA included detailed health-related benefit estimates – such as the costs saved from avoiding hospitalizations from asthma attacks, fewer lost workdays and school absences, as well as assigning a monetized value to avoided premature deaths. 

Quantifying the health benefits in dollar terms allowed for a comparison between the costs and benefits of pollution mitigation and compliance with air quality regulations on an even playing ground, advocates have long maintained. 

Estimating savings in medical costs, productivity and avoided deaths – made clear that many air rules delivered billions in net benefits over a period of a decade or more, even when industry costs were substantial. 

The new policy falls into line with industry complaints that current economic models, used by scientists and health economists around the world, overstate the benefits of air pollution mitigation – while underestimating the costs to business.   

EPA calls past methods ‘erroneous’ 

EPA

The new EPA rule, which was first reported on by the New York Times Monday,  defended its change, describing its mission to “rectify this error.”

Dropping  the monetary benefit analysis, is meant to clarify “uncertainties” in past EPA assessments, according to the agency. 

Buried in the technical jargon of the agency’s newly released power plant emissions analysis and regulation is a shift from precedent in how the EPA will approach cost-benefit analysis. 

 “Historically, however, the EPA’s analytical practices often provided the public with a false sense of precision and more confidence regarding the monetized impacts of fine particulate matter (PM2.5) and ozone than the underlying science could fully support, especially as overall emissions have significantly decreased, and impacts have become more uncertain.”

It goes on to say: “Therefore, to rectify this error, the EPA is no longer monetizing benefits from PM2.5 and ozone but will continue to quantify the emissions until the Agency is confident enough in the modeling to properly monetize those impacts.”

Slippery slope to looser standards

In a post on X that followed on the New York Times story, EPA administrator Lee Zeldin said that the agency will continue to calculate health costs of air pollution – even if it doesn’t attach a dollar sign to those costs. 

“EPA will still be considering lives saved when setting pollution limits,” said Zeldin in his post. 

The turbine policy rule change, however, includes no analysis of health benefits or costs from alternative emissions strategies. 

However nuanced the arguments may be, critics also argue that dropping the economic assessment of the health costs and benefits of air pollution mitigation from the EPA toolkit ultimately weakens the policy case for stricter standards in an agency that has long been regarded as the gold standard. 

“By foregoing the opportunity to monetize the health impacts of air pollution, the EPA will lose insight which is key to inform sound financial and health-promoting decision making,” said Dr Marina Romanello, executive director of the Lancet Countdown commission on climate and health, in a statement to Health Policy Watch. “The quantification of health impacts alone is not sufficient – translating this into monetary terms is the key step to incorporate these impacts into decision making.”

This makes some in the field worry that the EPA could drop accounting for broader health impacts next.

The adverse health impacts of soot and smog pollution are well documented and for decades, the EPA has accounted for them when setting safeguards,” said Amanda Leland, executive director of the Environmental Defense Fund in a social media post. “Now, the agency is set to stop factoring in those enormous health benefits while still counting costs to corporations.

“At a time when climate change is driving more of the pollution that makes us sick, this decision to ignore the data doesn’t make the problem go away—it only makes it harder to address.”

Dangerous global precedent 

And in the international space, clean air experts in Asia and elsewhere worry this shift could undermine emission standards in the Global South. 

“This sets a dangerous global precedent that could weaken the adoption of stronger environmental protections. It is crucial that this shift does not influence or undermine the air quality and emission standards currently taking shape across the Global South,” Anumita Roychowdhury, executive director, at the Centre for Science and Environment in New Delhi, told Health Policy Watch.

“It removes the primary justification for essential environmental standards. By focusing solely on industrial compliance costs, the EPA has created a regulatory environment where significant public health harms are ignored in favour of corporate profits.

“This decision to stop calculating the health impacts of air pollution and the associated life-saving benefits in the rule making process by the EPA places millions of Americans at risk,” Rowchowdhury said.

Former World Health Organization Chief Scientist Soumya Swaminathan echoed the sentiment, telling Health Policy Watch: “The EPA was a fine example of a science based agency, that led in environmental health regulations globally.”

Swaminathan is currently chair of the M S Swaminathan Research Foundation, as well as a Co-Chair of the Our Common Air, a global initiative

Air pollution costs US over $790 billion annually – previous EPA data  

Infographic: More Americans Exposed to Spikes in Air Pollution | Statista You will find more infographics at Statista

Ground level ozone and particulate matter (PM2.5), the two leading air pollutants that cause health harms, together account for the majority of the 135,000 air pollution-related premature  deaths in the United States, according to the US State Department website.

As of the time of this publication, the State Department website still cited  previous EPA estimates of air pollution’s health costs and monetary benefits of cleanup, stating “The EPA estimates that for every dollar invested in cleaning the air, 30-90 dollars are returned in improved health and economic productivity. Reducing air pollution is an economic accelerant.”

“The World Bank found that air pollution costs the U.S. economy over $790 billion per year or approximately 5% of our GDP in economic welfare losses. Air pollution costs the world economy over $8.1 trillion per year, or 6.1% of global GDP,” the State Department website adds.  

PM2.5, typically emitted by power plants and car exhaust, travels deep into a person’s lungs and into the bloodstream. 

In the short-term, breathing polluted air can trigger asthma, coughing, and respiratory distress.  Chronic exposures lead to the build up of plaque on arterial walls, more blood clots, constricted blood vessels and higher blood pressure – all contributing to a heightened risk of heart attack and stroke as well as cancers. 

PM 2.5 pollution is also linked to a host of conditions starting from birth: pre-term birth and low birth weight, reproductive stress, heart disease and lung cancer, and even dementia and cognitive decline. 

“Air pollution is a silent killer,” said Romanello who also researchers climate change and health researcher at University College London. “This not only affects people’s health, but also the economy, making people sick, reducing their capacity to work, increasing health bills, and affecting the economy as a whole.”

Huge wins since 1970 Clean Air Act under threat?

The US saw huge wins in cleaning up its air following the passage of the landmark 1970 Clean Air Act.

While PM2.5 levels have declined sharply in past decades, hot spots remain. Ground-level ozone (O3), which forms when nitrogen oxide (NOx) emissions and other volatile organic compounds are exposed to sunlight, has remained a major problem – associated with asthma and other chronic respiratory issues, as well as reduced crop production.

Meanwhile, under the new administration of President Donald Trump, tensions between government and environmental groups escalated – including with the appointment of Zeldin as EPA administrator.  

In March 2025, the EPA unleashed the first in a series of sweeping regulatory changes on pollution emissions with Zeldin saying “[t]oday is the greatest day of deregulation our nation has seen. We are driving a dagger straight into the heart of the climate change religion to drive down cost of living for American families, unleash American energy, bring auto jobs back to the US and more.” 

Some take a wait-and-see attitude on EPA policy change

Some experts noted that dropping the monetary value on the health benefits of air pollution regulation may not be as dramatic as advocacy groups warn.

“I’m not convinced yet that this will make a big difference – but it will likely mean more court cases with less complete information,” Michael Brauer, a Canadian expert affiliated with the University of Washington-based Institute for Health Metrics and Evaluation (IHME). IHME’s Global Burden of Disease assessments have regularly ranked air pollution as one of the world’s leading risks to health.  

“The Clean Air Act (CAA) still requires only consideration of public health, not cost, in setting national ambient air quality standards,” said Brauer. 

“Now, it looks like they will still do cost analyses, but just not quantify any benefits – still, none of this changes the basic CAA requirements.

“This does not preclude them from assessing health impacts and in the setting of standards for criteria air pollutants, public health protection and not cost is the requirement under the law.  Perhaps EPA will also raise questions about the mortality estimates themselves, but for now this is just about the costs assigned to health impacts which has always been somewhat controversial.

“Bottom line – more court cases  (and in at least some of these I’d expect that judges will want to know about costs and benefits and the EPA will not have the benefits part accounted for which may, in the end, work against changes in regulation),” said Brauer. 

Several US-based environmental health groups declined to comment publicly on the changes. The Trump administration has punished health advocacy and research institutions in the past with retaliatory funding cuts in response to criticism. In one of the most recent examples, the American Academy of Pediatrics was informed that some $12 million in federal research funds would be rescinded after it criticized HHS’s vaccine policy changes. Early in January, a federal judge ordered the funding be restored, deeming the cuts to be retaliatory. 

For Dr Maria Neira, former director of the Department of Public Health and Environment at the World Health Organization, the fact that the EPA still acknowledges its mandate to monitor the health effects of air pollution is a positive. “Protecting the health of people is one of the biggest, most beautiful and incredible missions for all of us to come together around,” said Neira, in a statement to Health Policy Watch. “Of course, we need to protect the economy, but the two things can be done together.”

This story was updated 14 January to inlcude additional expert reaction.

Chetan Bhattacharji and Elaine Ruth Fletcher contributed to this report.

Image Credits: Ella Ivanescu/ Unsplash, AP/Sierra Club.

Sugary drinks have become popular in Africa, and are driving NCDs including obesity and diabetes.

Governments should “significantly strengthen” taxes on alcoholic and sugary drinks as these products are getting cheaper, fueling obesity, diabetes, heart disease, cancers and injuries.

This is according to the World Health Organization (WHO), which issued two reports on taxing sugary drinks and alcohol on Tuesday, including how countries are implementing these.

“In most countries, these taxes are too low to be effective, poorly designed, not adjusted regularly, and rarely aligned with public health objectives,” WHO Director General Dr Tedros Adhanom Ghebreyesus told a media briefing on Tuesday.

“As a result, alcohol and sugary drinks have become more affordable, even as diseases and injuries associated with their consumption continue to place growing strain on health systems, families and budgets.”

Only 14% of countries adjust taxes according to inflation, allowing health-harming products to become steadily more affordable. 

Tedros also warned that health taxes “are not a silver bullet” or simple to introduce: “They can be politically unpopular, and they attract opposition from powerful industries with deep pockets and a lot to lose. But many countries have shown that when they’re done right, they’re a powerful tool for help.”

Sugary drink taxes are ‘too low’

WHO economist Anne-Marie Perucic

In the case of sugary drinks, at least 116 countries tax these, but there are several weaknesses, the biggest being that taxes are too low, according to the WHO report on sugary drinks taxes.

WHO economist Anne-Marie Perucic said that the average tax is around 9%. The average tax on a 330ml can of soda is merely 2,4%, according to the report.

“That’s very low, because if we compare it with [the tax on] tobacco products, on average it’s about 50% to 60%.”

Some countries only tax sodas, meaning that fruit juices, sweetened milk drinks, and ready-to-drink coffees and teas high in sugar escape taxation. Sweetened milk products are the least likely to be taxed.

Since 2013, consumption of sugary drinks has increased globally by 14%, and the most popular brands have become cheaper over the last three decades in most countries, according to WHO.

But several countries have had successes. Tedros reported that a sugary drinks tax introduced in the United Kingdom in 2018 “reduced sugar consumption, generated £338 million in revenue in 2024 alone, and has been associated with lower obesity rates in girls aged 10 to 11, especially in the most deprived areas.”

Meanwhile, Mauritius recently doubled their tax on sugar-sweetened beverages, said Perucic.

No tax on wine in 25 countries

Alcohol abuse has a serious impact on both the drinkers and communities.

“Alcohol consumption is one of the leading risk factors for noncommunicable diseases (NCDs) worldwide. It is also a risk factor for poor mental health, injury and poisoning,” according to the WHO report on alcohol taxes.

At least 167 countries levy taxes on alcoholic beverages, and 12 ban alcohol entirely. 

Most countries use volume-based excise taxes for beer and wine, and excise taxes for spirits based on their alcohol content.

“The global median excise tax shares are low for both beer (20.9% of retail price)and spirits (28.4% of retail price),” according to the WHO.

Wine is untaxed in at least 25 countries, mostly in Europe, despite clear health risks. WHO recommends that alcohol taxes should apply to all alcoholic beverages “to avoid incentivising undesirable substitutions “.

Meanwhile, “alcohol has become more affordable or remained unchanged in price in most countries since 2022, as taxes fail to keep pace with inflation and income growth,” according to WHO.

One of the few success stories for alcohol taxes is Lithuania, where “a major tax increase on alcohol in 2017 was associated with an almost 5% reduction in all-cause mortality the following year,” according to Tedros.

Taxes are a win-win

Dr Jeremy Farrar, WHO Assistant Director-General

WHO Assistant Director-General Dr Jeremy Farrar added that “the evidence from tobacco is obviously extremely strong that if taxation is increased, consumption reduces” and that “we can anticipate from the existing evidence that this will be true for alcohol and sugary drinks as well”.

Farrar described high taxes on unhealthy products as “a win-win on every aspect”, encouraging people to lower their consumption of these products, preventing non-communicable diseases (NCDs) and enabling governments to raise revenue.

Alison Cox, the NCD Alliance’s director of policy and advocacy, described well-designed health taxes as a “triple win”, bringing about “better health outcomes, stronger public finances, and reduced long-term costs”. 

However, she said that the pushback against including tax targets in the United Nations (UN) Political Declaration on NCDs and mental health, which was recently adopted by the UN General Assembly, “reflects the continued influence of health-harming industries like producers of tobacco, alcohol and sugar-sweetened beverages”. 

Cox added that some governments framed health taxes as external interference in their national sovereignty.

“These sovereignty arguments can act as dog-whistle language obscuring the reality: health taxes can support national autonomy by increasing capacity to respond to domestic health and fiscal challenges on their own terms,” said Cox.

“They protect population health while internalizing the social and economic costs of harmful products to the industries who create them – costs that would otherwise be externalized onto individuals, families, and overstretched public systems.”

Last July, WHO launched its 3 by 35 Initiative to increase the real prices of any or all of three health-harming products – tobacco, alcohol, and sugary drinks – by at least 50% by 2035 through tax increases, while taking into account each country’s unique context.

Image Credits: Heala_SA/Twitter, Artem Labunsky/ Unsplash.

Thick forests once contained rainfall and mudslides in northern Pakistan, but the hillsides have been stripped of trees.

ISLAMABAD, Pakistan – Along the winding road to Babusar Top, a favourite summer tourist spot in northern Pakistan, there was once a thick forest that shielded the slopes and cooled the air. 

Today, these hillsides are bare, stripped of trees that took a century to mature. So when torrential rains arrived in August, torrents of water roared down the unclothed slopes, sweeping away homes and roads in catastrophic flash floods.

The monsoon rains triggered the floods that submerged villages, killing more than 300 people and displacing hundreds. In Khyber Pakhtunkhwa’s Buner and Mansehra districts, whole villages were washed away in hours. Around 1.6 million people in the province were affected, and a further 356,000 people in neighbouring Gilgit-Baltistan

“Deforestation is the main reason that the cloudbursts at Babusar caused so much destruction,” said Muhammad Hanif, a community development officer at the Khyber Pakhtunkhwa Forest Department. 

“What was once forest is now just barren land. Not a single tree is left,” he said.

Hanif explained to Health Policy Watch that forest cutting has accelerated since 2017, often justified by policies allowing logging on private property. Combined with rising demand for fuelwood in mountain areas, weak law enforcement, and powerful timber “mafias”, the result is a landscape more vulnerable than ever to extreme weather.

Forests lost, futures at risk

Pakistan has one of the world’s lowest levels of forest cover — only about 5.4% of its total land area. Each year, roughly 11,000 hectares are lost to fire, land conversion, and logging. 

The consequences are immediate in northern regions such as Khyber Pakhtunkhwa and Gilgit-Baltistan, where deforestation has removed the natural barriers that absorb rainfall and prevent soil erosion.

“When trees are cut, climate change becomes not just a global issue but a very local one,” Hanif said. 

“Flash floods, landslides, and even rising temperatures are all connected. But enforcement against illegal logging is nearly impossible unless the local community is part of the solution,” he said.

The lack of alternative energy sources only deepens the crisis. Many mountain households rely on wood for heating and cooking, further depleting precious forests. 

“An alternative like LPG must be given to people, otherwise the forests will continue to disappear,” said Hanif.

Crushing mountains, crushing ecosystems

Across Khyber Pakhtunkhwa and Gilgit-Baltistan, mountains are being blasted and ground into gravel to fuel Pakistan’s construction boom.

Deforestation is only one part of the story. Across Khyber Pakhtunkhwa and Gilgit-Baltistan, mountains themselves are being blasted and ground into gravel to fuel Pakistan’s construction boom.

“Mountain and hill crushing devastates landscapes,” warned Aisha Khan, a climate activist and the chief executive officer of the Mountain and Glacier Protection Organization

“It removes the vegetation and topsoil that protect slopes, accelerating soil erosion and making floods and landslides more likely.”

Pakistan is home to over 13,000 glaciers – more than anywhere outside the polar regions. Yet unchecked stone crushing and quarrying destabilize fragile ecosystems, threatening both biodiversity and the glaciers that provide water to millions.

“There are more than 3,000 glacial lakes in Pakistan, with at least 33 classified as highly volatile,” Khan noted. “Crushing activities worsen these risks, increasing vulnerability for seven million people living downstream,” she said. 

Air pollution adds another layer of harm. Dust from crushers worsens respiratory health and may even disrupt regional climate patterns. Nationwide, air pollution contributes to an estimated 128,000 premature deaths annually.

Post-traumatic stress after the floods

Dr Ahsan Naveed, a clinical psychiatrist, set up mental health camps in the region after the floods.

Environmental devastation in Pakistan is often discussed in terms of economic loss and infrastructure damage. But the mental health toll is harder to quantify, just as devastating, and rarely addressed in national climate policies. 

“Climate change in the Khyber Pakhtunkhwa region is absolutely creating mental health issues,” said Dr Ahsan Naveed, a clinical psychiatrist who set up mental health camps in the region after the floods. 

“Come visit Beshonai in Buner or Neelmand in Mansehra — you’ll see the grave impact yourself.”

For survivors of last August’s floods, the scars are not just physical.

“After the floods, hundreds died, and the survivors experienced acute stress reactions,” recalled Naveed. “Within weeks, many developed post-traumatic stress disorder (PTSD).”

Naveed described children haunted by flashbacks, mothers numbed by grief, and families unable to sleep for fear of the next storm. Symptoms ranged from irritability and insomnia to emotional detachment.

For many flood survivors, every dark cloud brings fear. Repeated disasters erode community resilience, leaving people trapped in cycles of trauma. Children grow up in uncertainty, women face compounded stress as caregivers, and displaced families struggle to rebuild their lives.

After the floods, Naveed’s team offered crisis interventions, from psychological first aid to art therapy for children. 

“We even created a space called Ijtimai Duwa Hujra, where communities could gather, share their trauma, and heal together,” he explained.

At first, villagers resisted mental health treatment, but psycho-education and the involvement of local leaders broke down the stigma. 

“Now people call us for help themselves,” Naveed said. “It shows how deep the need is.”

Air pollution challenges

Pakistan and other countries in blue have experienced the biggest increases in air pollution over the past decade, while China and France saw the biggest declines. (State of Global Air report 2025.)

Air pollution has also become a critical environmental and public health issue in Pakistan, particularly in major cities like Lahore, Faisalabad, Gujranwala and Karachi. 

According to global air quality rankings, several Pakistani cities now rank among the most polluted in the world.

The rising pollution levels to a combination of factors, including emissions from heavy traffic, smoke from factories and brick kilns, agricultural residue burning and the broader impacts of climate change.

In response, the government has taken a series of national initiatives, including implementing and enforcing environmental regulations, establishing air quality monitoring stations and developing a smog management policy. 

The Punjab government has even introduced modern anti-smog guns across key urban areas of the province. Speaking at the launch event in Lahore, Chief Minister Maryam Nawaz stated that the technology has been tested internationally and is now being deployed in Lahore and other smog-affected cities. 

The anti-smog machines are designed to spray water into the air to suppress harmful airborne particulate matter (PM2.5 and PM10).

Punjab’s Senior Provincial Minister, Marriyum Aurangzeb, acknowledged that “smog has now become a public health emergency.” 

She said, as part of the new measures, an AI-powered air quality monitoring and forecasting system is also being introduced. This system will provide real-time data and predictive insights on air quality, allowing for timely interventions.

Laws on paper, loopholes in practice

Pakistan is not without environmental laws. The Forest Act of 1927, the Pakistan Environmental Protection Act of 1997, and provincial mining concession rules all regulate forest management and quarrying. The National Climate Change Policy of 2021 also emphasizes conservation.

But Bina Shahid, a lawyer working for environmental justice in Pakistan, points out that these laws are poorly enforced. “Illegal logging and mountain quarrying continue unchecked due to weak institutions, corruption, and political interference,” she said. 

“Local mafias often operate with impunity because of political patronage,” said Shahid. 

She highlighted multiple governance gaps: minimal fines that fail to deter violators, lack of public participation in decision-making, and Environmental Impact Assessments (EIAs) that are bypassed or poorly conducted. 

“Decentralization after the 18th Amendment gave provinces responsibility, but without capacity-building,” she noted. “Many simply lack the expertise to monitor effectively.”

The result is a legal framework that looks strong on paper but is weak in practice, leaving forests and mountains defenseless against both logging mafias and stone-crushing companies.

Stripping away natural defenses

The gravel mines have removed all the vegetation that can hold rain, making landslides inevitable, particularly during heavy rami/

The consequences of weak enforcement are stark. Without trees, hillsides cannot absorb rainwater. Without glaciers, rivers run dry.

“Deforestation and mountain crushing directly strip away Pakistan’s natural defenses,” Shahid warned. 

She said they remove buffers that regulate ecosystems, leaving communities exposed to floods, landslides, and rising temperatures.

This ecological imbalance has cascading effects — from food insecurity and biodiversity loss to increased displacement and migration. And as each disaster compounds the next, the mental health burden on communities grows heavier.

In the northern valleys of Khyber Pakhtunkhwa and Gilgit-Baltistan, communities live with the knowledge that the next flood or landslide could come at any season. Bare hills and crushed mountains stand as silent warnings of what is lost — and what is still at risk.

Court orders and future action

Last June, Khyber Pakhtunkhwa’s top court ordered the provincial government, particularly its Environmental Protection Agency, to enforce environmental protection laws and take strict action against violators. The court made it clear that no activity with adverse environmental impacts could proceed without a valid approval.

Meanwhile, appearing before the parliamentary committee on climate change earlier this month, Khyber Pakhtunkhwa’s Environment Secretary Shahid Zaman reported that the forest coverage in the province has improved, a claim verified through third-party assessments. 

He told lawmakers that monitoring of harvesting operations was ongoing, with seizures of 2.3 million cubic feet of timber and more than 360 vehicles as part of the government’s forest protection policy.

Zaman added that a comprehensive plan was in place to address environmental challenges and was showing “positive results.”

Gilgit-Baltistan officials also briefed the committee, stating that while forest land remained largely protected, extensive degradation had occurred in the 1980s due to sectarian violence and weaknesses in law and order. They urged constitutional protection for forests and sought federal technical support, particularly in digital monitoring systems.

Possible solutions

Despite the grim picture, experts agree that solutions exist. Aisha Khan advocates for strict enforcement of zoning laws, mandatory environmental impact assessments, and investment in sustainable alternatives like recycled construction materials and green building techniques.

Shahid called for harmonizing forestry and mining laws across provinces, raising penalties, and using technology like satellite monitoring to track illegal activities. She also urged greater citizen participation and independent oversight bodies to hold both government and private companies accountable.

Hanif, from the Forest Department, emphasized community involvement. “Without locals, enforcement is impossible,” he insisted. 

“We need to provide them alternatives energy for cooking, livelihoods that don’t depend on timber, and a sense of ownership in protecting forests.”

And for Naveed, mental health must become integral to climate policy. “Every disaster is not just physical — it is psychological,” he said, stressing that communities cannot be rebuilt without healing the minds of those affected by climate change.

The intertwined crises of environmental degradation and mental health demand urgent attention. As forests vanish and mountains disappear, Pakistan is not only losing its natural heritage but also the resilience of its people.

Without decisive action, the country faces a future where disasters come faster, hit harder, and leave deeper scars — both on the land and on the human spirit.

Image Credits: Rahul Basharat Rajput, HEI/State of Global Air .

Dr. Garry Aslanyan (left) with with Alex Brewis
Dr. Garry Aslanyan (left) with with Alex Brewis

Stigma remains one of the most under-examined yet damaging forces shaping global health policy and practice, according to anthropologist Alex Brewis, who argues that shame-based approaches often undermine the very outcomes health interventions aim to achieve.

In a recent episode of Dialogues, a special program of the Global Health Matters Podcast hosted by Dr. Garry Aslanyan, Brewis said stigma should be removed entirely from the public health toolkit.

“The most effective way to undo the damage of stigma within public health is to prevent it from happening in the first place,” Brewis said. “Stigma should not be used in any way for any reason to promote public health.”

Brewis, Regents and Presidents Professor at Arizona State University, co-authored Lazy, Crazy, and Disgusting: Stigma and the Undoing of Global Health, which examines how moral judgments attached to traits such as body size, mental illness, or sanitation practices strip individuals and communities of power and opportunity.

“Stigma is really about applying moral meanings to an otherwise arbitrary trait and using that as a way to devalue some people relative to others,” she said, noting that stigma produces humiliation and shame and is “physiologically stressful,” with emerging evidence of intergenerational effects through epigenetics.

Drawing on fieldwork in Mozambique and Micronesia, Brewis highlighted how sanitation interventions can backfire when they ignore local realities. In Pemba, Mozambique, open defecation was viewed as “social and practical,” while latrines were seen as burdensome or unsafe. In Kiribati, imported toilet blocks were rejected as unhygienic, ultimately left unused.

Brewis also addressed global obesity campaigns, arguing that decades of individual-blame messaging in countries such as Samoa have plateaued health outcomes while intensifying stigma.

“It’s been a cacophony of anti-fat messages for decades,” she said.

The solution, Brewis emphasised, lies in structural awareness and empathy.

“The solution to stigma is empathy,” she said. “Just about sums the book up.”

Listen to the full episode:

Image Credits: Global Health Matters Podcast.