In its first guidelines ever for Ebola treatment, the World Health Organization (WHO) advises using two monoclonal antibodies — mAb114 (Ansuvimab®, also known as Ebanga®) and REGN-EB3 (Inmazeb®) — that were first approved by the US Food and Drug Administration for use against the Zaire ebolavirus species in 2020. WHO says its “strong recommendations” for […] Continue reading ->
As the first monkeypox case involving a human-to-dog transmission reported, the World Health Organization (WHO) said more than 35,000 recently confirmed cases of monkeypox were accompanied by 12 deaths in 92 nations and territories, including almost 7,500 from last week alone. That made for the second consecutive week with a 20% increase, WHO Director-General Dr […] Continue reading ->
Top executives at Bavarian Nordic, which makes the world’s only monkeypox vaccine, avoided news media in the face of a worldwide shortage of their product. But SIGA, the company behind the antiviral treatment Tecovirimat (TPOXX™), has not been so shy. In an exclusive interview, SIGA’s CEO, Phillip Gomez, says the small, speciality firm is  prepared […] Continue reading ->
In the aftermath of a national health emergency declaration for Monkeypox, the United States has now decided to split the approved MVA-BN vaccine into five doses in an effort to stretch supply.  Some experts, however, have warned that the plan may backfire if health workers are not sufficiently trained in the intradermal skin-based jab technique […] Continue reading ->
LEIDEN – Pandemic preparedness rests on having a robust surveillance system to identify health threats – something that is still “rudimentary” in many African countries, says Professor Salim Abdool Karim, a South African infectious diseases epidemiologist. Describing monkeypox as a threat to health security in Africa, Karim said that it was important that health services […] Continue reading ->
The United States is considering shifting to intradermal injections of Monkeypox vaccine that could potentially stretch one dose of the approved MVA-BN vaccine, available only in limited quantities, into five doses, said US Food and Drug Administration Commissioner Robert Califf on Thursday. He was speaking at a press briefing minutes after Xavier Becerra, US Secretary […] Continue reading ->
The Huanan Wholesale Seafood Market in Wuhan, China, was the epicenter of the early outbreaks of SARS-CoV2, a new, peer-reviewed study asserts, following its examination of early COVID-19 cases in the region and environmental samples originating from the market.  The study, published by Science Magazine, reinforces the theory that the emergence of SARS-COV2 occurred via […] Continue reading ->
About 10% of people with Monkeypox require hospitalization and children are at the highest risk of severe disease, says WHO. Meanwhile, there are only about 1 million doses of the EMA and US FDA-approved MVA-BN vaccine readily available today across the globe – but that vaccine is also untested against monkeypox at large scale. The […] Continue reading ->