Can Smarter Subsidies Curb An Unhealthy Appetite For Fishing? 02/07/2020 Svĕt Lustig Vijay 59.5 million people depended on fisheries and aquaculture in 2018. In the past three decades, global fish consumption has surged by a stunning 122%. Yet today, only 66% of global stocks are fished within sustainable levels, in comparison to 90% in the 1970s. “There is no healthy planet without a healthy ocean, and the healthy ocean is currently in decline”, said Peter Thomson at a conference Tuesday on overfishing co-hosted by Geneva Environment Dialogues and the World Economic Forum. “There are too many boats chasing too few fish.” Marine Ecosystems Feed People & Generate Jobs If more sustainable fishing policies aren’t adopted now, marine ecosystems will bite us back with devastating economic and health consequences. Here’s why: Livelihoods – 59.5 million people depended on fisheries and aquaculture in 2018. Nutrition – Fish is a major protein source for some 3.3 billion people around the globe, accounting for one-fifth of global animal protein consumption, said Keith Rockwell, a WTO official at Tuesday’s event. How to Combat Overfishing It is possible to reduce overfishing while still supporting the fishing sector, which is so important to health and livelihoods. One of the key ways to achieve that is to re-think how fisheries are subsidized. In 2009, global fisheries received a whopping $35 billion in subsidies, but 22% were geared towards making fuel cheaper for fishers – an “alarming” figure, said executive director of the Global Tuna Alliance Tom Pickerell, as policies that subsidize fuel are the “most likely” to promote overfishing, as well as illegal, unregulated and unreported (IUU) fishing, according to research by the Organisation for Economic Co-Operation and Development (OECD). Another drawback of fuel subsidies is they tend to favour big businesses, who can more easily access the subsidies, while providing little benefit to fishermen themselves, particularly small boats and businesses in low income countries, who fish closer to shore and use less fuel. Other policies that also promote overfishing and illegal or unreported fishing are those that subsidize gear or bait – also mostly accessible to big fishing enterprises. “Fishing subsidies disproportionately benefit big businesses, which generally only really provide jobs and significant incomes to few people”, said Pickerelll. “Illegal fishing is a crime, and yet we have public funds being spent in the form of subsidies to support [overfishing and IUU fishing]. It’s just not rational”, said Thomson. Smart Subsidies for a Sustainable Future Subsidies that support efficient business operations, develop human capital and help fishers deal with disasters can all prevent overfishing while delivering significant benefits to fishers, according to the OECD. These include programmes that hone fishers’ business or operational skills. The OECD estimates that, if $US 5 billion in fuel subsidies were funneled towards more training of fishers, the benefits would be significant – their incomes would improve by $US 2 billion, all while reducing depletion of fish stocks. “Ensuring that fishers have access to working capital, have the skills needed for their businesses….can bring greater benefits to fishers at lower cost to governments, all while reducing the negative impact of support on the sustainability of fish stock”, according to the OECD report. An Opportunity to Upend the Status Quo – WTO Negotiations on Fishing Subsidies Five years ago, leaders from 192 countries pledged, under Target 6 of the UN’s Sustainable Development Goal (SDG) 14 on Sustainable Oceans, to prohibit subsidies that contribute to overfishing by 2020, and to eliminate subsidies that contribute to IUU fishing – such as fuel, gear and bait subsidizes. A WTO agreement regarding the elimination of these subsidies was supposed to have been reached at the WTO’s 12th Ministerial Conference in Kazakhstan, on 8-11 June 2020, but COVID-19 derailed negotiations as well as the planned conference. Last week, the WTO presented a consolidated draft text in preparation for upcoming negotiations scheduled virtually on 21 July. Their aim is to seal the debate on fishing subsidies once and for all. But the WTO agreement has been particularly complicated to negotiate for a simple reason – fish swim long distances. ”Unlike steel factories, or herds of cattle, fish swim great distances, they move in and out of territorial waters. Promoting sustainable fishing through WTO subsidy rules is extremely difficult, as the WTO is not a regional fisheries management organization. It’s not the FAO, which has a strong record of identifying [harmful] subsidies for industry and agriculture..[and which has the] means to discipline those subsidies,” according to Rockwell. The Time To Reform Fishing Subsidies is Now The WTO’s draft text provides the technical tools to do the job, but political issues still need to be resolved, says Rockwell. “For the first time in 20 years, we now have a single paper from which members can work. The text covers most all of the key areas in the negotiations, though some thorny issues will require a bit more time. There are no surprises. It is based on the work of this specific issue facilitators and proposals submitted directly by members. The text is solution-oriented. The language is clear, and Members will know precisely how and why it has evolved in the way that it has.” It’s up to Member States, but time is running out. There remain “very political issues” to be resolved, says Rockwell, and since WTO is a member-driven organization, the ministers, ultimately, will have the final say. But time is running out. “If we don’t set aside our differences in these negotiations [in July 2020], we will wake up one day and find there are no longer any fish over which to argue,” said Rockwell. ________________________________________________ Republished from Geneva Solutions. Health Policy Watch is partnering with Geneva Solutions, a new non-profit journalistic platform dedicated to covering Genève internationale. In the midst of the Coronavirus pandemic, a special news stream is published at heidi.news/geneva-solutions, providing insights into how the institutions and people in Geneva are responding to this crisis. The full Geneva Solutions platform and its daily newsletter will launch in August 2020. Follow @genevasolutions on Twitter for the latest news updates. Image Credits: FAO, UNCTAD. US Secures Most Of World’s Remdesivir For Next 3 Months; Swine Flu Variant Circulating In China Not A New Virus, Says WHO Experts 02/07/2020 Grace Ren Artist’s rendition of SARS-CoV-2, the virus that causes COVID-19 The United States has secured almost all of Gilead Sciences’ projected production of remdesivir – an antiviral that was shown to reduce hospitalization times for COVID-19 patients- for the next three months. US Health and Human Services (HHS) has secured 100 percent of Gilead’s projected production for July (94,200 treatment courses), 90 percent of production in August (174,900 treatment courses), and 90 percent of production in September (232,800 treatment courses), in addition to an allocation for clinical trials, HHS announced in a press release. But while painted as a win for United States patients, some are worried about what the supply looks like for the rest of the world. Word Health Organization Health Emergencies Executive Director Mike Ryan on Wednesday said the agency was investigating reports on the US’ allocation of remdesivir, and also closely monitoring a strain of swine flu that may have pandemic potential. “We’re aware of the reports in the media around this purchase or procurement of remdesivir stocks, and we’re obviously working through our colleagues and our partners and the access to Covid Tools Accelerator to clarify and verify this this report,” Ryan said in response to a query from the Financial Times regarding the US potentially “hoarding” remdesivir. Swine Flu ‘G4’ Variant Being Monitored Closely A swine flu variant, G4 EA H1N1, that captured headlines on Tuesday for its ‘pandemic potential’ has been monitored by WHO and health authorities since 2011, WHO Health Emergencies Executive Director Mike Ryan said Wednesday, attempting to ease fears that a pandemic flu strain could appear on top of this year’s deadly COVID-19 pandemic. “It’s important I think to reassure people that this is not a new virus. This is a virus that is under surveillance,” said Ryan, in response to a query from Bloomberg News. “We are concerned with any viruses that your potential to infect humans, we will continue with our collaboration centers and the global influenza surveillance and response system to keep this virus under close surveillance.” “It’s not an immediate threat where you’re seeing infections, but it’s something we need to keep our eye on, just the way we did in 2009 with the emergence of the swine flu,” Anthony Fauci, director of the United States National Institute of Allergies and Infectious Diseases (NIAID), told reporters Tuesday. “The WHO has been collaborating on surveillance since 2011. The most recent publication is an [analysis] of that surveillance data over that time,” said Ryan on Wednesday. The virus stirred attention after a paper published Tuesday described G4 EA H1N1 as having “all the essential hallmarks of a candidate pandemic virus.” The paper, Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection, was published in the Proceedings of the National Academy of Sciences (PNAS) journal and authored by a team from the China Agricultural University. The G4 EA H1N1 virus, part of a family of “G4” viruses that can make the jump from pigs to humans, may have characteristics of the H1N1 variant that caused the 2009 pandemic, or the deadlier variant that caused the 1918 Spanish flu, said Fauci. And “of concern is that swine workers show elevated seroprevalence for G4 virus,” the authors wrote. Some 10.4% of workers overall showed antibodies for the G4 virus, indicating they had likely been exposed to the virus at some point. The positivity rate in workers between 18 to 35 years old was almost double that. However, there were no records of active, symptomatic infection. “The likelihood that this particular variant is going to cause a pandemic is low,” Martha Nelson, an evolutionary biologist at the U.S. National Institutes of Health’s Fogarty International Center told Science News. Nelson studies pig influenza viruses in the United States and their spread to humans. But other researchers, including Robert Webster, a retired influenza researcher from St. Jude’s Children’s Research Hospital, say flu can be a “guessing game.” “We just do not know a pandemic is going to occur until the damn thing occurs,” Webster told Science News. Image Credits: NIAID, Flickr: liz west. Fateful International Energy Agency Meeting Could Set Course For Climate Friendly COVID-19 Recovery… Or Not 01/07/2020 Editorial team Wind turbines in Derbyshire, United Kingdom, generate energy. A landmark meeting hosted next week by the International Energy Agency (IEA) will bring together major powers to debate the key actions for a climate-friendly COVID-19 recovery in an online forum open to public viewing. The IEA Clean Energy Transitions Summit will be live-streamed July 9th, and bring together the world’s largest economies and developing countries, who generate 80% of global emissions. The meeting aims to develop plans to ramp up emissions-reducing projects to rapidly create new jobs in the wake of economic devastation wrought by the pandemic. Currently, major powers in attendance such as Germany, China and Indonesia already have recovery plans in the work that claim to center climate-friendly initiatives. In a move counter to the administration’s usual dismissive stance on climate, the United States will also be sending a representative to a high-level virtual summit on a ‘green’ COVID-19 recovery on 9 July. US Secretary of State for Energy, Dan Brouillette, will attend a meeting, according to the Guardian. “What kind of energy choices we make now will determine the decades to come,” IEA Executive Director Fatih Birol told the Guardian in an interview. “This will be critical for energy and climate change.” Emissions have gone down dramatically as travel and trade came to a standstill during COVID-19 induced lockdowns, with clear waters in Venice canals and blue skies over New Delhi for the first time in ages. Emissions of noxious greenhouse gases such as NO2, monitored by the US National Aeronautics and Space Administration and the European Space Agency, have decreased in major cities around the world. But there is increasing worry that economic recovery efforts will cause a catastrophic rebound in emissions if there lacks a concerted effort to center climate-friendly initiatives. Participation of Climate Dismissive Governments Key to Success A global ‘green’ recovery can only succeed if countries dismissive of climate change – such as the United States – also sign on to the recovery plans. “Even if governments do not take climate change as a key priority, they should still implement our sustainable recovery plan just to create jobs and to give economic growth. Renovating buildings, for instance, is a job machine,” Birol told the Guardian. So far the US administration has been silent regarding a ‘climate-friendly’ pandemic recovery economy, even as UN agencies, the European Union, and individual countries like Norway and Germany endorse green recovery plans. The US is set to withdraw from the 2015 Paris Agreement, a landmark deal meant to curb emissions to limit the rise of global temperatures, right before US presidential elections on 4 November, highlighting the importance of getting the major emitter on board for recovery plans now, said Birol. China’s energy minister, Zhang Jianhua, the EU commission’s vice-president, Frans Timmermans, and the UK’s business secretary, Alok Sharma, who is president of the 26th UN Conference of Parties climate talks (now postponed to next year), will be attending. Representatives from Indonesia, India, Brazil, and South Africa will also be in attendance. Image Credits: Flickr: The Roaming Picture Taker. Pfizer COVID-19 Vaccine Shows Promising Early Results; Induces Immune Response In Healthy Volunteers 01/07/2020 Grace Ren Manufacturing COVID-19 vaccine at Pfizer A COVID-19 vaccine candidate under development by pharma giant Pfizer and biotech firm BioNTech showed promise in interim results released Wednesday. The vaccine candidate, BNT162b1, was able to induce the formation of antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, in all participants who received doses between 10ug to 30ug, according to a report posted on the preprint server MedRxiv. The report has not yet been peer-reviewed. Seven days after the last injection, levels of neutralizing antibodies in those who received 10 µg and 30 µg of the vaccine 21 days apart were 1.8 to 2.8 times the level of neutralizing antibodies in recovered COVID-19 patients. “These preliminary data are encouraging in that they provide an initial signal that BNT162b1 targeting the RBD SARS-CoV-2 is able to produce neutralizing antibody responses in humans at or above the levels observed in convalescent sera – and that it does so at relatively low dose levels. We look forward to providing further data updates on BNT162b1,” said Ugur Sahin, M.D., CEO and Co-founder of BioNTech, in a press release. The study placed 45 healthy volunteers between the ages of 18 to 55 into three groups for the initial analysis. Some 24 subjects received two injections of 10 µg and 30 µg, 12 subjects received a single injection of 100 µg, and 9 subjects received 2 doses of placebo control. However, the study did not include results from adults over 65 years of age and pregnant women. Three-quarters of the subjects in the first group experienced acute low-grade fever below 100 degrees Celsius, and some experienced minor to moderate pain at the injection site. More trials must be done in order to test whether the vaccine can lower the likelihood of infection by 50%. But the preliminary results indicate that Phase ⅔ trials may be set to start in late July, as Pfizer Chief Executive Officer Albert Bourla told reporters in May. These trials may enroll up to 30,000 healthy volunteers The Pfizer vaccine is one of 14 candidates currently in human trials. It is based on messenger RNA, a single-stranded construct that carries a blueprint for a protein immune cells can then learn to attack, the same model as the Moderna vaccine candidate. The Moderna vaccine also showed promising early results, inducing neutralizing antibodies in a small group of early volunteers, but further results have yet to be released. Image Credits: Pfizer, Pfizer. World Health Organization Will Send Scoping Mission To China To Investigate COVID-19 Origins 30/06/2020 Editorial team Dr Tedros at a June 2020 press briefing The World Health Organization will be sending a mission to China on 6 July to investigate the origins of SARS-CoV-2, the virus that causes COVID-19, WHO Director-General Dr Tedros Adhanom Ghebreyesus subtly announced at a Monday press briefing. The mission aims to fulfill decisions made in a unanimously passed World Health Assembly resolution in late May, which requested WHO work with World Organisation for Animal Health (OIE), the Food and Agriculture Organization of the United Nations (FAO) and countries to “identify the zoonotic source of the virus and the route of introduction to the human population, including the possible role of intermediate hosts.” “We will send a team next week to China to prepare this and hopefully it will lead to a better understanding of how the virus started and what we can do in the future to prepare for it,” said Dr Tedros on Monday, in response to a query from a Brussel Times journalist following-up on the status of actions outlined in the resolution. Two WHO experts will be sent on the initial scoping mission; an expert in animal health and an epidemiology expert with a background in investigating epidemics in the field, WHO Health Emergencies Executive Director Mike Ryan added on Wednesday. While researchers largely believe that the virus jumped the animal-human barrier at a wet market in Wuhan, China, some have posited that the virus may have escaped from a high level virology lab within miles of the first cluster of confirmed cases. The quiet announcement underlines the political tensions surrounding the investigation of origins of the virus, with WHO caught in an ongoing feud between China and the United States. United States President Donald Trump has repeatedly slammed the World Health Organization for supposedly catering to China’s favor and delaying global responses to the pandemic, despite once praising the WHO and China response before COVID-19 reached US shores. Trump has made WHO’s supposed deference to China the main point of contention for withdrawing US support from the agency, even as the US continues to face an accelerating pandemic at home, reporting the highest numbers of new cases and hospitalizations daily. But WHO has little authority over Member States’ actions, and must balance criticising pandemic responses with retaining access to data and knowledge. The first WHO mission to China was delicately arranged at the end of January, after Chinese authorities locked down the Wuhan, a city of 11 million people, following a spike in cases due to a delayed response in early January. Since largely coming out of lockdown in May, the outbreak in China has been tightly controlled. However, new clusters of cases in Jilin province, Wuhan city, and the capital of Beijing have sparked great unease and second rounds of lockdowns. Swelling Indian National Opposition As Modi Plans To Expand Coal Mining 30/06/2020 Jyoti Pande Lavakare Coal miners in India’s resource-rich Meghalaya State. A government tribunal banned coal mining in the region in 2015. New Delhi, India – Prime Minister Narendra’s Modi’s ambitious plan to use coal to power India’s economic revival after his government’s strict lockdowns flattened the wrong curve, bringing economic growth to a halt even as the infection epidemic curve continued to rise, seems to have run into significant opposition from unexpected quarters. Since the launch of his plan earlier this month, state after Indian state has expressed disagreement with the Centre’s plan to commercially auction coal mines to the private sector, including international players. The latest to join the clamour of opposition by the states of Chhattisgarh, Jharkhand and Maharashtra, where more than half of the 41 mines are located – is the politically powerful chief minister of West Bengal, Mamata Banerjee. Indian environmentalists have also decried a seemingly desperate announcement by the government to auction off 41 Indian coal mines, opening a largely government-controlled sector up to all private investment for the first time ever – and thus greatly accelerating domestic coal production. Coal mining by Eastern Coalfields Ltd., the company that operates national coalfields in Jharkhand and West Bengal states. As of now, two government-owned mines produce over 90 % of India’s coal. Indian coal, known for its high fly ash content– and therefore pollution emissions – currently supplies about 80% of the country’s total coal needs, while the rest is imported. Coal, in turn, powers about 44% of the total energy needs, compared to oil (24%) and biomass (22%) – though the latter is often burned in highly polluting domestic cookstoves emitting climate-changing black carbon particles. Also, hydroelectric power supplies 1.4% of the economy, leaving solar and wind to supply only around 0.8% of the country’s total power needs. When it comes to electricity generation, the picture is just a little bit better. Coal powers 73% of electricity in India, while solar and wind fuel around 8% and hydro around 12% respectively, said Karthik Ganesan, Research Fellow, Council on Energy, Environment and Water. Clean air campaigners had hoped that the glimpse of blue skies, clean water bodies and nature restoring itself in the limbo provided by the lockdown of all growth engines would encourage decision-makers to choose a growth recovery path that had low environmental impact. Health and environmentalist activists had expected the government to look at growth recovery more holistically, which meant including developmental indicators like health, education and quality of life – in the spirit of the recent WHO manifesto for a healthy green recovery, which calls to put a stop to fossil fuel subsidies using taxpayer money. Unfortunately, India seems to be ignoring all of the recent health and climate warming signals – the latest being the swarms of locusts that are invading parts of the country as it focuses on coal to fuel its recovery. Ostensibly, Modi’s rationale is that the move will help make India energy self-sufficient and quickly claw back the robust growth curve that had begun to fall off even before the COVID-19 pandemic struck the country. However, investing heavily in coal also serves some of his key political alliances, some of whom – like the Adani Group – are also planning to export massive new coal reserves from Australia to India. Opposition to Modi’s Move Growing in India Existing, new, and planned coal mines in India (Credit: R. Pearce, T. Prater, S. Evans/Carbon Brief) Despite the pressing economic challenges that India admittedly does face, some leading Indian politicians are beginning to speak out in opposition to the coal mining plans – bringing this sector back into centre stage for the first time since “Coalgate,’ a coal scam that tainted the previous government a decade ago. Jharkhand state has already approached the Supreme Court challenging this auction, followed by Chhattisgarh and Maharashtra writing to the central environment minister Prakash Javadekar objecting to the auction. The latest to join the rising voice of critics is the feisty Chief Minister of West Bengal (and Modi’s bete noire) Mamata Banerjee, known for her blunt statements and ability to stand up to the central government. Last Thursday, Ms Banerjee wrote to Modi on Thursday, asking him to reconsider the decision, saying that “this policy can neither bring foreign direct investments not can it bring technologies or know-how which we are unable to access today,” and noting that global investors are more interested in renewable energy projects rather than coal, which offers low returns. None of the 41 mines coming up for auction are located in her state. Her objection is in principle and adds political weight to the growing opposition. States like Jharkhand, Maharashtra and Chhattisgarh, where more than half the mines coming up for auction are located, have already voiced opposition to this decision, citing huge environmental and social costs: “Riding on coal could spur the economy in the very short term and an extremely high ecological and social cost”, said Niraj Bhatt, Researcher in Environment and Climate Action for the Chennai-based Citizen consumer and civic Action Group (CAG), who works in the coal sector. The long term costs of promoting coal are disastrous, even in the government’s very first Climate Assessment report. The report warns of a four-fold increase in heat wave frequency and a doubling in the length of heat waves in India by 2100. “It is inexplicable why the government is prioritizing coal for fast track revival of the Indian economy since the pandemic”, given the knowledge that’s available, added Bhatt. Many local communities also are opposed to the government’s decision to privatize coal mining, fearing that this will degrade the environment. Most of the 41 coal mines in auction are in pristine forest areas. Even at the village-level, several panchayats (local governance bodies that make the fundamental building blocks of governance) have asked Modi to withdraw this auction. “Nine village panchayats from Hasdeo Arand forest region have written to the Prime-minister asking for withdrawing the auction of five coal blocks in the region for commercial mining as it would impact their livelihood and culture,” said Avinash Kumar Chanchal, a grassroots climate activist who has written on the degradation of the Singrauli coal belt and displacement of local communities. UN Secretary General Also Decries Coal Plans There is no good reason for any country to include coal in their #COVID19 recovery plans. This is the time to invest in energy sources that don’t pollute, generate decent jobs and save money. — António Guterres (@antonioguterres) June 29, 2020 United Nations Secretary-General Antonio Guterres has said there is no reason for any country to include coal in the COVID-19 recovery plans. Instead, investments should be made towards non-polluting energy sources; and opposition to a “black, coal-powered recovery” has grown in India. It isn’t clear whether this diplomatic rap on the knuckles and growing opposition will succeed in stopping the government in its polluting tracks, especially if Modi’s public statements on privatising coal mines – framed in his signature style with the bells and whistles of patriotism and nationalism for “atma-nirbharta” or self-reliance – are anything to go by. Desperate for funds and eager to kickstart a sluggish economy threatening to fall into a recession, the central government seems prepared to roadroll its way through. Its desperation stems from predictions of the most severe recession in the past the four decades – The International Monetary Fund has predicted a global annual downturn of 4.5%, though ratings firm India Ratings has predicted the Indian economy to contract by 5.3% this year. Renewable Energy Offers Untapped Potential Analysts say that the government is gambling on coal mining to generate over a million of jobs, as it is labour-intensive and rural communities are increasingly desperate for jobs following mass reverse migration since the pandemic began. Additionally, there is built-in momentum for coal power development, since it is already well-established and subsidized by the government – whereas renewables are a new game altogether, and energy storage issues still remain unresolved – as some critics claim. Activists and economists counter that government forces have ignored the potential of alternative energy sources at the current juncture: “There is huge potential to generate new jobs in renewable energy. Some analyses have estimated that more than one million jobs can be created by the renewable sector by 2022 if India can achieve its ambitious renewable target of 160GW,” said Chanchal. “The illusion of low cost energy from coal has been debunked globally. Socially, environmentally and economically, coal is very costly. It’s bad economic policy to invest in high cost options when cheaper alternatives exist today,” added Laveesh Bhandari, an economist turned environmental advocate, who works at the intersection of sustainable employment and climate change. “It’s almost as if we’re moving backwards. The whole world is moving away from coal. Several studies in India have shown the adverse effects of pollution caused by coal mining on the health of communities living within coal mining areas, especially on the respiratory system.” Even before pandemic, deaths from air pollution have been a major issue in India. In 2016, household pollution led to over a million deaths in India, according to the WHO’s Global Health Observatory; and in 2012, ambient air pollution claimed 620 000 Indian lives, with a shocking toll of over 20 million disability-adjusted life years (DALY), according to the WHO’s global assessment of exposure and burden of disease. However, now there is also the added factor of COVID-19, in which case chronic heavy exposures to air pollution will also increase vulnerability from the virus as well as mortality, said grassroots environmentalist and writer Rinchin, who goes by one name only and works with adivasis in Chhattisgarh. “Whether the Centre can still go ahead is a legal issue, but it will be bad form to go against the position of state governments. India is a federation, and something like mining that impacts not only the environment, but society itself therefore needs to be overseen, regulated and controlled by the state”, added Bhandari. India’s Ambition – Regional Energy Supplier? Coal mining in India While Modi is framing the coal auction as a move towards greater national self-reliance, the story is in fact more complex. His plan may involve ambitions to become a regional energy-producing power. It also aligns national policy with the commercial interests of close political allies – such as Indian billionaire Gautam Adani, and head of the powerful Adani group. Adani is leading the Carmichael project – a massive mining initiative to export Australian coal to India. Just last year, the Australia’s government gave the go-ahead for the project, the world’s largest open pit mine, overriding stiff opposition from Australian environmentalists. Adani plans to use the Australian coal for a new $2 billion power plant that his company is building in India, which will also produce electricity for sale in neighboring Bangladesh. Ever since Modi was the chief minister of the western state of Gujarat – Adani’s birthplace and home region – Adani and Modi were known to have close links. “The story of Adani and its Australian project illustrates why the world keeps burning coal despite its profound danger — and despite falling prices for options like natural gas, wind and solar,” the New York Times said last year. In fact, India’s coal ambitions under Modi will not just undermine existing efforts to limit climate change and worsen air and water pollution within the country, they are also likely to compromise the entire region, setting an undesirable example of fossil fuel dependency in neighbouring countries. Little Matter of Coal Gasification Air pollution in Delhi, India Then, there is that little matter of Modi’s plans for coal gasification – a technology that could further reduce India’s dependence on imports, but at an even higher level of carbon emissions – as well as potential water contamination from coal pollutants. The government’s current plan is to promote “syngas” -a substitute for imported liquified natural gas produced by coal gasification – to produce urea in fertilizer. This will not only help reduce liquified natural gas (LNG) imports but also urea imports, leading to a lower import bill and greater self-reliance. According to the Ministry of Chemicals and Fertilisers, urea is currently produced using pooled natural gas, which consists of both domestic natural gas and imported LNG. The usage of locally available coal for making fertilisers would help reduce the import of LNG, the Ministry has said. “The big question is when we have cleaner, cheaper, and sustainable renewable energy sources why do we want to invest in dirty and polluting technologies and energy sources? India is already facing a climate crisis,” said Chanchal. While natural gas is considered a lower climate emitter than coal, syngas is just the opposite. A study by Duke University found that syngas produced by coal gasification emits seven times more greenhouse gases than natural gas, making it a huge contributor to climate change. “It contaminates both surface water and groundwater, and also emits greenhouse gases. If renewable energy is available and becoming cheaper day by day, then why does the government want to start commercial mining to create coal based energy.” “Right now, the government is speaking like a climate leader but acting like a climate laggard by betting high on coal and promoting it,” added Bhatt. Mining Could Also Increase Dangerous Human-Wildlife Conflicts Dog sleeps on a bed of coal in Asansol, India Along with the climate and air pollution risks, activists have also warned that expanding mining operations in the areas up for auction could trigger increased human-wildlife conflict. “Among the 41 coal mines up for auction, most are situated in the dense forest of central India,” said Chanchal. “These forests are home to large populations of elephants and other wildlife. Some proposed coal blocks are also near tiger reserves, like in Maharashtra. “Along with vast forest destruction, coal mines will also increase the human-wildlife conflict. The implications are countless from the displacement of adivasis, to the violation of the Forest Rights Act, to public health,” said Chanchal, who has also written The Singrauli Files about the degradation of that region. “We have already seen how coal mines destroyed the rich biodiversity of places like Singrauli, Korba, and in other coal belts where thousands of adivasi and local communities were displaced, their forests, livelihood and human rights violated. They are already living with serious health crises,” he added. In a parallel move, Modi’s Ministry of Environment and Forestry also has launched an initiative to dilute existing environmental impact assessment norms for the creation of industries in pristine areas, including, but not limited to coal – a move that has been staunchly opposed by environmentalists – but action on that has been postponed by the courts until August. Modi Still Likely to Face Bureaucratic Challenges India’s Prime Minister Narendra Modi Despite the burgeoning opposition, Modi remains determined and eager to develop the private coal sector. Against the wave of new criticism he has remained silent – a typical tactic of response. However, India’s federal structure of governance may still slow down the realization of his vision considerably – giving environmentalist valuable time to mount a more organized local and global opposition. In the Indian governance model, the central government is expected to execute policy in consultation with state governments on a consensus model. More importantly, if the land is pristine forest land, as in this case, local self-governance laws and the FRA will make it challenging for it to move ahead with coal block allocation in such areas, which may still stave off this path to a quicker, but blacker, revival. “Land is a state subject, the Centre cannot go ahead without support from the states,” said Bhatt. “The implementation of the Forest Rights Act is also very crucial in these regions. The government which is promoting ‘atma-nirbhar Bharat’ should consider these concerns of local communities and take appropriate action to strengthen the self-governance of the gram sabha,” adds Chanchal. Image Credits: Environmental Change and Security Program, Flickr: Partha Sarathi Sahana, R. Pearce, T. Prater, S. Evans/Carbon Brief, Environmental Change and Security Program, Wikimedia Commons: Prami.ap90, Flickr: Partha Sarathi Sahana, Mike Bloomberg. World Surpasses 500,000 COVID-19 Deaths; Medicines Access Experts Challenge US $2340 Per Remdesivir Treatment Course Price Set By Gilead For Developed Countries 29/06/2020 Grace Ren Vial of remdesivir A six-vial five-day course of remdesivir – a promising COVID-19 treatment – will be priced at US $2340, or $390 per vial for developed countries, Gilead Sciences Chief Executive Officer Daniel O’Day wrote in an open letter on Monday. “Earlier hospital discharge [thanks to treatment by remdesivir] would result in hospital savings of approximately $12,000 per patient,” wrote O’Day. “We have decided to price remdesivir well below this value.” But the price is still high compared to the cost of manufacturing, according to medicines access experts, who say that remdesivir could be produced for below a dollar a day. Private insurers in the United States will pay US $3,120 for a five-day course, or $520 per vial. Out-of-pocket payments will be determined by individuals’ coverage plans. In 127 developing countries, Gilead has allowed generics companies to manufacture the drug, pricing a five-day course at about US $600. Cost of production for the drug can be as low as US $0.93 per day, according to a paper by Dr Andrew Hill, a senior visiting research fellow at the University of Liverpool, and his colleagues. “Gilead will turn a nice profit with its set price. Especially considering that the company has benefitted from significant government financing for the development of the drug; which apparently has not been discounted,” Ellen t’Hoen, director of Medicines, Law and Policy, told Health Policy Watch. electron microscope photo of SARS-CoV-2, the virus that causes COVID-19 “Based on publicly available data, it has been estimated that taxpayers have contributed at least $70.5 million to develop this drug,” Jessica Burry, a pharmacist at Médecins Sans Frontières Access Campaign, said to Health Policy Watch. “Additionally, contributions were made by various health organisations, including MSF, which supported clinical trials with this drug for Ebola in 2019. Patients themselves have also contributed by their participation in the trials. “Public funding and resources have contributed to the drug’s further development for COVID-19, and taxpayers will now end up essentially “paying twice” to access this treatment,” added Burry. The company could turn a US $2.3 billion profit on the “blockbuster” drug this year alone, according to a blog by Ellen t’Hoen. “This does put pharma’s lofty promises of not profiteering during the pandemic into perspective. I hope governments begin to realise that the important investments they make for the development of drugs and vaccines to respond to COVID-19 need to come with strings attached to ensure fair pricing and global access,” she said. COVID-19 Cases Surge Past 10,000,000, Deaths Reach Half A Million Meanwhile, the World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus warned on Monday that “the worst was yet to come.” Dr Tedros spoke at a press conference just as the number of deaths from COVID-19 topped half a million, and cumulative cases surged past 10,000,000. The US and Brazil continue to report around 40,000 new cases day. In the state of Texas, which saw one of the fastest rising daily case counts after reopening, hospitals in the capital city of Houston are nearing ICU capacity. Even as Vice President Mike Pence lauded the state’s reopening at a press briefing Monday, Texas Governor Greg Abbot warned that the epidemic had taken a “very swift and very dangerous turn.” Abbot shut down bars and clubs again across the state in an attempt to limit the fast-spreading virus. Remdesivir Pricing Announcement Comes On Heels Of EMA Conditional Marketing Authorization Endorsement Remdesivir, a failed Ebola antiviral, is one of the frontrunner drugs for treating COVID-19. It was shown to significantly reduce the length of hospital stay from an average of 11 days to an average of 15 days in a recent trial funded by the US National Institute of Allergies and Infectious Diseases (NIAID). However, the NIAID trial results were based on a 10-day treatment course, rather than the 5-day course that Gilead has currently priced. And studies have so far not reported any effects in reducing mortality. Still, the European Medicines Agency recently renewed their endorsement of the drug, recommending the agency give remdesivir conditional marketing authorization – a stamp of approval that many European Union countries use as guidance for approving drugs for diseases with few cures. Remdesivir is currently approved for use in Japan for COVID-19 patients. The United States Food and Drug Administration has approved the treatment for ’emergency’ use, just two days after the NIAID trial results were announced. The announcement comes just as Gilead’s promise to donate remdesivir until the end of June 2020 hits its deadline. US Health and Human Services Secretary Alex Azar announced Monday that the government had secured another half a million treatment courses of remdesivir for U.S. hospitals through September, according to an interview with “Good Morning America.” Health and Human Services will be paying the US $390 per vial price, and be responsible for allocating Gilead’s supply of remdesivir, according to O’Day’s letter. But some middle income countries that are hoping to secure their own supply of remdesivir may be out of luck, according to Burry. “Gilead has entered into license agreements with several generic companies in India, Pakistan and Egypt. The license, however, excludes nearly half of the world’s population, including most South American countries and a number of middle-income countries, such as Brazil, Russia and China,” said Burry. “Since the corporation has barely been able to supply enough quantities of this drug even to the US, it is highly unlikely that it will be able to meet the demands of all the other countries that have not been included in this license.” Brazil Signs Contract To Produce AstraZeneca & Oxford COVID-19 Vaccine Candidate; China Approves CanSino Vaccine Candidate For Military Use In a parallel development, Brazil on Saturday signed a contract with AstraZeneca and Oxford to manufacture an experimental COVID-19 vaccine candidate. Meanwhile, China approved the CanSino COVID-19 vaccine candidate for military use on Thursday. Local vaccine manufacturer Fiocruz will be producing up to 100 million doses of the vaccine overall, Brazilian authorities announced at a press briefing. The country will pay $127 million to receive material to produce 30.4 million doses in two batches in December and January, with the rest to come later. China’s Central Military Commission approved the CanSino vaccine for use by the military for a period of one year beginning 25 June 2020, according to a CanSino filing. The Academy of Military Sciences had jointly developed the vaccine candidate with CanSino. Results from a small, non-randomized trial released in May found that about 75% of people who received high doses of the CanSino vaccine candidate developed antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, after 28 days. However, the developers highlight that large, randomized control trials must be done in order to determine if the vaccine truly protects against infection by the virus. And other researchers pointed to old concerns with the Ad5 vector used in the CanSino vaccine. Previous Ad5-vectored vaccine candidates for HIV were dropped after early trials showed the experimental vaccine inadvertently increased the risk of HIV infection. This story was updated 30 June 2020. Image Credits: European Medicines Agency, NIAID, World Health Organization, NIAID. Gender-Based Violence – The “Shadow Pandemic” Of COVID-19 26/06/2020 Paul Adepoju While a face mask could provide some protection against COVID-19, the lives of many women in Africa, and elsewhere, are at the mercy of their abusers. (Photo Credit: Paul Adepoju) Ibadan, Nigeria – Twenty-two year-old Uwaila Vera Omozuwa, freshly admitted to university, had retreated to study in a church in the city of Benin, Nigeria during lockdown, when she was raped and killed on May 30. The following day, 18-year-old Barakat Bello was reportedly raped and killed in Oyo state. 29-year-old Azeezat Shomuyiwa and 21-year-old Grace Oshiagwu also suffered similar fates just days and few streets apart. In late March 2020, a video from Ghana surfaced on social media showing a boyfriend assaulting his girlfriend. As the COVID-19 pandemic continues to expand globally, African countries as well as other nations worldwide are also dealing with another related pandemic – that of gender-based violence. The stress triggered by COVID-19 lockdowns and economic uncertainty is exacerbating violent assaults, according to experts speaking at a panel last week hosted by the WHO Regional Office for Africa. Effectively, the pandemic has forced many women who are in abusive relationships to remain shut up at home with their abusers, further escalating their risks, they said. Social media responses condemning the gruesome murder and rape of Vera Uwaila Omozuwa. (Photo Credit: Youth Alive Foundation ) A “Shadow Pandemic” Gender-based violence is a “shadow pandemic” to COVID-19 said UN Women’s Executive Director, Phumzile Mlambo-Ngcuka. She noted that in Africa as well as elsewhere in the world, domestic violence hotlines and shelters are reporting rising calls for help. “Confinement is fostering the tension and strain created by security, health, and money worries. And it is increasing isolation for women with violent partners, separating them from the people and resources that can best help them,” Mlambo-Ngcuka said in a statement on violence against women and girls. “It’s a perfect storm for controlling, violent behaviour behind closed doors. And in parallel, as health systems are stretching to breaking point, domestic violence shelters are also reaching capacity, a service deficit made worse when centres are repurposed for additional COVID-response.” Africa has struggled with social attitudes sanctioning violent attacks on women, well before the pandemic began. For instance, in 2017, researchers at the University of Ghana reported that men who were in consensual unions or customary marriages remained in favour of wife beating. Police attitudes are often lax as well. Following Uwaila’s rape and murder in Benin, Nigeria, for instance, the local police initially demanded a “mobilization money” from the family to open an investigation, according to the victim’s sister, who finally led a protest to the Edo State police headquarters to trigger action – which she videotaped on Instagram. Now, in the period of COVID-19, for every 3 months lockdowns are imposed or continue, an additional 15 million extra cases of gender-based violence could be recorded worldwide, states a new report, COVID-19: A Gender Lens, by the UN Population Fund (UNFPA). And six months of lockdown could result in additional 31 million cases of gender-based violence in the world. Photo Credit: UN Women While the most extreme outcome, gender-based violence is not the only way women are suffering from lockdown restrictions, noted Dr. Natalia Kanem, UNFPA Executive Director while unveiling a new analysis by UNFPA and partners. “Millions more women and girls now risk losing the ability to plan their families and protect their bodies and their health,” she said, noting that women often cannot get to health services for basic care. “Women’s reproductive health and rights must be safeguarded at all costs. The services must continue; the supplies must be delivered; and the vulnerable must be protected and supported.” Fighting the Shadow Pandemic In Africa, political leaders have generally been reluctant to make themselves the face of campaigns against gender-based violence, the panel participants observed, recommending that Africa’s political leaders need to start speaking up now. “African leaders need to declare this situation as another pandemic and appeal to people, men, society, and those who set norms. African leaders need to speak up and recognise this is happening,” said Dr Matshidiso Moeti, WHO African Regional Director while speaking on the panel. Governments also need to make gender-violence prevention initiatives integral to economic and healthcare programmes dealing with COVID-19, she said. Matshidiso Moeti Specifically, she mentioned that police officers and health workers in African countries need to be made aware of the roles they are supposed to play in prevention of gender-based violence. For countries that are still in the dark over what to do, she noted that the government can work with men and women groups to improve the level of public education, provision of call numbers to report cases of abuse, and establishment of shelters to provide help and services to victims. “These can be part of the socio-economic response to the pandemic,” Moeti added. While most African countries now have legislation against gender-based violence, political leadership is still missing, agreed Winnie Byanyima, Executive Director of the Joint United Nations Programme on HIV/AIDS (UNAIDS). “I so rarely hear a male African leader speaking and leading on this issue. Most African leaders leave it to others, yet it is a pandemic – a silent one too,” Byanyima said. For Africa to advance in tackling gender-based violence, African leaders must be saddled with the responsibility of providing political leadership, she said. One leader that has spoken up recently was South African President Cyril Ramaphosa, a political powerful voice, as he is also the head of the African Union. Speaking to the media last week, he blamed the reopening of liquor stores as lockdown measures eased for a spate of attacks on women in that country. Those included pregnant, Tshegofatso Pule who was found hanging from a tree, Naledi Phangindawo, who was stabbed, and Sanele Mfaba whose body was later found in a Soweto township. South African campaigners note that in fact violence against women shot up from the moment the lockdowns began. The police force’s gender-based violence hotline received 2,300 calls in the first five days – nearly three times the rate prior to lockdown. Even so, Ramaphosa’s remarks were significant as this represented one of the few instances when an African Head of State has spoken out forcefully on the issue. Community-based Prevention and Education Are Key While some actions are being taken to improve Africa’s response to gender-based violence including building police and judiciary systems that understand their roles and can prosecute cases of gender-based violence, more needs to be done about awareness-raising and education that can prevent crimes from ever occurring, stressed Byanyima. “In my view, we are weakest on prevention. You need aggressive campaigns discouraging violent behaviors of boys and men, especially the way they see their masculinity and how they exercise it. That discouragement still needs to happen,” Byanyima said. Presently, this duty is largely left to civil societies and women organisations, but Byanyima noted that it is the business of the government to invest in continual campaigning in communities to change how relationships can be managed without violence. Winnie Byanyima “This is about men’s behavior – the way men are raised and see themselves as men. Tackling toxic masculinity is something that is not well invested in,” she said. Another necessary action to tackle the silent pandemic is to empower girls and women in African societies. Citing data from HIV, the UNAIDS Executive Director noted that an African girl’s vulnerability to HIV, sexual violence, unintended pregnancy and early marriage reduce by up to 50% if she is able to complete high school. But while African leaders have ratified universal basic education requiring every child to get at least primary education, two-thirds of children in Africa do not have access to secondary education. “The time for secondary education has come. We fought for universal primary education in Beijing and within ten years we have achieved it. Now we need to draw the line and say every government worth its name must put its kids, boys and girls, through high school. Not only for the knowledge economy but also for the safety and empowerment of girls and fighting gender-based violence,” Byanyima said. Story of Success: Experts Laud Rwanda’s One Stop Center For Sexual Violence Bineta Diop, African Union’s Special Envoy on Women Peace & Security, recommended African governments adopting Rwanda’s one-stop center for sexual violence. Located within the Kacyiru Police Hospital, the Isange One Stop Centre, the Isange One Stop Center has become a hub for gender-based violence survivors. At the center, survivors can access all the required services in one place and for free. The center is operated by the country’s Gender and Family Promotion, of Health, and Justice ministries in addition to the Rwanda National Police. Bineta Diop The initiative that started in 2009 as a pilot has since been expanded across the country. Rwanda now has a One Stop Centre in every district. Every day, up to 12 survivors are received at the center. “28% are survivors of intimate partner violence and 78 percent are survivors of sexual violence. Of the 78% of survivors who have been sexually assaulted, 16% are younger than 5 years,” said Daniel Nyamwasa, Commissioner of Police and Chief Infectologist Consultant at the hospital. Diop also encouraged African governments to acquire DNA testing capabilities to provide evidence that could be used to prosecute cases of rape and other gender-based violence against women and girls. Enlisting More Women in Police and Judiciary Another solution is the enlistment of more women in the police and judiciary systems across the continent which Diop said will encourage more women to approach the legal system to file complaints. She also called for the engagement of Africa’s traditional leaders. “If you want to break the patriarchal system, you have to engage the traditional system,” Diop said. However, as the number of confirmed cases of COVID-19 in Africa is increasing, African governments are also focusing on how to quickly and safely reopen their economies to minimize the impact of the pandemic. This current reality threatens the materialization of recommendations giving more attention to combating gender-based violence. But Ramaphosa, for one, has said this does not have to be the case. In his comments last week, he stressed that action can and should be taken to combat violence, despite the numerous familiar and peculiar challenges that countries across the continent are facing: “For public faith in the criminal justice system to be maintained, gender-based violence needs to be treated with the urgency it deserves by our communities working together with our police.” Cyril Ramaphosa, President of South Africa Image Credits: Paul Adepoju, Twitter: Youth Alive Foundation, UN Women. Massive Mobilization Of US $31.3 Billion Required For COVID-19 Diagnostics, Drugs & Vaccines Accelerator 26/06/2020 Grace Ren Central Laboratory at the Academician Nikoloz Kipshidze University Clinic, Tbilisi, Georgia, receives laboratory equipment for COVID-19 diagnosis. The World Health Organization aims to raise a whopping US $31.3 billion to fund the ambitious goals of the Access to COVID-19 Tools (ACT) Accelerator; a multi-stakeholder initiative that aims to develop and deploy diagnostics, drugs, and vaccines to control the virus. But so far, only $US 3.4 billion has been pledged towards the initial goals. And US $13.7 billion is ‘urgently needed’ in order to cover immediate needs, according to an investment case released by WHO on Friday. “Though these numbers sound big, they are not. If we spend billions now, we will avoid spending trillions later. The time to act is now, and the way to act is together,” said Gavi Board Chair Ngozi Okonjo-Iweala. The funding will go toward: Scaling up development and delivery of 500 million diagnostic tests to low- and middle-income countries (LMICS) by mid-2021 Delivering 245 million courses of treatments to LMICs by mid-2021, Delivering 2 billion vaccine doses, of which 50% will go to LMICs by the end of 2021. “It’s clear that because all people are at risk of COVID-19, all people should have access to all the tools to prevent, detect and treated, not only those who can afford to pay for them,” said World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus at a Friday press briefing. “We have made the principle of equitable access a simple thing to say, but a complicated thing to implement.” Dr Tedros at the 26 June press briefing More than 9 million people have been infected, and nearly half a million have so far lost their lives to the virus. The investment required in the Accelerator is less than a tenth of the loss the global economy is facing every month due to the pandemic, according to International Monetary Fund estimates. “The cost of inaction now is quite important to take into consideration,” said Philippe Duneton, executive director of UNITAID, working with the Wellcome Trust on the therapeutics pillar of the project. A good portion of the immediate investments will go towards preparing markets to absorb new COVID-19 technologies, setting up demand, manufacturing, and country capacity to roll out any new diagnostics, vaccines, or drugs. Four Investment Pillars Require Urgent Funding The ACT Accelerator operates under four main pillars – diagnostics, therapeutics, vaccines, and the health systems connector. The diagnostics pillar, co-led by FIND and the Global Fund to Fight AIDS, Tuberculosis, and Malaria, aims to avoid 1.6 billion further infections by scaling up access to diagnostics. The pillar requires US $6 billion in the next year, but US $2 billion is urgently needed to begin deploying tests now. Ultimately, 10,000 healthcare workers will be needed. “The real strategy towards containing the epidemic is through testing, tracing, isolation; and the starting point for that is a very rapid rollout of very large numbers of tests,” said Peter Sands, executive director of the Global Fund. “To underscore the urgency for many lower middle income countries, lockdown is not sustainable. Households don’t have the wherewithal to continue without working, and governments don’t have the ability to compensate for lost income, coupled with the fact that clinical care facilities are extremely limited.” The therapeutics pillar will focus on accelerating the development and deployment of effective treatments. While no drugs have yet been tapped, the pillar aims to provide 250 million courses of treatment to LMICS in the next 12 months. Some US$11.6 billion is needed in the next year, while US $3.8 billion is needed immediately. “Of course, as soon as we have a medicine, the situation at the country level will also be a challenge,” said Duneton. “The access to oxygen, for example, is not the same in all countries.” But “the only way to prevent further transmission [of the virus] and to break that cycle, would be to have an effective and safe vaccine available to people,” said WHO Chief Scientist Soumya Swaminathan. Soumya Swaminathan speaks at the 26 June ACT Accelerator press briefing The vaccines pillar has an ambitious goal of delivering 2 billion doses by the end of 2021. Seven candidates are currently in clinical trials, but none have yet received regulatory approval. So far, the fastest vaccine to move from lab bench to approval for human use was the Ebola vaccine – which took five years to develop. “In general, it takes 8 to 10 years for a vaccine to move from when the research begins to when it gets into people. We want to shorten that timeline as short as possible – 12 months, 18 months maximum,” said Swaminathan. “That would be unprecedented, and can only happen through global collaboration.” The Coalition for Epidemic Preparedness Innovation (CEPI), and Gavi, the Vaccine Alliance, will lead the vaccines pillar alongside WHO, which will provide oversight of regulation, policy and allocation. Some US $18.1 billion is required to safely deliver the vaccine to people in need. Gavi, through an advanced market agreement under its COVAX Facility, aims to pool purchasing power from nations of all income levels to secure low vaccine prices. Some 950 million doses must be procured by self-financing, upper-middle and high income countries, in addition to the 2 billion doses set aside for lower income countries. A final pillar, the health systems connector, aims to strengthen the infrastructure and community networks required to deliver tools to people in need. Led by the World Bank, and the Global Fund, the pillar aims to build lab capacity, train staff to safely manage COVID-19, and to use new tools as they are deployed. Image Credits: Flickr: IAEA Imagebank/Natalia Khurtsidze, PR Manager of the Clinic. Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts This site uses cookies to help give you the best experience on our website. Cookies enable us to collect information that helps us personalise your experience and improve the functionality and performance of our site. By continuing to read our website, we assume you agree to this, otherwise you can adjust your browser settings. Please read our cookie and Privacy Policy. Our Cookies and Privacy Policy Loading Comments... You must be logged in to post a comment.
US Secures Most Of World’s Remdesivir For Next 3 Months; Swine Flu Variant Circulating In China Not A New Virus, Says WHO Experts 02/07/2020 Grace Ren Artist’s rendition of SARS-CoV-2, the virus that causes COVID-19 The United States has secured almost all of Gilead Sciences’ projected production of remdesivir – an antiviral that was shown to reduce hospitalization times for COVID-19 patients- for the next three months. US Health and Human Services (HHS) has secured 100 percent of Gilead’s projected production for July (94,200 treatment courses), 90 percent of production in August (174,900 treatment courses), and 90 percent of production in September (232,800 treatment courses), in addition to an allocation for clinical trials, HHS announced in a press release. But while painted as a win for United States patients, some are worried about what the supply looks like for the rest of the world. Word Health Organization Health Emergencies Executive Director Mike Ryan on Wednesday said the agency was investigating reports on the US’ allocation of remdesivir, and also closely monitoring a strain of swine flu that may have pandemic potential. “We’re aware of the reports in the media around this purchase or procurement of remdesivir stocks, and we’re obviously working through our colleagues and our partners and the access to Covid Tools Accelerator to clarify and verify this this report,” Ryan said in response to a query from the Financial Times regarding the US potentially “hoarding” remdesivir. Swine Flu ‘G4’ Variant Being Monitored Closely A swine flu variant, G4 EA H1N1, that captured headlines on Tuesday for its ‘pandemic potential’ has been monitored by WHO and health authorities since 2011, WHO Health Emergencies Executive Director Mike Ryan said Wednesday, attempting to ease fears that a pandemic flu strain could appear on top of this year’s deadly COVID-19 pandemic. “It’s important I think to reassure people that this is not a new virus. This is a virus that is under surveillance,” said Ryan, in response to a query from Bloomberg News. “We are concerned with any viruses that your potential to infect humans, we will continue with our collaboration centers and the global influenza surveillance and response system to keep this virus under close surveillance.” “It’s not an immediate threat where you’re seeing infections, but it’s something we need to keep our eye on, just the way we did in 2009 with the emergence of the swine flu,” Anthony Fauci, director of the United States National Institute of Allergies and Infectious Diseases (NIAID), told reporters Tuesday. “The WHO has been collaborating on surveillance since 2011. The most recent publication is an [analysis] of that surveillance data over that time,” said Ryan on Wednesday. The virus stirred attention after a paper published Tuesday described G4 EA H1N1 as having “all the essential hallmarks of a candidate pandemic virus.” The paper, Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection, was published in the Proceedings of the National Academy of Sciences (PNAS) journal and authored by a team from the China Agricultural University. The G4 EA H1N1 virus, part of a family of “G4” viruses that can make the jump from pigs to humans, may have characteristics of the H1N1 variant that caused the 2009 pandemic, or the deadlier variant that caused the 1918 Spanish flu, said Fauci. And “of concern is that swine workers show elevated seroprevalence for G4 virus,” the authors wrote. Some 10.4% of workers overall showed antibodies for the G4 virus, indicating they had likely been exposed to the virus at some point. The positivity rate in workers between 18 to 35 years old was almost double that. However, there were no records of active, symptomatic infection. “The likelihood that this particular variant is going to cause a pandemic is low,” Martha Nelson, an evolutionary biologist at the U.S. National Institutes of Health’s Fogarty International Center told Science News. Nelson studies pig influenza viruses in the United States and their spread to humans. But other researchers, including Robert Webster, a retired influenza researcher from St. Jude’s Children’s Research Hospital, say flu can be a “guessing game.” “We just do not know a pandemic is going to occur until the damn thing occurs,” Webster told Science News. Image Credits: NIAID, Flickr: liz west. Fateful International Energy Agency Meeting Could Set Course For Climate Friendly COVID-19 Recovery… Or Not 01/07/2020 Editorial team Wind turbines in Derbyshire, United Kingdom, generate energy. A landmark meeting hosted next week by the International Energy Agency (IEA) will bring together major powers to debate the key actions for a climate-friendly COVID-19 recovery in an online forum open to public viewing. The IEA Clean Energy Transitions Summit will be live-streamed July 9th, and bring together the world’s largest economies and developing countries, who generate 80% of global emissions. The meeting aims to develop plans to ramp up emissions-reducing projects to rapidly create new jobs in the wake of economic devastation wrought by the pandemic. Currently, major powers in attendance such as Germany, China and Indonesia already have recovery plans in the work that claim to center climate-friendly initiatives. In a move counter to the administration’s usual dismissive stance on climate, the United States will also be sending a representative to a high-level virtual summit on a ‘green’ COVID-19 recovery on 9 July. US Secretary of State for Energy, Dan Brouillette, will attend a meeting, according to the Guardian. “What kind of energy choices we make now will determine the decades to come,” IEA Executive Director Fatih Birol told the Guardian in an interview. “This will be critical for energy and climate change.” Emissions have gone down dramatically as travel and trade came to a standstill during COVID-19 induced lockdowns, with clear waters in Venice canals and blue skies over New Delhi for the first time in ages. Emissions of noxious greenhouse gases such as NO2, monitored by the US National Aeronautics and Space Administration and the European Space Agency, have decreased in major cities around the world. But there is increasing worry that economic recovery efforts will cause a catastrophic rebound in emissions if there lacks a concerted effort to center climate-friendly initiatives. Participation of Climate Dismissive Governments Key to Success A global ‘green’ recovery can only succeed if countries dismissive of climate change – such as the United States – also sign on to the recovery plans. “Even if governments do not take climate change as a key priority, they should still implement our sustainable recovery plan just to create jobs and to give economic growth. Renovating buildings, for instance, is a job machine,” Birol told the Guardian. So far the US administration has been silent regarding a ‘climate-friendly’ pandemic recovery economy, even as UN agencies, the European Union, and individual countries like Norway and Germany endorse green recovery plans. The US is set to withdraw from the 2015 Paris Agreement, a landmark deal meant to curb emissions to limit the rise of global temperatures, right before US presidential elections on 4 November, highlighting the importance of getting the major emitter on board for recovery plans now, said Birol. China’s energy minister, Zhang Jianhua, the EU commission’s vice-president, Frans Timmermans, and the UK’s business secretary, Alok Sharma, who is president of the 26th UN Conference of Parties climate talks (now postponed to next year), will be attending. Representatives from Indonesia, India, Brazil, and South Africa will also be in attendance. Image Credits: Flickr: The Roaming Picture Taker. Pfizer COVID-19 Vaccine Shows Promising Early Results; Induces Immune Response In Healthy Volunteers 01/07/2020 Grace Ren Manufacturing COVID-19 vaccine at Pfizer A COVID-19 vaccine candidate under development by pharma giant Pfizer and biotech firm BioNTech showed promise in interim results released Wednesday. The vaccine candidate, BNT162b1, was able to induce the formation of antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, in all participants who received doses between 10ug to 30ug, according to a report posted on the preprint server MedRxiv. The report has not yet been peer-reviewed. Seven days after the last injection, levels of neutralizing antibodies in those who received 10 µg and 30 µg of the vaccine 21 days apart were 1.8 to 2.8 times the level of neutralizing antibodies in recovered COVID-19 patients. “These preliminary data are encouraging in that they provide an initial signal that BNT162b1 targeting the RBD SARS-CoV-2 is able to produce neutralizing antibody responses in humans at or above the levels observed in convalescent sera – and that it does so at relatively low dose levels. We look forward to providing further data updates on BNT162b1,” said Ugur Sahin, M.D., CEO and Co-founder of BioNTech, in a press release. The study placed 45 healthy volunteers between the ages of 18 to 55 into three groups for the initial analysis. Some 24 subjects received two injections of 10 µg and 30 µg, 12 subjects received a single injection of 100 µg, and 9 subjects received 2 doses of placebo control. However, the study did not include results from adults over 65 years of age and pregnant women. Three-quarters of the subjects in the first group experienced acute low-grade fever below 100 degrees Celsius, and some experienced minor to moderate pain at the injection site. More trials must be done in order to test whether the vaccine can lower the likelihood of infection by 50%. But the preliminary results indicate that Phase ⅔ trials may be set to start in late July, as Pfizer Chief Executive Officer Albert Bourla told reporters in May. These trials may enroll up to 30,000 healthy volunteers The Pfizer vaccine is one of 14 candidates currently in human trials. It is based on messenger RNA, a single-stranded construct that carries a blueprint for a protein immune cells can then learn to attack, the same model as the Moderna vaccine candidate. The Moderna vaccine also showed promising early results, inducing neutralizing antibodies in a small group of early volunteers, but further results have yet to be released. Image Credits: Pfizer, Pfizer. World Health Organization Will Send Scoping Mission To China To Investigate COVID-19 Origins 30/06/2020 Editorial team Dr Tedros at a June 2020 press briefing The World Health Organization will be sending a mission to China on 6 July to investigate the origins of SARS-CoV-2, the virus that causes COVID-19, WHO Director-General Dr Tedros Adhanom Ghebreyesus subtly announced at a Monday press briefing. The mission aims to fulfill decisions made in a unanimously passed World Health Assembly resolution in late May, which requested WHO work with World Organisation for Animal Health (OIE), the Food and Agriculture Organization of the United Nations (FAO) and countries to “identify the zoonotic source of the virus and the route of introduction to the human population, including the possible role of intermediate hosts.” “We will send a team next week to China to prepare this and hopefully it will lead to a better understanding of how the virus started and what we can do in the future to prepare for it,” said Dr Tedros on Monday, in response to a query from a Brussel Times journalist following-up on the status of actions outlined in the resolution. Two WHO experts will be sent on the initial scoping mission; an expert in animal health and an epidemiology expert with a background in investigating epidemics in the field, WHO Health Emergencies Executive Director Mike Ryan added on Wednesday. While researchers largely believe that the virus jumped the animal-human barrier at a wet market in Wuhan, China, some have posited that the virus may have escaped from a high level virology lab within miles of the first cluster of confirmed cases. The quiet announcement underlines the political tensions surrounding the investigation of origins of the virus, with WHO caught in an ongoing feud between China and the United States. United States President Donald Trump has repeatedly slammed the World Health Organization for supposedly catering to China’s favor and delaying global responses to the pandemic, despite once praising the WHO and China response before COVID-19 reached US shores. Trump has made WHO’s supposed deference to China the main point of contention for withdrawing US support from the agency, even as the US continues to face an accelerating pandemic at home, reporting the highest numbers of new cases and hospitalizations daily. But WHO has little authority over Member States’ actions, and must balance criticising pandemic responses with retaining access to data and knowledge. The first WHO mission to China was delicately arranged at the end of January, after Chinese authorities locked down the Wuhan, a city of 11 million people, following a spike in cases due to a delayed response in early January. Since largely coming out of lockdown in May, the outbreak in China has been tightly controlled. However, new clusters of cases in Jilin province, Wuhan city, and the capital of Beijing have sparked great unease and second rounds of lockdowns. Swelling Indian National Opposition As Modi Plans To Expand Coal Mining 30/06/2020 Jyoti Pande Lavakare Coal miners in India’s resource-rich Meghalaya State. A government tribunal banned coal mining in the region in 2015. New Delhi, India – Prime Minister Narendra’s Modi’s ambitious plan to use coal to power India’s economic revival after his government’s strict lockdowns flattened the wrong curve, bringing economic growth to a halt even as the infection epidemic curve continued to rise, seems to have run into significant opposition from unexpected quarters. Since the launch of his plan earlier this month, state after Indian state has expressed disagreement with the Centre’s plan to commercially auction coal mines to the private sector, including international players. The latest to join the clamour of opposition by the states of Chhattisgarh, Jharkhand and Maharashtra, where more than half of the 41 mines are located – is the politically powerful chief minister of West Bengal, Mamata Banerjee. Indian environmentalists have also decried a seemingly desperate announcement by the government to auction off 41 Indian coal mines, opening a largely government-controlled sector up to all private investment for the first time ever – and thus greatly accelerating domestic coal production. Coal mining by Eastern Coalfields Ltd., the company that operates national coalfields in Jharkhand and West Bengal states. As of now, two government-owned mines produce over 90 % of India’s coal. Indian coal, known for its high fly ash content– and therefore pollution emissions – currently supplies about 80% of the country’s total coal needs, while the rest is imported. Coal, in turn, powers about 44% of the total energy needs, compared to oil (24%) and biomass (22%) – though the latter is often burned in highly polluting domestic cookstoves emitting climate-changing black carbon particles. Also, hydroelectric power supplies 1.4% of the economy, leaving solar and wind to supply only around 0.8% of the country’s total power needs. When it comes to electricity generation, the picture is just a little bit better. Coal powers 73% of electricity in India, while solar and wind fuel around 8% and hydro around 12% respectively, said Karthik Ganesan, Research Fellow, Council on Energy, Environment and Water. Clean air campaigners had hoped that the glimpse of blue skies, clean water bodies and nature restoring itself in the limbo provided by the lockdown of all growth engines would encourage decision-makers to choose a growth recovery path that had low environmental impact. Health and environmentalist activists had expected the government to look at growth recovery more holistically, which meant including developmental indicators like health, education and quality of life – in the spirit of the recent WHO manifesto for a healthy green recovery, which calls to put a stop to fossil fuel subsidies using taxpayer money. Unfortunately, India seems to be ignoring all of the recent health and climate warming signals – the latest being the swarms of locusts that are invading parts of the country as it focuses on coal to fuel its recovery. Ostensibly, Modi’s rationale is that the move will help make India energy self-sufficient and quickly claw back the robust growth curve that had begun to fall off even before the COVID-19 pandemic struck the country. However, investing heavily in coal also serves some of his key political alliances, some of whom – like the Adani Group – are also planning to export massive new coal reserves from Australia to India. Opposition to Modi’s Move Growing in India Existing, new, and planned coal mines in India (Credit: R. Pearce, T. Prater, S. Evans/Carbon Brief) Despite the pressing economic challenges that India admittedly does face, some leading Indian politicians are beginning to speak out in opposition to the coal mining plans – bringing this sector back into centre stage for the first time since “Coalgate,’ a coal scam that tainted the previous government a decade ago. Jharkhand state has already approached the Supreme Court challenging this auction, followed by Chhattisgarh and Maharashtra writing to the central environment minister Prakash Javadekar objecting to the auction. The latest to join the rising voice of critics is the feisty Chief Minister of West Bengal (and Modi’s bete noire) Mamata Banerjee, known for her blunt statements and ability to stand up to the central government. Last Thursday, Ms Banerjee wrote to Modi on Thursday, asking him to reconsider the decision, saying that “this policy can neither bring foreign direct investments not can it bring technologies or know-how which we are unable to access today,” and noting that global investors are more interested in renewable energy projects rather than coal, which offers low returns. None of the 41 mines coming up for auction are located in her state. Her objection is in principle and adds political weight to the growing opposition. States like Jharkhand, Maharashtra and Chhattisgarh, where more than half the mines coming up for auction are located, have already voiced opposition to this decision, citing huge environmental and social costs: “Riding on coal could spur the economy in the very short term and an extremely high ecological and social cost”, said Niraj Bhatt, Researcher in Environment and Climate Action for the Chennai-based Citizen consumer and civic Action Group (CAG), who works in the coal sector. The long term costs of promoting coal are disastrous, even in the government’s very first Climate Assessment report. The report warns of a four-fold increase in heat wave frequency and a doubling in the length of heat waves in India by 2100. “It is inexplicable why the government is prioritizing coal for fast track revival of the Indian economy since the pandemic”, given the knowledge that’s available, added Bhatt. Many local communities also are opposed to the government’s decision to privatize coal mining, fearing that this will degrade the environment. Most of the 41 coal mines in auction are in pristine forest areas. Even at the village-level, several panchayats (local governance bodies that make the fundamental building blocks of governance) have asked Modi to withdraw this auction. “Nine village panchayats from Hasdeo Arand forest region have written to the Prime-minister asking for withdrawing the auction of five coal blocks in the region for commercial mining as it would impact their livelihood and culture,” said Avinash Kumar Chanchal, a grassroots climate activist who has written on the degradation of the Singrauli coal belt and displacement of local communities. UN Secretary General Also Decries Coal Plans There is no good reason for any country to include coal in their #COVID19 recovery plans. This is the time to invest in energy sources that don’t pollute, generate decent jobs and save money. — António Guterres (@antonioguterres) June 29, 2020 United Nations Secretary-General Antonio Guterres has said there is no reason for any country to include coal in the COVID-19 recovery plans. Instead, investments should be made towards non-polluting energy sources; and opposition to a “black, coal-powered recovery” has grown in India. It isn’t clear whether this diplomatic rap on the knuckles and growing opposition will succeed in stopping the government in its polluting tracks, especially if Modi’s public statements on privatising coal mines – framed in his signature style with the bells and whistles of patriotism and nationalism for “atma-nirbharta” or self-reliance – are anything to go by. Desperate for funds and eager to kickstart a sluggish economy threatening to fall into a recession, the central government seems prepared to roadroll its way through. Its desperation stems from predictions of the most severe recession in the past the four decades – The International Monetary Fund has predicted a global annual downturn of 4.5%, though ratings firm India Ratings has predicted the Indian economy to contract by 5.3% this year. Renewable Energy Offers Untapped Potential Analysts say that the government is gambling on coal mining to generate over a million of jobs, as it is labour-intensive and rural communities are increasingly desperate for jobs following mass reverse migration since the pandemic began. Additionally, there is built-in momentum for coal power development, since it is already well-established and subsidized by the government – whereas renewables are a new game altogether, and energy storage issues still remain unresolved – as some critics claim. Activists and economists counter that government forces have ignored the potential of alternative energy sources at the current juncture: “There is huge potential to generate new jobs in renewable energy. Some analyses have estimated that more than one million jobs can be created by the renewable sector by 2022 if India can achieve its ambitious renewable target of 160GW,” said Chanchal. “The illusion of low cost energy from coal has been debunked globally. Socially, environmentally and economically, coal is very costly. It’s bad economic policy to invest in high cost options when cheaper alternatives exist today,” added Laveesh Bhandari, an economist turned environmental advocate, who works at the intersection of sustainable employment and climate change. “It’s almost as if we’re moving backwards. The whole world is moving away from coal. Several studies in India have shown the adverse effects of pollution caused by coal mining on the health of communities living within coal mining areas, especially on the respiratory system.” Even before pandemic, deaths from air pollution have been a major issue in India. In 2016, household pollution led to over a million deaths in India, according to the WHO’s Global Health Observatory; and in 2012, ambient air pollution claimed 620 000 Indian lives, with a shocking toll of over 20 million disability-adjusted life years (DALY), according to the WHO’s global assessment of exposure and burden of disease. However, now there is also the added factor of COVID-19, in which case chronic heavy exposures to air pollution will also increase vulnerability from the virus as well as mortality, said grassroots environmentalist and writer Rinchin, who goes by one name only and works with adivasis in Chhattisgarh. “Whether the Centre can still go ahead is a legal issue, but it will be bad form to go against the position of state governments. India is a federation, and something like mining that impacts not only the environment, but society itself therefore needs to be overseen, regulated and controlled by the state”, added Bhandari. India’s Ambition – Regional Energy Supplier? Coal mining in India While Modi is framing the coal auction as a move towards greater national self-reliance, the story is in fact more complex. His plan may involve ambitions to become a regional energy-producing power. It also aligns national policy with the commercial interests of close political allies – such as Indian billionaire Gautam Adani, and head of the powerful Adani group. Adani is leading the Carmichael project – a massive mining initiative to export Australian coal to India. Just last year, the Australia’s government gave the go-ahead for the project, the world’s largest open pit mine, overriding stiff opposition from Australian environmentalists. Adani plans to use the Australian coal for a new $2 billion power plant that his company is building in India, which will also produce electricity for sale in neighboring Bangladesh. Ever since Modi was the chief minister of the western state of Gujarat – Adani’s birthplace and home region – Adani and Modi were known to have close links. “The story of Adani and its Australian project illustrates why the world keeps burning coal despite its profound danger — and despite falling prices for options like natural gas, wind and solar,” the New York Times said last year. In fact, India’s coal ambitions under Modi will not just undermine existing efforts to limit climate change and worsen air and water pollution within the country, they are also likely to compromise the entire region, setting an undesirable example of fossil fuel dependency in neighbouring countries. Little Matter of Coal Gasification Air pollution in Delhi, India Then, there is that little matter of Modi’s plans for coal gasification – a technology that could further reduce India’s dependence on imports, but at an even higher level of carbon emissions – as well as potential water contamination from coal pollutants. The government’s current plan is to promote “syngas” -a substitute for imported liquified natural gas produced by coal gasification – to produce urea in fertilizer. This will not only help reduce liquified natural gas (LNG) imports but also urea imports, leading to a lower import bill and greater self-reliance. According to the Ministry of Chemicals and Fertilisers, urea is currently produced using pooled natural gas, which consists of both domestic natural gas and imported LNG. The usage of locally available coal for making fertilisers would help reduce the import of LNG, the Ministry has said. “The big question is when we have cleaner, cheaper, and sustainable renewable energy sources why do we want to invest in dirty and polluting technologies and energy sources? India is already facing a climate crisis,” said Chanchal. While natural gas is considered a lower climate emitter than coal, syngas is just the opposite. A study by Duke University found that syngas produced by coal gasification emits seven times more greenhouse gases than natural gas, making it a huge contributor to climate change. “It contaminates both surface water and groundwater, and also emits greenhouse gases. If renewable energy is available and becoming cheaper day by day, then why does the government want to start commercial mining to create coal based energy.” “Right now, the government is speaking like a climate leader but acting like a climate laggard by betting high on coal and promoting it,” added Bhatt. Mining Could Also Increase Dangerous Human-Wildlife Conflicts Dog sleeps on a bed of coal in Asansol, India Along with the climate and air pollution risks, activists have also warned that expanding mining operations in the areas up for auction could trigger increased human-wildlife conflict. “Among the 41 coal mines up for auction, most are situated in the dense forest of central India,” said Chanchal. “These forests are home to large populations of elephants and other wildlife. Some proposed coal blocks are also near tiger reserves, like in Maharashtra. “Along with vast forest destruction, coal mines will also increase the human-wildlife conflict. The implications are countless from the displacement of adivasis, to the violation of the Forest Rights Act, to public health,” said Chanchal, who has also written The Singrauli Files about the degradation of that region. “We have already seen how coal mines destroyed the rich biodiversity of places like Singrauli, Korba, and in other coal belts where thousands of adivasi and local communities were displaced, their forests, livelihood and human rights violated. They are already living with serious health crises,” he added. In a parallel move, Modi’s Ministry of Environment and Forestry also has launched an initiative to dilute existing environmental impact assessment norms for the creation of industries in pristine areas, including, but not limited to coal – a move that has been staunchly opposed by environmentalists – but action on that has been postponed by the courts until August. Modi Still Likely to Face Bureaucratic Challenges India’s Prime Minister Narendra Modi Despite the burgeoning opposition, Modi remains determined and eager to develop the private coal sector. Against the wave of new criticism he has remained silent – a typical tactic of response. However, India’s federal structure of governance may still slow down the realization of his vision considerably – giving environmentalist valuable time to mount a more organized local and global opposition. In the Indian governance model, the central government is expected to execute policy in consultation with state governments on a consensus model. More importantly, if the land is pristine forest land, as in this case, local self-governance laws and the FRA will make it challenging for it to move ahead with coal block allocation in such areas, which may still stave off this path to a quicker, but blacker, revival. “Land is a state subject, the Centre cannot go ahead without support from the states,” said Bhatt. “The implementation of the Forest Rights Act is also very crucial in these regions. The government which is promoting ‘atma-nirbhar Bharat’ should consider these concerns of local communities and take appropriate action to strengthen the self-governance of the gram sabha,” adds Chanchal. Image Credits: Environmental Change and Security Program, Flickr: Partha Sarathi Sahana, R. Pearce, T. Prater, S. Evans/Carbon Brief, Environmental Change and Security Program, Wikimedia Commons: Prami.ap90, Flickr: Partha Sarathi Sahana, Mike Bloomberg. World Surpasses 500,000 COVID-19 Deaths; Medicines Access Experts Challenge US $2340 Per Remdesivir Treatment Course Price Set By Gilead For Developed Countries 29/06/2020 Grace Ren Vial of remdesivir A six-vial five-day course of remdesivir – a promising COVID-19 treatment – will be priced at US $2340, or $390 per vial for developed countries, Gilead Sciences Chief Executive Officer Daniel O’Day wrote in an open letter on Monday. “Earlier hospital discharge [thanks to treatment by remdesivir] would result in hospital savings of approximately $12,000 per patient,” wrote O’Day. “We have decided to price remdesivir well below this value.” But the price is still high compared to the cost of manufacturing, according to medicines access experts, who say that remdesivir could be produced for below a dollar a day. Private insurers in the United States will pay US $3,120 for a five-day course, or $520 per vial. Out-of-pocket payments will be determined by individuals’ coverage plans. In 127 developing countries, Gilead has allowed generics companies to manufacture the drug, pricing a five-day course at about US $600. Cost of production for the drug can be as low as US $0.93 per day, according to a paper by Dr Andrew Hill, a senior visiting research fellow at the University of Liverpool, and his colleagues. “Gilead will turn a nice profit with its set price. Especially considering that the company has benefitted from significant government financing for the development of the drug; which apparently has not been discounted,” Ellen t’Hoen, director of Medicines, Law and Policy, told Health Policy Watch. electron microscope photo of SARS-CoV-2, the virus that causes COVID-19 “Based on publicly available data, it has been estimated that taxpayers have contributed at least $70.5 million to develop this drug,” Jessica Burry, a pharmacist at Médecins Sans Frontières Access Campaign, said to Health Policy Watch. “Additionally, contributions were made by various health organisations, including MSF, which supported clinical trials with this drug for Ebola in 2019. Patients themselves have also contributed by their participation in the trials. “Public funding and resources have contributed to the drug’s further development for COVID-19, and taxpayers will now end up essentially “paying twice” to access this treatment,” added Burry. The company could turn a US $2.3 billion profit on the “blockbuster” drug this year alone, according to a blog by Ellen t’Hoen. “This does put pharma’s lofty promises of not profiteering during the pandemic into perspective. I hope governments begin to realise that the important investments they make for the development of drugs and vaccines to respond to COVID-19 need to come with strings attached to ensure fair pricing and global access,” she said. COVID-19 Cases Surge Past 10,000,000, Deaths Reach Half A Million Meanwhile, the World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus warned on Monday that “the worst was yet to come.” Dr Tedros spoke at a press conference just as the number of deaths from COVID-19 topped half a million, and cumulative cases surged past 10,000,000. The US and Brazil continue to report around 40,000 new cases day. In the state of Texas, which saw one of the fastest rising daily case counts after reopening, hospitals in the capital city of Houston are nearing ICU capacity. Even as Vice President Mike Pence lauded the state’s reopening at a press briefing Monday, Texas Governor Greg Abbot warned that the epidemic had taken a “very swift and very dangerous turn.” Abbot shut down bars and clubs again across the state in an attempt to limit the fast-spreading virus. Remdesivir Pricing Announcement Comes On Heels Of EMA Conditional Marketing Authorization Endorsement Remdesivir, a failed Ebola antiviral, is one of the frontrunner drugs for treating COVID-19. It was shown to significantly reduce the length of hospital stay from an average of 11 days to an average of 15 days in a recent trial funded by the US National Institute of Allergies and Infectious Diseases (NIAID). However, the NIAID trial results were based on a 10-day treatment course, rather than the 5-day course that Gilead has currently priced. And studies have so far not reported any effects in reducing mortality. Still, the European Medicines Agency recently renewed their endorsement of the drug, recommending the agency give remdesivir conditional marketing authorization – a stamp of approval that many European Union countries use as guidance for approving drugs for diseases with few cures. Remdesivir is currently approved for use in Japan for COVID-19 patients. The United States Food and Drug Administration has approved the treatment for ’emergency’ use, just two days after the NIAID trial results were announced. The announcement comes just as Gilead’s promise to donate remdesivir until the end of June 2020 hits its deadline. US Health and Human Services Secretary Alex Azar announced Monday that the government had secured another half a million treatment courses of remdesivir for U.S. hospitals through September, according to an interview with “Good Morning America.” Health and Human Services will be paying the US $390 per vial price, and be responsible for allocating Gilead’s supply of remdesivir, according to O’Day’s letter. But some middle income countries that are hoping to secure their own supply of remdesivir may be out of luck, according to Burry. “Gilead has entered into license agreements with several generic companies in India, Pakistan and Egypt. The license, however, excludes nearly half of the world’s population, including most South American countries and a number of middle-income countries, such as Brazil, Russia and China,” said Burry. “Since the corporation has barely been able to supply enough quantities of this drug even to the US, it is highly unlikely that it will be able to meet the demands of all the other countries that have not been included in this license.” Brazil Signs Contract To Produce AstraZeneca & Oxford COVID-19 Vaccine Candidate; China Approves CanSino Vaccine Candidate For Military Use In a parallel development, Brazil on Saturday signed a contract with AstraZeneca and Oxford to manufacture an experimental COVID-19 vaccine candidate. Meanwhile, China approved the CanSino COVID-19 vaccine candidate for military use on Thursday. Local vaccine manufacturer Fiocruz will be producing up to 100 million doses of the vaccine overall, Brazilian authorities announced at a press briefing. The country will pay $127 million to receive material to produce 30.4 million doses in two batches in December and January, with the rest to come later. China’s Central Military Commission approved the CanSino vaccine for use by the military for a period of one year beginning 25 June 2020, according to a CanSino filing. The Academy of Military Sciences had jointly developed the vaccine candidate with CanSino. Results from a small, non-randomized trial released in May found that about 75% of people who received high doses of the CanSino vaccine candidate developed antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, after 28 days. However, the developers highlight that large, randomized control trials must be done in order to determine if the vaccine truly protects against infection by the virus. And other researchers pointed to old concerns with the Ad5 vector used in the CanSino vaccine. Previous Ad5-vectored vaccine candidates for HIV were dropped after early trials showed the experimental vaccine inadvertently increased the risk of HIV infection. This story was updated 30 June 2020. Image Credits: European Medicines Agency, NIAID, World Health Organization, NIAID. Gender-Based Violence – The “Shadow Pandemic” Of COVID-19 26/06/2020 Paul Adepoju While a face mask could provide some protection against COVID-19, the lives of many women in Africa, and elsewhere, are at the mercy of their abusers. (Photo Credit: Paul Adepoju) Ibadan, Nigeria – Twenty-two year-old Uwaila Vera Omozuwa, freshly admitted to university, had retreated to study in a church in the city of Benin, Nigeria during lockdown, when she was raped and killed on May 30. The following day, 18-year-old Barakat Bello was reportedly raped and killed in Oyo state. 29-year-old Azeezat Shomuyiwa and 21-year-old Grace Oshiagwu also suffered similar fates just days and few streets apart. In late March 2020, a video from Ghana surfaced on social media showing a boyfriend assaulting his girlfriend. As the COVID-19 pandemic continues to expand globally, African countries as well as other nations worldwide are also dealing with another related pandemic – that of gender-based violence. The stress triggered by COVID-19 lockdowns and economic uncertainty is exacerbating violent assaults, according to experts speaking at a panel last week hosted by the WHO Regional Office for Africa. Effectively, the pandemic has forced many women who are in abusive relationships to remain shut up at home with their abusers, further escalating their risks, they said. Social media responses condemning the gruesome murder and rape of Vera Uwaila Omozuwa. (Photo Credit: Youth Alive Foundation ) A “Shadow Pandemic” Gender-based violence is a “shadow pandemic” to COVID-19 said UN Women’s Executive Director, Phumzile Mlambo-Ngcuka. She noted that in Africa as well as elsewhere in the world, domestic violence hotlines and shelters are reporting rising calls for help. “Confinement is fostering the tension and strain created by security, health, and money worries. And it is increasing isolation for women with violent partners, separating them from the people and resources that can best help them,” Mlambo-Ngcuka said in a statement on violence against women and girls. “It’s a perfect storm for controlling, violent behaviour behind closed doors. And in parallel, as health systems are stretching to breaking point, domestic violence shelters are also reaching capacity, a service deficit made worse when centres are repurposed for additional COVID-response.” Africa has struggled with social attitudes sanctioning violent attacks on women, well before the pandemic began. For instance, in 2017, researchers at the University of Ghana reported that men who were in consensual unions or customary marriages remained in favour of wife beating. Police attitudes are often lax as well. Following Uwaila’s rape and murder in Benin, Nigeria, for instance, the local police initially demanded a “mobilization money” from the family to open an investigation, according to the victim’s sister, who finally led a protest to the Edo State police headquarters to trigger action – which she videotaped on Instagram. Now, in the period of COVID-19, for every 3 months lockdowns are imposed or continue, an additional 15 million extra cases of gender-based violence could be recorded worldwide, states a new report, COVID-19: A Gender Lens, by the UN Population Fund (UNFPA). And six months of lockdown could result in additional 31 million cases of gender-based violence in the world. Photo Credit: UN Women While the most extreme outcome, gender-based violence is not the only way women are suffering from lockdown restrictions, noted Dr. Natalia Kanem, UNFPA Executive Director while unveiling a new analysis by UNFPA and partners. “Millions more women and girls now risk losing the ability to plan their families and protect their bodies and their health,” she said, noting that women often cannot get to health services for basic care. “Women’s reproductive health and rights must be safeguarded at all costs. The services must continue; the supplies must be delivered; and the vulnerable must be protected and supported.” Fighting the Shadow Pandemic In Africa, political leaders have generally been reluctant to make themselves the face of campaigns against gender-based violence, the panel participants observed, recommending that Africa’s political leaders need to start speaking up now. “African leaders need to declare this situation as another pandemic and appeal to people, men, society, and those who set norms. African leaders need to speak up and recognise this is happening,” said Dr Matshidiso Moeti, WHO African Regional Director while speaking on the panel. Governments also need to make gender-violence prevention initiatives integral to economic and healthcare programmes dealing with COVID-19, she said. Matshidiso Moeti Specifically, she mentioned that police officers and health workers in African countries need to be made aware of the roles they are supposed to play in prevention of gender-based violence. For countries that are still in the dark over what to do, she noted that the government can work with men and women groups to improve the level of public education, provision of call numbers to report cases of abuse, and establishment of shelters to provide help and services to victims. “These can be part of the socio-economic response to the pandemic,” Moeti added. While most African countries now have legislation against gender-based violence, political leadership is still missing, agreed Winnie Byanyima, Executive Director of the Joint United Nations Programme on HIV/AIDS (UNAIDS). “I so rarely hear a male African leader speaking and leading on this issue. Most African leaders leave it to others, yet it is a pandemic – a silent one too,” Byanyima said. For Africa to advance in tackling gender-based violence, African leaders must be saddled with the responsibility of providing political leadership, she said. One leader that has spoken up recently was South African President Cyril Ramaphosa, a political powerful voice, as he is also the head of the African Union. Speaking to the media last week, he blamed the reopening of liquor stores as lockdown measures eased for a spate of attacks on women in that country. Those included pregnant, Tshegofatso Pule who was found hanging from a tree, Naledi Phangindawo, who was stabbed, and Sanele Mfaba whose body was later found in a Soweto township. South African campaigners note that in fact violence against women shot up from the moment the lockdowns began. The police force’s gender-based violence hotline received 2,300 calls in the first five days – nearly three times the rate prior to lockdown. Even so, Ramaphosa’s remarks were significant as this represented one of the few instances when an African Head of State has spoken out forcefully on the issue. Community-based Prevention and Education Are Key While some actions are being taken to improve Africa’s response to gender-based violence including building police and judiciary systems that understand their roles and can prosecute cases of gender-based violence, more needs to be done about awareness-raising and education that can prevent crimes from ever occurring, stressed Byanyima. “In my view, we are weakest on prevention. You need aggressive campaigns discouraging violent behaviors of boys and men, especially the way they see their masculinity and how they exercise it. That discouragement still needs to happen,” Byanyima said. Presently, this duty is largely left to civil societies and women organisations, but Byanyima noted that it is the business of the government to invest in continual campaigning in communities to change how relationships can be managed without violence. Winnie Byanyima “This is about men’s behavior – the way men are raised and see themselves as men. Tackling toxic masculinity is something that is not well invested in,” she said. Another necessary action to tackle the silent pandemic is to empower girls and women in African societies. Citing data from HIV, the UNAIDS Executive Director noted that an African girl’s vulnerability to HIV, sexual violence, unintended pregnancy and early marriage reduce by up to 50% if she is able to complete high school. But while African leaders have ratified universal basic education requiring every child to get at least primary education, two-thirds of children in Africa do not have access to secondary education. “The time for secondary education has come. We fought for universal primary education in Beijing and within ten years we have achieved it. Now we need to draw the line and say every government worth its name must put its kids, boys and girls, through high school. Not only for the knowledge economy but also for the safety and empowerment of girls and fighting gender-based violence,” Byanyima said. Story of Success: Experts Laud Rwanda’s One Stop Center For Sexual Violence Bineta Diop, African Union’s Special Envoy on Women Peace & Security, recommended African governments adopting Rwanda’s one-stop center for sexual violence. Located within the Kacyiru Police Hospital, the Isange One Stop Centre, the Isange One Stop Center has become a hub for gender-based violence survivors. At the center, survivors can access all the required services in one place and for free. The center is operated by the country’s Gender and Family Promotion, of Health, and Justice ministries in addition to the Rwanda National Police. Bineta Diop The initiative that started in 2009 as a pilot has since been expanded across the country. Rwanda now has a One Stop Centre in every district. Every day, up to 12 survivors are received at the center. “28% are survivors of intimate partner violence and 78 percent are survivors of sexual violence. Of the 78% of survivors who have been sexually assaulted, 16% are younger than 5 years,” said Daniel Nyamwasa, Commissioner of Police and Chief Infectologist Consultant at the hospital. Diop also encouraged African governments to acquire DNA testing capabilities to provide evidence that could be used to prosecute cases of rape and other gender-based violence against women and girls. Enlisting More Women in Police and Judiciary Another solution is the enlistment of more women in the police and judiciary systems across the continent which Diop said will encourage more women to approach the legal system to file complaints. She also called for the engagement of Africa’s traditional leaders. “If you want to break the patriarchal system, you have to engage the traditional system,” Diop said. However, as the number of confirmed cases of COVID-19 in Africa is increasing, African governments are also focusing on how to quickly and safely reopen their economies to minimize the impact of the pandemic. This current reality threatens the materialization of recommendations giving more attention to combating gender-based violence. But Ramaphosa, for one, has said this does not have to be the case. In his comments last week, he stressed that action can and should be taken to combat violence, despite the numerous familiar and peculiar challenges that countries across the continent are facing: “For public faith in the criminal justice system to be maintained, gender-based violence needs to be treated with the urgency it deserves by our communities working together with our police.” Cyril Ramaphosa, President of South Africa Image Credits: Paul Adepoju, Twitter: Youth Alive Foundation, UN Women. Massive Mobilization Of US $31.3 Billion Required For COVID-19 Diagnostics, Drugs & Vaccines Accelerator 26/06/2020 Grace Ren Central Laboratory at the Academician Nikoloz Kipshidze University Clinic, Tbilisi, Georgia, receives laboratory equipment for COVID-19 diagnosis. The World Health Organization aims to raise a whopping US $31.3 billion to fund the ambitious goals of the Access to COVID-19 Tools (ACT) Accelerator; a multi-stakeholder initiative that aims to develop and deploy diagnostics, drugs, and vaccines to control the virus. But so far, only $US 3.4 billion has been pledged towards the initial goals. And US $13.7 billion is ‘urgently needed’ in order to cover immediate needs, according to an investment case released by WHO on Friday. “Though these numbers sound big, they are not. If we spend billions now, we will avoid spending trillions later. The time to act is now, and the way to act is together,” said Gavi Board Chair Ngozi Okonjo-Iweala. The funding will go toward: Scaling up development and delivery of 500 million diagnostic tests to low- and middle-income countries (LMICS) by mid-2021 Delivering 245 million courses of treatments to LMICs by mid-2021, Delivering 2 billion vaccine doses, of which 50% will go to LMICs by the end of 2021. “It’s clear that because all people are at risk of COVID-19, all people should have access to all the tools to prevent, detect and treated, not only those who can afford to pay for them,” said World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus at a Friday press briefing. “We have made the principle of equitable access a simple thing to say, but a complicated thing to implement.” Dr Tedros at the 26 June press briefing More than 9 million people have been infected, and nearly half a million have so far lost their lives to the virus. The investment required in the Accelerator is less than a tenth of the loss the global economy is facing every month due to the pandemic, according to International Monetary Fund estimates. “The cost of inaction now is quite important to take into consideration,” said Philippe Duneton, executive director of UNITAID, working with the Wellcome Trust on the therapeutics pillar of the project. A good portion of the immediate investments will go towards preparing markets to absorb new COVID-19 technologies, setting up demand, manufacturing, and country capacity to roll out any new diagnostics, vaccines, or drugs. Four Investment Pillars Require Urgent Funding The ACT Accelerator operates under four main pillars – diagnostics, therapeutics, vaccines, and the health systems connector. The diagnostics pillar, co-led by FIND and the Global Fund to Fight AIDS, Tuberculosis, and Malaria, aims to avoid 1.6 billion further infections by scaling up access to diagnostics. The pillar requires US $6 billion in the next year, but US $2 billion is urgently needed to begin deploying tests now. Ultimately, 10,000 healthcare workers will be needed. “The real strategy towards containing the epidemic is through testing, tracing, isolation; and the starting point for that is a very rapid rollout of very large numbers of tests,” said Peter Sands, executive director of the Global Fund. “To underscore the urgency for many lower middle income countries, lockdown is not sustainable. Households don’t have the wherewithal to continue without working, and governments don’t have the ability to compensate for lost income, coupled with the fact that clinical care facilities are extremely limited.” The therapeutics pillar will focus on accelerating the development and deployment of effective treatments. While no drugs have yet been tapped, the pillar aims to provide 250 million courses of treatment to LMICS in the next 12 months. Some US$11.6 billion is needed in the next year, while US $3.8 billion is needed immediately. “Of course, as soon as we have a medicine, the situation at the country level will also be a challenge,” said Duneton. “The access to oxygen, for example, is not the same in all countries.” But “the only way to prevent further transmission [of the virus] and to break that cycle, would be to have an effective and safe vaccine available to people,” said WHO Chief Scientist Soumya Swaminathan. Soumya Swaminathan speaks at the 26 June ACT Accelerator press briefing The vaccines pillar has an ambitious goal of delivering 2 billion doses by the end of 2021. Seven candidates are currently in clinical trials, but none have yet received regulatory approval. So far, the fastest vaccine to move from lab bench to approval for human use was the Ebola vaccine – which took five years to develop. “In general, it takes 8 to 10 years for a vaccine to move from when the research begins to when it gets into people. We want to shorten that timeline as short as possible – 12 months, 18 months maximum,” said Swaminathan. “That would be unprecedented, and can only happen through global collaboration.” The Coalition for Epidemic Preparedness Innovation (CEPI), and Gavi, the Vaccine Alliance, will lead the vaccines pillar alongside WHO, which will provide oversight of regulation, policy and allocation. Some US $18.1 billion is required to safely deliver the vaccine to people in need. Gavi, through an advanced market agreement under its COVAX Facility, aims to pool purchasing power from nations of all income levels to secure low vaccine prices. Some 950 million doses must be procured by self-financing, upper-middle and high income countries, in addition to the 2 billion doses set aside for lower income countries. A final pillar, the health systems connector, aims to strengthen the infrastructure and community networks required to deliver tools to people in need. Led by the World Bank, and the Global Fund, the pillar aims to build lab capacity, train staff to safely manage COVID-19, and to use new tools as they are deployed. Image Credits: Flickr: IAEA Imagebank/Natalia Khurtsidze, PR Manager of the Clinic. Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts This site uses cookies to help give you the best experience on our website. Cookies enable us to collect information that helps us personalise your experience and improve the functionality and performance of our site. By continuing to read our website, we assume you agree to this, otherwise you can adjust your browser settings. Please read our cookie and Privacy Policy. Our Cookies and Privacy Policy Loading Comments... You must be logged in to post a comment.
Fateful International Energy Agency Meeting Could Set Course For Climate Friendly COVID-19 Recovery… Or Not 01/07/2020 Editorial team Wind turbines in Derbyshire, United Kingdom, generate energy. A landmark meeting hosted next week by the International Energy Agency (IEA) will bring together major powers to debate the key actions for a climate-friendly COVID-19 recovery in an online forum open to public viewing. The IEA Clean Energy Transitions Summit will be live-streamed July 9th, and bring together the world’s largest economies and developing countries, who generate 80% of global emissions. The meeting aims to develop plans to ramp up emissions-reducing projects to rapidly create new jobs in the wake of economic devastation wrought by the pandemic. Currently, major powers in attendance such as Germany, China and Indonesia already have recovery plans in the work that claim to center climate-friendly initiatives. In a move counter to the administration’s usual dismissive stance on climate, the United States will also be sending a representative to a high-level virtual summit on a ‘green’ COVID-19 recovery on 9 July. US Secretary of State for Energy, Dan Brouillette, will attend a meeting, according to the Guardian. “What kind of energy choices we make now will determine the decades to come,” IEA Executive Director Fatih Birol told the Guardian in an interview. “This will be critical for energy and climate change.” Emissions have gone down dramatically as travel and trade came to a standstill during COVID-19 induced lockdowns, with clear waters in Venice canals and blue skies over New Delhi for the first time in ages. Emissions of noxious greenhouse gases such as NO2, monitored by the US National Aeronautics and Space Administration and the European Space Agency, have decreased in major cities around the world. But there is increasing worry that economic recovery efforts will cause a catastrophic rebound in emissions if there lacks a concerted effort to center climate-friendly initiatives. Participation of Climate Dismissive Governments Key to Success A global ‘green’ recovery can only succeed if countries dismissive of climate change – such as the United States – also sign on to the recovery plans. “Even if governments do not take climate change as a key priority, they should still implement our sustainable recovery plan just to create jobs and to give economic growth. Renovating buildings, for instance, is a job machine,” Birol told the Guardian. So far the US administration has been silent regarding a ‘climate-friendly’ pandemic recovery economy, even as UN agencies, the European Union, and individual countries like Norway and Germany endorse green recovery plans. The US is set to withdraw from the 2015 Paris Agreement, a landmark deal meant to curb emissions to limit the rise of global temperatures, right before US presidential elections on 4 November, highlighting the importance of getting the major emitter on board for recovery plans now, said Birol. China’s energy minister, Zhang Jianhua, the EU commission’s vice-president, Frans Timmermans, and the UK’s business secretary, Alok Sharma, who is president of the 26th UN Conference of Parties climate talks (now postponed to next year), will be attending. Representatives from Indonesia, India, Brazil, and South Africa will also be in attendance. Image Credits: Flickr: The Roaming Picture Taker. Pfizer COVID-19 Vaccine Shows Promising Early Results; Induces Immune Response In Healthy Volunteers 01/07/2020 Grace Ren Manufacturing COVID-19 vaccine at Pfizer A COVID-19 vaccine candidate under development by pharma giant Pfizer and biotech firm BioNTech showed promise in interim results released Wednesday. The vaccine candidate, BNT162b1, was able to induce the formation of antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, in all participants who received doses between 10ug to 30ug, according to a report posted on the preprint server MedRxiv. The report has not yet been peer-reviewed. Seven days after the last injection, levels of neutralizing antibodies in those who received 10 µg and 30 µg of the vaccine 21 days apart were 1.8 to 2.8 times the level of neutralizing antibodies in recovered COVID-19 patients. “These preliminary data are encouraging in that they provide an initial signal that BNT162b1 targeting the RBD SARS-CoV-2 is able to produce neutralizing antibody responses in humans at or above the levels observed in convalescent sera – and that it does so at relatively low dose levels. We look forward to providing further data updates on BNT162b1,” said Ugur Sahin, M.D., CEO and Co-founder of BioNTech, in a press release. The study placed 45 healthy volunteers between the ages of 18 to 55 into three groups for the initial analysis. Some 24 subjects received two injections of 10 µg and 30 µg, 12 subjects received a single injection of 100 µg, and 9 subjects received 2 doses of placebo control. However, the study did not include results from adults over 65 years of age and pregnant women. Three-quarters of the subjects in the first group experienced acute low-grade fever below 100 degrees Celsius, and some experienced minor to moderate pain at the injection site. More trials must be done in order to test whether the vaccine can lower the likelihood of infection by 50%. But the preliminary results indicate that Phase ⅔ trials may be set to start in late July, as Pfizer Chief Executive Officer Albert Bourla told reporters in May. These trials may enroll up to 30,000 healthy volunteers The Pfizer vaccine is one of 14 candidates currently in human trials. It is based on messenger RNA, a single-stranded construct that carries a blueprint for a protein immune cells can then learn to attack, the same model as the Moderna vaccine candidate. The Moderna vaccine also showed promising early results, inducing neutralizing antibodies in a small group of early volunteers, but further results have yet to be released. Image Credits: Pfizer, Pfizer. World Health Organization Will Send Scoping Mission To China To Investigate COVID-19 Origins 30/06/2020 Editorial team Dr Tedros at a June 2020 press briefing The World Health Organization will be sending a mission to China on 6 July to investigate the origins of SARS-CoV-2, the virus that causes COVID-19, WHO Director-General Dr Tedros Adhanom Ghebreyesus subtly announced at a Monday press briefing. The mission aims to fulfill decisions made in a unanimously passed World Health Assembly resolution in late May, which requested WHO work with World Organisation for Animal Health (OIE), the Food and Agriculture Organization of the United Nations (FAO) and countries to “identify the zoonotic source of the virus and the route of introduction to the human population, including the possible role of intermediate hosts.” “We will send a team next week to China to prepare this and hopefully it will lead to a better understanding of how the virus started and what we can do in the future to prepare for it,” said Dr Tedros on Monday, in response to a query from a Brussel Times journalist following-up on the status of actions outlined in the resolution. Two WHO experts will be sent on the initial scoping mission; an expert in animal health and an epidemiology expert with a background in investigating epidemics in the field, WHO Health Emergencies Executive Director Mike Ryan added on Wednesday. While researchers largely believe that the virus jumped the animal-human barrier at a wet market in Wuhan, China, some have posited that the virus may have escaped from a high level virology lab within miles of the first cluster of confirmed cases. The quiet announcement underlines the political tensions surrounding the investigation of origins of the virus, with WHO caught in an ongoing feud between China and the United States. United States President Donald Trump has repeatedly slammed the World Health Organization for supposedly catering to China’s favor and delaying global responses to the pandemic, despite once praising the WHO and China response before COVID-19 reached US shores. Trump has made WHO’s supposed deference to China the main point of contention for withdrawing US support from the agency, even as the US continues to face an accelerating pandemic at home, reporting the highest numbers of new cases and hospitalizations daily. But WHO has little authority over Member States’ actions, and must balance criticising pandemic responses with retaining access to data and knowledge. The first WHO mission to China was delicately arranged at the end of January, after Chinese authorities locked down the Wuhan, a city of 11 million people, following a spike in cases due to a delayed response in early January. Since largely coming out of lockdown in May, the outbreak in China has been tightly controlled. However, new clusters of cases in Jilin province, Wuhan city, and the capital of Beijing have sparked great unease and second rounds of lockdowns. Swelling Indian National Opposition As Modi Plans To Expand Coal Mining 30/06/2020 Jyoti Pande Lavakare Coal miners in India’s resource-rich Meghalaya State. A government tribunal banned coal mining in the region in 2015. New Delhi, India – Prime Minister Narendra’s Modi’s ambitious plan to use coal to power India’s economic revival after his government’s strict lockdowns flattened the wrong curve, bringing economic growth to a halt even as the infection epidemic curve continued to rise, seems to have run into significant opposition from unexpected quarters. Since the launch of his plan earlier this month, state after Indian state has expressed disagreement with the Centre’s plan to commercially auction coal mines to the private sector, including international players. The latest to join the clamour of opposition by the states of Chhattisgarh, Jharkhand and Maharashtra, where more than half of the 41 mines are located – is the politically powerful chief minister of West Bengal, Mamata Banerjee. Indian environmentalists have also decried a seemingly desperate announcement by the government to auction off 41 Indian coal mines, opening a largely government-controlled sector up to all private investment for the first time ever – and thus greatly accelerating domestic coal production. Coal mining by Eastern Coalfields Ltd., the company that operates national coalfields in Jharkhand and West Bengal states. As of now, two government-owned mines produce over 90 % of India’s coal. Indian coal, known for its high fly ash content– and therefore pollution emissions – currently supplies about 80% of the country’s total coal needs, while the rest is imported. Coal, in turn, powers about 44% of the total energy needs, compared to oil (24%) and biomass (22%) – though the latter is often burned in highly polluting domestic cookstoves emitting climate-changing black carbon particles. Also, hydroelectric power supplies 1.4% of the economy, leaving solar and wind to supply only around 0.8% of the country’s total power needs. When it comes to electricity generation, the picture is just a little bit better. Coal powers 73% of electricity in India, while solar and wind fuel around 8% and hydro around 12% respectively, said Karthik Ganesan, Research Fellow, Council on Energy, Environment and Water. Clean air campaigners had hoped that the glimpse of blue skies, clean water bodies and nature restoring itself in the limbo provided by the lockdown of all growth engines would encourage decision-makers to choose a growth recovery path that had low environmental impact. Health and environmentalist activists had expected the government to look at growth recovery more holistically, which meant including developmental indicators like health, education and quality of life – in the spirit of the recent WHO manifesto for a healthy green recovery, which calls to put a stop to fossil fuel subsidies using taxpayer money. Unfortunately, India seems to be ignoring all of the recent health and climate warming signals – the latest being the swarms of locusts that are invading parts of the country as it focuses on coal to fuel its recovery. Ostensibly, Modi’s rationale is that the move will help make India energy self-sufficient and quickly claw back the robust growth curve that had begun to fall off even before the COVID-19 pandemic struck the country. However, investing heavily in coal also serves some of his key political alliances, some of whom – like the Adani Group – are also planning to export massive new coal reserves from Australia to India. Opposition to Modi’s Move Growing in India Existing, new, and planned coal mines in India (Credit: R. Pearce, T. Prater, S. Evans/Carbon Brief) Despite the pressing economic challenges that India admittedly does face, some leading Indian politicians are beginning to speak out in opposition to the coal mining plans – bringing this sector back into centre stage for the first time since “Coalgate,’ a coal scam that tainted the previous government a decade ago. Jharkhand state has already approached the Supreme Court challenging this auction, followed by Chhattisgarh and Maharashtra writing to the central environment minister Prakash Javadekar objecting to the auction. The latest to join the rising voice of critics is the feisty Chief Minister of West Bengal (and Modi’s bete noire) Mamata Banerjee, known for her blunt statements and ability to stand up to the central government. Last Thursday, Ms Banerjee wrote to Modi on Thursday, asking him to reconsider the decision, saying that “this policy can neither bring foreign direct investments not can it bring technologies or know-how which we are unable to access today,” and noting that global investors are more interested in renewable energy projects rather than coal, which offers low returns. None of the 41 mines coming up for auction are located in her state. Her objection is in principle and adds political weight to the growing opposition. States like Jharkhand, Maharashtra and Chhattisgarh, where more than half the mines coming up for auction are located, have already voiced opposition to this decision, citing huge environmental and social costs: “Riding on coal could spur the economy in the very short term and an extremely high ecological and social cost”, said Niraj Bhatt, Researcher in Environment and Climate Action for the Chennai-based Citizen consumer and civic Action Group (CAG), who works in the coal sector. The long term costs of promoting coal are disastrous, even in the government’s very first Climate Assessment report. The report warns of a four-fold increase in heat wave frequency and a doubling in the length of heat waves in India by 2100. “It is inexplicable why the government is prioritizing coal for fast track revival of the Indian economy since the pandemic”, given the knowledge that’s available, added Bhatt. Many local communities also are opposed to the government’s decision to privatize coal mining, fearing that this will degrade the environment. Most of the 41 coal mines in auction are in pristine forest areas. Even at the village-level, several panchayats (local governance bodies that make the fundamental building blocks of governance) have asked Modi to withdraw this auction. “Nine village panchayats from Hasdeo Arand forest region have written to the Prime-minister asking for withdrawing the auction of five coal blocks in the region for commercial mining as it would impact their livelihood and culture,” said Avinash Kumar Chanchal, a grassroots climate activist who has written on the degradation of the Singrauli coal belt and displacement of local communities. UN Secretary General Also Decries Coal Plans There is no good reason for any country to include coal in their #COVID19 recovery plans. This is the time to invest in energy sources that don’t pollute, generate decent jobs and save money. — António Guterres (@antonioguterres) June 29, 2020 United Nations Secretary-General Antonio Guterres has said there is no reason for any country to include coal in the COVID-19 recovery plans. Instead, investments should be made towards non-polluting energy sources; and opposition to a “black, coal-powered recovery” has grown in India. It isn’t clear whether this diplomatic rap on the knuckles and growing opposition will succeed in stopping the government in its polluting tracks, especially if Modi’s public statements on privatising coal mines – framed in his signature style with the bells and whistles of patriotism and nationalism for “atma-nirbharta” or self-reliance – are anything to go by. Desperate for funds and eager to kickstart a sluggish economy threatening to fall into a recession, the central government seems prepared to roadroll its way through. Its desperation stems from predictions of the most severe recession in the past the four decades – The International Monetary Fund has predicted a global annual downturn of 4.5%, though ratings firm India Ratings has predicted the Indian economy to contract by 5.3% this year. Renewable Energy Offers Untapped Potential Analysts say that the government is gambling on coal mining to generate over a million of jobs, as it is labour-intensive and rural communities are increasingly desperate for jobs following mass reverse migration since the pandemic began. Additionally, there is built-in momentum for coal power development, since it is already well-established and subsidized by the government – whereas renewables are a new game altogether, and energy storage issues still remain unresolved – as some critics claim. Activists and economists counter that government forces have ignored the potential of alternative energy sources at the current juncture: “There is huge potential to generate new jobs in renewable energy. Some analyses have estimated that more than one million jobs can be created by the renewable sector by 2022 if India can achieve its ambitious renewable target of 160GW,” said Chanchal. “The illusion of low cost energy from coal has been debunked globally. Socially, environmentally and economically, coal is very costly. It’s bad economic policy to invest in high cost options when cheaper alternatives exist today,” added Laveesh Bhandari, an economist turned environmental advocate, who works at the intersection of sustainable employment and climate change. “It’s almost as if we’re moving backwards. The whole world is moving away from coal. Several studies in India have shown the adverse effects of pollution caused by coal mining on the health of communities living within coal mining areas, especially on the respiratory system.” Even before pandemic, deaths from air pollution have been a major issue in India. In 2016, household pollution led to over a million deaths in India, according to the WHO’s Global Health Observatory; and in 2012, ambient air pollution claimed 620 000 Indian lives, with a shocking toll of over 20 million disability-adjusted life years (DALY), according to the WHO’s global assessment of exposure and burden of disease. However, now there is also the added factor of COVID-19, in which case chronic heavy exposures to air pollution will also increase vulnerability from the virus as well as mortality, said grassroots environmentalist and writer Rinchin, who goes by one name only and works with adivasis in Chhattisgarh. “Whether the Centre can still go ahead is a legal issue, but it will be bad form to go against the position of state governments. India is a federation, and something like mining that impacts not only the environment, but society itself therefore needs to be overseen, regulated and controlled by the state”, added Bhandari. India’s Ambition – Regional Energy Supplier? Coal mining in India While Modi is framing the coal auction as a move towards greater national self-reliance, the story is in fact more complex. His plan may involve ambitions to become a regional energy-producing power. It also aligns national policy with the commercial interests of close political allies – such as Indian billionaire Gautam Adani, and head of the powerful Adani group. Adani is leading the Carmichael project – a massive mining initiative to export Australian coal to India. Just last year, the Australia’s government gave the go-ahead for the project, the world’s largest open pit mine, overriding stiff opposition from Australian environmentalists. Adani plans to use the Australian coal for a new $2 billion power plant that his company is building in India, which will also produce electricity for sale in neighboring Bangladesh. Ever since Modi was the chief minister of the western state of Gujarat – Adani’s birthplace and home region – Adani and Modi were known to have close links. “The story of Adani and its Australian project illustrates why the world keeps burning coal despite its profound danger — and despite falling prices for options like natural gas, wind and solar,” the New York Times said last year. In fact, India’s coal ambitions under Modi will not just undermine existing efforts to limit climate change and worsen air and water pollution within the country, they are also likely to compromise the entire region, setting an undesirable example of fossil fuel dependency in neighbouring countries. Little Matter of Coal Gasification Air pollution in Delhi, India Then, there is that little matter of Modi’s plans for coal gasification – a technology that could further reduce India’s dependence on imports, but at an even higher level of carbon emissions – as well as potential water contamination from coal pollutants. The government’s current plan is to promote “syngas” -a substitute for imported liquified natural gas produced by coal gasification – to produce urea in fertilizer. This will not only help reduce liquified natural gas (LNG) imports but also urea imports, leading to a lower import bill and greater self-reliance. According to the Ministry of Chemicals and Fertilisers, urea is currently produced using pooled natural gas, which consists of both domestic natural gas and imported LNG. The usage of locally available coal for making fertilisers would help reduce the import of LNG, the Ministry has said. “The big question is when we have cleaner, cheaper, and sustainable renewable energy sources why do we want to invest in dirty and polluting technologies and energy sources? India is already facing a climate crisis,” said Chanchal. While natural gas is considered a lower climate emitter than coal, syngas is just the opposite. A study by Duke University found that syngas produced by coal gasification emits seven times more greenhouse gases than natural gas, making it a huge contributor to climate change. “It contaminates both surface water and groundwater, and also emits greenhouse gases. If renewable energy is available and becoming cheaper day by day, then why does the government want to start commercial mining to create coal based energy.” “Right now, the government is speaking like a climate leader but acting like a climate laggard by betting high on coal and promoting it,” added Bhatt. Mining Could Also Increase Dangerous Human-Wildlife Conflicts Dog sleeps on a bed of coal in Asansol, India Along with the climate and air pollution risks, activists have also warned that expanding mining operations in the areas up for auction could trigger increased human-wildlife conflict. “Among the 41 coal mines up for auction, most are situated in the dense forest of central India,” said Chanchal. “These forests are home to large populations of elephants and other wildlife. Some proposed coal blocks are also near tiger reserves, like in Maharashtra. “Along with vast forest destruction, coal mines will also increase the human-wildlife conflict. The implications are countless from the displacement of adivasis, to the violation of the Forest Rights Act, to public health,” said Chanchal, who has also written The Singrauli Files about the degradation of that region. “We have already seen how coal mines destroyed the rich biodiversity of places like Singrauli, Korba, and in other coal belts where thousands of adivasi and local communities were displaced, their forests, livelihood and human rights violated. They are already living with serious health crises,” he added. In a parallel move, Modi’s Ministry of Environment and Forestry also has launched an initiative to dilute existing environmental impact assessment norms for the creation of industries in pristine areas, including, but not limited to coal – a move that has been staunchly opposed by environmentalists – but action on that has been postponed by the courts until August. Modi Still Likely to Face Bureaucratic Challenges India’s Prime Minister Narendra Modi Despite the burgeoning opposition, Modi remains determined and eager to develop the private coal sector. Against the wave of new criticism he has remained silent – a typical tactic of response. However, India’s federal structure of governance may still slow down the realization of his vision considerably – giving environmentalist valuable time to mount a more organized local and global opposition. In the Indian governance model, the central government is expected to execute policy in consultation with state governments on a consensus model. More importantly, if the land is pristine forest land, as in this case, local self-governance laws and the FRA will make it challenging for it to move ahead with coal block allocation in such areas, which may still stave off this path to a quicker, but blacker, revival. “Land is a state subject, the Centre cannot go ahead without support from the states,” said Bhatt. “The implementation of the Forest Rights Act is also very crucial in these regions. The government which is promoting ‘atma-nirbhar Bharat’ should consider these concerns of local communities and take appropriate action to strengthen the self-governance of the gram sabha,” adds Chanchal. Image Credits: Environmental Change and Security Program, Flickr: Partha Sarathi Sahana, R. Pearce, T. Prater, S. Evans/Carbon Brief, Environmental Change and Security Program, Wikimedia Commons: Prami.ap90, Flickr: Partha Sarathi Sahana, Mike Bloomberg. World Surpasses 500,000 COVID-19 Deaths; Medicines Access Experts Challenge US $2340 Per Remdesivir Treatment Course Price Set By Gilead For Developed Countries 29/06/2020 Grace Ren Vial of remdesivir A six-vial five-day course of remdesivir – a promising COVID-19 treatment – will be priced at US $2340, or $390 per vial for developed countries, Gilead Sciences Chief Executive Officer Daniel O’Day wrote in an open letter on Monday. “Earlier hospital discharge [thanks to treatment by remdesivir] would result in hospital savings of approximately $12,000 per patient,” wrote O’Day. “We have decided to price remdesivir well below this value.” But the price is still high compared to the cost of manufacturing, according to medicines access experts, who say that remdesivir could be produced for below a dollar a day. Private insurers in the United States will pay US $3,120 for a five-day course, or $520 per vial. Out-of-pocket payments will be determined by individuals’ coverage plans. In 127 developing countries, Gilead has allowed generics companies to manufacture the drug, pricing a five-day course at about US $600. Cost of production for the drug can be as low as US $0.93 per day, according to a paper by Dr Andrew Hill, a senior visiting research fellow at the University of Liverpool, and his colleagues. “Gilead will turn a nice profit with its set price. Especially considering that the company has benefitted from significant government financing for the development of the drug; which apparently has not been discounted,” Ellen t’Hoen, director of Medicines, Law and Policy, told Health Policy Watch. electron microscope photo of SARS-CoV-2, the virus that causes COVID-19 “Based on publicly available data, it has been estimated that taxpayers have contributed at least $70.5 million to develop this drug,” Jessica Burry, a pharmacist at Médecins Sans Frontières Access Campaign, said to Health Policy Watch. “Additionally, contributions were made by various health organisations, including MSF, which supported clinical trials with this drug for Ebola in 2019. Patients themselves have also contributed by their participation in the trials. “Public funding and resources have contributed to the drug’s further development for COVID-19, and taxpayers will now end up essentially “paying twice” to access this treatment,” added Burry. The company could turn a US $2.3 billion profit on the “blockbuster” drug this year alone, according to a blog by Ellen t’Hoen. “This does put pharma’s lofty promises of not profiteering during the pandemic into perspective. I hope governments begin to realise that the important investments they make for the development of drugs and vaccines to respond to COVID-19 need to come with strings attached to ensure fair pricing and global access,” she said. COVID-19 Cases Surge Past 10,000,000, Deaths Reach Half A Million Meanwhile, the World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus warned on Monday that “the worst was yet to come.” Dr Tedros spoke at a press conference just as the number of deaths from COVID-19 topped half a million, and cumulative cases surged past 10,000,000. The US and Brazil continue to report around 40,000 new cases day. In the state of Texas, which saw one of the fastest rising daily case counts after reopening, hospitals in the capital city of Houston are nearing ICU capacity. Even as Vice President Mike Pence lauded the state’s reopening at a press briefing Monday, Texas Governor Greg Abbot warned that the epidemic had taken a “very swift and very dangerous turn.” Abbot shut down bars and clubs again across the state in an attempt to limit the fast-spreading virus. Remdesivir Pricing Announcement Comes On Heels Of EMA Conditional Marketing Authorization Endorsement Remdesivir, a failed Ebola antiviral, is one of the frontrunner drugs for treating COVID-19. It was shown to significantly reduce the length of hospital stay from an average of 11 days to an average of 15 days in a recent trial funded by the US National Institute of Allergies and Infectious Diseases (NIAID). However, the NIAID trial results were based on a 10-day treatment course, rather than the 5-day course that Gilead has currently priced. And studies have so far not reported any effects in reducing mortality. Still, the European Medicines Agency recently renewed their endorsement of the drug, recommending the agency give remdesivir conditional marketing authorization – a stamp of approval that many European Union countries use as guidance for approving drugs for diseases with few cures. Remdesivir is currently approved for use in Japan for COVID-19 patients. The United States Food and Drug Administration has approved the treatment for ’emergency’ use, just two days after the NIAID trial results were announced. The announcement comes just as Gilead’s promise to donate remdesivir until the end of June 2020 hits its deadline. US Health and Human Services Secretary Alex Azar announced Monday that the government had secured another half a million treatment courses of remdesivir for U.S. hospitals through September, according to an interview with “Good Morning America.” Health and Human Services will be paying the US $390 per vial price, and be responsible for allocating Gilead’s supply of remdesivir, according to O’Day’s letter. But some middle income countries that are hoping to secure their own supply of remdesivir may be out of luck, according to Burry. “Gilead has entered into license agreements with several generic companies in India, Pakistan and Egypt. The license, however, excludes nearly half of the world’s population, including most South American countries and a number of middle-income countries, such as Brazil, Russia and China,” said Burry. “Since the corporation has barely been able to supply enough quantities of this drug even to the US, it is highly unlikely that it will be able to meet the demands of all the other countries that have not been included in this license.” Brazil Signs Contract To Produce AstraZeneca & Oxford COVID-19 Vaccine Candidate; China Approves CanSino Vaccine Candidate For Military Use In a parallel development, Brazil on Saturday signed a contract with AstraZeneca and Oxford to manufacture an experimental COVID-19 vaccine candidate. Meanwhile, China approved the CanSino COVID-19 vaccine candidate for military use on Thursday. Local vaccine manufacturer Fiocruz will be producing up to 100 million doses of the vaccine overall, Brazilian authorities announced at a press briefing. The country will pay $127 million to receive material to produce 30.4 million doses in two batches in December and January, with the rest to come later. China’s Central Military Commission approved the CanSino vaccine for use by the military for a period of one year beginning 25 June 2020, according to a CanSino filing. The Academy of Military Sciences had jointly developed the vaccine candidate with CanSino. Results from a small, non-randomized trial released in May found that about 75% of people who received high doses of the CanSino vaccine candidate developed antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, after 28 days. However, the developers highlight that large, randomized control trials must be done in order to determine if the vaccine truly protects against infection by the virus. And other researchers pointed to old concerns with the Ad5 vector used in the CanSino vaccine. Previous Ad5-vectored vaccine candidates for HIV were dropped after early trials showed the experimental vaccine inadvertently increased the risk of HIV infection. This story was updated 30 June 2020. Image Credits: European Medicines Agency, NIAID, World Health Organization, NIAID. Gender-Based Violence – The “Shadow Pandemic” Of COVID-19 26/06/2020 Paul Adepoju While a face mask could provide some protection against COVID-19, the lives of many women in Africa, and elsewhere, are at the mercy of their abusers. (Photo Credit: Paul Adepoju) Ibadan, Nigeria – Twenty-two year-old Uwaila Vera Omozuwa, freshly admitted to university, had retreated to study in a church in the city of Benin, Nigeria during lockdown, when she was raped and killed on May 30. The following day, 18-year-old Barakat Bello was reportedly raped and killed in Oyo state. 29-year-old Azeezat Shomuyiwa and 21-year-old Grace Oshiagwu also suffered similar fates just days and few streets apart. In late March 2020, a video from Ghana surfaced on social media showing a boyfriend assaulting his girlfriend. As the COVID-19 pandemic continues to expand globally, African countries as well as other nations worldwide are also dealing with another related pandemic – that of gender-based violence. The stress triggered by COVID-19 lockdowns and economic uncertainty is exacerbating violent assaults, according to experts speaking at a panel last week hosted by the WHO Regional Office for Africa. Effectively, the pandemic has forced many women who are in abusive relationships to remain shut up at home with their abusers, further escalating their risks, they said. Social media responses condemning the gruesome murder and rape of Vera Uwaila Omozuwa. (Photo Credit: Youth Alive Foundation ) A “Shadow Pandemic” Gender-based violence is a “shadow pandemic” to COVID-19 said UN Women’s Executive Director, Phumzile Mlambo-Ngcuka. She noted that in Africa as well as elsewhere in the world, domestic violence hotlines and shelters are reporting rising calls for help. “Confinement is fostering the tension and strain created by security, health, and money worries. And it is increasing isolation for women with violent partners, separating them from the people and resources that can best help them,” Mlambo-Ngcuka said in a statement on violence against women and girls. “It’s a perfect storm for controlling, violent behaviour behind closed doors. And in parallel, as health systems are stretching to breaking point, domestic violence shelters are also reaching capacity, a service deficit made worse when centres are repurposed for additional COVID-response.” Africa has struggled with social attitudes sanctioning violent attacks on women, well before the pandemic began. For instance, in 2017, researchers at the University of Ghana reported that men who were in consensual unions or customary marriages remained in favour of wife beating. Police attitudes are often lax as well. Following Uwaila’s rape and murder in Benin, Nigeria, for instance, the local police initially demanded a “mobilization money” from the family to open an investigation, according to the victim’s sister, who finally led a protest to the Edo State police headquarters to trigger action – which she videotaped on Instagram. Now, in the period of COVID-19, for every 3 months lockdowns are imposed or continue, an additional 15 million extra cases of gender-based violence could be recorded worldwide, states a new report, COVID-19: A Gender Lens, by the UN Population Fund (UNFPA). And six months of lockdown could result in additional 31 million cases of gender-based violence in the world. Photo Credit: UN Women While the most extreme outcome, gender-based violence is not the only way women are suffering from lockdown restrictions, noted Dr. Natalia Kanem, UNFPA Executive Director while unveiling a new analysis by UNFPA and partners. “Millions more women and girls now risk losing the ability to plan their families and protect their bodies and their health,” she said, noting that women often cannot get to health services for basic care. “Women’s reproductive health and rights must be safeguarded at all costs. The services must continue; the supplies must be delivered; and the vulnerable must be protected and supported.” Fighting the Shadow Pandemic In Africa, political leaders have generally been reluctant to make themselves the face of campaigns against gender-based violence, the panel participants observed, recommending that Africa’s political leaders need to start speaking up now. “African leaders need to declare this situation as another pandemic and appeal to people, men, society, and those who set norms. African leaders need to speak up and recognise this is happening,” said Dr Matshidiso Moeti, WHO African Regional Director while speaking on the panel. Governments also need to make gender-violence prevention initiatives integral to economic and healthcare programmes dealing with COVID-19, she said. Matshidiso Moeti Specifically, she mentioned that police officers and health workers in African countries need to be made aware of the roles they are supposed to play in prevention of gender-based violence. For countries that are still in the dark over what to do, she noted that the government can work with men and women groups to improve the level of public education, provision of call numbers to report cases of abuse, and establishment of shelters to provide help and services to victims. “These can be part of the socio-economic response to the pandemic,” Moeti added. While most African countries now have legislation against gender-based violence, political leadership is still missing, agreed Winnie Byanyima, Executive Director of the Joint United Nations Programme on HIV/AIDS (UNAIDS). “I so rarely hear a male African leader speaking and leading on this issue. Most African leaders leave it to others, yet it is a pandemic – a silent one too,” Byanyima said. For Africa to advance in tackling gender-based violence, African leaders must be saddled with the responsibility of providing political leadership, she said. One leader that has spoken up recently was South African President Cyril Ramaphosa, a political powerful voice, as he is also the head of the African Union. Speaking to the media last week, he blamed the reopening of liquor stores as lockdown measures eased for a spate of attacks on women in that country. Those included pregnant, Tshegofatso Pule who was found hanging from a tree, Naledi Phangindawo, who was stabbed, and Sanele Mfaba whose body was later found in a Soweto township. South African campaigners note that in fact violence against women shot up from the moment the lockdowns began. The police force’s gender-based violence hotline received 2,300 calls in the first five days – nearly three times the rate prior to lockdown. Even so, Ramaphosa’s remarks were significant as this represented one of the few instances when an African Head of State has spoken out forcefully on the issue. Community-based Prevention and Education Are Key While some actions are being taken to improve Africa’s response to gender-based violence including building police and judiciary systems that understand their roles and can prosecute cases of gender-based violence, more needs to be done about awareness-raising and education that can prevent crimes from ever occurring, stressed Byanyima. “In my view, we are weakest on prevention. You need aggressive campaigns discouraging violent behaviors of boys and men, especially the way they see their masculinity and how they exercise it. That discouragement still needs to happen,” Byanyima said. Presently, this duty is largely left to civil societies and women organisations, but Byanyima noted that it is the business of the government to invest in continual campaigning in communities to change how relationships can be managed without violence. Winnie Byanyima “This is about men’s behavior – the way men are raised and see themselves as men. Tackling toxic masculinity is something that is not well invested in,” she said. Another necessary action to tackle the silent pandemic is to empower girls and women in African societies. Citing data from HIV, the UNAIDS Executive Director noted that an African girl’s vulnerability to HIV, sexual violence, unintended pregnancy and early marriage reduce by up to 50% if she is able to complete high school. But while African leaders have ratified universal basic education requiring every child to get at least primary education, two-thirds of children in Africa do not have access to secondary education. “The time for secondary education has come. We fought for universal primary education in Beijing and within ten years we have achieved it. Now we need to draw the line and say every government worth its name must put its kids, boys and girls, through high school. Not only for the knowledge economy but also for the safety and empowerment of girls and fighting gender-based violence,” Byanyima said. Story of Success: Experts Laud Rwanda’s One Stop Center For Sexual Violence Bineta Diop, African Union’s Special Envoy on Women Peace & Security, recommended African governments adopting Rwanda’s one-stop center for sexual violence. Located within the Kacyiru Police Hospital, the Isange One Stop Centre, the Isange One Stop Center has become a hub for gender-based violence survivors. At the center, survivors can access all the required services in one place and for free. The center is operated by the country’s Gender and Family Promotion, of Health, and Justice ministries in addition to the Rwanda National Police. Bineta Diop The initiative that started in 2009 as a pilot has since been expanded across the country. Rwanda now has a One Stop Centre in every district. Every day, up to 12 survivors are received at the center. “28% are survivors of intimate partner violence and 78 percent are survivors of sexual violence. Of the 78% of survivors who have been sexually assaulted, 16% are younger than 5 years,” said Daniel Nyamwasa, Commissioner of Police and Chief Infectologist Consultant at the hospital. Diop also encouraged African governments to acquire DNA testing capabilities to provide evidence that could be used to prosecute cases of rape and other gender-based violence against women and girls. Enlisting More Women in Police and Judiciary Another solution is the enlistment of more women in the police and judiciary systems across the continent which Diop said will encourage more women to approach the legal system to file complaints. She also called for the engagement of Africa’s traditional leaders. “If you want to break the patriarchal system, you have to engage the traditional system,” Diop said. However, as the number of confirmed cases of COVID-19 in Africa is increasing, African governments are also focusing on how to quickly and safely reopen their economies to minimize the impact of the pandemic. This current reality threatens the materialization of recommendations giving more attention to combating gender-based violence. But Ramaphosa, for one, has said this does not have to be the case. In his comments last week, he stressed that action can and should be taken to combat violence, despite the numerous familiar and peculiar challenges that countries across the continent are facing: “For public faith in the criminal justice system to be maintained, gender-based violence needs to be treated with the urgency it deserves by our communities working together with our police.” Cyril Ramaphosa, President of South Africa Image Credits: Paul Adepoju, Twitter: Youth Alive Foundation, UN Women. Massive Mobilization Of US $31.3 Billion Required For COVID-19 Diagnostics, Drugs & Vaccines Accelerator 26/06/2020 Grace Ren Central Laboratory at the Academician Nikoloz Kipshidze University Clinic, Tbilisi, Georgia, receives laboratory equipment for COVID-19 diagnosis. The World Health Organization aims to raise a whopping US $31.3 billion to fund the ambitious goals of the Access to COVID-19 Tools (ACT) Accelerator; a multi-stakeholder initiative that aims to develop and deploy diagnostics, drugs, and vaccines to control the virus. But so far, only $US 3.4 billion has been pledged towards the initial goals. And US $13.7 billion is ‘urgently needed’ in order to cover immediate needs, according to an investment case released by WHO on Friday. “Though these numbers sound big, they are not. If we spend billions now, we will avoid spending trillions later. The time to act is now, and the way to act is together,” said Gavi Board Chair Ngozi Okonjo-Iweala. The funding will go toward: Scaling up development and delivery of 500 million diagnostic tests to low- and middle-income countries (LMICS) by mid-2021 Delivering 245 million courses of treatments to LMICs by mid-2021, Delivering 2 billion vaccine doses, of which 50% will go to LMICs by the end of 2021. “It’s clear that because all people are at risk of COVID-19, all people should have access to all the tools to prevent, detect and treated, not only those who can afford to pay for them,” said World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus at a Friday press briefing. “We have made the principle of equitable access a simple thing to say, but a complicated thing to implement.” Dr Tedros at the 26 June press briefing More than 9 million people have been infected, and nearly half a million have so far lost their lives to the virus. The investment required in the Accelerator is less than a tenth of the loss the global economy is facing every month due to the pandemic, according to International Monetary Fund estimates. “The cost of inaction now is quite important to take into consideration,” said Philippe Duneton, executive director of UNITAID, working with the Wellcome Trust on the therapeutics pillar of the project. A good portion of the immediate investments will go towards preparing markets to absorb new COVID-19 technologies, setting up demand, manufacturing, and country capacity to roll out any new diagnostics, vaccines, or drugs. Four Investment Pillars Require Urgent Funding The ACT Accelerator operates under four main pillars – diagnostics, therapeutics, vaccines, and the health systems connector. The diagnostics pillar, co-led by FIND and the Global Fund to Fight AIDS, Tuberculosis, and Malaria, aims to avoid 1.6 billion further infections by scaling up access to diagnostics. The pillar requires US $6 billion in the next year, but US $2 billion is urgently needed to begin deploying tests now. Ultimately, 10,000 healthcare workers will be needed. “The real strategy towards containing the epidemic is through testing, tracing, isolation; and the starting point for that is a very rapid rollout of very large numbers of tests,” said Peter Sands, executive director of the Global Fund. “To underscore the urgency for many lower middle income countries, lockdown is not sustainable. Households don’t have the wherewithal to continue without working, and governments don’t have the ability to compensate for lost income, coupled with the fact that clinical care facilities are extremely limited.” The therapeutics pillar will focus on accelerating the development and deployment of effective treatments. While no drugs have yet been tapped, the pillar aims to provide 250 million courses of treatment to LMICS in the next 12 months. Some US$11.6 billion is needed in the next year, while US $3.8 billion is needed immediately. “Of course, as soon as we have a medicine, the situation at the country level will also be a challenge,” said Duneton. “The access to oxygen, for example, is not the same in all countries.” But “the only way to prevent further transmission [of the virus] and to break that cycle, would be to have an effective and safe vaccine available to people,” said WHO Chief Scientist Soumya Swaminathan. Soumya Swaminathan speaks at the 26 June ACT Accelerator press briefing The vaccines pillar has an ambitious goal of delivering 2 billion doses by the end of 2021. Seven candidates are currently in clinical trials, but none have yet received regulatory approval. So far, the fastest vaccine to move from lab bench to approval for human use was the Ebola vaccine – which took five years to develop. “In general, it takes 8 to 10 years for a vaccine to move from when the research begins to when it gets into people. We want to shorten that timeline as short as possible – 12 months, 18 months maximum,” said Swaminathan. “That would be unprecedented, and can only happen through global collaboration.” The Coalition for Epidemic Preparedness Innovation (CEPI), and Gavi, the Vaccine Alliance, will lead the vaccines pillar alongside WHO, which will provide oversight of regulation, policy and allocation. Some US $18.1 billion is required to safely deliver the vaccine to people in need. Gavi, through an advanced market agreement under its COVAX Facility, aims to pool purchasing power from nations of all income levels to secure low vaccine prices. Some 950 million doses must be procured by self-financing, upper-middle and high income countries, in addition to the 2 billion doses set aside for lower income countries. A final pillar, the health systems connector, aims to strengthen the infrastructure and community networks required to deliver tools to people in need. Led by the World Bank, and the Global Fund, the pillar aims to build lab capacity, train staff to safely manage COVID-19, and to use new tools as they are deployed. Image Credits: Flickr: IAEA Imagebank/Natalia Khurtsidze, PR Manager of the Clinic. Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts This site uses cookies to help give you the best experience on our website. Cookies enable us to collect information that helps us personalise your experience and improve the functionality and performance of our site. By continuing to read our website, we assume you agree to this, otherwise you can adjust your browser settings. Please read our cookie and Privacy Policy. Our Cookies and Privacy Policy Loading Comments... You must be logged in to post a comment.
Pfizer COVID-19 Vaccine Shows Promising Early Results; Induces Immune Response In Healthy Volunteers 01/07/2020 Grace Ren Manufacturing COVID-19 vaccine at Pfizer A COVID-19 vaccine candidate under development by pharma giant Pfizer and biotech firm BioNTech showed promise in interim results released Wednesday. The vaccine candidate, BNT162b1, was able to induce the formation of antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, in all participants who received doses between 10ug to 30ug, according to a report posted on the preprint server MedRxiv. The report has not yet been peer-reviewed. Seven days after the last injection, levels of neutralizing antibodies in those who received 10 µg and 30 µg of the vaccine 21 days apart were 1.8 to 2.8 times the level of neutralizing antibodies in recovered COVID-19 patients. “These preliminary data are encouraging in that they provide an initial signal that BNT162b1 targeting the RBD SARS-CoV-2 is able to produce neutralizing antibody responses in humans at or above the levels observed in convalescent sera – and that it does so at relatively low dose levels. We look forward to providing further data updates on BNT162b1,” said Ugur Sahin, M.D., CEO and Co-founder of BioNTech, in a press release. The study placed 45 healthy volunteers between the ages of 18 to 55 into three groups for the initial analysis. Some 24 subjects received two injections of 10 µg and 30 µg, 12 subjects received a single injection of 100 µg, and 9 subjects received 2 doses of placebo control. However, the study did not include results from adults over 65 years of age and pregnant women. Three-quarters of the subjects in the first group experienced acute low-grade fever below 100 degrees Celsius, and some experienced minor to moderate pain at the injection site. More trials must be done in order to test whether the vaccine can lower the likelihood of infection by 50%. But the preliminary results indicate that Phase ⅔ trials may be set to start in late July, as Pfizer Chief Executive Officer Albert Bourla told reporters in May. These trials may enroll up to 30,000 healthy volunteers The Pfizer vaccine is one of 14 candidates currently in human trials. It is based on messenger RNA, a single-stranded construct that carries a blueprint for a protein immune cells can then learn to attack, the same model as the Moderna vaccine candidate. The Moderna vaccine also showed promising early results, inducing neutralizing antibodies in a small group of early volunteers, but further results have yet to be released. Image Credits: Pfizer, Pfizer. World Health Organization Will Send Scoping Mission To China To Investigate COVID-19 Origins 30/06/2020 Editorial team Dr Tedros at a June 2020 press briefing The World Health Organization will be sending a mission to China on 6 July to investigate the origins of SARS-CoV-2, the virus that causes COVID-19, WHO Director-General Dr Tedros Adhanom Ghebreyesus subtly announced at a Monday press briefing. The mission aims to fulfill decisions made in a unanimously passed World Health Assembly resolution in late May, which requested WHO work with World Organisation for Animal Health (OIE), the Food and Agriculture Organization of the United Nations (FAO) and countries to “identify the zoonotic source of the virus and the route of introduction to the human population, including the possible role of intermediate hosts.” “We will send a team next week to China to prepare this and hopefully it will lead to a better understanding of how the virus started and what we can do in the future to prepare for it,” said Dr Tedros on Monday, in response to a query from a Brussel Times journalist following-up on the status of actions outlined in the resolution. Two WHO experts will be sent on the initial scoping mission; an expert in animal health and an epidemiology expert with a background in investigating epidemics in the field, WHO Health Emergencies Executive Director Mike Ryan added on Wednesday. While researchers largely believe that the virus jumped the animal-human barrier at a wet market in Wuhan, China, some have posited that the virus may have escaped from a high level virology lab within miles of the first cluster of confirmed cases. The quiet announcement underlines the political tensions surrounding the investigation of origins of the virus, with WHO caught in an ongoing feud between China and the United States. United States President Donald Trump has repeatedly slammed the World Health Organization for supposedly catering to China’s favor and delaying global responses to the pandemic, despite once praising the WHO and China response before COVID-19 reached US shores. Trump has made WHO’s supposed deference to China the main point of contention for withdrawing US support from the agency, even as the US continues to face an accelerating pandemic at home, reporting the highest numbers of new cases and hospitalizations daily. But WHO has little authority over Member States’ actions, and must balance criticising pandemic responses with retaining access to data and knowledge. The first WHO mission to China was delicately arranged at the end of January, after Chinese authorities locked down the Wuhan, a city of 11 million people, following a spike in cases due to a delayed response in early January. Since largely coming out of lockdown in May, the outbreak in China has been tightly controlled. However, new clusters of cases in Jilin province, Wuhan city, and the capital of Beijing have sparked great unease and second rounds of lockdowns. Swelling Indian National Opposition As Modi Plans To Expand Coal Mining 30/06/2020 Jyoti Pande Lavakare Coal miners in India’s resource-rich Meghalaya State. A government tribunal banned coal mining in the region in 2015. New Delhi, India – Prime Minister Narendra’s Modi’s ambitious plan to use coal to power India’s economic revival after his government’s strict lockdowns flattened the wrong curve, bringing economic growth to a halt even as the infection epidemic curve continued to rise, seems to have run into significant opposition from unexpected quarters. Since the launch of his plan earlier this month, state after Indian state has expressed disagreement with the Centre’s plan to commercially auction coal mines to the private sector, including international players. The latest to join the clamour of opposition by the states of Chhattisgarh, Jharkhand and Maharashtra, where more than half of the 41 mines are located – is the politically powerful chief minister of West Bengal, Mamata Banerjee. Indian environmentalists have also decried a seemingly desperate announcement by the government to auction off 41 Indian coal mines, opening a largely government-controlled sector up to all private investment for the first time ever – and thus greatly accelerating domestic coal production. Coal mining by Eastern Coalfields Ltd., the company that operates national coalfields in Jharkhand and West Bengal states. As of now, two government-owned mines produce over 90 % of India’s coal. Indian coal, known for its high fly ash content– and therefore pollution emissions – currently supplies about 80% of the country’s total coal needs, while the rest is imported. Coal, in turn, powers about 44% of the total energy needs, compared to oil (24%) and biomass (22%) – though the latter is often burned in highly polluting domestic cookstoves emitting climate-changing black carbon particles. Also, hydroelectric power supplies 1.4% of the economy, leaving solar and wind to supply only around 0.8% of the country’s total power needs. When it comes to electricity generation, the picture is just a little bit better. Coal powers 73% of electricity in India, while solar and wind fuel around 8% and hydro around 12% respectively, said Karthik Ganesan, Research Fellow, Council on Energy, Environment and Water. Clean air campaigners had hoped that the glimpse of blue skies, clean water bodies and nature restoring itself in the limbo provided by the lockdown of all growth engines would encourage decision-makers to choose a growth recovery path that had low environmental impact. Health and environmentalist activists had expected the government to look at growth recovery more holistically, which meant including developmental indicators like health, education and quality of life – in the spirit of the recent WHO manifesto for a healthy green recovery, which calls to put a stop to fossil fuel subsidies using taxpayer money. Unfortunately, India seems to be ignoring all of the recent health and climate warming signals – the latest being the swarms of locusts that are invading parts of the country as it focuses on coal to fuel its recovery. Ostensibly, Modi’s rationale is that the move will help make India energy self-sufficient and quickly claw back the robust growth curve that had begun to fall off even before the COVID-19 pandemic struck the country. However, investing heavily in coal also serves some of his key political alliances, some of whom – like the Adani Group – are also planning to export massive new coal reserves from Australia to India. Opposition to Modi’s Move Growing in India Existing, new, and planned coal mines in India (Credit: R. Pearce, T. Prater, S. Evans/Carbon Brief) Despite the pressing economic challenges that India admittedly does face, some leading Indian politicians are beginning to speak out in opposition to the coal mining plans – bringing this sector back into centre stage for the first time since “Coalgate,’ a coal scam that tainted the previous government a decade ago. Jharkhand state has already approached the Supreme Court challenging this auction, followed by Chhattisgarh and Maharashtra writing to the central environment minister Prakash Javadekar objecting to the auction. The latest to join the rising voice of critics is the feisty Chief Minister of West Bengal (and Modi’s bete noire) Mamata Banerjee, known for her blunt statements and ability to stand up to the central government. Last Thursday, Ms Banerjee wrote to Modi on Thursday, asking him to reconsider the decision, saying that “this policy can neither bring foreign direct investments not can it bring technologies or know-how which we are unable to access today,” and noting that global investors are more interested in renewable energy projects rather than coal, which offers low returns. None of the 41 mines coming up for auction are located in her state. Her objection is in principle and adds political weight to the growing opposition. States like Jharkhand, Maharashtra and Chhattisgarh, where more than half the mines coming up for auction are located, have already voiced opposition to this decision, citing huge environmental and social costs: “Riding on coal could spur the economy in the very short term and an extremely high ecological and social cost”, said Niraj Bhatt, Researcher in Environment and Climate Action for the Chennai-based Citizen consumer and civic Action Group (CAG), who works in the coal sector. The long term costs of promoting coal are disastrous, even in the government’s very first Climate Assessment report. The report warns of a four-fold increase in heat wave frequency and a doubling in the length of heat waves in India by 2100. “It is inexplicable why the government is prioritizing coal for fast track revival of the Indian economy since the pandemic”, given the knowledge that’s available, added Bhatt. Many local communities also are opposed to the government’s decision to privatize coal mining, fearing that this will degrade the environment. Most of the 41 coal mines in auction are in pristine forest areas. Even at the village-level, several panchayats (local governance bodies that make the fundamental building blocks of governance) have asked Modi to withdraw this auction. “Nine village panchayats from Hasdeo Arand forest region have written to the Prime-minister asking for withdrawing the auction of five coal blocks in the region for commercial mining as it would impact their livelihood and culture,” said Avinash Kumar Chanchal, a grassroots climate activist who has written on the degradation of the Singrauli coal belt and displacement of local communities. UN Secretary General Also Decries Coal Plans There is no good reason for any country to include coal in their #COVID19 recovery plans. This is the time to invest in energy sources that don’t pollute, generate decent jobs and save money. — António Guterres (@antonioguterres) June 29, 2020 United Nations Secretary-General Antonio Guterres has said there is no reason for any country to include coal in the COVID-19 recovery plans. Instead, investments should be made towards non-polluting energy sources; and opposition to a “black, coal-powered recovery” has grown in India. It isn’t clear whether this diplomatic rap on the knuckles and growing opposition will succeed in stopping the government in its polluting tracks, especially if Modi’s public statements on privatising coal mines – framed in his signature style with the bells and whistles of patriotism and nationalism for “atma-nirbharta” or self-reliance – are anything to go by. Desperate for funds and eager to kickstart a sluggish economy threatening to fall into a recession, the central government seems prepared to roadroll its way through. Its desperation stems from predictions of the most severe recession in the past the four decades – The International Monetary Fund has predicted a global annual downturn of 4.5%, though ratings firm India Ratings has predicted the Indian economy to contract by 5.3% this year. Renewable Energy Offers Untapped Potential Analysts say that the government is gambling on coal mining to generate over a million of jobs, as it is labour-intensive and rural communities are increasingly desperate for jobs following mass reverse migration since the pandemic began. Additionally, there is built-in momentum for coal power development, since it is already well-established and subsidized by the government – whereas renewables are a new game altogether, and energy storage issues still remain unresolved – as some critics claim. Activists and economists counter that government forces have ignored the potential of alternative energy sources at the current juncture: “There is huge potential to generate new jobs in renewable energy. Some analyses have estimated that more than one million jobs can be created by the renewable sector by 2022 if India can achieve its ambitious renewable target of 160GW,” said Chanchal. “The illusion of low cost energy from coal has been debunked globally. Socially, environmentally and economically, coal is very costly. It’s bad economic policy to invest in high cost options when cheaper alternatives exist today,” added Laveesh Bhandari, an economist turned environmental advocate, who works at the intersection of sustainable employment and climate change. “It’s almost as if we’re moving backwards. The whole world is moving away from coal. Several studies in India have shown the adverse effects of pollution caused by coal mining on the health of communities living within coal mining areas, especially on the respiratory system.” Even before pandemic, deaths from air pollution have been a major issue in India. In 2016, household pollution led to over a million deaths in India, according to the WHO’s Global Health Observatory; and in 2012, ambient air pollution claimed 620 000 Indian lives, with a shocking toll of over 20 million disability-adjusted life years (DALY), according to the WHO’s global assessment of exposure and burden of disease. However, now there is also the added factor of COVID-19, in which case chronic heavy exposures to air pollution will also increase vulnerability from the virus as well as mortality, said grassroots environmentalist and writer Rinchin, who goes by one name only and works with adivasis in Chhattisgarh. “Whether the Centre can still go ahead is a legal issue, but it will be bad form to go against the position of state governments. India is a federation, and something like mining that impacts not only the environment, but society itself therefore needs to be overseen, regulated and controlled by the state”, added Bhandari. India’s Ambition – Regional Energy Supplier? Coal mining in India While Modi is framing the coal auction as a move towards greater national self-reliance, the story is in fact more complex. His plan may involve ambitions to become a regional energy-producing power. It also aligns national policy with the commercial interests of close political allies – such as Indian billionaire Gautam Adani, and head of the powerful Adani group. Adani is leading the Carmichael project – a massive mining initiative to export Australian coal to India. Just last year, the Australia’s government gave the go-ahead for the project, the world’s largest open pit mine, overriding stiff opposition from Australian environmentalists. Adani plans to use the Australian coal for a new $2 billion power plant that his company is building in India, which will also produce electricity for sale in neighboring Bangladesh. Ever since Modi was the chief minister of the western state of Gujarat – Adani’s birthplace and home region – Adani and Modi were known to have close links. “The story of Adani and its Australian project illustrates why the world keeps burning coal despite its profound danger — and despite falling prices for options like natural gas, wind and solar,” the New York Times said last year. In fact, India’s coal ambitions under Modi will not just undermine existing efforts to limit climate change and worsen air and water pollution within the country, they are also likely to compromise the entire region, setting an undesirable example of fossil fuel dependency in neighbouring countries. Little Matter of Coal Gasification Air pollution in Delhi, India Then, there is that little matter of Modi’s plans for coal gasification – a technology that could further reduce India’s dependence on imports, but at an even higher level of carbon emissions – as well as potential water contamination from coal pollutants. The government’s current plan is to promote “syngas” -a substitute for imported liquified natural gas produced by coal gasification – to produce urea in fertilizer. This will not only help reduce liquified natural gas (LNG) imports but also urea imports, leading to a lower import bill and greater self-reliance. According to the Ministry of Chemicals and Fertilisers, urea is currently produced using pooled natural gas, which consists of both domestic natural gas and imported LNG. The usage of locally available coal for making fertilisers would help reduce the import of LNG, the Ministry has said. “The big question is when we have cleaner, cheaper, and sustainable renewable energy sources why do we want to invest in dirty and polluting technologies and energy sources? India is already facing a climate crisis,” said Chanchal. While natural gas is considered a lower climate emitter than coal, syngas is just the opposite. A study by Duke University found that syngas produced by coal gasification emits seven times more greenhouse gases than natural gas, making it a huge contributor to climate change. “It contaminates both surface water and groundwater, and also emits greenhouse gases. If renewable energy is available and becoming cheaper day by day, then why does the government want to start commercial mining to create coal based energy.” “Right now, the government is speaking like a climate leader but acting like a climate laggard by betting high on coal and promoting it,” added Bhatt. Mining Could Also Increase Dangerous Human-Wildlife Conflicts Dog sleeps on a bed of coal in Asansol, India Along with the climate and air pollution risks, activists have also warned that expanding mining operations in the areas up for auction could trigger increased human-wildlife conflict. “Among the 41 coal mines up for auction, most are situated in the dense forest of central India,” said Chanchal. “These forests are home to large populations of elephants and other wildlife. Some proposed coal blocks are also near tiger reserves, like in Maharashtra. “Along with vast forest destruction, coal mines will also increase the human-wildlife conflict. The implications are countless from the displacement of adivasis, to the violation of the Forest Rights Act, to public health,” said Chanchal, who has also written The Singrauli Files about the degradation of that region. “We have already seen how coal mines destroyed the rich biodiversity of places like Singrauli, Korba, and in other coal belts where thousands of adivasi and local communities were displaced, their forests, livelihood and human rights violated. They are already living with serious health crises,” he added. In a parallel move, Modi’s Ministry of Environment and Forestry also has launched an initiative to dilute existing environmental impact assessment norms for the creation of industries in pristine areas, including, but not limited to coal – a move that has been staunchly opposed by environmentalists – but action on that has been postponed by the courts until August. Modi Still Likely to Face Bureaucratic Challenges India’s Prime Minister Narendra Modi Despite the burgeoning opposition, Modi remains determined and eager to develop the private coal sector. Against the wave of new criticism he has remained silent – a typical tactic of response. However, India’s federal structure of governance may still slow down the realization of his vision considerably – giving environmentalist valuable time to mount a more organized local and global opposition. In the Indian governance model, the central government is expected to execute policy in consultation with state governments on a consensus model. More importantly, if the land is pristine forest land, as in this case, local self-governance laws and the FRA will make it challenging for it to move ahead with coal block allocation in such areas, which may still stave off this path to a quicker, but blacker, revival. “Land is a state subject, the Centre cannot go ahead without support from the states,” said Bhatt. “The implementation of the Forest Rights Act is also very crucial in these regions. The government which is promoting ‘atma-nirbhar Bharat’ should consider these concerns of local communities and take appropriate action to strengthen the self-governance of the gram sabha,” adds Chanchal. Image Credits: Environmental Change and Security Program, Flickr: Partha Sarathi Sahana, R. Pearce, T. Prater, S. Evans/Carbon Brief, Environmental Change and Security Program, Wikimedia Commons: Prami.ap90, Flickr: Partha Sarathi Sahana, Mike Bloomberg. World Surpasses 500,000 COVID-19 Deaths; Medicines Access Experts Challenge US $2340 Per Remdesivir Treatment Course Price Set By Gilead For Developed Countries 29/06/2020 Grace Ren Vial of remdesivir A six-vial five-day course of remdesivir – a promising COVID-19 treatment – will be priced at US $2340, or $390 per vial for developed countries, Gilead Sciences Chief Executive Officer Daniel O’Day wrote in an open letter on Monday. “Earlier hospital discharge [thanks to treatment by remdesivir] would result in hospital savings of approximately $12,000 per patient,” wrote O’Day. “We have decided to price remdesivir well below this value.” But the price is still high compared to the cost of manufacturing, according to medicines access experts, who say that remdesivir could be produced for below a dollar a day. Private insurers in the United States will pay US $3,120 for a five-day course, or $520 per vial. Out-of-pocket payments will be determined by individuals’ coverage plans. In 127 developing countries, Gilead has allowed generics companies to manufacture the drug, pricing a five-day course at about US $600. Cost of production for the drug can be as low as US $0.93 per day, according to a paper by Dr Andrew Hill, a senior visiting research fellow at the University of Liverpool, and his colleagues. “Gilead will turn a nice profit with its set price. Especially considering that the company has benefitted from significant government financing for the development of the drug; which apparently has not been discounted,” Ellen t’Hoen, director of Medicines, Law and Policy, told Health Policy Watch. electron microscope photo of SARS-CoV-2, the virus that causes COVID-19 “Based on publicly available data, it has been estimated that taxpayers have contributed at least $70.5 million to develop this drug,” Jessica Burry, a pharmacist at Médecins Sans Frontières Access Campaign, said to Health Policy Watch. “Additionally, contributions were made by various health organisations, including MSF, which supported clinical trials with this drug for Ebola in 2019. Patients themselves have also contributed by their participation in the trials. “Public funding and resources have contributed to the drug’s further development for COVID-19, and taxpayers will now end up essentially “paying twice” to access this treatment,” added Burry. The company could turn a US $2.3 billion profit on the “blockbuster” drug this year alone, according to a blog by Ellen t’Hoen. “This does put pharma’s lofty promises of not profiteering during the pandemic into perspective. I hope governments begin to realise that the important investments they make for the development of drugs and vaccines to respond to COVID-19 need to come with strings attached to ensure fair pricing and global access,” she said. COVID-19 Cases Surge Past 10,000,000, Deaths Reach Half A Million Meanwhile, the World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus warned on Monday that “the worst was yet to come.” Dr Tedros spoke at a press conference just as the number of deaths from COVID-19 topped half a million, and cumulative cases surged past 10,000,000. The US and Brazil continue to report around 40,000 new cases day. In the state of Texas, which saw one of the fastest rising daily case counts after reopening, hospitals in the capital city of Houston are nearing ICU capacity. Even as Vice President Mike Pence lauded the state’s reopening at a press briefing Monday, Texas Governor Greg Abbot warned that the epidemic had taken a “very swift and very dangerous turn.” Abbot shut down bars and clubs again across the state in an attempt to limit the fast-spreading virus. Remdesivir Pricing Announcement Comes On Heels Of EMA Conditional Marketing Authorization Endorsement Remdesivir, a failed Ebola antiviral, is one of the frontrunner drugs for treating COVID-19. It was shown to significantly reduce the length of hospital stay from an average of 11 days to an average of 15 days in a recent trial funded by the US National Institute of Allergies and Infectious Diseases (NIAID). However, the NIAID trial results were based on a 10-day treatment course, rather than the 5-day course that Gilead has currently priced. And studies have so far not reported any effects in reducing mortality. Still, the European Medicines Agency recently renewed their endorsement of the drug, recommending the agency give remdesivir conditional marketing authorization – a stamp of approval that many European Union countries use as guidance for approving drugs for diseases with few cures. Remdesivir is currently approved for use in Japan for COVID-19 patients. The United States Food and Drug Administration has approved the treatment for ’emergency’ use, just two days after the NIAID trial results were announced. The announcement comes just as Gilead’s promise to donate remdesivir until the end of June 2020 hits its deadline. US Health and Human Services Secretary Alex Azar announced Monday that the government had secured another half a million treatment courses of remdesivir for U.S. hospitals through September, according to an interview with “Good Morning America.” Health and Human Services will be paying the US $390 per vial price, and be responsible for allocating Gilead’s supply of remdesivir, according to O’Day’s letter. But some middle income countries that are hoping to secure their own supply of remdesivir may be out of luck, according to Burry. “Gilead has entered into license agreements with several generic companies in India, Pakistan and Egypt. The license, however, excludes nearly half of the world’s population, including most South American countries and a number of middle-income countries, such as Brazil, Russia and China,” said Burry. “Since the corporation has barely been able to supply enough quantities of this drug even to the US, it is highly unlikely that it will be able to meet the demands of all the other countries that have not been included in this license.” Brazil Signs Contract To Produce AstraZeneca & Oxford COVID-19 Vaccine Candidate; China Approves CanSino Vaccine Candidate For Military Use In a parallel development, Brazil on Saturday signed a contract with AstraZeneca and Oxford to manufacture an experimental COVID-19 vaccine candidate. Meanwhile, China approved the CanSino COVID-19 vaccine candidate for military use on Thursday. Local vaccine manufacturer Fiocruz will be producing up to 100 million doses of the vaccine overall, Brazilian authorities announced at a press briefing. The country will pay $127 million to receive material to produce 30.4 million doses in two batches in December and January, with the rest to come later. China’s Central Military Commission approved the CanSino vaccine for use by the military for a period of one year beginning 25 June 2020, according to a CanSino filing. The Academy of Military Sciences had jointly developed the vaccine candidate with CanSino. Results from a small, non-randomized trial released in May found that about 75% of people who received high doses of the CanSino vaccine candidate developed antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, after 28 days. However, the developers highlight that large, randomized control trials must be done in order to determine if the vaccine truly protects against infection by the virus. And other researchers pointed to old concerns with the Ad5 vector used in the CanSino vaccine. Previous Ad5-vectored vaccine candidates for HIV were dropped after early trials showed the experimental vaccine inadvertently increased the risk of HIV infection. This story was updated 30 June 2020. Image Credits: European Medicines Agency, NIAID, World Health Organization, NIAID. Gender-Based Violence – The “Shadow Pandemic” Of COVID-19 26/06/2020 Paul Adepoju While a face mask could provide some protection against COVID-19, the lives of many women in Africa, and elsewhere, are at the mercy of their abusers. (Photo Credit: Paul Adepoju) Ibadan, Nigeria – Twenty-two year-old Uwaila Vera Omozuwa, freshly admitted to university, had retreated to study in a church in the city of Benin, Nigeria during lockdown, when she was raped and killed on May 30. The following day, 18-year-old Barakat Bello was reportedly raped and killed in Oyo state. 29-year-old Azeezat Shomuyiwa and 21-year-old Grace Oshiagwu also suffered similar fates just days and few streets apart. In late March 2020, a video from Ghana surfaced on social media showing a boyfriend assaulting his girlfriend. As the COVID-19 pandemic continues to expand globally, African countries as well as other nations worldwide are also dealing with another related pandemic – that of gender-based violence. The stress triggered by COVID-19 lockdowns and economic uncertainty is exacerbating violent assaults, according to experts speaking at a panel last week hosted by the WHO Regional Office for Africa. Effectively, the pandemic has forced many women who are in abusive relationships to remain shut up at home with their abusers, further escalating their risks, they said. Social media responses condemning the gruesome murder and rape of Vera Uwaila Omozuwa. (Photo Credit: Youth Alive Foundation ) A “Shadow Pandemic” Gender-based violence is a “shadow pandemic” to COVID-19 said UN Women’s Executive Director, Phumzile Mlambo-Ngcuka. She noted that in Africa as well as elsewhere in the world, domestic violence hotlines and shelters are reporting rising calls for help. “Confinement is fostering the tension and strain created by security, health, and money worries. And it is increasing isolation for women with violent partners, separating them from the people and resources that can best help them,” Mlambo-Ngcuka said in a statement on violence against women and girls. “It’s a perfect storm for controlling, violent behaviour behind closed doors. And in parallel, as health systems are stretching to breaking point, domestic violence shelters are also reaching capacity, a service deficit made worse when centres are repurposed for additional COVID-response.” Africa has struggled with social attitudes sanctioning violent attacks on women, well before the pandemic began. For instance, in 2017, researchers at the University of Ghana reported that men who were in consensual unions or customary marriages remained in favour of wife beating. Police attitudes are often lax as well. Following Uwaila’s rape and murder in Benin, Nigeria, for instance, the local police initially demanded a “mobilization money” from the family to open an investigation, according to the victim’s sister, who finally led a protest to the Edo State police headquarters to trigger action – which she videotaped on Instagram. Now, in the period of COVID-19, for every 3 months lockdowns are imposed or continue, an additional 15 million extra cases of gender-based violence could be recorded worldwide, states a new report, COVID-19: A Gender Lens, by the UN Population Fund (UNFPA). And six months of lockdown could result in additional 31 million cases of gender-based violence in the world. Photo Credit: UN Women While the most extreme outcome, gender-based violence is not the only way women are suffering from lockdown restrictions, noted Dr. Natalia Kanem, UNFPA Executive Director while unveiling a new analysis by UNFPA and partners. “Millions more women and girls now risk losing the ability to plan their families and protect their bodies and their health,” she said, noting that women often cannot get to health services for basic care. “Women’s reproductive health and rights must be safeguarded at all costs. The services must continue; the supplies must be delivered; and the vulnerable must be protected and supported.” Fighting the Shadow Pandemic In Africa, political leaders have generally been reluctant to make themselves the face of campaigns against gender-based violence, the panel participants observed, recommending that Africa’s political leaders need to start speaking up now. “African leaders need to declare this situation as another pandemic and appeal to people, men, society, and those who set norms. African leaders need to speak up and recognise this is happening,” said Dr Matshidiso Moeti, WHO African Regional Director while speaking on the panel. Governments also need to make gender-violence prevention initiatives integral to economic and healthcare programmes dealing with COVID-19, she said. Matshidiso Moeti Specifically, she mentioned that police officers and health workers in African countries need to be made aware of the roles they are supposed to play in prevention of gender-based violence. For countries that are still in the dark over what to do, she noted that the government can work with men and women groups to improve the level of public education, provision of call numbers to report cases of abuse, and establishment of shelters to provide help and services to victims. “These can be part of the socio-economic response to the pandemic,” Moeti added. While most African countries now have legislation against gender-based violence, political leadership is still missing, agreed Winnie Byanyima, Executive Director of the Joint United Nations Programme on HIV/AIDS (UNAIDS). “I so rarely hear a male African leader speaking and leading on this issue. Most African leaders leave it to others, yet it is a pandemic – a silent one too,” Byanyima said. For Africa to advance in tackling gender-based violence, African leaders must be saddled with the responsibility of providing political leadership, she said. One leader that has spoken up recently was South African President Cyril Ramaphosa, a political powerful voice, as he is also the head of the African Union. Speaking to the media last week, he blamed the reopening of liquor stores as lockdown measures eased for a spate of attacks on women in that country. Those included pregnant, Tshegofatso Pule who was found hanging from a tree, Naledi Phangindawo, who was stabbed, and Sanele Mfaba whose body was later found in a Soweto township. South African campaigners note that in fact violence against women shot up from the moment the lockdowns began. The police force’s gender-based violence hotline received 2,300 calls in the first five days – nearly three times the rate prior to lockdown. Even so, Ramaphosa’s remarks were significant as this represented one of the few instances when an African Head of State has spoken out forcefully on the issue. Community-based Prevention and Education Are Key While some actions are being taken to improve Africa’s response to gender-based violence including building police and judiciary systems that understand their roles and can prosecute cases of gender-based violence, more needs to be done about awareness-raising and education that can prevent crimes from ever occurring, stressed Byanyima. “In my view, we are weakest on prevention. You need aggressive campaigns discouraging violent behaviors of boys and men, especially the way they see their masculinity and how they exercise it. That discouragement still needs to happen,” Byanyima said. Presently, this duty is largely left to civil societies and women organisations, but Byanyima noted that it is the business of the government to invest in continual campaigning in communities to change how relationships can be managed without violence. Winnie Byanyima “This is about men’s behavior – the way men are raised and see themselves as men. Tackling toxic masculinity is something that is not well invested in,” she said. Another necessary action to tackle the silent pandemic is to empower girls and women in African societies. Citing data from HIV, the UNAIDS Executive Director noted that an African girl’s vulnerability to HIV, sexual violence, unintended pregnancy and early marriage reduce by up to 50% if she is able to complete high school. But while African leaders have ratified universal basic education requiring every child to get at least primary education, two-thirds of children in Africa do not have access to secondary education. “The time for secondary education has come. We fought for universal primary education in Beijing and within ten years we have achieved it. Now we need to draw the line and say every government worth its name must put its kids, boys and girls, through high school. Not only for the knowledge economy but also for the safety and empowerment of girls and fighting gender-based violence,” Byanyima said. Story of Success: Experts Laud Rwanda’s One Stop Center For Sexual Violence Bineta Diop, African Union’s Special Envoy on Women Peace & Security, recommended African governments adopting Rwanda’s one-stop center for sexual violence. Located within the Kacyiru Police Hospital, the Isange One Stop Centre, the Isange One Stop Center has become a hub for gender-based violence survivors. At the center, survivors can access all the required services in one place and for free. The center is operated by the country’s Gender and Family Promotion, of Health, and Justice ministries in addition to the Rwanda National Police. Bineta Diop The initiative that started in 2009 as a pilot has since been expanded across the country. Rwanda now has a One Stop Centre in every district. Every day, up to 12 survivors are received at the center. “28% are survivors of intimate partner violence and 78 percent are survivors of sexual violence. Of the 78% of survivors who have been sexually assaulted, 16% are younger than 5 years,” said Daniel Nyamwasa, Commissioner of Police and Chief Infectologist Consultant at the hospital. Diop also encouraged African governments to acquire DNA testing capabilities to provide evidence that could be used to prosecute cases of rape and other gender-based violence against women and girls. Enlisting More Women in Police and Judiciary Another solution is the enlistment of more women in the police and judiciary systems across the continent which Diop said will encourage more women to approach the legal system to file complaints. She also called for the engagement of Africa’s traditional leaders. “If you want to break the patriarchal system, you have to engage the traditional system,” Diop said. However, as the number of confirmed cases of COVID-19 in Africa is increasing, African governments are also focusing on how to quickly and safely reopen their economies to minimize the impact of the pandemic. This current reality threatens the materialization of recommendations giving more attention to combating gender-based violence. But Ramaphosa, for one, has said this does not have to be the case. In his comments last week, he stressed that action can and should be taken to combat violence, despite the numerous familiar and peculiar challenges that countries across the continent are facing: “For public faith in the criminal justice system to be maintained, gender-based violence needs to be treated with the urgency it deserves by our communities working together with our police.” Cyril Ramaphosa, President of South Africa Image Credits: Paul Adepoju, Twitter: Youth Alive Foundation, UN Women. Massive Mobilization Of US $31.3 Billion Required For COVID-19 Diagnostics, Drugs & Vaccines Accelerator 26/06/2020 Grace Ren Central Laboratory at the Academician Nikoloz Kipshidze University Clinic, Tbilisi, Georgia, receives laboratory equipment for COVID-19 diagnosis. The World Health Organization aims to raise a whopping US $31.3 billion to fund the ambitious goals of the Access to COVID-19 Tools (ACT) Accelerator; a multi-stakeholder initiative that aims to develop and deploy diagnostics, drugs, and vaccines to control the virus. But so far, only $US 3.4 billion has been pledged towards the initial goals. And US $13.7 billion is ‘urgently needed’ in order to cover immediate needs, according to an investment case released by WHO on Friday. “Though these numbers sound big, they are not. If we spend billions now, we will avoid spending trillions later. The time to act is now, and the way to act is together,” said Gavi Board Chair Ngozi Okonjo-Iweala. The funding will go toward: Scaling up development and delivery of 500 million diagnostic tests to low- and middle-income countries (LMICS) by mid-2021 Delivering 245 million courses of treatments to LMICs by mid-2021, Delivering 2 billion vaccine doses, of which 50% will go to LMICs by the end of 2021. “It’s clear that because all people are at risk of COVID-19, all people should have access to all the tools to prevent, detect and treated, not only those who can afford to pay for them,” said World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus at a Friday press briefing. “We have made the principle of equitable access a simple thing to say, but a complicated thing to implement.” Dr Tedros at the 26 June press briefing More than 9 million people have been infected, and nearly half a million have so far lost their lives to the virus. The investment required in the Accelerator is less than a tenth of the loss the global economy is facing every month due to the pandemic, according to International Monetary Fund estimates. “The cost of inaction now is quite important to take into consideration,” said Philippe Duneton, executive director of UNITAID, working with the Wellcome Trust on the therapeutics pillar of the project. A good portion of the immediate investments will go towards preparing markets to absorb new COVID-19 technologies, setting up demand, manufacturing, and country capacity to roll out any new diagnostics, vaccines, or drugs. Four Investment Pillars Require Urgent Funding The ACT Accelerator operates under four main pillars – diagnostics, therapeutics, vaccines, and the health systems connector. The diagnostics pillar, co-led by FIND and the Global Fund to Fight AIDS, Tuberculosis, and Malaria, aims to avoid 1.6 billion further infections by scaling up access to diagnostics. The pillar requires US $6 billion in the next year, but US $2 billion is urgently needed to begin deploying tests now. Ultimately, 10,000 healthcare workers will be needed. “The real strategy towards containing the epidemic is through testing, tracing, isolation; and the starting point for that is a very rapid rollout of very large numbers of tests,” said Peter Sands, executive director of the Global Fund. “To underscore the urgency for many lower middle income countries, lockdown is not sustainable. Households don’t have the wherewithal to continue without working, and governments don’t have the ability to compensate for lost income, coupled with the fact that clinical care facilities are extremely limited.” The therapeutics pillar will focus on accelerating the development and deployment of effective treatments. While no drugs have yet been tapped, the pillar aims to provide 250 million courses of treatment to LMICS in the next 12 months. Some US$11.6 billion is needed in the next year, while US $3.8 billion is needed immediately. “Of course, as soon as we have a medicine, the situation at the country level will also be a challenge,” said Duneton. “The access to oxygen, for example, is not the same in all countries.” But “the only way to prevent further transmission [of the virus] and to break that cycle, would be to have an effective and safe vaccine available to people,” said WHO Chief Scientist Soumya Swaminathan. Soumya Swaminathan speaks at the 26 June ACT Accelerator press briefing The vaccines pillar has an ambitious goal of delivering 2 billion doses by the end of 2021. Seven candidates are currently in clinical trials, but none have yet received regulatory approval. So far, the fastest vaccine to move from lab bench to approval for human use was the Ebola vaccine – which took five years to develop. “In general, it takes 8 to 10 years for a vaccine to move from when the research begins to when it gets into people. We want to shorten that timeline as short as possible – 12 months, 18 months maximum,” said Swaminathan. “That would be unprecedented, and can only happen through global collaboration.” The Coalition for Epidemic Preparedness Innovation (CEPI), and Gavi, the Vaccine Alliance, will lead the vaccines pillar alongside WHO, which will provide oversight of regulation, policy and allocation. Some US $18.1 billion is required to safely deliver the vaccine to people in need. Gavi, through an advanced market agreement under its COVAX Facility, aims to pool purchasing power from nations of all income levels to secure low vaccine prices. Some 950 million doses must be procured by self-financing, upper-middle and high income countries, in addition to the 2 billion doses set aside for lower income countries. A final pillar, the health systems connector, aims to strengthen the infrastructure and community networks required to deliver tools to people in need. Led by the World Bank, and the Global Fund, the pillar aims to build lab capacity, train staff to safely manage COVID-19, and to use new tools as they are deployed. Image Credits: Flickr: IAEA Imagebank/Natalia Khurtsidze, PR Manager of the Clinic. Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts This site uses cookies to help give you the best experience on our website. Cookies enable us to collect information that helps us personalise your experience and improve the functionality and performance of our site. By continuing to read our website, we assume you agree to this, otherwise you can adjust your browser settings. Please read our cookie and Privacy Policy. Our Cookies and Privacy Policy Loading Comments... You must be logged in to post a comment.
World Health Organization Will Send Scoping Mission To China To Investigate COVID-19 Origins 30/06/2020 Editorial team Dr Tedros at a June 2020 press briefing The World Health Organization will be sending a mission to China on 6 July to investigate the origins of SARS-CoV-2, the virus that causes COVID-19, WHO Director-General Dr Tedros Adhanom Ghebreyesus subtly announced at a Monday press briefing. The mission aims to fulfill decisions made in a unanimously passed World Health Assembly resolution in late May, which requested WHO work with World Organisation for Animal Health (OIE), the Food and Agriculture Organization of the United Nations (FAO) and countries to “identify the zoonotic source of the virus and the route of introduction to the human population, including the possible role of intermediate hosts.” “We will send a team next week to China to prepare this and hopefully it will lead to a better understanding of how the virus started and what we can do in the future to prepare for it,” said Dr Tedros on Monday, in response to a query from a Brussel Times journalist following-up on the status of actions outlined in the resolution. Two WHO experts will be sent on the initial scoping mission; an expert in animal health and an epidemiology expert with a background in investigating epidemics in the field, WHO Health Emergencies Executive Director Mike Ryan added on Wednesday. While researchers largely believe that the virus jumped the animal-human barrier at a wet market in Wuhan, China, some have posited that the virus may have escaped from a high level virology lab within miles of the first cluster of confirmed cases. The quiet announcement underlines the political tensions surrounding the investigation of origins of the virus, with WHO caught in an ongoing feud between China and the United States. United States President Donald Trump has repeatedly slammed the World Health Organization for supposedly catering to China’s favor and delaying global responses to the pandemic, despite once praising the WHO and China response before COVID-19 reached US shores. Trump has made WHO’s supposed deference to China the main point of contention for withdrawing US support from the agency, even as the US continues to face an accelerating pandemic at home, reporting the highest numbers of new cases and hospitalizations daily. But WHO has little authority over Member States’ actions, and must balance criticising pandemic responses with retaining access to data and knowledge. The first WHO mission to China was delicately arranged at the end of January, after Chinese authorities locked down the Wuhan, a city of 11 million people, following a spike in cases due to a delayed response in early January. Since largely coming out of lockdown in May, the outbreak in China has been tightly controlled. However, new clusters of cases in Jilin province, Wuhan city, and the capital of Beijing have sparked great unease and second rounds of lockdowns. Swelling Indian National Opposition As Modi Plans To Expand Coal Mining 30/06/2020 Jyoti Pande Lavakare Coal miners in India’s resource-rich Meghalaya State. A government tribunal banned coal mining in the region in 2015. New Delhi, India – Prime Minister Narendra’s Modi’s ambitious plan to use coal to power India’s economic revival after his government’s strict lockdowns flattened the wrong curve, bringing economic growth to a halt even as the infection epidemic curve continued to rise, seems to have run into significant opposition from unexpected quarters. Since the launch of his plan earlier this month, state after Indian state has expressed disagreement with the Centre’s plan to commercially auction coal mines to the private sector, including international players. The latest to join the clamour of opposition by the states of Chhattisgarh, Jharkhand and Maharashtra, where more than half of the 41 mines are located – is the politically powerful chief minister of West Bengal, Mamata Banerjee. Indian environmentalists have also decried a seemingly desperate announcement by the government to auction off 41 Indian coal mines, opening a largely government-controlled sector up to all private investment for the first time ever – and thus greatly accelerating domestic coal production. Coal mining by Eastern Coalfields Ltd., the company that operates national coalfields in Jharkhand and West Bengal states. As of now, two government-owned mines produce over 90 % of India’s coal. Indian coal, known for its high fly ash content– and therefore pollution emissions – currently supplies about 80% of the country’s total coal needs, while the rest is imported. Coal, in turn, powers about 44% of the total energy needs, compared to oil (24%) and biomass (22%) – though the latter is often burned in highly polluting domestic cookstoves emitting climate-changing black carbon particles. Also, hydroelectric power supplies 1.4% of the economy, leaving solar and wind to supply only around 0.8% of the country’s total power needs. When it comes to electricity generation, the picture is just a little bit better. Coal powers 73% of electricity in India, while solar and wind fuel around 8% and hydro around 12% respectively, said Karthik Ganesan, Research Fellow, Council on Energy, Environment and Water. Clean air campaigners had hoped that the glimpse of blue skies, clean water bodies and nature restoring itself in the limbo provided by the lockdown of all growth engines would encourage decision-makers to choose a growth recovery path that had low environmental impact. Health and environmentalist activists had expected the government to look at growth recovery more holistically, which meant including developmental indicators like health, education and quality of life – in the spirit of the recent WHO manifesto for a healthy green recovery, which calls to put a stop to fossil fuel subsidies using taxpayer money. Unfortunately, India seems to be ignoring all of the recent health and climate warming signals – the latest being the swarms of locusts that are invading parts of the country as it focuses on coal to fuel its recovery. Ostensibly, Modi’s rationale is that the move will help make India energy self-sufficient and quickly claw back the robust growth curve that had begun to fall off even before the COVID-19 pandemic struck the country. However, investing heavily in coal also serves some of his key political alliances, some of whom – like the Adani Group – are also planning to export massive new coal reserves from Australia to India. Opposition to Modi’s Move Growing in India Existing, new, and planned coal mines in India (Credit: R. Pearce, T. Prater, S. Evans/Carbon Brief) Despite the pressing economic challenges that India admittedly does face, some leading Indian politicians are beginning to speak out in opposition to the coal mining plans – bringing this sector back into centre stage for the first time since “Coalgate,’ a coal scam that tainted the previous government a decade ago. Jharkhand state has already approached the Supreme Court challenging this auction, followed by Chhattisgarh and Maharashtra writing to the central environment minister Prakash Javadekar objecting to the auction. The latest to join the rising voice of critics is the feisty Chief Minister of West Bengal (and Modi’s bete noire) Mamata Banerjee, known for her blunt statements and ability to stand up to the central government. Last Thursday, Ms Banerjee wrote to Modi on Thursday, asking him to reconsider the decision, saying that “this policy can neither bring foreign direct investments not can it bring technologies or know-how which we are unable to access today,” and noting that global investors are more interested in renewable energy projects rather than coal, which offers low returns. None of the 41 mines coming up for auction are located in her state. Her objection is in principle and adds political weight to the growing opposition. States like Jharkhand, Maharashtra and Chhattisgarh, where more than half the mines coming up for auction are located, have already voiced opposition to this decision, citing huge environmental and social costs: “Riding on coal could spur the economy in the very short term and an extremely high ecological and social cost”, said Niraj Bhatt, Researcher in Environment and Climate Action for the Chennai-based Citizen consumer and civic Action Group (CAG), who works in the coal sector. The long term costs of promoting coal are disastrous, even in the government’s very first Climate Assessment report. The report warns of a four-fold increase in heat wave frequency and a doubling in the length of heat waves in India by 2100. “It is inexplicable why the government is prioritizing coal for fast track revival of the Indian economy since the pandemic”, given the knowledge that’s available, added Bhatt. Many local communities also are opposed to the government’s decision to privatize coal mining, fearing that this will degrade the environment. Most of the 41 coal mines in auction are in pristine forest areas. Even at the village-level, several panchayats (local governance bodies that make the fundamental building blocks of governance) have asked Modi to withdraw this auction. “Nine village panchayats from Hasdeo Arand forest region have written to the Prime-minister asking for withdrawing the auction of five coal blocks in the region for commercial mining as it would impact their livelihood and culture,” said Avinash Kumar Chanchal, a grassroots climate activist who has written on the degradation of the Singrauli coal belt and displacement of local communities. UN Secretary General Also Decries Coal Plans There is no good reason for any country to include coal in their #COVID19 recovery plans. This is the time to invest in energy sources that don’t pollute, generate decent jobs and save money. — António Guterres (@antonioguterres) June 29, 2020 United Nations Secretary-General Antonio Guterres has said there is no reason for any country to include coal in the COVID-19 recovery plans. Instead, investments should be made towards non-polluting energy sources; and opposition to a “black, coal-powered recovery” has grown in India. It isn’t clear whether this diplomatic rap on the knuckles and growing opposition will succeed in stopping the government in its polluting tracks, especially if Modi’s public statements on privatising coal mines – framed in his signature style with the bells and whistles of patriotism and nationalism for “atma-nirbharta” or self-reliance – are anything to go by. Desperate for funds and eager to kickstart a sluggish economy threatening to fall into a recession, the central government seems prepared to roadroll its way through. Its desperation stems from predictions of the most severe recession in the past the four decades – The International Monetary Fund has predicted a global annual downturn of 4.5%, though ratings firm India Ratings has predicted the Indian economy to contract by 5.3% this year. Renewable Energy Offers Untapped Potential Analysts say that the government is gambling on coal mining to generate over a million of jobs, as it is labour-intensive and rural communities are increasingly desperate for jobs following mass reverse migration since the pandemic began. Additionally, there is built-in momentum for coal power development, since it is already well-established and subsidized by the government – whereas renewables are a new game altogether, and energy storage issues still remain unresolved – as some critics claim. Activists and economists counter that government forces have ignored the potential of alternative energy sources at the current juncture: “There is huge potential to generate new jobs in renewable energy. Some analyses have estimated that more than one million jobs can be created by the renewable sector by 2022 if India can achieve its ambitious renewable target of 160GW,” said Chanchal. “The illusion of low cost energy from coal has been debunked globally. Socially, environmentally and economically, coal is very costly. It’s bad economic policy to invest in high cost options when cheaper alternatives exist today,” added Laveesh Bhandari, an economist turned environmental advocate, who works at the intersection of sustainable employment and climate change. “It’s almost as if we’re moving backwards. The whole world is moving away from coal. Several studies in India have shown the adverse effects of pollution caused by coal mining on the health of communities living within coal mining areas, especially on the respiratory system.” Even before pandemic, deaths from air pollution have been a major issue in India. In 2016, household pollution led to over a million deaths in India, according to the WHO’s Global Health Observatory; and in 2012, ambient air pollution claimed 620 000 Indian lives, with a shocking toll of over 20 million disability-adjusted life years (DALY), according to the WHO’s global assessment of exposure and burden of disease. However, now there is also the added factor of COVID-19, in which case chronic heavy exposures to air pollution will also increase vulnerability from the virus as well as mortality, said grassroots environmentalist and writer Rinchin, who goes by one name only and works with adivasis in Chhattisgarh. “Whether the Centre can still go ahead is a legal issue, but it will be bad form to go against the position of state governments. India is a federation, and something like mining that impacts not only the environment, but society itself therefore needs to be overseen, regulated and controlled by the state”, added Bhandari. India’s Ambition – Regional Energy Supplier? Coal mining in India While Modi is framing the coal auction as a move towards greater national self-reliance, the story is in fact more complex. His plan may involve ambitions to become a regional energy-producing power. It also aligns national policy with the commercial interests of close political allies – such as Indian billionaire Gautam Adani, and head of the powerful Adani group. Adani is leading the Carmichael project – a massive mining initiative to export Australian coal to India. Just last year, the Australia’s government gave the go-ahead for the project, the world’s largest open pit mine, overriding stiff opposition from Australian environmentalists. Adani plans to use the Australian coal for a new $2 billion power plant that his company is building in India, which will also produce electricity for sale in neighboring Bangladesh. Ever since Modi was the chief minister of the western state of Gujarat – Adani’s birthplace and home region – Adani and Modi were known to have close links. “The story of Adani and its Australian project illustrates why the world keeps burning coal despite its profound danger — and despite falling prices for options like natural gas, wind and solar,” the New York Times said last year. In fact, India’s coal ambitions under Modi will not just undermine existing efforts to limit climate change and worsen air and water pollution within the country, they are also likely to compromise the entire region, setting an undesirable example of fossil fuel dependency in neighbouring countries. Little Matter of Coal Gasification Air pollution in Delhi, India Then, there is that little matter of Modi’s plans for coal gasification – a technology that could further reduce India’s dependence on imports, but at an even higher level of carbon emissions – as well as potential water contamination from coal pollutants. The government’s current plan is to promote “syngas” -a substitute for imported liquified natural gas produced by coal gasification – to produce urea in fertilizer. This will not only help reduce liquified natural gas (LNG) imports but also urea imports, leading to a lower import bill and greater self-reliance. According to the Ministry of Chemicals and Fertilisers, urea is currently produced using pooled natural gas, which consists of both domestic natural gas and imported LNG. The usage of locally available coal for making fertilisers would help reduce the import of LNG, the Ministry has said. “The big question is when we have cleaner, cheaper, and sustainable renewable energy sources why do we want to invest in dirty and polluting technologies and energy sources? India is already facing a climate crisis,” said Chanchal. While natural gas is considered a lower climate emitter than coal, syngas is just the opposite. A study by Duke University found that syngas produced by coal gasification emits seven times more greenhouse gases than natural gas, making it a huge contributor to climate change. “It contaminates both surface water and groundwater, and also emits greenhouse gases. If renewable energy is available and becoming cheaper day by day, then why does the government want to start commercial mining to create coal based energy.” “Right now, the government is speaking like a climate leader but acting like a climate laggard by betting high on coal and promoting it,” added Bhatt. Mining Could Also Increase Dangerous Human-Wildlife Conflicts Dog sleeps on a bed of coal in Asansol, India Along with the climate and air pollution risks, activists have also warned that expanding mining operations in the areas up for auction could trigger increased human-wildlife conflict. “Among the 41 coal mines up for auction, most are situated in the dense forest of central India,” said Chanchal. “These forests are home to large populations of elephants and other wildlife. Some proposed coal blocks are also near tiger reserves, like in Maharashtra. “Along with vast forest destruction, coal mines will also increase the human-wildlife conflict. The implications are countless from the displacement of adivasis, to the violation of the Forest Rights Act, to public health,” said Chanchal, who has also written The Singrauli Files about the degradation of that region. “We have already seen how coal mines destroyed the rich biodiversity of places like Singrauli, Korba, and in other coal belts where thousands of adivasi and local communities were displaced, their forests, livelihood and human rights violated. They are already living with serious health crises,” he added. In a parallel move, Modi’s Ministry of Environment and Forestry also has launched an initiative to dilute existing environmental impact assessment norms for the creation of industries in pristine areas, including, but not limited to coal – a move that has been staunchly opposed by environmentalists – but action on that has been postponed by the courts until August. Modi Still Likely to Face Bureaucratic Challenges India’s Prime Minister Narendra Modi Despite the burgeoning opposition, Modi remains determined and eager to develop the private coal sector. Against the wave of new criticism he has remained silent – a typical tactic of response. However, India’s federal structure of governance may still slow down the realization of his vision considerably – giving environmentalist valuable time to mount a more organized local and global opposition. In the Indian governance model, the central government is expected to execute policy in consultation with state governments on a consensus model. More importantly, if the land is pristine forest land, as in this case, local self-governance laws and the FRA will make it challenging for it to move ahead with coal block allocation in such areas, which may still stave off this path to a quicker, but blacker, revival. “Land is a state subject, the Centre cannot go ahead without support from the states,” said Bhatt. “The implementation of the Forest Rights Act is also very crucial in these regions. The government which is promoting ‘atma-nirbhar Bharat’ should consider these concerns of local communities and take appropriate action to strengthen the self-governance of the gram sabha,” adds Chanchal. Image Credits: Environmental Change and Security Program, Flickr: Partha Sarathi Sahana, R. Pearce, T. Prater, S. Evans/Carbon Brief, Environmental Change and Security Program, Wikimedia Commons: Prami.ap90, Flickr: Partha Sarathi Sahana, Mike Bloomberg. World Surpasses 500,000 COVID-19 Deaths; Medicines Access Experts Challenge US $2340 Per Remdesivir Treatment Course Price Set By Gilead For Developed Countries 29/06/2020 Grace Ren Vial of remdesivir A six-vial five-day course of remdesivir – a promising COVID-19 treatment – will be priced at US $2340, or $390 per vial for developed countries, Gilead Sciences Chief Executive Officer Daniel O’Day wrote in an open letter on Monday. “Earlier hospital discharge [thanks to treatment by remdesivir] would result in hospital savings of approximately $12,000 per patient,” wrote O’Day. “We have decided to price remdesivir well below this value.” But the price is still high compared to the cost of manufacturing, according to medicines access experts, who say that remdesivir could be produced for below a dollar a day. Private insurers in the United States will pay US $3,120 for a five-day course, or $520 per vial. Out-of-pocket payments will be determined by individuals’ coverage plans. In 127 developing countries, Gilead has allowed generics companies to manufacture the drug, pricing a five-day course at about US $600. Cost of production for the drug can be as low as US $0.93 per day, according to a paper by Dr Andrew Hill, a senior visiting research fellow at the University of Liverpool, and his colleagues. “Gilead will turn a nice profit with its set price. Especially considering that the company has benefitted from significant government financing for the development of the drug; which apparently has not been discounted,” Ellen t’Hoen, director of Medicines, Law and Policy, told Health Policy Watch. electron microscope photo of SARS-CoV-2, the virus that causes COVID-19 “Based on publicly available data, it has been estimated that taxpayers have contributed at least $70.5 million to develop this drug,” Jessica Burry, a pharmacist at Médecins Sans Frontières Access Campaign, said to Health Policy Watch. “Additionally, contributions were made by various health organisations, including MSF, which supported clinical trials with this drug for Ebola in 2019. Patients themselves have also contributed by their participation in the trials. “Public funding and resources have contributed to the drug’s further development for COVID-19, and taxpayers will now end up essentially “paying twice” to access this treatment,” added Burry. The company could turn a US $2.3 billion profit on the “blockbuster” drug this year alone, according to a blog by Ellen t’Hoen. “This does put pharma’s lofty promises of not profiteering during the pandemic into perspective. I hope governments begin to realise that the important investments they make for the development of drugs and vaccines to respond to COVID-19 need to come with strings attached to ensure fair pricing and global access,” she said. COVID-19 Cases Surge Past 10,000,000, Deaths Reach Half A Million Meanwhile, the World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus warned on Monday that “the worst was yet to come.” Dr Tedros spoke at a press conference just as the number of deaths from COVID-19 topped half a million, and cumulative cases surged past 10,000,000. The US and Brazil continue to report around 40,000 new cases day. In the state of Texas, which saw one of the fastest rising daily case counts after reopening, hospitals in the capital city of Houston are nearing ICU capacity. Even as Vice President Mike Pence lauded the state’s reopening at a press briefing Monday, Texas Governor Greg Abbot warned that the epidemic had taken a “very swift and very dangerous turn.” Abbot shut down bars and clubs again across the state in an attempt to limit the fast-spreading virus. Remdesivir Pricing Announcement Comes On Heels Of EMA Conditional Marketing Authorization Endorsement Remdesivir, a failed Ebola antiviral, is one of the frontrunner drugs for treating COVID-19. It was shown to significantly reduce the length of hospital stay from an average of 11 days to an average of 15 days in a recent trial funded by the US National Institute of Allergies and Infectious Diseases (NIAID). However, the NIAID trial results were based on a 10-day treatment course, rather than the 5-day course that Gilead has currently priced. And studies have so far not reported any effects in reducing mortality. Still, the European Medicines Agency recently renewed their endorsement of the drug, recommending the agency give remdesivir conditional marketing authorization – a stamp of approval that many European Union countries use as guidance for approving drugs for diseases with few cures. Remdesivir is currently approved for use in Japan for COVID-19 patients. The United States Food and Drug Administration has approved the treatment for ’emergency’ use, just two days after the NIAID trial results were announced. The announcement comes just as Gilead’s promise to donate remdesivir until the end of June 2020 hits its deadline. US Health and Human Services Secretary Alex Azar announced Monday that the government had secured another half a million treatment courses of remdesivir for U.S. hospitals through September, according to an interview with “Good Morning America.” Health and Human Services will be paying the US $390 per vial price, and be responsible for allocating Gilead’s supply of remdesivir, according to O’Day’s letter. But some middle income countries that are hoping to secure their own supply of remdesivir may be out of luck, according to Burry. “Gilead has entered into license agreements with several generic companies in India, Pakistan and Egypt. The license, however, excludes nearly half of the world’s population, including most South American countries and a number of middle-income countries, such as Brazil, Russia and China,” said Burry. “Since the corporation has barely been able to supply enough quantities of this drug even to the US, it is highly unlikely that it will be able to meet the demands of all the other countries that have not been included in this license.” Brazil Signs Contract To Produce AstraZeneca & Oxford COVID-19 Vaccine Candidate; China Approves CanSino Vaccine Candidate For Military Use In a parallel development, Brazil on Saturday signed a contract with AstraZeneca and Oxford to manufacture an experimental COVID-19 vaccine candidate. Meanwhile, China approved the CanSino COVID-19 vaccine candidate for military use on Thursday. Local vaccine manufacturer Fiocruz will be producing up to 100 million doses of the vaccine overall, Brazilian authorities announced at a press briefing. The country will pay $127 million to receive material to produce 30.4 million doses in two batches in December and January, with the rest to come later. China’s Central Military Commission approved the CanSino vaccine for use by the military for a period of one year beginning 25 June 2020, according to a CanSino filing. The Academy of Military Sciences had jointly developed the vaccine candidate with CanSino. Results from a small, non-randomized trial released in May found that about 75% of people who received high doses of the CanSino vaccine candidate developed antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, after 28 days. However, the developers highlight that large, randomized control trials must be done in order to determine if the vaccine truly protects against infection by the virus. And other researchers pointed to old concerns with the Ad5 vector used in the CanSino vaccine. Previous Ad5-vectored vaccine candidates for HIV were dropped after early trials showed the experimental vaccine inadvertently increased the risk of HIV infection. This story was updated 30 June 2020. Image Credits: European Medicines Agency, NIAID, World Health Organization, NIAID. Gender-Based Violence – The “Shadow Pandemic” Of COVID-19 26/06/2020 Paul Adepoju While a face mask could provide some protection against COVID-19, the lives of many women in Africa, and elsewhere, are at the mercy of their abusers. (Photo Credit: Paul Adepoju) Ibadan, Nigeria – Twenty-two year-old Uwaila Vera Omozuwa, freshly admitted to university, had retreated to study in a church in the city of Benin, Nigeria during lockdown, when she was raped and killed on May 30. The following day, 18-year-old Barakat Bello was reportedly raped and killed in Oyo state. 29-year-old Azeezat Shomuyiwa and 21-year-old Grace Oshiagwu also suffered similar fates just days and few streets apart. In late March 2020, a video from Ghana surfaced on social media showing a boyfriend assaulting his girlfriend. As the COVID-19 pandemic continues to expand globally, African countries as well as other nations worldwide are also dealing with another related pandemic – that of gender-based violence. The stress triggered by COVID-19 lockdowns and economic uncertainty is exacerbating violent assaults, according to experts speaking at a panel last week hosted by the WHO Regional Office for Africa. Effectively, the pandemic has forced many women who are in abusive relationships to remain shut up at home with their abusers, further escalating their risks, they said. Social media responses condemning the gruesome murder and rape of Vera Uwaila Omozuwa. (Photo Credit: Youth Alive Foundation ) A “Shadow Pandemic” Gender-based violence is a “shadow pandemic” to COVID-19 said UN Women’s Executive Director, Phumzile Mlambo-Ngcuka. She noted that in Africa as well as elsewhere in the world, domestic violence hotlines and shelters are reporting rising calls for help. “Confinement is fostering the tension and strain created by security, health, and money worries. And it is increasing isolation for women with violent partners, separating them from the people and resources that can best help them,” Mlambo-Ngcuka said in a statement on violence against women and girls. “It’s a perfect storm for controlling, violent behaviour behind closed doors. And in parallel, as health systems are stretching to breaking point, domestic violence shelters are also reaching capacity, a service deficit made worse when centres are repurposed for additional COVID-response.” Africa has struggled with social attitudes sanctioning violent attacks on women, well before the pandemic began. For instance, in 2017, researchers at the University of Ghana reported that men who were in consensual unions or customary marriages remained in favour of wife beating. Police attitudes are often lax as well. Following Uwaila’s rape and murder in Benin, Nigeria, for instance, the local police initially demanded a “mobilization money” from the family to open an investigation, according to the victim’s sister, who finally led a protest to the Edo State police headquarters to trigger action – which she videotaped on Instagram. Now, in the period of COVID-19, for every 3 months lockdowns are imposed or continue, an additional 15 million extra cases of gender-based violence could be recorded worldwide, states a new report, COVID-19: A Gender Lens, by the UN Population Fund (UNFPA). And six months of lockdown could result in additional 31 million cases of gender-based violence in the world. Photo Credit: UN Women While the most extreme outcome, gender-based violence is not the only way women are suffering from lockdown restrictions, noted Dr. Natalia Kanem, UNFPA Executive Director while unveiling a new analysis by UNFPA and partners. “Millions more women and girls now risk losing the ability to plan their families and protect their bodies and their health,” she said, noting that women often cannot get to health services for basic care. “Women’s reproductive health and rights must be safeguarded at all costs. The services must continue; the supplies must be delivered; and the vulnerable must be protected and supported.” Fighting the Shadow Pandemic In Africa, political leaders have generally been reluctant to make themselves the face of campaigns against gender-based violence, the panel participants observed, recommending that Africa’s political leaders need to start speaking up now. “African leaders need to declare this situation as another pandemic and appeal to people, men, society, and those who set norms. African leaders need to speak up and recognise this is happening,” said Dr Matshidiso Moeti, WHO African Regional Director while speaking on the panel. Governments also need to make gender-violence prevention initiatives integral to economic and healthcare programmes dealing with COVID-19, she said. Matshidiso Moeti Specifically, she mentioned that police officers and health workers in African countries need to be made aware of the roles they are supposed to play in prevention of gender-based violence. For countries that are still in the dark over what to do, she noted that the government can work with men and women groups to improve the level of public education, provision of call numbers to report cases of abuse, and establishment of shelters to provide help and services to victims. “These can be part of the socio-economic response to the pandemic,” Moeti added. While most African countries now have legislation against gender-based violence, political leadership is still missing, agreed Winnie Byanyima, Executive Director of the Joint United Nations Programme on HIV/AIDS (UNAIDS). “I so rarely hear a male African leader speaking and leading on this issue. Most African leaders leave it to others, yet it is a pandemic – a silent one too,” Byanyima said. For Africa to advance in tackling gender-based violence, African leaders must be saddled with the responsibility of providing political leadership, she said. One leader that has spoken up recently was South African President Cyril Ramaphosa, a political powerful voice, as he is also the head of the African Union. Speaking to the media last week, he blamed the reopening of liquor stores as lockdown measures eased for a spate of attacks on women in that country. Those included pregnant, Tshegofatso Pule who was found hanging from a tree, Naledi Phangindawo, who was stabbed, and Sanele Mfaba whose body was later found in a Soweto township. South African campaigners note that in fact violence against women shot up from the moment the lockdowns began. The police force’s gender-based violence hotline received 2,300 calls in the first five days – nearly three times the rate prior to lockdown. Even so, Ramaphosa’s remarks were significant as this represented one of the few instances when an African Head of State has spoken out forcefully on the issue. Community-based Prevention and Education Are Key While some actions are being taken to improve Africa’s response to gender-based violence including building police and judiciary systems that understand their roles and can prosecute cases of gender-based violence, more needs to be done about awareness-raising and education that can prevent crimes from ever occurring, stressed Byanyima. “In my view, we are weakest on prevention. You need aggressive campaigns discouraging violent behaviors of boys and men, especially the way they see their masculinity and how they exercise it. That discouragement still needs to happen,” Byanyima said. Presently, this duty is largely left to civil societies and women organisations, but Byanyima noted that it is the business of the government to invest in continual campaigning in communities to change how relationships can be managed without violence. Winnie Byanyima “This is about men’s behavior – the way men are raised and see themselves as men. Tackling toxic masculinity is something that is not well invested in,” she said. Another necessary action to tackle the silent pandemic is to empower girls and women in African societies. Citing data from HIV, the UNAIDS Executive Director noted that an African girl’s vulnerability to HIV, sexual violence, unintended pregnancy and early marriage reduce by up to 50% if she is able to complete high school. But while African leaders have ratified universal basic education requiring every child to get at least primary education, two-thirds of children in Africa do not have access to secondary education. “The time for secondary education has come. We fought for universal primary education in Beijing and within ten years we have achieved it. Now we need to draw the line and say every government worth its name must put its kids, boys and girls, through high school. Not only for the knowledge economy but also for the safety and empowerment of girls and fighting gender-based violence,” Byanyima said. Story of Success: Experts Laud Rwanda’s One Stop Center For Sexual Violence Bineta Diop, African Union’s Special Envoy on Women Peace & Security, recommended African governments adopting Rwanda’s one-stop center for sexual violence. Located within the Kacyiru Police Hospital, the Isange One Stop Centre, the Isange One Stop Center has become a hub for gender-based violence survivors. At the center, survivors can access all the required services in one place and for free. The center is operated by the country’s Gender and Family Promotion, of Health, and Justice ministries in addition to the Rwanda National Police. Bineta Diop The initiative that started in 2009 as a pilot has since been expanded across the country. Rwanda now has a One Stop Centre in every district. Every day, up to 12 survivors are received at the center. “28% are survivors of intimate partner violence and 78 percent are survivors of sexual violence. Of the 78% of survivors who have been sexually assaulted, 16% are younger than 5 years,” said Daniel Nyamwasa, Commissioner of Police and Chief Infectologist Consultant at the hospital. Diop also encouraged African governments to acquire DNA testing capabilities to provide evidence that could be used to prosecute cases of rape and other gender-based violence against women and girls. Enlisting More Women in Police and Judiciary Another solution is the enlistment of more women in the police and judiciary systems across the continent which Diop said will encourage more women to approach the legal system to file complaints. She also called for the engagement of Africa’s traditional leaders. “If you want to break the patriarchal system, you have to engage the traditional system,” Diop said. However, as the number of confirmed cases of COVID-19 in Africa is increasing, African governments are also focusing on how to quickly and safely reopen their economies to minimize the impact of the pandemic. This current reality threatens the materialization of recommendations giving more attention to combating gender-based violence. But Ramaphosa, for one, has said this does not have to be the case. In his comments last week, he stressed that action can and should be taken to combat violence, despite the numerous familiar and peculiar challenges that countries across the continent are facing: “For public faith in the criminal justice system to be maintained, gender-based violence needs to be treated with the urgency it deserves by our communities working together with our police.” Cyril Ramaphosa, President of South Africa Image Credits: Paul Adepoju, Twitter: Youth Alive Foundation, UN Women. Massive Mobilization Of US $31.3 Billion Required For COVID-19 Diagnostics, Drugs & Vaccines Accelerator 26/06/2020 Grace Ren Central Laboratory at the Academician Nikoloz Kipshidze University Clinic, Tbilisi, Georgia, receives laboratory equipment for COVID-19 diagnosis. The World Health Organization aims to raise a whopping US $31.3 billion to fund the ambitious goals of the Access to COVID-19 Tools (ACT) Accelerator; a multi-stakeholder initiative that aims to develop and deploy diagnostics, drugs, and vaccines to control the virus. But so far, only $US 3.4 billion has been pledged towards the initial goals. And US $13.7 billion is ‘urgently needed’ in order to cover immediate needs, according to an investment case released by WHO on Friday. “Though these numbers sound big, they are not. If we spend billions now, we will avoid spending trillions later. The time to act is now, and the way to act is together,” said Gavi Board Chair Ngozi Okonjo-Iweala. The funding will go toward: Scaling up development and delivery of 500 million diagnostic tests to low- and middle-income countries (LMICS) by mid-2021 Delivering 245 million courses of treatments to LMICs by mid-2021, Delivering 2 billion vaccine doses, of which 50% will go to LMICs by the end of 2021. “It’s clear that because all people are at risk of COVID-19, all people should have access to all the tools to prevent, detect and treated, not only those who can afford to pay for them,” said World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus at a Friday press briefing. “We have made the principle of equitable access a simple thing to say, but a complicated thing to implement.” Dr Tedros at the 26 June press briefing More than 9 million people have been infected, and nearly half a million have so far lost their lives to the virus. The investment required in the Accelerator is less than a tenth of the loss the global economy is facing every month due to the pandemic, according to International Monetary Fund estimates. “The cost of inaction now is quite important to take into consideration,” said Philippe Duneton, executive director of UNITAID, working with the Wellcome Trust on the therapeutics pillar of the project. A good portion of the immediate investments will go towards preparing markets to absorb new COVID-19 technologies, setting up demand, manufacturing, and country capacity to roll out any new diagnostics, vaccines, or drugs. Four Investment Pillars Require Urgent Funding The ACT Accelerator operates under four main pillars – diagnostics, therapeutics, vaccines, and the health systems connector. The diagnostics pillar, co-led by FIND and the Global Fund to Fight AIDS, Tuberculosis, and Malaria, aims to avoid 1.6 billion further infections by scaling up access to diagnostics. The pillar requires US $6 billion in the next year, but US $2 billion is urgently needed to begin deploying tests now. Ultimately, 10,000 healthcare workers will be needed. “The real strategy towards containing the epidemic is through testing, tracing, isolation; and the starting point for that is a very rapid rollout of very large numbers of tests,” said Peter Sands, executive director of the Global Fund. “To underscore the urgency for many lower middle income countries, lockdown is not sustainable. Households don’t have the wherewithal to continue without working, and governments don’t have the ability to compensate for lost income, coupled with the fact that clinical care facilities are extremely limited.” The therapeutics pillar will focus on accelerating the development and deployment of effective treatments. While no drugs have yet been tapped, the pillar aims to provide 250 million courses of treatment to LMICS in the next 12 months. Some US$11.6 billion is needed in the next year, while US $3.8 billion is needed immediately. “Of course, as soon as we have a medicine, the situation at the country level will also be a challenge,” said Duneton. “The access to oxygen, for example, is not the same in all countries.” But “the only way to prevent further transmission [of the virus] and to break that cycle, would be to have an effective and safe vaccine available to people,” said WHO Chief Scientist Soumya Swaminathan. Soumya Swaminathan speaks at the 26 June ACT Accelerator press briefing The vaccines pillar has an ambitious goal of delivering 2 billion doses by the end of 2021. Seven candidates are currently in clinical trials, but none have yet received regulatory approval. So far, the fastest vaccine to move from lab bench to approval for human use was the Ebola vaccine – which took five years to develop. “In general, it takes 8 to 10 years for a vaccine to move from when the research begins to when it gets into people. We want to shorten that timeline as short as possible – 12 months, 18 months maximum,” said Swaminathan. “That would be unprecedented, and can only happen through global collaboration.” The Coalition for Epidemic Preparedness Innovation (CEPI), and Gavi, the Vaccine Alliance, will lead the vaccines pillar alongside WHO, which will provide oversight of regulation, policy and allocation. Some US $18.1 billion is required to safely deliver the vaccine to people in need. Gavi, through an advanced market agreement under its COVAX Facility, aims to pool purchasing power from nations of all income levels to secure low vaccine prices. Some 950 million doses must be procured by self-financing, upper-middle and high income countries, in addition to the 2 billion doses set aside for lower income countries. A final pillar, the health systems connector, aims to strengthen the infrastructure and community networks required to deliver tools to people in need. Led by the World Bank, and the Global Fund, the pillar aims to build lab capacity, train staff to safely manage COVID-19, and to use new tools as they are deployed. Image Credits: Flickr: IAEA Imagebank/Natalia Khurtsidze, PR Manager of the Clinic. Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts This site uses cookies to help give you the best experience on our website. Cookies enable us to collect information that helps us personalise your experience and improve the functionality and performance of our site. By continuing to read our website, we assume you agree to this, otherwise you can adjust your browser settings. Please read our cookie and Privacy Policy. Our Cookies and Privacy Policy Loading Comments... You must be logged in to post a comment.
Swelling Indian National Opposition As Modi Plans To Expand Coal Mining 30/06/2020 Jyoti Pande Lavakare Coal miners in India’s resource-rich Meghalaya State. A government tribunal banned coal mining in the region in 2015. New Delhi, India – Prime Minister Narendra’s Modi’s ambitious plan to use coal to power India’s economic revival after his government’s strict lockdowns flattened the wrong curve, bringing economic growth to a halt even as the infection epidemic curve continued to rise, seems to have run into significant opposition from unexpected quarters. Since the launch of his plan earlier this month, state after Indian state has expressed disagreement with the Centre’s plan to commercially auction coal mines to the private sector, including international players. The latest to join the clamour of opposition by the states of Chhattisgarh, Jharkhand and Maharashtra, where more than half of the 41 mines are located – is the politically powerful chief minister of West Bengal, Mamata Banerjee. Indian environmentalists have also decried a seemingly desperate announcement by the government to auction off 41 Indian coal mines, opening a largely government-controlled sector up to all private investment for the first time ever – and thus greatly accelerating domestic coal production. Coal mining by Eastern Coalfields Ltd., the company that operates national coalfields in Jharkhand and West Bengal states. As of now, two government-owned mines produce over 90 % of India’s coal. Indian coal, known for its high fly ash content– and therefore pollution emissions – currently supplies about 80% of the country’s total coal needs, while the rest is imported. Coal, in turn, powers about 44% of the total energy needs, compared to oil (24%) and biomass (22%) – though the latter is often burned in highly polluting domestic cookstoves emitting climate-changing black carbon particles. Also, hydroelectric power supplies 1.4% of the economy, leaving solar and wind to supply only around 0.8% of the country’s total power needs. When it comes to electricity generation, the picture is just a little bit better. Coal powers 73% of electricity in India, while solar and wind fuel around 8% and hydro around 12% respectively, said Karthik Ganesan, Research Fellow, Council on Energy, Environment and Water. Clean air campaigners had hoped that the glimpse of blue skies, clean water bodies and nature restoring itself in the limbo provided by the lockdown of all growth engines would encourage decision-makers to choose a growth recovery path that had low environmental impact. Health and environmentalist activists had expected the government to look at growth recovery more holistically, which meant including developmental indicators like health, education and quality of life – in the spirit of the recent WHO manifesto for a healthy green recovery, which calls to put a stop to fossil fuel subsidies using taxpayer money. Unfortunately, India seems to be ignoring all of the recent health and climate warming signals – the latest being the swarms of locusts that are invading parts of the country as it focuses on coal to fuel its recovery. Ostensibly, Modi’s rationale is that the move will help make India energy self-sufficient and quickly claw back the robust growth curve that had begun to fall off even before the COVID-19 pandemic struck the country. However, investing heavily in coal also serves some of his key political alliances, some of whom – like the Adani Group – are also planning to export massive new coal reserves from Australia to India. Opposition to Modi’s Move Growing in India Existing, new, and planned coal mines in India (Credit: R. Pearce, T. Prater, S. Evans/Carbon Brief) Despite the pressing economic challenges that India admittedly does face, some leading Indian politicians are beginning to speak out in opposition to the coal mining plans – bringing this sector back into centre stage for the first time since “Coalgate,’ a coal scam that tainted the previous government a decade ago. Jharkhand state has already approached the Supreme Court challenging this auction, followed by Chhattisgarh and Maharashtra writing to the central environment minister Prakash Javadekar objecting to the auction. The latest to join the rising voice of critics is the feisty Chief Minister of West Bengal (and Modi’s bete noire) Mamata Banerjee, known for her blunt statements and ability to stand up to the central government. Last Thursday, Ms Banerjee wrote to Modi on Thursday, asking him to reconsider the decision, saying that “this policy can neither bring foreign direct investments not can it bring technologies or know-how which we are unable to access today,” and noting that global investors are more interested in renewable energy projects rather than coal, which offers low returns. None of the 41 mines coming up for auction are located in her state. Her objection is in principle and adds political weight to the growing opposition. States like Jharkhand, Maharashtra and Chhattisgarh, where more than half the mines coming up for auction are located, have already voiced opposition to this decision, citing huge environmental and social costs: “Riding on coal could spur the economy in the very short term and an extremely high ecological and social cost”, said Niraj Bhatt, Researcher in Environment and Climate Action for the Chennai-based Citizen consumer and civic Action Group (CAG), who works in the coal sector. The long term costs of promoting coal are disastrous, even in the government’s very first Climate Assessment report. The report warns of a four-fold increase in heat wave frequency and a doubling in the length of heat waves in India by 2100. “It is inexplicable why the government is prioritizing coal for fast track revival of the Indian economy since the pandemic”, given the knowledge that’s available, added Bhatt. Many local communities also are opposed to the government’s decision to privatize coal mining, fearing that this will degrade the environment. Most of the 41 coal mines in auction are in pristine forest areas. Even at the village-level, several panchayats (local governance bodies that make the fundamental building blocks of governance) have asked Modi to withdraw this auction. “Nine village panchayats from Hasdeo Arand forest region have written to the Prime-minister asking for withdrawing the auction of five coal blocks in the region for commercial mining as it would impact their livelihood and culture,” said Avinash Kumar Chanchal, a grassroots climate activist who has written on the degradation of the Singrauli coal belt and displacement of local communities. UN Secretary General Also Decries Coal Plans There is no good reason for any country to include coal in their #COVID19 recovery plans. This is the time to invest in energy sources that don’t pollute, generate decent jobs and save money. — António Guterres (@antonioguterres) June 29, 2020 United Nations Secretary-General Antonio Guterres has said there is no reason for any country to include coal in the COVID-19 recovery plans. Instead, investments should be made towards non-polluting energy sources; and opposition to a “black, coal-powered recovery” has grown in India. It isn’t clear whether this diplomatic rap on the knuckles and growing opposition will succeed in stopping the government in its polluting tracks, especially if Modi’s public statements on privatising coal mines – framed in his signature style with the bells and whistles of patriotism and nationalism for “atma-nirbharta” or self-reliance – are anything to go by. Desperate for funds and eager to kickstart a sluggish economy threatening to fall into a recession, the central government seems prepared to roadroll its way through. Its desperation stems from predictions of the most severe recession in the past the four decades – The International Monetary Fund has predicted a global annual downturn of 4.5%, though ratings firm India Ratings has predicted the Indian economy to contract by 5.3% this year. Renewable Energy Offers Untapped Potential Analysts say that the government is gambling on coal mining to generate over a million of jobs, as it is labour-intensive and rural communities are increasingly desperate for jobs following mass reverse migration since the pandemic began. Additionally, there is built-in momentum for coal power development, since it is already well-established and subsidized by the government – whereas renewables are a new game altogether, and energy storage issues still remain unresolved – as some critics claim. Activists and economists counter that government forces have ignored the potential of alternative energy sources at the current juncture: “There is huge potential to generate new jobs in renewable energy. Some analyses have estimated that more than one million jobs can be created by the renewable sector by 2022 if India can achieve its ambitious renewable target of 160GW,” said Chanchal. “The illusion of low cost energy from coal has been debunked globally. Socially, environmentally and economically, coal is very costly. It’s bad economic policy to invest in high cost options when cheaper alternatives exist today,” added Laveesh Bhandari, an economist turned environmental advocate, who works at the intersection of sustainable employment and climate change. “It’s almost as if we’re moving backwards. The whole world is moving away from coal. Several studies in India have shown the adverse effects of pollution caused by coal mining on the health of communities living within coal mining areas, especially on the respiratory system.” Even before pandemic, deaths from air pollution have been a major issue in India. In 2016, household pollution led to over a million deaths in India, according to the WHO’s Global Health Observatory; and in 2012, ambient air pollution claimed 620 000 Indian lives, with a shocking toll of over 20 million disability-adjusted life years (DALY), according to the WHO’s global assessment of exposure and burden of disease. However, now there is also the added factor of COVID-19, in which case chronic heavy exposures to air pollution will also increase vulnerability from the virus as well as mortality, said grassroots environmentalist and writer Rinchin, who goes by one name only and works with adivasis in Chhattisgarh. “Whether the Centre can still go ahead is a legal issue, but it will be bad form to go against the position of state governments. India is a federation, and something like mining that impacts not only the environment, but society itself therefore needs to be overseen, regulated and controlled by the state”, added Bhandari. India’s Ambition – Regional Energy Supplier? Coal mining in India While Modi is framing the coal auction as a move towards greater national self-reliance, the story is in fact more complex. His plan may involve ambitions to become a regional energy-producing power. It also aligns national policy with the commercial interests of close political allies – such as Indian billionaire Gautam Adani, and head of the powerful Adani group. Adani is leading the Carmichael project – a massive mining initiative to export Australian coal to India. Just last year, the Australia’s government gave the go-ahead for the project, the world’s largest open pit mine, overriding stiff opposition from Australian environmentalists. Adani plans to use the Australian coal for a new $2 billion power plant that his company is building in India, which will also produce electricity for sale in neighboring Bangladesh. Ever since Modi was the chief minister of the western state of Gujarat – Adani’s birthplace and home region – Adani and Modi were known to have close links. “The story of Adani and its Australian project illustrates why the world keeps burning coal despite its profound danger — and despite falling prices for options like natural gas, wind and solar,” the New York Times said last year. In fact, India’s coal ambitions under Modi will not just undermine existing efforts to limit climate change and worsen air and water pollution within the country, they are also likely to compromise the entire region, setting an undesirable example of fossil fuel dependency in neighbouring countries. Little Matter of Coal Gasification Air pollution in Delhi, India Then, there is that little matter of Modi’s plans for coal gasification – a technology that could further reduce India’s dependence on imports, but at an even higher level of carbon emissions – as well as potential water contamination from coal pollutants. The government’s current plan is to promote “syngas” -a substitute for imported liquified natural gas produced by coal gasification – to produce urea in fertilizer. This will not only help reduce liquified natural gas (LNG) imports but also urea imports, leading to a lower import bill and greater self-reliance. According to the Ministry of Chemicals and Fertilisers, urea is currently produced using pooled natural gas, which consists of both domestic natural gas and imported LNG. The usage of locally available coal for making fertilisers would help reduce the import of LNG, the Ministry has said. “The big question is when we have cleaner, cheaper, and sustainable renewable energy sources why do we want to invest in dirty and polluting technologies and energy sources? India is already facing a climate crisis,” said Chanchal. While natural gas is considered a lower climate emitter than coal, syngas is just the opposite. A study by Duke University found that syngas produced by coal gasification emits seven times more greenhouse gases than natural gas, making it a huge contributor to climate change. “It contaminates both surface water and groundwater, and also emits greenhouse gases. If renewable energy is available and becoming cheaper day by day, then why does the government want to start commercial mining to create coal based energy.” “Right now, the government is speaking like a climate leader but acting like a climate laggard by betting high on coal and promoting it,” added Bhatt. Mining Could Also Increase Dangerous Human-Wildlife Conflicts Dog sleeps on a bed of coal in Asansol, India Along with the climate and air pollution risks, activists have also warned that expanding mining operations in the areas up for auction could trigger increased human-wildlife conflict. “Among the 41 coal mines up for auction, most are situated in the dense forest of central India,” said Chanchal. “These forests are home to large populations of elephants and other wildlife. Some proposed coal blocks are also near tiger reserves, like in Maharashtra. “Along with vast forest destruction, coal mines will also increase the human-wildlife conflict. The implications are countless from the displacement of adivasis, to the violation of the Forest Rights Act, to public health,” said Chanchal, who has also written The Singrauli Files about the degradation of that region. “We have already seen how coal mines destroyed the rich biodiversity of places like Singrauli, Korba, and in other coal belts where thousands of adivasi and local communities were displaced, their forests, livelihood and human rights violated. They are already living with serious health crises,” he added. In a parallel move, Modi’s Ministry of Environment and Forestry also has launched an initiative to dilute existing environmental impact assessment norms for the creation of industries in pristine areas, including, but not limited to coal – a move that has been staunchly opposed by environmentalists – but action on that has been postponed by the courts until August. Modi Still Likely to Face Bureaucratic Challenges India’s Prime Minister Narendra Modi Despite the burgeoning opposition, Modi remains determined and eager to develop the private coal sector. Against the wave of new criticism he has remained silent – a typical tactic of response. However, India’s federal structure of governance may still slow down the realization of his vision considerably – giving environmentalist valuable time to mount a more organized local and global opposition. In the Indian governance model, the central government is expected to execute policy in consultation with state governments on a consensus model. More importantly, if the land is pristine forest land, as in this case, local self-governance laws and the FRA will make it challenging for it to move ahead with coal block allocation in such areas, which may still stave off this path to a quicker, but blacker, revival. “Land is a state subject, the Centre cannot go ahead without support from the states,” said Bhatt. “The implementation of the Forest Rights Act is also very crucial in these regions. The government which is promoting ‘atma-nirbhar Bharat’ should consider these concerns of local communities and take appropriate action to strengthen the self-governance of the gram sabha,” adds Chanchal. Image Credits: Environmental Change and Security Program, Flickr: Partha Sarathi Sahana, R. Pearce, T. Prater, S. Evans/Carbon Brief, Environmental Change and Security Program, Wikimedia Commons: Prami.ap90, Flickr: Partha Sarathi Sahana, Mike Bloomberg. World Surpasses 500,000 COVID-19 Deaths; Medicines Access Experts Challenge US $2340 Per Remdesivir Treatment Course Price Set By Gilead For Developed Countries 29/06/2020 Grace Ren Vial of remdesivir A six-vial five-day course of remdesivir – a promising COVID-19 treatment – will be priced at US $2340, or $390 per vial for developed countries, Gilead Sciences Chief Executive Officer Daniel O’Day wrote in an open letter on Monday. “Earlier hospital discharge [thanks to treatment by remdesivir] would result in hospital savings of approximately $12,000 per patient,” wrote O’Day. “We have decided to price remdesivir well below this value.” But the price is still high compared to the cost of manufacturing, according to medicines access experts, who say that remdesivir could be produced for below a dollar a day. Private insurers in the United States will pay US $3,120 for a five-day course, or $520 per vial. Out-of-pocket payments will be determined by individuals’ coverage plans. In 127 developing countries, Gilead has allowed generics companies to manufacture the drug, pricing a five-day course at about US $600. Cost of production for the drug can be as low as US $0.93 per day, according to a paper by Dr Andrew Hill, a senior visiting research fellow at the University of Liverpool, and his colleagues. “Gilead will turn a nice profit with its set price. Especially considering that the company has benefitted from significant government financing for the development of the drug; which apparently has not been discounted,” Ellen t’Hoen, director of Medicines, Law and Policy, told Health Policy Watch. electron microscope photo of SARS-CoV-2, the virus that causes COVID-19 “Based on publicly available data, it has been estimated that taxpayers have contributed at least $70.5 million to develop this drug,” Jessica Burry, a pharmacist at Médecins Sans Frontières Access Campaign, said to Health Policy Watch. “Additionally, contributions were made by various health organisations, including MSF, which supported clinical trials with this drug for Ebola in 2019. Patients themselves have also contributed by their participation in the trials. “Public funding and resources have contributed to the drug’s further development for COVID-19, and taxpayers will now end up essentially “paying twice” to access this treatment,” added Burry. The company could turn a US $2.3 billion profit on the “blockbuster” drug this year alone, according to a blog by Ellen t’Hoen. “This does put pharma’s lofty promises of not profiteering during the pandemic into perspective. I hope governments begin to realise that the important investments they make for the development of drugs and vaccines to respond to COVID-19 need to come with strings attached to ensure fair pricing and global access,” she said. COVID-19 Cases Surge Past 10,000,000, Deaths Reach Half A Million Meanwhile, the World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus warned on Monday that “the worst was yet to come.” Dr Tedros spoke at a press conference just as the number of deaths from COVID-19 topped half a million, and cumulative cases surged past 10,000,000. The US and Brazil continue to report around 40,000 new cases day. In the state of Texas, which saw one of the fastest rising daily case counts after reopening, hospitals in the capital city of Houston are nearing ICU capacity. Even as Vice President Mike Pence lauded the state’s reopening at a press briefing Monday, Texas Governor Greg Abbot warned that the epidemic had taken a “very swift and very dangerous turn.” Abbot shut down bars and clubs again across the state in an attempt to limit the fast-spreading virus. Remdesivir Pricing Announcement Comes On Heels Of EMA Conditional Marketing Authorization Endorsement Remdesivir, a failed Ebola antiviral, is one of the frontrunner drugs for treating COVID-19. It was shown to significantly reduce the length of hospital stay from an average of 11 days to an average of 15 days in a recent trial funded by the US National Institute of Allergies and Infectious Diseases (NIAID). However, the NIAID trial results were based on a 10-day treatment course, rather than the 5-day course that Gilead has currently priced. And studies have so far not reported any effects in reducing mortality. Still, the European Medicines Agency recently renewed their endorsement of the drug, recommending the agency give remdesivir conditional marketing authorization – a stamp of approval that many European Union countries use as guidance for approving drugs for diseases with few cures. Remdesivir is currently approved for use in Japan for COVID-19 patients. The United States Food and Drug Administration has approved the treatment for ’emergency’ use, just two days after the NIAID trial results were announced. The announcement comes just as Gilead’s promise to donate remdesivir until the end of June 2020 hits its deadline. US Health and Human Services Secretary Alex Azar announced Monday that the government had secured another half a million treatment courses of remdesivir for U.S. hospitals through September, according to an interview with “Good Morning America.” Health and Human Services will be paying the US $390 per vial price, and be responsible for allocating Gilead’s supply of remdesivir, according to O’Day’s letter. But some middle income countries that are hoping to secure their own supply of remdesivir may be out of luck, according to Burry. “Gilead has entered into license agreements with several generic companies in India, Pakistan and Egypt. The license, however, excludes nearly half of the world’s population, including most South American countries and a number of middle-income countries, such as Brazil, Russia and China,” said Burry. “Since the corporation has barely been able to supply enough quantities of this drug even to the US, it is highly unlikely that it will be able to meet the demands of all the other countries that have not been included in this license.” Brazil Signs Contract To Produce AstraZeneca & Oxford COVID-19 Vaccine Candidate; China Approves CanSino Vaccine Candidate For Military Use In a parallel development, Brazil on Saturday signed a contract with AstraZeneca and Oxford to manufacture an experimental COVID-19 vaccine candidate. Meanwhile, China approved the CanSino COVID-19 vaccine candidate for military use on Thursday. Local vaccine manufacturer Fiocruz will be producing up to 100 million doses of the vaccine overall, Brazilian authorities announced at a press briefing. The country will pay $127 million to receive material to produce 30.4 million doses in two batches in December and January, with the rest to come later. China’s Central Military Commission approved the CanSino vaccine for use by the military for a period of one year beginning 25 June 2020, according to a CanSino filing. The Academy of Military Sciences had jointly developed the vaccine candidate with CanSino. Results from a small, non-randomized trial released in May found that about 75% of people who received high doses of the CanSino vaccine candidate developed antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, after 28 days. However, the developers highlight that large, randomized control trials must be done in order to determine if the vaccine truly protects against infection by the virus. And other researchers pointed to old concerns with the Ad5 vector used in the CanSino vaccine. Previous Ad5-vectored vaccine candidates for HIV were dropped after early trials showed the experimental vaccine inadvertently increased the risk of HIV infection. This story was updated 30 June 2020. Image Credits: European Medicines Agency, NIAID, World Health Organization, NIAID. Gender-Based Violence – The “Shadow Pandemic” Of COVID-19 26/06/2020 Paul Adepoju While a face mask could provide some protection against COVID-19, the lives of many women in Africa, and elsewhere, are at the mercy of their abusers. (Photo Credit: Paul Adepoju) Ibadan, Nigeria – Twenty-two year-old Uwaila Vera Omozuwa, freshly admitted to university, had retreated to study in a church in the city of Benin, Nigeria during lockdown, when she was raped and killed on May 30. The following day, 18-year-old Barakat Bello was reportedly raped and killed in Oyo state. 29-year-old Azeezat Shomuyiwa and 21-year-old Grace Oshiagwu also suffered similar fates just days and few streets apart. In late March 2020, a video from Ghana surfaced on social media showing a boyfriend assaulting his girlfriend. As the COVID-19 pandemic continues to expand globally, African countries as well as other nations worldwide are also dealing with another related pandemic – that of gender-based violence. The stress triggered by COVID-19 lockdowns and economic uncertainty is exacerbating violent assaults, according to experts speaking at a panel last week hosted by the WHO Regional Office for Africa. Effectively, the pandemic has forced many women who are in abusive relationships to remain shut up at home with their abusers, further escalating their risks, they said. Social media responses condemning the gruesome murder and rape of Vera Uwaila Omozuwa. (Photo Credit: Youth Alive Foundation ) A “Shadow Pandemic” Gender-based violence is a “shadow pandemic” to COVID-19 said UN Women’s Executive Director, Phumzile Mlambo-Ngcuka. She noted that in Africa as well as elsewhere in the world, domestic violence hotlines and shelters are reporting rising calls for help. “Confinement is fostering the tension and strain created by security, health, and money worries. And it is increasing isolation for women with violent partners, separating them from the people and resources that can best help them,” Mlambo-Ngcuka said in a statement on violence against women and girls. “It’s a perfect storm for controlling, violent behaviour behind closed doors. And in parallel, as health systems are stretching to breaking point, domestic violence shelters are also reaching capacity, a service deficit made worse when centres are repurposed for additional COVID-response.” Africa has struggled with social attitudes sanctioning violent attacks on women, well before the pandemic began. For instance, in 2017, researchers at the University of Ghana reported that men who were in consensual unions or customary marriages remained in favour of wife beating. Police attitudes are often lax as well. Following Uwaila’s rape and murder in Benin, Nigeria, for instance, the local police initially demanded a “mobilization money” from the family to open an investigation, according to the victim’s sister, who finally led a protest to the Edo State police headquarters to trigger action – which she videotaped on Instagram. Now, in the period of COVID-19, for every 3 months lockdowns are imposed or continue, an additional 15 million extra cases of gender-based violence could be recorded worldwide, states a new report, COVID-19: A Gender Lens, by the UN Population Fund (UNFPA). And six months of lockdown could result in additional 31 million cases of gender-based violence in the world. Photo Credit: UN Women While the most extreme outcome, gender-based violence is not the only way women are suffering from lockdown restrictions, noted Dr. Natalia Kanem, UNFPA Executive Director while unveiling a new analysis by UNFPA and partners. “Millions more women and girls now risk losing the ability to plan their families and protect their bodies and their health,” she said, noting that women often cannot get to health services for basic care. “Women’s reproductive health and rights must be safeguarded at all costs. The services must continue; the supplies must be delivered; and the vulnerable must be protected and supported.” Fighting the Shadow Pandemic In Africa, political leaders have generally been reluctant to make themselves the face of campaigns against gender-based violence, the panel participants observed, recommending that Africa’s political leaders need to start speaking up now. “African leaders need to declare this situation as another pandemic and appeal to people, men, society, and those who set norms. African leaders need to speak up and recognise this is happening,” said Dr Matshidiso Moeti, WHO African Regional Director while speaking on the panel. Governments also need to make gender-violence prevention initiatives integral to economic and healthcare programmes dealing with COVID-19, she said. Matshidiso Moeti Specifically, she mentioned that police officers and health workers in African countries need to be made aware of the roles they are supposed to play in prevention of gender-based violence. For countries that are still in the dark over what to do, she noted that the government can work with men and women groups to improve the level of public education, provision of call numbers to report cases of abuse, and establishment of shelters to provide help and services to victims. “These can be part of the socio-economic response to the pandemic,” Moeti added. While most African countries now have legislation against gender-based violence, political leadership is still missing, agreed Winnie Byanyima, Executive Director of the Joint United Nations Programme on HIV/AIDS (UNAIDS). “I so rarely hear a male African leader speaking and leading on this issue. Most African leaders leave it to others, yet it is a pandemic – a silent one too,” Byanyima said. For Africa to advance in tackling gender-based violence, African leaders must be saddled with the responsibility of providing political leadership, she said. One leader that has spoken up recently was South African President Cyril Ramaphosa, a political powerful voice, as he is also the head of the African Union. Speaking to the media last week, he blamed the reopening of liquor stores as lockdown measures eased for a spate of attacks on women in that country. Those included pregnant, Tshegofatso Pule who was found hanging from a tree, Naledi Phangindawo, who was stabbed, and Sanele Mfaba whose body was later found in a Soweto township. South African campaigners note that in fact violence against women shot up from the moment the lockdowns began. The police force’s gender-based violence hotline received 2,300 calls in the first five days – nearly three times the rate prior to lockdown. Even so, Ramaphosa’s remarks were significant as this represented one of the few instances when an African Head of State has spoken out forcefully on the issue. Community-based Prevention and Education Are Key While some actions are being taken to improve Africa’s response to gender-based violence including building police and judiciary systems that understand their roles and can prosecute cases of gender-based violence, more needs to be done about awareness-raising and education that can prevent crimes from ever occurring, stressed Byanyima. “In my view, we are weakest on prevention. You need aggressive campaigns discouraging violent behaviors of boys and men, especially the way they see their masculinity and how they exercise it. That discouragement still needs to happen,” Byanyima said. Presently, this duty is largely left to civil societies and women organisations, but Byanyima noted that it is the business of the government to invest in continual campaigning in communities to change how relationships can be managed without violence. Winnie Byanyima “This is about men’s behavior – the way men are raised and see themselves as men. Tackling toxic masculinity is something that is not well invested in,” she said. Another necessary action to tackle the silent pandemic is to empower girls and women in African societies. Citing data from HIV, the UNAIDS Executive Director noted that an African girl’s vulnerability to HIV, sexual violence, unintended pregnancy and early marriage reduce by up to 50% if she is able to complete high school. But while African leaders have ratified universal basic education requiring every child to get at least primary education, two-thirds of children in Africa do not have access to secondary education. “The time for secondary education has come. We fought for universal primary education in Beijing and within ten years we have achieved it. Now we need to draw the line and say every government worth its name must put its kids, boys and girls, through high school. Not only for the knowledge economy but also for the safety and empowerment of girls and fighting gender-based violence,” Byanyima said. Story of Success: Experts Laud Rwanda’s One Stop Center For Sexual Violence Bineta Diop, African Union’s Special Envoy on Women Peace & Security, recommended African governments adopting Rwanda’s one-stop center for sexual violence. Located within the Kacyiru Police Hospital, the Isange One Stop Centre, the Isange One Stop Center has become a hub for gender-based violence survivors. At the center, survivors can access all the required services in one place and for free. The center is operated by the country’s Gender and Family Promotion, of Health, and Justice ministries in addition to the Rwanda National Police. Bineta Diop The initiative that started in 2009 as a pilot has since been expanded across the country. Rwanda now has a One Stop Centre in every district. Every day, up to 12 survivors are received at the center. “28% are survivors of intimate partner violence and 78 percent are survivors of sexual violence. Of the 78% of survivors who have been sexually assaulted, 16% are younger than 5 years,” said Daniel Nyamwasa, Commissioner of Police and Chief Infectologist Consultant at the hospital. Diop also encouraged African governments to acquire DNA testing capabilities to provide evidence that could be used to prosecute cases of rape and other gender-based violence against women and girls. Enlisting More Women in Police and Judiciary Another solution is the enlistment of more women in the police and judiciary systems across the continent which Diop said will encourage more women to approach the legal system to file complaints. She also called for the engagement of Africa’s traditional leaders. “If you want to break the patriarchal system, you have to engage the traditional system,” Diop said. However, as the number of confirmed cases of COVID-19 in Africa is increasing, African governments are also focusing on how to quickly and safely reopen their economies to minimize the impact of the pandemic. This current reality threatens the materialization of recommendations giving more attention to combating gender-based violence. But Ramaphosa, for one, has said this does not have to be the case. In his comments last week, he stressed that action can and should be taken to combat violence, despite the numerous familiar and peculiar challenges that countries across the continent are facing: “For public faith in the criminal justice system to be maintained, gender-based violence needs to be treated with the urgency it deserves by our communities working together with our police.” Cyril Ramaphosa, President of South Africa Image Credits: Paul Adepoju, Twitter: Youth Alive Foundation, UN Women. Massive Mobilization Of US $31.3 Billion Required For COVID-19 Diagnostics, Drugs & Vaccines Accelerator 26/06/2020 Grace Ren Central Laboratory at the Academician Nikoloz Kipshidze University Clinic, Tbilisi, Georgia, receives laboratory equipment for COVID-19 diagnosis. The World Health Organization aims to raise a whopping US $31.3 billion to fund the ambitious goals of the Access to COVID-19 Tools (ACT) Accelerator; a multi-stakeholder initiative that aims to develop and deploy diagnostics, drugs, and vaccines to control the virus. But so far, only $US 3.4 billion has been pledged towards the initial goals. And US $13.7 billion is ‘urgently needed’ in order to cover immediate needs, according to an investment case released by WHO on Friday. “Though these numbers sound big, they are not. If we spend billions now, we will avoid spending trillions later. The time to act is now, and the way to act is together,” said Gavi Board Chair Ngozi Okonjo-Iweala. The funding will go toward: Scaling up development and delivery of 500 million diagnostic tests to low- and middle-income countries (LMICS) by mid-2021 Delivering 245 million courses of treatments to LMICs by mid-2021, Delivering 2 billion vaccine doses, of which 50% will go to LMICs by the end of 2021. “It’s clear that because all people are at risk of COVID-19, all people should have access to all the tools to prevent, detect and treated, not only those who can afford to pay for them,” said World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus at a Friday press briefing. “We have made the principle of equitable access a simple thing to say, but a complicated thing to implement.” Dr Tedros at the 26 June press briefing More than 9 million people have been infected, and nearly half a million have so far lost their lives to the virus. The investment required in the Accelerator is less than a tenth of the loss the global economy is facing every month due to the pandemic, according to International Monetary Fund estimates. “The cost of inaction now is quite important to take into consideration,” said Philippe Duneton, executive director of UNITAID, working with the Wellcome Trust on the therapeutics pillar of the project. A good portion of the immediate investments will go towards preparing markets to absorb new COVID-19 technologies, setting up demand, manufacturing, and country capacity to roll out any new diagnostics, vaccines, or drugs. Four Investment Pillars Require Urgent Funding The ACT Accelerator operates under four main pillars – diagnostics, therapeutics, vaccines, and the health systems connector. The diagnostics pillar, co-led by FIND and the Global Fund to Fight AIDS, Tuberculosis, and Malaria, aims to avoid 1.6 billion further infections by scaling up access to diagnostics. The pillar requires US $6 billion in the next year, but US $2 billion is urgently needed to begin deploying tests now. Ultimately, 10,000 healthcare workers will be needed. “The real strategy towards containing the epidemic is through testing, tracing, isolation; and the starting point for that is a very rapid rollout of very large numbers of tests,” said Peter Sands, executive director of the Global Fund. “To underscore the urgency for many lower middle income countries, lockdown is not sustainable. Households don’t have the wherewithal to continue without working, and governments don’t have the ability to compensate for lost income, coupled with the fact that clinical care facilities are extremely limited.” The therapeutics pillar will focus on accelerating the development and deployment of effective treatments. While no drugs have yet been tapped, the pillar aims to provide 250 million courses of treatment to LMICS in the next 12 months. Some US$11.6 billion is needed in the next year, while US $3.8 billion is needed immediately. “Of course, as soon as we have a medicine, the situation at the country level will also be a challenge,” said Duneton. “The access to oxygen, for example, is not the same in all countries.” But “the only way to prevent further transmission [of the virus] and to break that cycle, would be to have an effective and safe vaccine available to people,” said WHO Chief Scientist Soumya Swaminathan. Soumya Swaminathan speaks at the 26 June ACT Accelerator press briefing The vaccines pillar has an ambitious goal of delivering 2 billion doses by the end of 2021. Seven candidates are currently in clinical trials, but none have yet received regulatory approval. So far, the fastest vaccine to move from lab bench to approval for human use was the Ebola vaccine – which took five years to develop. “In general, it takes 8 to 10 years for a vaccine to move from when the research begins to when it gets into people. We want to shorten that timeline as short as possible – 12 months, 18 months maximum,” said Swaminathan. “That would be unprecedented, and can only happen through global collaboration.” The Coalition for Epidemic Preparedness Innovation (CEPI), and Gavi, the Vaccine Alliance, will lead the vaccines pillar alongside WHO, which will provide oversight of regulation, policy and allocation. Some US $18.1 billion is required to safely deliver the vaccine to people in need. Gavi, through an advanced market agreement under its COVAX Facility, aims to pool purchasing power from nations of all income levels to secure low vaccine prices. Some 950 million doses must be procured by self-financing, upper-middle and high income countries, in addition to the 2 billion doses set aside for lower income countries. A final pillar, the health systems connector, aims to strengthen the infrastructure and community networks required to deliver tools to people in need. Led by the World Bank, and the Global Fund, the pillar aims to build lab capacity, train staff to safely manage COVID-19, and to use new tools as they are deployed. Image Credits: Flickr: IAEA Imagebank/Natalia Khurtsidze, PR Manager of the Clinic. Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts This site uses cookies to help give you the best experience on our website. Cookies enable us to collect information that helps us personalise your experience and improve the functionality and performance of our site. By continuing to read our website, we assume you agree to this, otherwise you can adjust your browser settings. Please read our cookie and Privacy Policy. Our Cookies and Privacy Policy Loading Comments... You must be logged in to post a comment.
World Surpasses 500,000 COVID-19 Deaths; Medicines Access Experts Challenge US $2340 Per Remdesivir Treatment Course Price Set By Gilead For Developed Countries 29/06/2020 Grace Ren Vial of remdesivir A six-vial five-day course of remdesivir – a promising COVID-19 treatment – will be priced at US $2340, or $390 per vial for developed countries, Gilead Sciences Chief Executive Officer Daniel O’Day wrote in an open letter on Monday. “Earlier hospital discharge [thanks to treatment by remdesivir] would result in hospital savings of approximately $12,000 per patient,” wrote O’Day. “We have decided to price remdesivir well below this value.” But the price is still high compared to the cost of manufacturing, according to medicines access experts, who say that remdesivir could be produced for below a dollar a day. Private insurers in the United States will pay US $3,120 for a five-day course, or $520 per vial. Out-of-pocket payments will be determined by individuals’ coverage plans. In 127 developing countries, Gilead has allowed generics companies to manufacture the drug, pricing a five-day course at about US $600. Cost of production for the drug can be as low as US $0.93 per day, according to a paper by Dr Andrew Hill, a senior visiting research fellow at the University of Liverpool, and his colleagues. “Gilead will turn a nice profit with its set price. Especially considering that the company has benefitted from significant government financing for the development of the drug; which apparently has not been discounted,” Ellen t’Hoen, director of Medicines, Law and Policy, told Health Policy Watch. electron microscope photo of SARS-CoV-2, the virus that causes COVID-19 “Based on publicly available data, it has been estimated that taxpayers have contributed at least $70.5 million to develop this drug,” Jessica Burry, a pharmacist at Médecins Sans Frontières Access Campaign, said to Health Policy Watch. “Additionally, contributions were made by various health organisations, including MSF, which supported clinical trials with this drug for Ebola in 2019. Patients themselves have also contributed by their participation in the trials. “Public funding and resources have contributed to the drug’s further development for COVID-19, and taxpayers will now end up essentially “paying twice” to access this treatment,” added Burry. The company could turn a US $2.3 billion profit on the “blockbuster” drug this year alone, according to a blog by Ellen t’Hoen. “This does put pharma’s lofty promises of not profiteering during the pandemic into perspective. I hope governments begin to realise that the important investments they make for the development of drugs and vaccines to respond to COVID-19 need to come with strings attached to ensure fair pricing and global access,” she said. COVID-19 Cases Surge Past 10,000,000, Deaths Reach Half A Million Meanwhile, the World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus warned on Monday that “the worst was yet to come.” Dr Tedros spoke at a press conference just as the number of deaths from COVID-19 topped half a million, and cumulative cases surged past 10,000,000. The US and Brazil continue to report around 40,000 new cases day. In the state of Texas, which saw one of the fastest rising daily case counts after reopening, hospitals in the capital city of Houston are nearing ICU capacity. Even as Vice President Mike Pence lauded the state’s reopening at a press briefing Monday, Texas Governor Greg Abbot warned that the epidemic had taken a “very swift and very dangerous turn.” Abbot shut down bars and clubs again across the state in an attempt to limit the fast-spreading virus. Remdesivir Pricing Announcement Comes On Heels Of EMA Conditional Marketing Authorization Endorsement Remdesivir, a failed Ebola antiviral, is one of the frontrunner drugs for treating COVID-19. It was shown to significantly reduce the length of hospital stay from an average of 11 days to an average of 15 days in a recent trial funded by the US National Institute of Allergies and Infectious Diseases (NIAID). However, the NIAID trial results were based on a 10-day treatment course, rather than the 5-day course that Gilead has currently priced. And studies have so far not reported any effects in reducing mortality. Still, the European Medicines Agency recently renewed their endorsement of the drug, recommending the agency give remdesivir conditional marketing authorization – a stamp of approval that many European Union countries use as guidance for approving drugs for diseases with few cures. Remdesivir is currently approved for use in Japan for COVID-19 patients. The United States Food and Drug Administration has approved the treatment for ’emergency’ use, just two days after the NIAID trial results were announced. The announcement comes just as Gilead’s promise to donate remdesivir until the end of June 2020 hits its deadline. US Health and Human Services Secretary Alex Azar announced Monday that the government had secured another half a million treatment courses of remdesivir for U.S. hospitals through September, according to an interview with “Good Morning America.” Health and Human Services will be paying the US $390 per vial price, and be responsible for allocating Gilead’s supply of remdesivir, according to O’Day’s letter. But some middle income countries that are hoping to secure their own supply of remdesivir may be out of luck, according to Burry. “Gilead has entered into license agreements with several generic companies in India, Pakistan and Egypt. The license, however, excludes nearly half of the world’s population, including most South American countries and a number of middle-income countries, such as Brazil, Russia and China,” said Burry. “Since the corporation has barely been able to supply enough quantities of this drug even to the US, it is highly unlikely that it will be able to meet the demands of all the other countries that have not been included in this license.” Brazil Signs Contract To Produce AstraZeneca & Oxford COVID-19 Vaccine Candidate; China Approves CanSino Vaccine Candidate For Military Use In a parallel development, Brazil on Saturday signed a contract with AstraZeneca and Oxford to manufacture an experimental COVID-19 vaccine candidate. Meanwhile, China approved the CanSino COVID-19 vaccine candidate for military use on Thursday. Local vaccine manufacturer Fiocruz will be producing up to 100 million doses of the vaccine overall, Brazilian authorities announced at a press briefing. The country will pay $127 million to receive material to produce 30.4 million doses in two batches in December and January, with the rest to come later. China’s Central Military Commission approved the CanSino vaccine for use by the military for a period of one year beginning 25 June 2020, according to a CanSino filing. The Academy of Military Sciences had jointly developed the vaccine candidate with CanSino. Results from a small, non-randomized trial released in May found that about 75% of people who received high doses of the CanSino vaccine candidate developed antibodies that neutralized SARS-CoV-2, the virus that causes COVID-19, after 28 days. However, the developers highlight that large, randomized control trials must be done in order to determine if the vaccine truly protects against infection by the virus. And other researchers pointed to old concerns with the Ad5 vector used in the CanSino vaccine. Previous Ad5-vectored vaccine candidates for HIV were dropped after early trials showed the experimental vaccine inadvertently increased the risk of HIV infection. This story was updated 30 June 2020. Image Credits: European Medicines Agency, NIAID, World Health Organization, NIAID. Gender-Based Violence – The “Shadow Pandemic” Of COVID-19 26/06/2020 Paul Adepoju While a face mask could provide some protection against COVID-19, the lives of many women in Africa, and elsewhere, are at the mercy of their abusers. (Photo Credit: Paul Adepoju) Ibadan, Nigeria – Twenty-two year-old Uwaila Vera Omozuwa, freshly admitted to university, had retreated to study in a church in the city of Benin, Nigeria during lockdown, when she was raped and killed on May 30. The following day, 18-year-old Barakat Bello was reportedly raped and killed in Oyo state. 29-year-old Azeezat Shomuyiwa and 21-year-old Grace Oshiagwu also suffered similar fates just days and few streets apart. In late March 2020, a video from Ghana surfaced on social media showing a boyfriend assaulting his girlfriend. As the COVID-19 pandemic continues to expand globally, African countries as well as other nations worldwide are also dealing with another related pandemic – that of gender-based violence. The stress triggered by COVID-19 lockdowns and economic uncertainty is exacerbating violent assaults, according to experts speaking at a panel last week hosted by the WHO Regional Office for Africa. Effectively, the pandemic has forced many women who are in abusive relationships to remain shut up at home with their abusers, further escalating their risks, they said. Social media responses condemning the gruesome murder and rape of Vera Uwaila Omozuwa. (Photo Credit: Youth Alive Foundation ) A “Shadow Pandemic” Gender-based violence is a “shadow pandemic” to COVID-19 said UN Women’s Executive Director, Phumzile Mlambo-Ngcuka. She noted that in Africa as well as elsewhere in the world, domestic violence hotlines and shelters are reporting rising calls for help. “Confinement is fostering the tension and strain created by security, health, and money worries. And it is increasing isolation for women with violent partners, separating them from the people and resources that can best help them,” Mlambo-Ngcuka said in a statement on violence against women and girls. “It’s a perfect storm for controlling, violent behaviour behind closed doors. And in parallel, as health systems are stretching to breaking point, domestic violence shelters are also reaching capacity, a service deficit made worse when centres are repurposed for additional COVID-response.” Africa has struggled with social attitudes sanctioning violent attacks on women, well before the pandemic began. For instance, in 2017, researchers at the University of Ghana reported that men who were in consensual unions or customary marriages remained in favour of wife beating. Police attitudes are often lax as well. Following Uwaila’s rape and murder in Benin, Nigeria, for instance, the local police initially demanded a “mobilization money” from the family to open an investigation, according to the victim’s sister, who finally led a protest to the Edo State police headquarters to trigger action – which she videotaped on Instagram. Now, in the period of COVID-19, for every 3 months lockdowns are imposed or continue, an additional 15 million extra cases of gender-based violence could be recorded worldwide, states a new report, COVID-19: A Gender Lens, by the UN Population Fund (UNFPA). And six months of lockdown could result in additional 31 million cases of gender-based violence in the world. Photo Credit: UN Women While the most extreme outcome, gender-based violence is not the only way women are suffering from lockdown restrictions, noted Dr. Natalia Kanem, UNFPA Executive Director while unveiling a new analysis by UNFPA and partners. “Millions more women and girls now risk losing the ability to plan their families and protect their bodies and their health,” she said, noting that women often cannot get to health services for basic care. “Women’s reproductive health and rights must be safeguarded at all costs. The services must continue; the supplies must be delivered; and the vulnerable must be protected and supported.” Fighting the Shadow Pandemic In Africa, political leaders have generally been reluctant to make themselves the face of campaigns against gender-based violence, the panel participants observed, recommending that Africa’s political leaders need to start speaking up now. “African leaders need to declare this situation as another pandemic and appeal to people, men, society, and those who set norms. African leaders need to speak up and recognise this is happening,” said Dr Matshidiso Moeti, WHO African Regional Director while speaking on the panel. Governments also need to make gender-violence prevention initiatives integral to economic and healthcare programmes dealing with COVID-19, she said. Matshidiso Moeti Specifically, she mentioned that police officers and health workers in African countries need to be made aware of the roles they are supposed to play in prevention of gender-based violence. For countries that are still in the dark over what to do, she noted that the government can work with men and women groups to improve the level of public education, provision of call numbers to report cases of abuse, and establishment of shelters to provide help and services to victims. “These can be part of the socio-economic response to the pandemic,” Moeti added. While most African countries now have legislation against gender-based violence, political leadership is still missing, agreed Winnie Byanyima, Executive Director of the Joint United Nations Programme on HIV/AIDS (UNAIDS). “I so rarely hear a male African leader speaking and leading on this issue. Most African leaders leave it to others, yet it is a pandemic – a silent one too,” Byanyima said. For Africa to advance in tackling gender-based violence, African leaders must be saddled with the responsibility of providing political leadership, she said. One leader that has spoken up recently was South African President Cyril Ramaphosa, a political powerful voice, as he is also the head of the African Union. Speaking to the media last week, he blamed the reopening of liquor stores as lockdown measures eased for a spate of attacks on women in that country. Those included pregnant, Tshegofatso Pule who was found hanging from a tree, Naledi Phangindawo, who was stabbed, and Sanele Mfaba whose body was later found in a Soweto township. South African campaigners note that in fact violence against women shot up from the moment the lockdowns began. The police force’s gender-based violence hotline received 2,300 calls in the first five days – nearly three times the rate prior to lockdown. Even so, Ramaphosa’s remarks were significant as this represented one of the few instances when an African Head of State has spoken out forcefully on the issue. Community-based Prevention and Education Are Key While some actions are being taken to improve Africa’s response to gender-based violence including building police and judiciary systems that understand their roles and can prosecute cases of gender-based violence, more needs to be done about awareness-raising and education that can prevent crimes from ever occurring, stressed Byanyima. “In my view, we are weakest on prevention. You need aggressive campaigns discouraging violent behaviors of boys and men, especially the way they see their masculinity and how they exercise it. That discouragement still needs to happen,” Byanyima said. Presently, this duty is largely left to civil societies and women organisations, but Byanyima noted that it is the business of the government to invest in continual campaigning in communities to change how relationships can be managed without violence. Winnie Byanyima “This is about men’s behavior – the way men are raised and see themselves as men. Tackling toxic masculinity is something that is not well invested in,” she said. Another necessary action to tackle the silent pandemic is to empower girls and women in African societies. Citing data from HIV, the UNAIDS Executive Director noted that an African girl’s vulnerability to HIV, sexual violence, unintended pregnancy and early marriage reduce by up to 50% if she is able to complete high school. But while African leaders have ratified universal basic education requiring every child to get at least primary education, two-thirds of children in Africa do not have access to secondary education. “The time for secondary education has come. We fought for universal primary education in Beijing and within ten years we have achieved it. Now we need to draw the line and say every government worth its name must put its kids, boys and girls, through high school. Not only for the knowledge economy but also for the safety and empowerment of girls and fighting gender-based violence,” Byanyima said. Story of Success: Experts Laud Rwanda’s One Stop Center For Sexual Violence Bineta Diop, African Union’s Special Envoy on Women Peace & Security, recommended African governments adopting Rwanda’s one-stop center for sexual violence. Located within the Kacyiru Police Hospital, the Isange One Stop Centre, the Isange One Stop Center has become a hub for gender-based violence survivors. At the center, survivors can access all the required services in one place and for free. The center is operated by the country’s Gender and Family Promotion, of Health, and Justice ministries in addition to the Rwanda National Police. Bineta Diop The initiative that started in 2009 as a pilot has since been expanded across the country. Rwanda now has a One Stop Centre in every district. Every day, up to 12 survivors are received at the center. “28% are survivors of intimate partner violence and 78 percent are survivors of sexual violence. Of the 78% of survivors who have been sexually assaulted, 16% are younger than 5 years,” said Daniel Nyamwasa, Commissioner of Police and Chief Infectologist Consultant at the hospital. Diop also encouraged African governments to acquire DNA testing capabilities to provide evidence that could be used to prosecute cases of rape and other gender-based violence against women and girls. Enlisting More Women in Police and Judiciary Another solution is the enlistment of more women in the police and judiciary systems across the continent which Diop said will encourage more women to approach the legal system to file complaints. She also called for the engagement of Africa’s traditional leaders. “If you want to break the patriarchal system, you have to engage the traditional system,” Diop said. However, as the number of confirmed cases of COVID-19 in Africa is increasing, African governments are also focusing on how to quickly and safely reopen their economies to minimize the impact of the pandemic. This current reality threatens the materialization of recommendations giving more attention to combating gender-based violence. But Ramaphosa, for one, has said this does not have to be the case. In his comments last week, he stressed that action can and should be taken to combat violence, despite the numerous familiar and peculiar challenges that countries across the continent are facing: “For public faith in the criminal justice system to be maintained, gender-based violence needs to be treated with the urgency it deserves by our communities working together with our police.” Cyril Ramaphosa, President of South Africa Image Credits: Paul Adepoju, Twitter: Youth Alive Foundation, UN Women. Massive Mobilization Of US $31.3 Billion Required For COVID-19 Diagnostics, Drugs & Vaccines Accelerator 26/06/2020 Grace Ren Central Laboratory at the Academician Nikoloz Kipshidze University Clinic, Tbilisi, Georgia, receives laboratory equipment for COVID-19 diagnosis. The World Health Organization aims to raise a whopping US $31.3 billion to fund the ambitious goals of the Access to COVID-19 Tools (ACT) Accelerator; a multi-stakeholder initiative that aims to develop and deploy diagnostics, drugs, and vaccines to control the virus. But so far, only $US 3.4 billion has been pledged towards the initial goals. And US $13.7 billion is ‘urgently needed’ in order to cover immediate needs, according to an investment case released by WHO on Friday. “Though these numbers sound big, they are not. If we spend billions now, we will avoid spending trillions later. The time to act is now, and the way to act is together,” said Gavi Board Chair Ngozi Okonjo-Iweala. The funding will go toward: Scaling up development and delivery of 500 million diagnostic tests to low- and middle-income countries (LMICS) by mid-2021 Delivering 245 million courses of treatments to LMICs by mid-2021, Delivering 2 billion vaccine doses, of which 50% will go to LMICs by the end of 2021. “It’s clear that because all people are at risk of COVID-19, all people should have access to all the tools to prevent, detect and treated, not only those who can afford to pay for them,” said World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus at a Friday press briefing. “We have made the principle of equitable access a simple thing to say, but a complicated thing to implement.” Dr Tedros at the 26 June press briefing More than 9 million people have been infected, and nearly half a million have so far lost their lives to the virus. The investment required in the Accelerator is less than a tenth of the loss the global economy is facing every month due to the pandemic, according to International Monetary Fund estimates. “The cost of inaction now is quite important to take into consideration,” said Philippe Duneton, executive director of UNITAID, working with the Wellcome Trust on the therapeutics pillar of the project. A good portion of the immediate investments will go towards preparing markets to absorb new COVID-19 technologies, setting up demand, manufacturing, and country capacity to roll out any new diagnostics, vaccines, or drugs. Four Investment Pillars Require Urgent Funding The ACT Accelerator operates under four main pillars – diagnostics, therapeutics, vaccines, and the health systems connector. The diagnostics pillar, co-led by FIND and the Global Fund to Fight AIDS, Tuberculosis, and Malaria, aims to avoid 1.6 billion further infections by scaling up access to diagnostics. The pillar requires US $6 billion in the next year, but US $2 billion is urgently needed to begin deploying tests now. Ultimately, 10,000 healthcare workers will be needed. “The real strategy towards containing the epidemic is through testing, tracing, isolation; and the starting point for that is a very rapid rollout of very large numbers of tests,” said Peter Sands, executive director of the Global Fund. “To underscore the urgency for many lower middle income countries, lockdown is not sustainable. Households don’t have the wherewithal to continue without working, and governments don’t have the ability to compensate for lost income, coupled with the fact that clinical care facilities are extremely limited.” The therapeutics pillar will focus on accelerating the development and deployment of effective treatments. While no drugs have yet been tapped, the pillar aims to provide 250 million courses of treatment to LMICS in the next 12 months. Some US$11.6 billion is needed in the next year, while US $3.8 billion is needed immediately. “Of course, as soon as we have a medicine, the situation at the country level will also be a challenge,” said Duneton. “The access to oxygen, for example, is not the same in all countries.” But “the only way to prevent further transmission [of the virus] and to break that cycle, would be to have an effective and safe vaccine available to people,” said WHO Chief Scientist Soumya Swaminathan. Soumya Swaminathan speaks at the 26 June ACT Accelerator press briefing The vaccines pillar has an ambitious goal of delivering 2 billion doses by the end of 2021. Seven candidates are currently in clinical trials, but none have yet received regulatory approval. So far, the fastest vaccine to move from lab bench to approval for human use was the Ebola vaccine – which took five years to develop. “In general, it takes 8 to 10 years for a vaccine to move from when the research begins to when it gets into people. We want to shorten that timeline as short as possible – 12 months, 18 months maximum,” said Swaminathan. “That would be unprecedented, and can only happen through global collaboration.” The Coalition for Epidemic Preparedness Innovation (CEPI), and Gavi, the Vaccine Alliance, will lead the vaccines pillar alongside WHO, which will provide oversight of regulation, policy and allocation. Some US $18.1 billion is required to safely deliver the vaccine to people in need. Gavi, through an advanced market agreement under its COVAX Facility, aims to pool purchasing power from nations of all income levels to secure low vaccine prices. Some 950 million doses must be procured by self-financing, upper-middle and high income countries, in addition to the 2 billion doses set aside for lower income countries. A final pillar, the health systems connector, aims to strengthen the infrastructure and community networks required to deliver tools to people in need. Led by the World Bank, and the Global Fund, the pillar aims to build lab capacity, train staff to safely manage COVID-19, and to use new tools as they are deployed. Image Credits: Flickr: IAEA Imagebank/Natalia Khurtsidze, PR Manager of the Clinic. Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts This site uses cookies to help give you the best experience on our website. Cookies enable us to collect information that helps us personalise your experience and improve the functionality and performance of our site. By continuing to read our website, we assume you agree to this, otherwise you can adjust your browser settings. Please read our cookie and Privacy Policy. Our Cookies and Privacy Policy Loading Comments... You must be logged in to post a comment.
Gender-Based Violence – The “Shadow Pandemic” Of COVID-19 26/06/2020 Paul Adepoju While a face mask could provide some protection against COVID-19, the lives of many women in Africa, and elsewhere, are at the mercy of their abusers. (Photo Credit: Paul Adepoju) Ibadan, Nigeria – Twenty-two year-old Uwaila Vera Omozuwa, freshly admitted to university, had retreated to study in a church in the city of Benin, Nigeria during lockdown, when she was raped and killed on May 30. The following day, 18-year-old Barakat Bello was reportedly raped and killed in Oyo state. 29-year-old Azeezat Shomuyiwa and 21-year-old Grace Oshiagwu also suffered similar fates just days and few streets apart. In late March 2020, a video from Ghana surfaced on social media showing a boyfriend assaulting his girlfriend. As the COVID-19 pandemic continues to expand globally, African countries as well as other nations worldwide are also dealing with another related pandemic – that of gender-based violence. The stress triggered by COVID-19 lockdowns and economic uncertainty is exacerbating violent assaults, according to experts speaking at a panel last week hosted by the WHO Regional Office for Africa. Effectively, the pandemic has forced many women who are in abusive relationships to remain shut up at home with their abusers, further escalating their risks, they said. Social media responses condemning the gruesome murder and rape of Vera Uwaila Omozuwa. (Photo Credit: Youth Alive Foundation ) A “Shadow Pandemic” Gender-based violence is a “shadow pandemic” to COVID-19 said UN Women’s Executive Director, Phumzile Mlambo-Ngcuka. She noted that in Africa as well as elsewhere in the world, domestic violence hotlines and shelters are reporting rising calls for help. “Confinement is fostering the tension and strain created by security, health, and money worries. And it is increasing isolation for women with violent partners, separating them from the people and resources that can best help them,” Mlambo-Ngcuka said in a statement on violence against women and girls. “It’s a perfect storm for controlling, violent behaviour behind closed doors. And in parallel, as health systems are stretching to breaking point, domestic violence shelters are also reaching capacity, a service deficit made worse when centres are repurposed for additional COVID-response.” Africa has struggled with social attitudes sanctioning violent attacks on women, well before the pandemic began. For instance, in 2017, researchers at the University of Ghana reported that men who were in consensual unions or customary marriages remained in favour of wife beating. Police attitudes are often lax as well. Following Uwaila’s rape and murder in Benin, Nigeria, for instance, the local police initially demanded a “mobilization money” from the family to open an investigation, according to the victim’s sister, who finally led a protest to the Edo State police headquarters to trigger action – which she videotaped on Instagram. Now, in the period of COVID-19, for every 3 months lockdowns are imposed or continue, an additional 15 million extra cases of gender-based violence could be recorded worldwide, states a new report, COVID-19: A Gender Lens, by the UN Population Fund (UNFPA). And six months of lockdown could result in additional 31 million cases of gender-based violence in the world. Photo Credit: UN Women While the most extreme outcome, gender-based violence is not the only way women are suffering from lockdown restrictions, noted Dr. Natalia Kanem, UNFPA Executive Director while unveiling a new analysis by UNFPA and partners. “Millions more women and girls now risk losing the ability to plan their families and protect their bodies and their health,” she said, noting that women often cannot get to health services for basic care. “Women’s reproductive health and rights must be safeguarded at all costs. The services must continue; the supplies must be delivered; and the vulnerable must be protected and supported.” Fighting the Shadow Pandemic In Africa, political leaders have generally been reluctant to make themselves the face of campaigns against gender-based violence, the panel participants observed, recommending that Africa’s political leaders need to start speaking up now. “African leaders need to declare this situation as another pandemic and appeal to people, men, society, and those who set norms. African leaders need to speak up and recognise this is happening,” said Dr Matshidiso Moeti, WHO African Regional Director while speaking on the panel. Governments also need to make gender-violence prevention initiatives integral to economic and healthcare programmes dealing with COVID-19, she said. Matshidiso Moeti Specifically, she mentioned that police officers and health workers in African countries need to be made aware of the roles they are supposed to play in prevention of gender-based violence. For countries that are still in the dark over what to do, she noted that the government can work with men and women groups to improve the level of public education, provision of call numbers to report cases of abuse, and establishment of shelters to provide help and services to victims. “These can be part of the socio-economic response to the pandemic,” Moeti added. While most African countries now have legislation against gender-based violence, political leadership is still missing, agreed Winnie Byanyima, Executive Director of the Joint United Nations Programme on HIV/AIDS (UNAIDS). “I so rarely hear a male African leader speaking and leading on this issue. Most African leaders leave it to others, yet it is a pandemic – a silent one too,” Byanyima said. For Africa to advance in tackling gender-based violence, African leaders must be saddled with the responsibility of providing political leadership, she said. One leader that has spoken up recently was South African President Cyril Ramaphosa, a political powerful voice, as he is also the head of the African Union. Speaking to the media last week, he blamed the reopening of liquor stores as lockdown measures eased for a spate of attacks on women in that country. Those included pregnant, Tshegofatso Pule who was found hanging from a tree, Naledi Phangindawo, who was stabbed, and Sanele Mfaba whose body was later found in a Soweto township. South African campaigners note that in fact violence against women shot up from the moment the lockdowns began. The police force’s gender-based violence hotline received 2,300 calls in the first five days – nearly three times the rate prior to lockdown. Even so, Ramaphosa’s remarks were significant as this represented one of the few instances when an African Head of State has spoken out forcefully on the issue. Community-based Prevention and Education Are Key While some actions are being taken to improve Africa’s response to gender-based violence including building police and judiciary systems that understand their roles and can prosecute cases of gender-based violence, more needs to be done about awareness-raising and education that can prevent crimes from ever occurring, stressed Byanyima. “In my view, we are weakest on prevention. You need aggressive campaigns discouraging violent behaviors of boys and men, especially the way they see their masculinity and how they exercise it. That discouragement still needs to happen,” Byanyima said. Presently, this duty is largely left to civil societies and women organisations, but Byanyima noted that it is the business of the government to invest in continual campaigning in communities to change how relationships can be managed without violence. Winnie Byanyima “This is about men’s behavior – the way men are raised and see themselves as men. Tackling toxic masculinity is something that is not well invested in,” she said. Another necessary action to tackle the silent pandemic is to empower girls and women in African societies. Citing data from HIV, the UNAIDS Executive Director noted that an African girl’s vulnerability to HIV, sexual violence, unintended pregnancy and early marriage reduce by up to 50% if she is able to complete high school. But while African leaders have ratified universal basic education requiring every child to get at least primary education, two-thirds of children in Africa do not have access to secondary education. “The time for secondary education has come. We fought for universal primary education in Beijing and within ten years we have achieved it. Now we need to draw the line and say every government worth its name must put its kids, boys and girls, through high school. Not only for the knowledge economy but also for the safety and empowerment of girls and fighting gender-based violence,” Byanyima said. Story of Success: Experts Laud Rwanda’s One Stop Center For Sexual Violence Bineta Diop, African Union’s Special Envoy on Women Peace & Security, recommended African governments adopting Rwanda’s one-stop center for sexual violence. Located within the Kacyiru Police Hospital, the Isange One Stop Centre, the Isange One Stop Center has become a hub for gender-based violence survivors. At the center, survivors can access all the required services in one place and for free. The center is operated by the country’s Gender and Family Promotion, of Health, and Justice ministries in addition to the Rwanda National Police. Bineta Diop The initiative that started in 2009 as a pilot has since been expanded across the country. Rwanda now has a One Stop Centre in every district. Every day, up to 12 survivors are received at the center. “28% are survivors of intimate partner violence and 78 percent are survivors of sexual violence. Of the 78% of survivors who have been sexually assaulted, 16% are younger than 5 years,” said Daniel Nyamwasa, Commissioner of Police and Chief Infectologist Consultant at the hospital. Diop also encouraged African governments to acquire DNA testing capabilities to provide evidence that could be used to prosecute cases of rape and other gender-based violence against women and girls. Enlisting More Women in Police and Judiciary Another solution is the enlistment of more women in the police and judiciary systems across the continent which Diop said will encourage more women to approach the legal system to file complaints. She also called for the engagement of Africa’s traditional leaders. “If you want to break the patriarchal system, you have to engage the traditional system,” Diop said. However, as the number of confirmed cases of COVID-19 in Africa is increasing, African governments are also focusing on how to quickly and safely reopen their economies to minimize the impact of the pandemic. This current reality threatens the materialization of recommendations giving more attention to combating gender-based violence. But Ramaphosa, for one, has said this does not have to be the case. In his comments last week, he stressed that action can and should be taken to combat violence, despite the numerous familiar and peculiar challenges that countries across the continent are facing: “For public faith in the criminal justice system to be maintained, gender-based violence needs to be treated with the urgency it deserves by our communities working together with our police.” Cyril Ramaphosa, President of South Africa Image Credits: Paul Adepoju, Twitter: Youth Alive Foundation, UN Women. Massive Mobilization Of US $31.3 Billion Required For COVID-19 Diagnostics, Drugs & Vaccines Accelerator 26/06/2020 Grace Ren Central Laboratory at the Academician Nikoloz Kipshidze University Clinic, Tbilisi, Georgia, receives laboratory equipment for COVID-19 diagnosis. The World Health Organization aims to raise a whopping US $31.3 billion to fund the ambitious goals of the Access to COVID-19 Tools (ACT) Accelerator; a multi-stakeholder initiative that aims to develop and deploy diagnostics, drugs, and vaccines to control the virus. But so far, only $US 3.4 billion has been pledged towards the initial goals. And US $13.7 billion is ‘urgently needed’ in order to cover immediate needs, according to an investment case released by WHO on Friday. “Though these numbers sound big, they are not. If we spend billions now, we will avoid spending trillions later. The time to act is now, and the way to act is together,” said Gavi Board Chair Ngozi Okonjo-Iweala. The funding will go toward: Scaling up development and delivery of 500 million diagnostic tests to low- and middle-income countries (LMICS) by mid-2021 Delivering 245 million courses of treatments to LMICs by mid-2021, Delivering 2 billion vaccine doses, of which 50% will go to LMICs by the end of 2021. “It’s clear that because all people are at risk of COVID-19, all people should have access to all the tools to prevent, detect and treated, not only those who can afford to pay for them,” said World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus at a Friday press briefing. “We have made the principle of equitable access a simple thing to say, but a complicated thing to implement.” Dr Tedros at the 26 June press briefing More than 9 million people have been infected, and nearly half a million have so far lost their lives to the virus. The investment required in the Accelerator is less than a tenth of the loss the global economy is facing every month due to the pandemic, according to International Monetary Fund estimates. “The cost of inaction now is quite important to take into consideration,” said Philippe Duneton, executive director of UNITAID, working with the Wellcome Trust on the therapeutics pillar of the project. A good portion of the immediate investments will go towards preparing markets to absorb new COVID-19 technologies, setting up demand, manufacturing, and country capacity to roll out any new diagnostics, vaccines, or drugs. Four Investment Pillars Require Urgent Funding The ACT Accelerator operates under four main pillars – diagnostics, therapeutics, vaccines, and the health systems connector. The diagnostics pillar, co-led by FIND and the Global Fund to Fight AIDS, Tuberculosis, and Malaria, aims to avoid 1.6 billion further infections by scaling up access to diagnostics. The pillar requires US $6 billion in the next year, but US $2 billion is urgently needed to begin deploying tests now. Ultimately, 10,000 healthcare workers will be needed. “The real strategy towards containing the epidemic is through testing, tracing, isolation; and the starting point for that is a very rapid rollout of very large numbers of tests,” said Peter Sands, executive director of the Global Fund. “To underscore the urgency for many lower middle income countries, lockdown is not sustainable. Households don’t have the wherewithal to continue without working, and governments don’t have the ability to compensate for lost income, coupled with the fact that clinical care facilities are extremely limited.” The therapeutics pillar will focus on accelerating the development and deployment of effective treatments. While no drugs have yet been tapped, the pillar aims to provide 250 million courses of treatment to LMICS in the next 12 months. Some US$11.6 billion is needed in the next year, while US $3.8 billion is needed immediately. “Of course, as soon as we have a medicine, the situation at the country level will also be a challenge,” said Duneton. “The access to oxygen, for example, is not the same in all countries.” But “the only way to prevent further transmission [of the virus] and to break that cycle, would be to have an effective and safe vaccine available to people,” said WHO Chief Scientist Soumya Swaminathan. Soumya Swaminathan speaks at the 26 June ACT Accelerator press briefing The vaccines pillar has an ambitious goal of delivering 2 billion doses by the end of 2021. Seven candidates are currently in clinical trials, but none have yet received regulatory approval. So far, the fastest vaccine to move from lab bench to approval for human use was the Ebola vaccine – which took five years to develop. “In general, it takes 8 to 10 years for a vaccine to move from when the research begins to when it gets into people. We want to shorten that timeline as short as possible – 12 months, 18 months maximum,” said Swaminathan. “That would be unprecedented, and can only happen through global collaboration.” The Coalition for Epidemic Preparedness Innovation (CEPI), and Gavi, the Vaccine Alliance, will lead the vaccines pillar alongside WHO, which will provide oversight of regulation, policy and allocation. Some US $18.1 billion is required to safely deliver the vaccine to people in need. Gavi, through an advanced market agreement under its COVAX Facility, aims to pool purchasing power from nations of all income levels to secure low vaccine prices. Some 950 million doses must be procured by self-financing, upper-middle and high income countries, in addition to the 2 billion doses set aside for lower income countries. A final pillar, the health systems connector, aims to strengthen the infrastructure and community networks required to deliver tools to people in need. Led by the World Bank, and the Global Fund, the pillar aims to build lab capacity, train staff to safely manage COVID-19, and to use new tools as they are deployed. Image Credits: Flickr: IAEA Imagebank/Natalia Khurtsidze, PR Manager of the Clinic. Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts This site uses cookies to help give you the best experience on our website. Cookies enable us to collect information that helps us personalise your experience and improve the functionality and performance of our site. By continuing to read our website, we assume you agree to this, otherwise you can adjust your browser settings. Please read our cookie and Privacy Policy. Our Cookies and Privacy Policy Loading Comments... You must be logged in to post a comment.
Massive Mobilization Of US $31.3 Billion Required For COVID-19 Diagnostics, Drugs & Vaccines Accelerator 26/06/2020 Grace Ren Central Laboratory at the Academician Nikoloz Kipshidze University Clinic, Tbilisi, Georgia, receives laboratory equipment for COVID-19 diagnosis. The World Health Organization aims to raise a whopping US $31.3 billion to fund the ambitious goals of the Access to COVID-19 Tools (ACT) Accelerator; a multi-stakeholder initiative that aims to develop and deploy diagnostics, drugs, and vaccines to control the virus. But so far, only $US 3.4 billion has been pledged towards the initial goals. And US $13.7 billion is ‘urgently needed’ in order to cover immediate needs, according to an investment case released by WHO on Friday. “Though these numbers sound big, they are not. If we spend billions now, we will avoid spending trillions later. The time to act is now, and the way to act is together,” said Gavi Board Chair Ngozi Okonjo-Iweala. The funding will go toward: Scaling up development and delivery of 500 million diagnostic tests to low- and middle-income countries (LMICS) by mid-2021 Delivering 245 million courses of treatments to LMICs by mid-2021, Delivering 2 billion vaccine doses, of which 50% will go to LMICs by the end of 2021. “It’s clear that because all people are at risk of COVID-19, all people should have access to all the tools to prevent, detect and treated, not only those who can afford to pay for them,” said World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus at a Friday press briefing. “We have made the principle of equitable access a simple thing to say, but a complicated thing to implement.” Dr Tedros at the 26 June press briefing More than 9 million people have been infected, and nearly half a million have so far lost their lives to the virus. The investment required in the Accelerator is less than a tenth of the loss the global economy is facing every month due to the pandemic, according to International Monetary Fund estimates. “The cost of inaction now is quite important to take into consideration,” said Philippe Duneton, executive director of UNITAID, working with the Wellcome Trust on the therapeutics pillar of the project. A good portion of the immediate investments will go towards preparing markets to absorb new COVID-19 technologies, setting up demand, manufacturing, and country capacity to roll out any new diagnostics, vaccines, or drugs. Four Investment Pillars Require Urgent Funding The ACT Accelerator operates under four main pillars – diagnostics, therapeutics, vaccines, and the health systems connector. The diagnostics pillar, co-led by FIND and the Global Fund to Fight AIDS, Tuberculosis, and Malaria, aims to avoid 1.6 billion further infections by scaling up access to diagnostics. The pillar requires US $6 billion in the next year, but US $2 billion is urgently needed to begin deploying tests now. Ultimately, 10,000 healthcare workers will be needed. “The real strategy towards containing the epidemic is through testing, tracing, isolation; and the starting point for that is a very rapid rollout of very large numbers of tests,” said Peter Sands, executive director of the Global Fund. “To underscore the urgency for many lower middle income countries, lockdown is not sustainable. Households don’t have the wherewithal to continue without working, and governments don’t have the ability to compensate for lost income, coupled with the fact that clinical care facilities are extremely limited.” The therapeutics pillar will focus on accelerating the development and deployment of effective treatments. While no drugs have yet been tapped, the pillar aims to provide 250 million courses of treatment to LMICS in the next 12 months. Some US$11.6 billion is needed in the next year, while US $3.8 billion is needed immediately. “Of course, as soon as we have a medicine, the situation at the country level will also be a challenge,” said Duneton. “The access to oxygen, for example, is not the same in all countries.” But “the only way to prevent further transmission [of the virus] and to break that cycle, would be to have an effective and safe vaccine available to people,” said WHO Chief Scientist Soumya Swaminathan. Soumya Swaminathan speaks at the 26 June ACT Accelerator press briefing The vaccines pillar has an ambitious goal of delivering 2 billion doses by the end of 2021. Seven candidates are currently in clinical trials, but none have yet received regulatory approval. So far, the fastest vaccine to move from lab bench to approval for human use was the Ebola vaccine – which took five years to develop. “In general, it takes 8 to 10 years for a vaccine to move from when the research begins to when it gets into people. We want to shorten that timeline as short as possible – 12 months, 18 months maximum,” said Swaminathan. “That would be unprecedented, and can only happen through global collaboration.” The Coalition for Epidemic Preparedness Innovation (CEPI), and Gavi, the Vaccine Alliance, will lead the vaccines pillar alongside WHO, which will provide oversight of regulation, policy and allocation. Some US $18.1 billion is required to safely deliver the vaccine to people in need. Gavi, through an advanced market agreement under its COVAX Facility, aims to pool purchasing power from nations of all income levels to secure low vaccine prices. Some 950 million doses must be procured by self-financing, upper-middle and high income countries, in addition to the 2 billion doses set aside for lower income countries. A final pillar, the health systems connector, aims to strengthen the infrastructure and community networks required to deliver tools to people in need. Led by the World Bank, and the Global Fund, the pillar aims to build lab capacity, train staff to safely manage COVID-19, and to use new tools as they are deployed. Image Credits: Flickr: IAEA Imagebank/Natalia Khurtsidze, PR Manager of the Clinic. Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts This site uses cookies to help give you the best experience on our website. Cookies enable us to collect information that helps us personalise your experience and improve the functionality and performance of our site. By continuing to read our website, we assume you agree to this, otherwise you can adjust your browser settings. Please read our cookie and Privacy Policy. Our Cookies and Privacy Policy
Emer Cooke Nominated As New European Medicines Agency Executive Director 25/06/2020 Svĕt Lustig Vijay Emer Cooke, new Executive Director of the European Medical Agency High-level WHO official Emer Cooke has been nominated as the head of the European Medicines Agency (EMA), the critical regulatory body for European health product approvals. Cooke, an Irish national with 30 years’ experience in international regulatory affairs, is currently the Director of the WHO’s Regulation and Prequalification Department since 2016. In this role, she leads WHO’s programme on prequalification approval for health products being procured and sold to low- and middle-income countries at concessionary prices, in close collaboration with Member States and international partners. Cooke’s work also involves quality assurance to ensure that health technologies perform to high standards, and in accordance with safety norms. she holds a degree in pharmacy and a Masters degrees in Science and in Business Administration, from Trinity College in Dublin, Ireland. At an extraordinary virtual session on 25 June, the Board selected Emer Cooke from a shortlist of candidates created by the European Commission. On 13 July, Cooke will give a statement to the European Parliament’s Committee on Environment, Public Health and Food Safety (ENVI). The appointment of the new Executive Director will only be finalized after that meeting. See the EMA’s press release for more details. Image Credits: EMA. Posts navigation Older postsNewer posts