Market failure

How little goes to neglected diseases. Circle areas are to scale

Note: in 1975–99, 16 of 1,393 new medicines marketed worldwide (1.1%) were for tropical diseases and TB.
Sources: Ashigbie et al., Nature Reviews Drug Discovery (2025); DNDi, MMV, TB Alliance and MDGH (2026), citing Policy Cures Research and IFPMA; Trouiller et al., The Lancet (2002)

Neglected diseases' share of new medicines and of private-sector health R&D spending
MeasureTotalFor neglected diseases
New medicines approved by the US FDA, 2005–2476315 (2.0%)
Private-sector health R&D spending100%Just under 2% for malaria, TB, HIV and diarrhoeal diseases; 0.2% for neglected tropical diseases
New medicines marketed worldwide, 1975–991,39316 for tropical diseases and TB (1.1%)